公开(公告)号：US5968967A

公开(公告)日：1999-10-19

申请号：US51085

申请日：1998-04-13

申请人： Keizo Tanikawa ,  Takashi Matsumoto ,  Masumi Nakamura ,  Yasunori Asada ,  Norimasa Shudo

发明人： Keizo Tanikawa ,  Takashi Matsumoto ,  Masumi Nakamura ,  Yasunori Asada ,  Norimasa Shudo

IPC分类号： A61K31/415 ,  A61K31/44 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/47 ,  A61K31/495 ,  A61P7/02 ,  A61P9/08 ,  A61P9/10 ,  C07D231/12 ,  C07D231/14 ,  C07D231/20 ,  C07D231/22 ,  C07D401/04 ,  C07D401/06 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06

CPC分类号： C07D231/12 ,  C07D231/14 ,  C07D231/20 ,  C07D231/22 ,  C07D401/04 ,  C07D401/06 ,  C07D401/14 ,  C07D403/04

摘要： A pyrazolone derivative represented by general formula (I) or a salt thereof: ##STR1## [wherein one of X.sup.1 and X.sup.2 is ##STR2## (wherein A is a cyano group, a cyano C.sub.1-4 alkyl group, an amino group, an amino C.sub.1-4 alkyl group, an amidino group or a guanidino group, R.sup.1 and R.sup.2 are independently hydrogen atoms, halogen atoms, C.sub.1-6 alkyl groups or the like) or the like],the other of X.sup.1 and X.sup.2 is a C.sub.1-6 alkyl group, a C.sub.3-6 alkenyl group, an aryl C.sub.1-4 alkyl group or an aryl group,one of Y.sup.1 and Y.sup.2 is ##STR3## (wherein Q is an oxygen atom or a sulfur atom, Z.sup.1 is an oxygen atom, a --NR.sup.7 -- group or a --CHR.sup.7 -- group, Z.sup.2 is a cyclic C.sub.3-7 alkylene group, a C.sub.1-3 alkylene group, a --CH.sub.2 CO-- group or --CH.sub.2 CH.sub.2 CO-- group, Z.sup.3 is an oxygen atom, a sulfur atom, a sulfinyl group, a sulfonyl group or the like, Z.sup.4 is a C.sub.1-3 alkylene group, and Z.sup.5 is a carboxyl group or the like, andthe other of Y.sup.1 and Y.sup.2 is a D-E- group [wherein E is a bond, a C.sub.1-4 alkylene group or a phenylene group, and D is a hydrogen atom, a C.sub.1-6 alkyl group or the like which has an inhibitory action on platelet aggregation and is useful as a preventive or therapeutic agent for various thrombotic diseases.

摘要翻译： PCT No.PCT / JP96 / 02944 Sec。 371日期：1998年4月13日 102（e）1998年4月13日PCT PCT 1996年10月11日PCT公布。 第WO97 / 13757号公报 日本1997年4月17日由通式（I）表示的吡唑啉酮衍生物或其盐：其中X1和X2之一为（其中A为氰基，氰基C1-4烷基，氨基，氨基 C 1-4烷基，脒基或胍基，R 1和R 2独立地为氢原子，卤素原子，C 1-6烷基等），X 1和X 2中的另一个为C 1-6 烷基，C 3-6烯基，芳基C 1-4烷基或芳基，Y1和Y2之一为（其中Q为氧原子或硫原子，Z1为氧原子，-NR7- 基团或-CHR7-基团，Z2为环状C3-7亚烷基，C1-3亚烷基，-CH2CO-基或-CH2CH2CO-基，Z3为氧原子，硫原子，亚磺酰基， 磺酰基等，Z4为C1-3亚烷基，Z5为羧基等，Y1和Y2中的另一个为DE-基[其中E为键，C1-4亚烷基 基团或亚苯基，D为氢原子，C1-6烷基 对血小板聚集具有抑制作用，可用作各种血栓性疾病的预防或治疗剂。

公开(公告)号：US5891347A

公开(公告)日：1999-04-06

申请号：US782256

申请日：1997-01-14

申请人： Takashi Matsumoto

发明人： Takashi Matsumoto

IPC分类号： B04B3/00 ,  B04B11/08 ,  B04B15/12 ,  B01D33/06 ,  B01D35/18

CPC分类号： B04B11/08 ,  B04B3/00

摘要： Centrifugal filtration capable of improving recovery of crystal in a baskey. The basket is so arranged that a central axis thereof is inclined with respect to a horizontal direction to obliqely downwardly orientate a bottom wall of the basket. A crystal recovery auction pipe is arranged which includes a pivotally movable section pivotally moved in the basket, of which a distal end is advanced into crystal in the basket. Crystal in the basket is recovered by suction through the distal end of the suction pipe, which is ultimately displaced to a corner of the basket between a lowermost portion of a peripheral wall of the basket and a bottom wall thereof. This permits crystal collected to a lowermost section of the basket to be substantially recovered by suction through the suction pipe, to thereby improve crystal recovery.

摘要翻译： 离心过滤能够提高碱洗中晶体的回收率。 篮子被布置成使得其中心轴线相对于水平方向倾斜以使篮子的底壁方向倾斜地向下定向。 布置了一种晶体回收拍卖管，其包括在篮中枢转运动的可枢转运动部分，其中远端在篮中进入晶体。 通过抽吸回收篮子中的水晶，其最终移动到篮子的一个角落之间，最后位于篮子周围壁的最下部和底壁之间。 这允许收集到篮子的最下部分的晶体通过吸入管基本回收，从而改善晶体回收率。

公开(公告)号：US5750523A

公开(公告)日：1998-05-12

申请号：US676227

申请日：1996-07-23

申请人： Keizo Tanikawa ,  Takashi Matsumoto ,  Hiroo Matsumoto ,  Nobutomo Tsuruzoe ,  Hitoshi Nakabeppu

发明人： Keizo Tanikawa ,  Takashi Matsumoto ,  Hiroo Matsumoto ,  Nobutomo Tsuruzoe ,  Hitoshi Nakabeppu

IPC分类号： C07D237/22 ,  C07D401/12 ,  A61K31/50

CPC分类号： C07D401/12 ,  C07D237/22

摘要： Pyridazinone derivatives represented by the formula (I) and antiplatelet agents containing them: ##STR1## �wherein R is a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group, X is a hydrogen atom, a chlorine atom or a bromine atom, Ar is a pyridyl group or a phenyl group substituted with OR.sup.1 (wherein R.sup.1 is a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group) and A {wherein A is a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkyl group or OR.sup.2 (wherein R.sup.2 is a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group)}, is C.sub.1 -C.sub.8 alkylene wherein one carbon atom on the straight chain is substituted with one OR.sup.1 group (wherein R.sup.1 is the same as defined above), and Z.sup.1 and Z.sup.2 are independently a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkyl group or a OR.sup.1 group (wherein R.sup.1 is the same as defined above)!. These compounds have strong antiplatelet effects, are excellently safe, and can be used as active ingredients of prophylactic and therapeutic drugs for various thrombotic diseases.

摘要翻译： PCT No.PCT / JP95 / 00069 Sec。 371日期：1996年7月23日 102（e）日期1996年7月23日PCT提交1995年1月24日PCT公布。 WO95 / 19969 PCT公开 日期：1997年7月27日由式（I）表示的哒嗪酮衍生物和含有它们的抗血小板剂：其中R是氢原子或C1-C4烷基，X是氢原子，氯原子 或溴原子，Ar是吡啶基或被OR 1取代的苯基（其中R1是氢原子或C1-C4烷基）和A {其中A是氢原子，卤原子，C1-C4 烷基或OR 2（其中R 2是氢原子或C 1 -C 4烷基）}是其中一个碳原子被一个OR 1基团取代的C 1 -C 8亚烷基（其中R 1与上述定义相同） ，Z 1和Z 2独立地为氢原子，卤素原子，C 1 -C 4烷基或OR 1基（其中R 1与上述定义相同）]。 这些化合物具有很强的抗血小板作用，非常安全，可用作各种血栓性疾病的预防和治疗药物的活性成分。

公开(公告)号：US5550695A

公开(公告)日：1996-08-27

申请号：US346583

申请日：1994-11-29

申请人： Takashi Matsumoto

发明人： Takashi Matsumoto

IPC分类号： G11B21/12 ,  G11B5/54

CPC分类号： G11B5/54

摘要： A magnetic disk apparatus having an unloading member for unloading a magnetic head from the surface of the magnetic disk when the driving of the same is stopped. One end of a spring arm has a magnetic head attached thereto and the other end of the spring arm is joined to a head arm which is rotated by a voice coil motor. The unloading member is set up on the base for rotation in a plane parallel to the plane of rotation of the head arm and has a first arm whose one end is capable of slide contacting the spring arm and a second arm whose one end is capable of abutting on the head arm. The one end of the first arm is beveled to facilitate its slide contact with the spring arm. The second arm of the unloading member is urged by a torsion spring in the direction of the head arm. When the driving is stopped, the magnetic head is moved to the outer side of the magnetic disk, so that the head arm abuts on the one end of the second arm. Thereby, the one end of the first arm is rotated toward the magnetic head so that the spring arm comes into slide contact with the beveled end of the first arm and goes on the first arm and, thus, the magnetic head becomes supported by the unloading member.

摘要翻译： 一种具有卸载部件的磁盘装置，用于当其驱动停止时从磁盘表面卸载磁头。 弹簧臂的一端具有安装在其上的磁头，弹簧臂的另一端与通过音圈马达旋转的头臂接合。 卸载部件设置在基座上以在与头臂的旋转平面平行的平面中旋转，并且具有第一臂，其一端能够滑动地接触弹簧臂和第二臂，其一端能够 靠在头臂上。 第一臂的一端是倾斜的，以便于其与弹簧臂的滑动接触。 卸载部件的第二臂由扭簧沿头臂的方向推压。 当驱动停止时，磁头移动到磁盘的外侧，使得头臂抵靠第二臂的一端。 由此，第一臂的一端朝向磁头旋转，使得弹簧臂与第一臂的倾斜端部滑动接触，并且在第一臂上移动，因此磁头通过卸载而被支撑 会员。

公开(公告)号：US5340732A

公开(公告)日：1994-08-23

申请号：US854845

申请日：1992-03-20

申请人： Noriyuki Habuka ,  Masashi Miyano ,  Takashi Matsumoto ,  Masana Noma

发明人： Noriyuki Habuka ,  Masashi Miyano ,  Takashi Matsumoto ,  Masana Noma

IPC分类号： A61K38/00 ,  A61K47/48 ,  A61P31/12 ,  C07K14/00 ,  C07K14/415 ,  C12N1/21 ,  C12N15/09 ,  C12N15/29 ,  C12P21/02 ,  C12R1/19 ,  C12N9/12 ,  C12N15/54 ,  C12N15/70

CPC分类号： C07K14/415 ,  A61K47/48438 ,  A61K47/48484 ,  A61K38/00 ,  C07K2319/00 ,  C07K2319/02

摘要： An antiviral protein having an amino acid sequence represented by sequence No. 8 of a Sequence Listing is disclosed. The protein is obtained such that cysteine residues in the basic protein (MAP) obtained from Mirabilis jalapa and having antiviral activity are substituted with serine residues. More specifically, a MAP gene in which codons encoding cysteines are substituted with codons encoding serines is prepared, and this gene is integrated in a MAP secretion vector. This vector is introduced into a host to express the gene, thereby obtaining the antiviral protein. This protein retains MAP advantages as a toxic protein and has higher protein synthesis inhibition activity than that of MAP, and almost equal to that of a lysine A chain.

摘要翻译： 公开了具有由序列表的序列号8表示的氨基酸序列的抗病毒蛋白质。 获得蛋白质，使得从Mirabilis jalapa获得并具有抗病毒活性的碱性蛋白质（MAP）中的半胱氨酸残基被丝氨酸残基取代。 更具体地，制备其中编码半胱氨酸的密码子被编码丝氨酸的密码子替代的MAP基因，并将该基因整合到MAP分泌载体中。 将该载体导入宿主以表达基因，从而获得抗病毒蛋白质。 该蛋白质保留了作为毒性蛋白质的MAP优点，并且具有比MAP更高的蛋白质合成抑制活性，并且几乎等于赖氨酸A链的蛋白质合成抑制活性。

公开(公告)号：US5204543A

公开(公告)日：1993-04-20

申请号：US918117

申请日：1992-07-22

申请人： Toshio Hanazawa ,  Yukinori Fujimura ,  Takashi Matsumoto

发明人： Toshio Hanazawa ,  Yukinori Fujimura ,  Takashi Matsumoto

IPC分类号： G03G13/28 ,  B41C1/10 ,  H01L27/082 ,  H01L29/735

CPC分类号： H01L27/0821 ,  H01L29/735

摘要： A semiconductor device comprises a substrate of a first conduction type defined by a major surface, a pair of conductive regions of a second conduction type formed in the substrate along the major surface, an intervening region of the first conduction type formed in the substrate between the pair of conductive regions so as to separate the pair of conductive regions from each other, a first insulator film provided on the substrate so as to cover the major surface thereof including the pair of conductive regions and the intervening region located therebetween, a first conductor layer provided so as to extend generally parallel to the major surface of the substrate with a separation from the first insulator film, the first conductor layer crossing a part of the intervening region at a level separated therefrom, a second conductor layer provided on the first insulator film at a level below the first conductor layer so as to cover at least the part of the intervening region which is crossed by the first conductor layer, a second insulator film interposed between the second conductor layer and the first conductor layer, and a circuit for applying a predetermined voltage to the second conductor layer, the predetermined voltage having a magnitude chosen such that turning-on of a parasitic MOS transistor formed in the semiconductor device is eliminated.

摘要翻译： 半导体器件包括由主表面限定的第一导电类型的衬底，沿着主表面形成在衬底中的第二导电类型的一对导电区域，形成在衬底中的第一导电类型的中间区域 一对导电区域，以将一对导电区域彼此分离;第一绝缘膜，设置在基板上以覆盖其主表面，包括一对导电区域和位于其间的中间区域;第一导体层 所述第一导体层与所述第一绝缘体膜分开地大致平行于所述基板的主表面延伸，所述第一导体层以与其分开的水平度与所述中间区域的一部分交叉;第二导体层，设置在所述第一绝缘膜上 在低于第一导体层的水平处，以至少覆盖交错的中间区域的部分 d，由第二导体层和第一导体层之间插入的第二绝缘体膜，以及用于向第二导体层施加预定电压的电路，所述预定电压的大小被选择为使得导通 形成在半导体器件中的寄生MOS晶体管被消除。

公开(公告)号：US5202323A

公开(公告)日：1993-04-13

申请号：US768182

申请日：1991-10-16

申请人： Keizo Tanikawa ,  Akira Saito ,  Takashi Matsumoto ,  Ryozo Sakoda ,  Nobutomo Tsuruzoe ,  Ken-ichi Shikada

发明人： Keizo Tanikawa ,  Akira Saito ,  Takashi Matsumoto ,  Ryozo Sakoda ,  Nobutomo Tsuruzoe ,  Ken-ichi Shikada

IPC分类号： A61K31/50 ,  A61K31/501 ,  A61P7/02 ,  C07D237/22 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D409/14 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12

CPC分类号： C07D401/12 ,  C07D237/22 ,  C07D405/12

摘要： A compound of the formula, ##STR1## or its pharmaceutically acceptable salt, and its preparation process and pharmaceutical compositions characterized by containing these compounds as effective ingredients.These compounds have strong antithrombotic activity, cardiotonic activity, vasodilator activity and anti-SRS-A activity, and are useful as prophylactic or therapeutic agents for various thrombotic affections, congestive heart failure, hypertension, asthma, immediate type allergy diseases and the like.

公开(公告)号：US5181066A

公开(公告)日：1993-01-19

申请号：US887816

申请日：1992-05-26

申请人： Yoshio Ozawa ,  Takashi Matsumoto ,  Kimitoshi Saito

发明人： Yoshio Ozawa ,  Takashi Matsumoto ,  Kimitoshi Saito

IPC分类号： B65H20/36 ,  G03B1/00 ,  G03B27/46 ,  G03B27/58

CPC分类号： G03B27/462 ,  G03B27/588

摘要： A paper transporting device for a photographic printer. A pulse motor starts rotating during a magazine setting operation. The rotation of the pulse motor is transmitted to a pair of feed rollers through a pin-clutch mechanism and a paper feed gear train. Immediately before a paper magazine is completely attached to the photographic printer, the feed rollers nip the leading end of photographic paper and pull the photographic paper out of the paper magazine. When changing the paper magazine, a solenoid is turned on to change over the pin-clutch mechanism from the paper feed gear train to a paper rewind gear train. Thereafter, the pulse motor is rotated in reverse, so as to rotate a winding shaft of the paper magazine through the pin-clutch mechanism and the paper rewind gear train. An unexposed portion of the photographic paper remaining in the photographic printer is thus wound back into the paper magazine.

摘要翻译： 一种用于照相打印机的纸张传送装置。 脉冲电机在刀库设置操作期间开始旋转。 脉冲电机的旋转通过销离合器机构和进纸齿轮系传递到一对进给辊。 在纸盒完全连接到照相打印机之前，进纸辊将紧贴相纸的前端，并将相纸从纸盒中拉出。 更换纸盒时，打开一个电磁线圈，将引脚离合器机构从进纸齿轮组切换到纸张重绕齿轮系。 此后，脉冲电动机反向旋转，从而通过销离合器机构和纸张倒带齿轮系旋转纸盒的卷绕轴。 剩下在照相打印机中的照相纸的未曝光部分因此被卷回到纸盒中。

公开(公告)号：US5072178A

公开(公告)日：1991-12-10

申请号：US532447

申请日：1990-06-04

申请人： Takashi Matsumoto

发明人： Takashi Matsumoto

IPC分类号： G01R31/317 ,  G01R31/3183 ,  G01R31/319 ,  G06F11/22

CPC分类号： G01R31/31919 ,  G01R31/31908 ,  G01R31/31926 ,  G06F2201/865

摘要： A testing method of a logic circuit which can change test data in a testing apparatus and an apparatus which is used for the testing method are disclosed. The logic circuit testing apparatus having a first storage to store test data including a plurality of test patterns and a second storage to store each of the test patterns in correspondence to a group of tester pins further has a transfer circuit including a data converter to change the test patterns from the first storage and a third storage to store control data to control the data converter. The transfer circuit transfers each of the test patterns from the first storage to the second storage. When the test pattern is transferred by the transfer circuit, the test pattern is changed by the data converter by the control data.

摘要翻译： 公开了可以改变测试装置中测试数据的逻辑电路的测试方法和用于测试方法的设备。 具有第一存储器的逻辑电路测试装置具有存储包括多个测试图案的测试数据的第一存储器和用于存储与一组测试器引脚相对应的每个测试模式的第二存储器，还具有包括数据转换器的转移电路， 来自第一存储器的测试模式和第三存储器来存储控制数据以控制数据转换器。 传送电路将每个测试图案从第一存储器传送到第二存储器。 当测试图案由传送电路传送时，由数据转换器通过控制数据改变测试图案。

公开(公告)号：US5040083A

公开(公告)日：1991-08-13

申请号：US506732

申请日：1990-04-10

申请人： Takashi Matsumoto ,  Taichi Takesa

发明人： Takashi Matsumoto ,  Taichi Takesa

IPC分类号： G11B5/012 ,  G11B5/016 ,  G11B5/48

CPC分类号： G11B5/4886 ,  G11B5/012 ,  G11B5/016

摘要： A combined magnetic head system for recording a data track on a guard band between main tracks of a floppy disk. The system includes a control device for controlling a transfer mechanism so that the level of a second signal becomes equal to that of a third signal during the recording of a first signal, or so that the level of a first signal is maximized during the reproduction thereof, or so that a level of one of the reproduced second or third signals is maximized during the recording of the first signal. A guard band data head for data tracks is positioned above the guard band and has width so as to record satisfactorily data on the guard band without degrading recorded information on the main tracks irrespective of whether the recording is performed with the data head stretching over the main tracks. The width is preferably between 40% and 60% of the guard band.