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61.发明授权公开(公告)号：US07465777B2
公开(公告)日：2008-12-16
申请号：US11366230
申请日：2006-03-02
IPC分类号： C08G77/442 , C08G77/02
CPC分类号： C08G77/42 , A61L27/26 , A61L27/34 , A61L29/049 , A61L29/085 , A61L31/041 , A61L31/10 , C08L51/06 , C08L83/10
摘要： The present disclosure relates to hybrid polymers, methods of making such hybrid polymers, and medical devices that include the hybrid polymers. Such hybrid polymers are suitable for forming biomaterials in a predetermined shape for use in medical devices and medical device components. The hybrid polymers of the present disclosure are formed through a reactive extrusion process prior to being formed into the predetermined shape of the medical device or medical device component.
摘要翻译： 本公开涉及混合聚合物，制备这种杂化聚合物的方法，以及包括杂化聚合物的医疗装置。 这样的混合聚合物适用于形成用于医疗装置和医疗装置部件的预定形状的生物材料。 本公开的混合聚合物在形成医疗装置或医疗装置部件的预定形状之前通过反应性挤出工艺形成。
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62.发明授权Minimum visibility seam tape and method of joining substrates using the same 失效最小可见度接缝带和使用其的接合基板的方法公开(公告)号：US06322657B1
公开(公告)日：2001-11-27
申请号：US09295032
申请日：1999-04-20
IPC分类号： B29C6500
CPC分类号： G09F13/08 , B29C65/38 , B29C65/4815 , B29C65/5021 , B29C65/5028 , B29C65/5042 , B29C65/7847 , B29C66/1142 , B29C66/43 , B29C66/71 , B29C66/721 , B29C66/7392 , B29C66/91411 , B29C66/9241 , B29C66/929 , B29K2313/00 , G09F7/00 , Y10T428/19 , Y10T428/197 , Y10T428/20 , Y10T442/178 , Y10T442/198 , B29K2077/00 , B29K2023/04 , B29K2023/10 , B29K2075/00 , B29K2067/00 , B29K2027/06 , B29K2023/12 , B29K2023/06
摘要： A minimum visibility seam tape and method of joining at least two substrates with the tape. The substrates joined typically are sign faces or awnings comprising a composite of thermoplastics and a woven scrim. The seam tape is a woven or nonwoven scrim embedded in or coated with a thermoplastic polymer.
摘要翻译： 最小可见度接缝带和将至少两个基底与带接合的方法。 连接的基底通常是包括热塑性塑料和编织稀松布的复合材料的标志面或遮篷。 接缝带是嵌入或涂覆有热塑性聚合物的织造或无纺布。
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公开(公告)号：US4902378A
公开(公告)日：1990-02-20
申请号：US187028
申请日：1988-04-27
CPC分类号： C08J7/047 , B29C59/16 , B29C71/0063 , B29C2035/0827 , B29K2027/06 , B29K2105/0005 , B29K2995/0039 , B29K2995/0041 , C08J2327/06
摘要： Semicrystalline polymers and copolymers having migratory additives therein can be provided with reduced migration. A surface layer of the polymer of copolymer article is rendered quasi-amorphous and a film less penetrable by said migratory additives than the polymer or copolymer is adhered thereto.
摘要翻译： 可以提供其中具有迁移添加剂的半结晶聚合物和共聚物具有降低的迁移。 共聚物制品的聚合物的表面层被制成准无定形的，并且与聚合物或共聚物粘附的所述迁移添加剂不易渗透的膜。
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公开(公告)号：US20100298769A1
公开(公告)日：2010-11-25
申请号：US12783024
申请日：2010-05-19
CPC分类号： A61L27/54 , A61L27/20 , A61L29/043 , A61L29/16 , A61L31/042 , A61L31/16 , A61L2300/416 , A61L2300/42 , C08L5/08 , C08L5/10
摘要： Various aspects of the invention relate to implantable medical devices, which comprise a layer of material (e.g., in the form of a sheet, tube, etc.) that comprises a bioerodible polymer and a therapeutic agent. Other aspects of the invention relate to methods of forming such devices. Still other aspects of the invention relate to methods of treatment using such devices.
摘要翻译： 本发明的各个方面涉及可植入医疗装置，其包括包含生物可腐蚀聚合物和治疗剂的材料层（例如，片状，管状等）。 本发明的其它方面涉及形成这种装置的方法。 本发明的其它方面涉及使用这种装置的治疗方法。
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公开(公告)号：US07723422B2
公开(公告)日：2010-05-25
申请号：US11317614
申请日：2005-12-23
IPC分类号： C08K3/40
CPC分类号： A61L31/128 , A61L27/446 , A61L29/126 , C08K9/02 , C08K9/04 , C08K2201/013 , C08L53/00
摘要： Reinforced copolymers formed from a functionalized copolymer that undergoes a reactive extrusion process with an inorganic component to form the reinforced copolymer. The functionalized copolymer in the form of a block and/or graft copolymer includes hard segments and soft segments, where the soft segments are covalently bonded with a coupling agent either before or after copolymerization with the hard segments. The reinforced copolymer of the present disclosure can be suitable for use as a biomaterial and/or in medical devices.
摘要翻译： 由官能化共聚物形成的增强共聚物，其经历与无机组分的反应性挤出方法以形成增强共聚物。 嵌段和/或接枝共聚物形式的官能化共聚物包括硬链段和软链段，其中软链段在与硬链段共聚合之前或之后与偶联剂共价键合。 本公开的增强共聚物可适用于生物材料和/或医疗装置。
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公开(公告)号：US5260113A
公开(公告)日：1993-11-09
申请号：US688648
申请日：1991-04-19
CPC分类号： G09F13/08 , B29C65/4815 , B29C65/5042 , B29C66/1142 , B29C66/43 , B29C66/721 , B29C66/7392 , G09F7/00 , B29C65/38 , B29C65/5021 , B29C65/5028 , B29C65/7847 , B29C66/71 , B29C66/91411 , B29C66/9241 , B29C66/929 , B29K2313/00 , Y10T428/19 , Y10T428/197 , Y10T428/20 , Y10T442/178 , Y10T442/198
摘要： A minimum visibility seam tape and method of joining at least two substrates with the tape. The substrates joined typically are sign faces or awnings comprising a composite of thermoplastics and a woven scrim. The seam tape is a woven or nonwoven scrim embedded in or coated with a thermoplastic polymer.
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公开(公告)号：US5032209A
公开(公告)日：1991-07-16
申请号：US187024
申请日：1988-04-27
摘要： Semicrystalline polymers can have predetermined amounts of their surfaces rendered quasi-amorphous by irradiation. Polymer surfaces which are so modified can display enhanced heat sealability to accept bonding to other materials.
摘要翻译： 半结晶聚合物可以通过照射使预定量的表面呈现准非晶态。 如此改性的聚合物表面可以显示增强的热封性以接受与其它材料的粘合。
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公开(公告)号：US4879176A
公开(公告)日：1989-11-07
申请号：US186813
申请日：1988-04-27
CPC分类号： C08J7/047 , B05D3/063 , B29C59/16 , B29C71/0063 , C08J5/121 , B29C2035/0827 , B29C2035/0838 , B29K2995/0039 , B29K2995/0041 , C08J2327/06 , C08J2367/02 , Y10T428/25 , Y10T428/265 , Y10T428/31 , Y10T428/3154 , Y10T428/31544 , Y10T428/31551 , Y10T428/31739 , Y10T428/31786 , Y10T428/31913 , Y10T428/31931 , Y10T428/31938
摘要： Semicrystalline polymers can have predetermined amounts of their surfaces rendered quasi-amorphous by irradiation. Polymer surfaces which are so modified can display enhanced ability to accept bonding to other materials.
摘要翻译： 半结晶聚合物可以通过照射使预定量的表面呈现准非晶态。 如此改性的聚合物表面可以显示增强的接受与其它材料粘结的能力。
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公开(公告)号：US08187623B2
公开(公告)日：2012-05-29
申请号：US12491467
申请日：2009-06-25
CPC分类号： C08G61/08 , A61L31/06 , A61L31/10 , C08G61/12 , C08G2261/147 , C08G2261/3324 , C08G2261/3342 , C08G2261/418
摘要： Medical copolymers are provided which comprise (a) a polymer backbone comprising (i) a plurality of —C═C— groups within the polymer backbone, (ii) a plurality of —R9— groups within the polymer backbone, wherein R9 comprises a radical-substituted C2-C10 cyclic or heterocyclic group, or (iii) both a plurality of —C═C— groups and a plurality of —R9— groups within the polymer backbone, (b) a plurality of hydrocarbon-based pendant groups along the polymer backbone that comprise a saturated or unsaturated carbon chain of at least four carbons in length, and (c) a plurality of zwitterionic pendant groups along the polymer backbone that comprise a positively charged quaternary ammonium group and a negatively charged phosphate group. Methods of forming such copolymers, medical products that contain such copolymers, and methods of making such medical products are also disclosed.
摘要翻译： 提供医疗共聚物，其包含（a）聚合物主链，其包含（i）聚合物主链内的多个-C≡C-基团，（ii）聚合物主链内的多个-R9-基团，其中R9包含基团 - 取代的C 2 -C 10环状或杂环基团，或（iii）聚合物主链内的多个-C≡C-基团和多个-R9-基团，（b）多个基于烃基的侧基 包括长度为至少四个碳的饱和或不饱和碳链的聚合物主链，和（c）沿聚合物主链的多个两性离子侧基，其包含带正电荷的季铵基和带负电荷的磷酸基。 还公开了形成这种共聚物的方法，含有这些共聚物的医药产品，以及制造这种医药产品的方法。
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公开(公告)号：US20120101525A1
公开(公告)日：2012-04-26
申请号：US13278910
申请日：2011-10-21
申请人： Mark L. Jenson , Jason P. Hill , James Q. Feng , David J. Sogard , Robert W. Warner , Patrick A. Haverkost
发明人： Mark L. Jenson , Jason P. Hill , James Q. Feng , David J. Sogard , Robert W. Warner , Patrick A. Haverkost
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/0404 , A61B2017/0417 , A61B2017/06185
摘要： A device for sealing an opening in a vessel includes an anchor attached to a suture. The anchor is inserted through the opening into the vessel, and the suture pulls the anchor against the vessel wall, forming a seal. A plug is inserted over the suture and is axially compressed toward the anchor, locking the elements in place. The suture is braided or woven outside of the anchor so that it may be stored and handled easily, and is unbraided, unwoven and/or untangled at its distal end inside the anchor, so that individual filaments within the suture may extend laterally within the anchor. The laterally extending filaments subtend a larger footprint within the anchor than a comparable footprint if the suture were to remain braided or tied into a knot within the anchor, which may more effectively distribute the retaining forces within the anchor.
摘要翻译： 用于密封容器中的开口的装置包括附接到缝合线的锚固件。 锚固件通过开口插入容器中，并且缝合线将锚固件拉靠在血管壁上，形成密封。 将塞子插入缝合线上并朝向锚固件轴向压缩，将元件锁定就位。 该缝合线被编织或编织在锚定体之外，使得其可以容易地储存和处理，并且在其锚固体内部的远端处是未被覆盖的，无纺的和/或解开的，使得缝合线内的单个细丝可以在锚定件内横向延伸 。 横向延伸的长丝在锚固体内对着较大的覆盖区域，而不是如果缝合线保持编织或连接到锚固体内的结，这可以更有效地将锚定力分配在锚固体内。
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