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61.
公开(公告)号:US5478733A
公开(公告)日:1995-12-26
申请号:US90198
申请日:1993-07-16
申请人: Ryoichi Katsumata , Shinichi Hashimoto , Isao Kawamoto , Makoto Suzuki , Hajime Yoshida , Hiroshi Hagino , Kiyoshi Nakayama
发明人: Ryoichi Katsumata , Shinichi Hashimoto , Isao Kawamoto , Makoto Suzuki , Hajime Yoshida , Hiroshi Hagino , Kiyoshi Nakayama
CPC分类号: C12P13/06 , Y10S435/83
摘要: A process for producing L-alanine, which comprises culturing in a medium a microorganism belonging to the genus Arthrobacter which has L-alanine dehydrogenase activity, but little or no alanine racemase activity, and which is capable of producing L-alanine; allowing L-alanine to accumulate in the culture; and recovering L-alanine from the culture.
摘要翻译: 一种生产L-丙氨酸的方法,其包括在培养基中培养具有L-丙氨酸脱氢酶活性但几乎不具有丙氨酸脱水酶活性的节杆菌属的微生物,并且能够产生L-丙氨酸; 允许L-丙氨酸在培养物中积累; 并从培养物中回收L-丙氨酸。
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公开(公告)号:US5424306A
公开(公告)日:1995-06-13
申请号:US151517
申请日:1993-11-12
申请人: Isao Kawamoto , Masao Miyauchi , Roruro Endo
发明人: Isao Kawamoto , Masao Miyauchi , Roruro Endo
IPC分类号: C07D477/00 , A61K31/397 , A61K31/40 , A61P31/04 , C07D477/16 , C07D477/20 , A01N43/00 , A61K31/395 , C07D487/04
CPC分类号: C07D477/20
摘要: A storage stable form of the pivaloyloxymethyl ester of the carbapenem derivative known as (1R, 5S, 6S)-2-[(4R)-2-oxo-4-pyrrolidinylthio]-6-[(1R)-1-hydroxyethyl]-1-methyl-1-carbapen-2-em-3-carboxylic acid in crystalline form.
摘要翻译: 称为(1R,5S,6S)-2 - [(4R)-2-氧代-4-吡咯烷硫基] -6 - [(1R)-1-羟乙基] - 1-甲基-1-碳代青霉-2-烯-3-羧酸。
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公开(公告)号:US5066817A
公开(公告)日:1991-11-19
申请号:US516304
申请日:1990-04-30
申请人: Hirofumi Nakano , Mitsunobu Hara , Tsuyoshi Mokudai , Isao Kawamoto , Mayumi Yoshida , Eiji Kobayashi
发明人: Hirofumi Nakano , Mitsunobu Hara , Tsuyoshi Mokudai , Isao Kawamoto , Mayumi Yoshida , Eiji Kobayashi
IPC分类号: C07D407/04 , C12P17/06
CPC分类号: C07D407/04 , C12P17/06 , Y10S435/886
摘要: Disclosed are DC115A compounds represented by the following general formula: ##STR1## wherein R represents ethyl, propyl or 1-propenyl, and which have antibacterial and anti-tumor activity. DC115A compounds are produced by culturing a microorganism belonging to the genus Streptomyces.
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64.
公开(公告)号:US4593097A
公开(公告)日:1986-06-03
申请号:US575294
申请日:1984-01-30
申请人: Fusao Tomita , Keiichi Takahashi , Isao Kawamoto , Kozo Asano , Makoto Morimoto , Tadashi Ashizawa , Kazuhisa Fujimoto
发明人: Fusao Tomita , Keiichi Takahashi , Isao Kawamoto , Kozo Asano , Makoto Morimoto , Tadashi Ashizawa , Kazuhisa Fujimoto
IPC分类号: A61K31/495 , A61P1/04 , A61P31/04 , A61P35/00 , C07D241/46 , C12P17/12 , C12R1/465
CPC分类号: C12P17/12 , C07D241/46
摘要: Phenazine compounds represented by the formula: ##STR1## wherein R is a hydrogen atom, an unsubstituted or substituted lower alkanoyl group, or an unsubstituted or substituted arylcarbonyl group have antibacterial and anti-tumor activities.Some of these compounds are produced by incubation of a microorganism.
摘要翻译: 由下式表示的吩嗪化合物:其中R为氢原子,未取代或取代的低级烷酰基或未取代或取代的芳基羰基具有抗菌和抗肿瘤活性。 这些化合物中的一些通过温育微生物产生。
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公开(公告)号:US3976768A
公开(公告)日:1976-08-24
申请号:US490668
申请日:1974-07-22
申请人: Takashi Nara , Seigo Takasawa , Ryo Okachi , Isao Kawamoto , Mitsuyoshi Yamamoto , Seiji Sato , Tomoyasu Sato
发明人: Takashi Nara , Seigo Takasawa , Ryo Okachi , Isao Kawamoto , Mitsuyoshi Yamamoto , Seiji Sato , Tomoyasu Sato
IPC分类号: C07H15/224 , C12P1/06 , C12P19/48 , A61K35/00
CPC分类号: C07H15/224 , Y10S435/863
摘要: A new antibiotic, Fortimicin A, is produced by fermentation of a microorganism belonging to the genus Micromonospora. The antibiotic is accumulated in the culture medium and is isolated therefrom.
摘要翻译: 一种新的抗生素Fortimicin A是通过微生物属于小单孢菌属的发酵产生的。 抗生素在培养基中积聚并从中分离。
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