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公开(公告)号:US20200029868A1
公开(公告)日:2020-01-30
申请号:US16371155
申请日:2019-04-01
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Christopher M. Hobot , Martin T. Gerber
Abstract: The invention relates to devices, systems, and methods for estimating a patient BUN level prior to a dialysis session based on data received when introducing an ammonium removal solution through a zirconium phosphate sorbent module. The systems and methods can introduce an ammonia removal solution and determine an ammonia content of the ammonium removal solution effluent to estimate the patient pre-dialysis BUN level.
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公开(公告)号:US10537875B2
公开(公告)日:2020-01-21
申请号:US15942229
申请日:2018-03-30
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Christopher M. Hobot , Martin T. Gerber
Abstract: The invention relates to devices, systems, and methods for recharging zirconium phosphate and/or zirconium oxide in reusable sorbent modules. The devices, systems, and methods provide for precision recharging of the zirconium phosphate and/or zirconium oxide to avoid the need of excess recharge solutions. The devices systems and methods also provide for calculation of the volumes of recharge solution needed for fully recharging the zirconium phosphate and zirconium oxide modules.
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公开(公告)号:US20190224399A1
公开(公告)日:2019-07-25
申请号:US16369817
申请日:2019-03-29
Applicant: Medtronic, Inc.
Inventor: Kenneth J. Collier , Christopher M. Hobot , Martin T. Gerber , Bryant J. Pudil
Abstract: The invention relates to devices, systems, and methods for recharging zirconium phosphate. The devices, system, and methods use a patient pre-dialysis BUN level to set one or more recharge parameters for recharging the zirconium phosphate. The devices, systems, and methods allow for precision recharging of the zirconium phosphate based on the patient pre-dialysis BUN level.
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公开(公告)号:US20180221852A1
公开(公告)日:2018-08-09
申请号:US15942229
申请日:2018-03-30
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Christopher M. Hobot , Martin T. Gerber
CPC classification number: B01J20/3475 , A61M1/1607 , A61M1/1611 , A61M1/1654 , A61M1/1692 , A61M1/1696 , A61M2202/0225 , A61M2205/3303 , A61M2205/3334 , B01J20/0211 , B01J20/0292 , B01J20/06 , B01J20/3433 , B01J20/3483 , B01J39/09
Abstract: The invention relates to devices, systems, and methods for recharging zirconium phosphate and/or zirconium oxide in reusable sorbent modules. The devices, systems, and methods provide for precision recharging of the zirconium phosphate and/or zirconium oxide to avoid the need of excess recharge solutions. The devices systems and methods also provide for calculation of the volumes of recharge solution needed for fully recharging the zirconium phosphate and zirconium oxide modules.
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公开(公告)号:US10010663B2
公开(公告)日:2018-07-03
申请号:US13757693
申请日:2013-02-01
Applicant: Medtronic, Inc.
Inventor: Thomas E. Meyer , David B. Lura , Bryant J. Pudil , Martin T. Gerber
CPC classification number: A61M1/1621 , A61M1/1601 , A61M1/1652 , A61M1/1656 , A61M1/1658 , A61M1/1664 , A61M1/1668 , A61M1/3465 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649
Abstract: A flow loop for hemodialysis, hemodiafiltration and hemofiltration for the treatment of pathological conditions such as End Stage Renal Disease (ESRD) that has a controlled compliant flow path for preparing fluids required for a hemodialysis therapy session from water. The controlled compliant flow path modifies water into any one of a solution for priming a hemodialysis system, a physiologically compatible solution for contacting blood, a physiologically compatible solution for infusion to a subject, and a solution for blood rinse back to a subject. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the flow path.
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公开(公告)号:US09974896B2
公开(公告)日:2018-05-22
申请号:US14642847
申请日:2015-03-10
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , SuPing Lyu , Eric Grovender , Christopher M. Hobot , Martin T. Gerber
CPC classification number: A61M1/1696 , B01J39/09 , C01B25/45
Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing combinations of acids, bases and salts through a module containing a rechargeable sorbent material such as zirconium phosphate in order to replace ions bound to the zirconium phosphate with hydrogen and sodium ions. The method allows for a customizable zirconium phosphate, with control over the ratios of sodium to hydrogen on the recharged zirconium phosphate.
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公开(公告)号:US09713666B2
公开(公告)日:2017-07-25
申请号:US13836538
申请日:2013-03-15
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Thomas E. Meyer , David B. Lura , Martin T. Gerber
CPC classification number: A61M1/1696 , A61M1/14 , A61M1/1605 , A61M1/1613 , A61M1/1619 , A61M1/165 , A61M1/1694 , A61M1/28 , A61M1/3406 , A61M1/3472 , A61M2202/0498 , A61M2205/15 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , B01D15/08 , B01D15/362
Abstract: A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in fluid communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood in a blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.
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公开(公告)号:US20170112991A1
公开(公告)日:2017-04-27
申请号:US15398069
申请日:2017-01-04
Applicant: MEDTRONIC, INC.
Inventor: Bryant J. Pudil , Thomas E. Meyer , David B. Lura , Martin T. Gerber
Abstract: A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in fluid communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood in a blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.
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公开(公告)号:US09132217B2
公开(公告)日:2015-09-15
申请号:US13844599
申请日:2013-03-15
Applicant: Medtronic, Inc.
Inventor: Orhan Soykan , Bryant J. Pudil , Thomas E. Meyer , Linda L. Ruetz , Carl Schu
IPC: A61M1/14 , A61B5/00 , A61M1/16 , A61M1/34 , A61B5/145 , B01D61/32 , B01D65/02 , B01D61/24 , B01D61/30 , A61B5/0452 , A61B5/0488 , A61M1/36 , A61B5/026 , A61B5/053 , A61B5/021
CPC classification number: A61M1/14 , A61B5/0031 , A61B5/021 , A61B5/026 , A61B5/0452 , A61B5/0488 , A61B5/0537 , A61B5/145 , A61B5/4848 , A61B5/6866 , A61B2560/0223 , A61M1/16 , A61M1/1601 , A61M1/1607 , A61M1/1609 , A61M1/1613 , A61M1/1696 , A61M1/28 , A61M1/341 , A61M1/342 , A61M1/3427 , A61M1/3458 , A61M1/3609 , A61M2205/18 , A61M2205/332 , A61M2205/3331 , A61M2205/3334 , A61M2205/3553 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/70 , A61M2230/005 , A61M2230/04 , A61M2230/207 , A61M2230/208 , A61M2230/60 , A61M2230/65 , B01D61/243 , B01D61/30 , B01D61/32 , B01D65/02 , B01D2311/246 , B01D2321/12 , B01D2321/40
Abstract: A dialysis device for operation in multiple modes and for maintaining a known gradient of potassium ion or other electrolyte between the blood of a patient and a dialysate fluid is described. The dialysis device is capable of being used for hemodialysis or peritoneal dialysis, and the dialysis device is capable of operation with a dialysate purification unit outside of a clinical setting or with a supply of water that can be supplied in a clinical setting. The dialysis device has a composition sensor containing a potassium-sensitive electrode for measuring a potassium ion concentration in one or more of the patient's blood and the dialysate fluid and an infusate pump operated to adjust a potassium ion concentration in the dialysate fluid based at least in part on data from the composition sensor.
Abstract translation: 描述了用于在多种模式中操作并用于在患者血液和透析液之间维持已知梯度的钾离子或其他电解质的透析装置。 透析装置能够用于血液透析或腹膜透析,并且透析装置能够在临床环境之外的透析液净化单元或能够在临床环境中供应的水的供给下进行操作。 该透析装置具有含有用于测量患者血液和透析液中的一种或多种中的钾离子浓度的钾敏感电极的成分传感器,以及至少在以下方式调节透析液中的钾离子浓度的输液泵 部分来自组合传感器的数据。
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70.
公开(公告)号:US20150114891A1
公开(公告)日:2015-04-30
申请号:US14555414
申请日:2014-11-26
Applicant: MEDTRONIC, INC.
Inventor: Thomas E. Meyer , David B. Lura , Bryant J. Pudil , Martin T. Gerber
Abstract: A portable dialysis cabinet for use in dialysis. The portable dialysis cabinet can have a size and weight that facilitates easy movement of the cabinet from one location to another with relative ease. The portable dialysis cabinet can have additional features necessary to facilitate portability, such as wheels and a handle. In general, the portable dialysis cabinet can contain all the necessary components for performing a dialysis session.
Abstract translation: 用于透析的便携式透析柜。 便携式透析柜可以具有尺寸和重量,其有助于容易地将柜从一个位置移动到另一个位置。 便携式透析柜可以具有促进便携性所必需的附加功能,例如轮子和手柄。 通常,便携式透析柜可以包含用于执行透析会话的所有必要组件。
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