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公开(公告)号：US07147838B2
公开(公告)日：2006-12-12
申请号：US11025636
申请日：2004-12-29
IPC分类号： A61K49/00
CPC分类号： A61K51/088 , A61K38/00 , C07F5/003 , C07F15/008 , C07K7/086 , C07K14/57572
摘要： A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor.
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公开(公告)号：US20050163710A1
公开(公告)日：2005-07-28
申请号：US11025636
申请日：2004-12-29
IPC分类号： G01N33/566 , A61K38/00 , A61K51/00 , A61K51/08 , A61P35/00 , C07F5/00 , C07F15/00 , C07K7/06 , C07K7/08 , C07K14/575 , C07K14/79
CPC分类号： A61K51/088 , A61K38/00 , C07F5/003 , C07F15/008 , C07K7/086 , C07K14/57572
摘要： A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor.
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63.发明授权Trailer of an automatically scanning-type radiation inspection system for large-sized object 有权用于大型物体的自动扫描式辐射检测系统的拖车公开(公告)号：US06837657B2
公开(公告)日：2005-01-04
申请号：US10712872
申请日：2003-11-13
申请人： Jianmin Li , Wenhuan Gao , Yinong Liu , Jianjun Su , Ning Li , Wanquan Shen , Rongxuan Liu
发明人： Jianmin Li , Wenhuan Gao , Yinong Liu , Jianjun Su , Ning Li , Wanquan Shen , Rongxuan Liu
CPC分类号： G01V5/0008 , B61J3/06
摘要： A trailer of an automatically scanning-type radiation inspecting system used for large-sized object, comprising a trailer body provided with a bevel portion at a tail end of a top surface thereof and positioning recesses adaptive to lower portions of front wheels of a vehicle carrying objects to be inspected respectively, a plurality of pairs of guide wheels mounted to a bottom surface of the trailer body and can be supported and run on rails, connection rods provided at front and rear ends of the bottom surface of the trailer body and used for connecting to wire ropes of winches respectively, anchoring hooks provided at front and rear ends of the bottom surface of the trailer body and used for engaging with wedges arranged on the ground, and holding means provided at front and back sides of the positioning recesses and used for holding the front wheels of the vehicle in the positioning recesses during movement of the trailer. During operation of the trailer of present invention, the trailer pulls the vehicle carrying objects to be inspected to pass through the inspection passage smoothly while the front wheels of the vehicle are held in the positioning recesses on the trailer and rear wheels thereof roll over the ground. The trailer-conveying apparatus formed by the trailer of the present invention and winches occupies less land, being low in cost, simple in structure, reasonable in design, advantageous to shield the radiation, and easy to be maintained.
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公开(公告)号：US06200546B1
公开(公告)日：2001-03-13
申请号：US09064499
申请日：1998-04-22
IPC分类号： A61K4900
CPC分类号： A61K51/088 , A61K38/00 , C07F5/003 , C07F15/008 , C07K7/086 , C07K14/57572
摘要： A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor.
摘要翻译： 用作治疗或诊断性放射性药物的化合物包括能够使与能够结合胃泌素释放肽受体的部分连接的医学上有用的金属络合的基团。 用于治疗患有肿瘤疾病的受试者的方法包括向受试者施用有效量的具有与螯合基螯合的金属的放射性药物，所述螯合基团连接到能够结合肿瘤细胞上表达的胃泌素释放肽受体的部分，随后内化 的细胞。 形成治疗或诊断化合物的方法包括使金属合成酶与能够结合胃泌素释放肽受体的部分共价连接的螯合基团反应。
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65.发明公开公开(公告)号：US20230351432A1
公开(公告)日：2023-11-02
申请号：US18138114
申请日：2023-04-23
申请人： Hongwei Zhu , Ning Li
发明人： Hongwei Zhu , Ning Li
IPC分类号： G06Q30/0226 , G06Q20/38 , G06Q30/0601 , G06Q20/40 , G06Q20/12 , G06Q20/06 , G06Q20/10
CPC分类号： G06Q30/0233 , G06Q20/389 , G06Q20/38215 , G06Q20/3829 , G06Q20/3825 , G06Q30/0637 , G06Q20/4014 , G06Q20/12 , G06Q20/065 , G06Q20/381 , G06Q20/108 , G06Q30/0609
摘要： System and method of providing secured coupon redemption with reward distribution in a blockchain (BC) network. A merchant pays for coupon coins to the BC network. When a consumer attempts to redeem a coupon associated with a purchase order, both the merchant and the consumer digitally sign a redemption request and send to the BC network for validation. The request may contain an encrypted order, an encrypted consumer key and an encrypted consumer key, and both signatures. Upon successful validation, the BC network can execute a smart contract to deduct the coupon coin balance and issue reward in the form of BC ownership coin to involved parties.
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公开(公告)号：US09694442B2
公开(公告)日：2017-07-04
申请号：US13470432
申请日：2012-05-14
申请人： Ning Li , Qin Ping Zhao
发明人： Ning Li , Qin Ping Zhao
CPC分类号： B23K26/14 , B23K1/0016 , B23K1/0056 , B23K3/0623 , B23K26/1476 , B23K26/60 , B23K2101/42
摘要： An apparatus for forming electrical solder connections in a disk drive unit includes: a nozzle device for carrying out soldering on two pre-welding surfaces; a solder ball feeding device for transferring a single solder ball to the nozzle device; a gas pump device for supplying pressurized gases to the nozzle device; a laser device for emitting laser beams to the solder ball; and a control device including at least one sensor for at least detecting status of the solder ball or pressure in the nozzle device or distance between the nozzle device and the pre-welding surfaces, and a control unit connected with the at least one sensor. The present invention can easily control the solder ball, the pressurized gases and the laser beams, thereby keeping the pressure of the nozzle device and the laser energy stable and, in turn improving the soldering result.
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67.发明授权Oral solid formulation of compound anti-tubercular drug and preparation method thereof 有权复方抗结核药的口服固体制剂及其制备方法公开(公告)号：US09555003B2
公开(公告)日：2017-01-31
申请号：US14111323
申请日：2012-04-10
申请人： Maojian Gu , Qilan Zheng , Chao Xu , Ning Li , Guixian Chen , Lan Zheng , Min Wang , Lintao Jiang
发明人： Maojian Gu , Qilan Zheng , Chao Xu , Ning Li , Guixian Chen , Lan Zheng , Min Wang , Lintao Jiang
IPC分类号： A61K9/28 , A61K31/133 , A61K31/4965 , A61K31/496 , A61K31/4409 , A61K9/20 , A61K9/24
CPC分类号： A61K9/286 , A61K9/2086 , A61K9/209 , A61K9/28 , A61K9/284 , A61K9/2866 , A61K9/2886 , A61K31/133 , A61K31/4409 , A61K31/496 , A61K31/4965 , A61K2300/00
摘要： Provided is an oral solid preparation of a compound anti-tubercular drug, wherein the active ingredients are rifampicin, isoniazid, pyrazinamide and ethambutol hydrochloride. The compound oral solid preparation is a coated tablet with coated core or a coated three-layer tablet, wherein the two active ingredients rifampicin and isoniazid do not come to contact with each other directly. The compound oral solid preparation not only improves the stability of the compound preparation, but also improves the bioavailability of rifampicin.
摘要翻译： 本发明提供化合物抗结核药物的口服固体制剂，其中活性成分为利福平，异烟肼，吡嗪酰胺和盐酸乙胺丁醇。 复合口服固体制剂是具有包衣核心或涂覆的三层片剂的包衣片剂，其中两种活性成分利福平和异烟肼不直接相互接触。 复方口服固体制剂不仅提高了化合物制剂的稳定性，而且提高了利福平的生物利用度。
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公开(公告)号：US20140273524A1
公开(公告)日：2014-09-18
申请号：US14204490
申请日：2014-03-11
申请人： Victor Nguyen , Mihaela Balseanu , Li-Qun Xia , Ning Li , Martin A. Hilkene , Matthew D. Scotney-Castle
发明人： Victor Nguyen , Mihaela Balseanu , Li-Qun Xia , Ning Li , Martin A. Hilkene , Matthew D. Scotney-Castle
IPC分类号： H01L21/02
CPC分类号： H01L21/02321 , H01L21/0214 , H01L21/0217 , H01L21/0228 , H01L21/0234 , H01L21/31155
摘要： Provided are methods for the deposition and doping of films comprising Si. Certain methods involve depositing a SiN, SiO, SiON, SiC or SiCN film and doping the Si-containing film with one or more of C, B, O, N and Ge by a plasma implantation process. Such doped Si-containing films may have improved properties such as reduced etch rate in acid-based clean solutions, reduced dielectric constant and/or improved dielectric strength.
摘要翻译： 提供了用于沉积和掺杂包含Si的膜的方法。 某些方法包括沉积SiN，SiO，SiON，SiC或SiCN膜，并通过等离子体注入工艺将C，B，O，N和Ge中的一种或多种掺杂到含Si薄膜。 这种掺杂的含Si薄膜可具有改进的性能，例如在酸基清洁溶液中降低的蚀刻速率，降低的介电常数和/或改善的介电强度。
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公开(公告)号：US08775371B2
公开(公告)日：2014-07-08
申请号：US12616679
申请日：2009-11-11
申请人： Ronald J. Barber , Harish Deshmukh , Ning Li , Bruce G. Lindsay , Sridhar Rajagopalan , Roger C. Raphael , Eugene J. Shekita
发明人： Ronald J. Barber , Harish Deshmukh , Ning Li , Bruce G. Lindsay , Sridhar Rajagopalan , Roger C. Raphael , Eugene J. Shekita
IPC分类号： G06F17/30
CPC分类号： G06F17/30578 , G06F17/30545
摘要： Techniques are disclosed for synchronizing a primary data system with an auxiliary data system that processes data for the primary data system. In one embodiment, how current the primary data system and the auxiliary data system are is determined. Requests sent from the primary data system that were not processed by the auxiliary data system are determined. The requests are resent to the auxiliary data system for processing.
摘要翻译： 公开了用于使主数据系统与处理主数据系统的数据的辅助数据系统同步的技术。 在一个实施例中，确定主数据系统和辅助数据系统的当前时间。 确定从主数据系统发送的未被辅助数据系统处理的请求。 请求重新发送到辅助数据系统进行处理。
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70.发明授权公开(公告)号：US08738673B2
公开(公告)日：2014-05-27
申请号：US12875615
申请日：2010-09-03
申请人： Ronald Jason Barber , Harish Deshmukh , Ning Li , Bruce Gilbert Lindsay , Sridhar Rajagopalan , Roger C. Raphael , Eugene J. Shekita , Paul Sherwood Taylor
发明人： Ronald Jason Barber , Harish Deshmukh , Ning Li , Bruce Gilbert Lindsay , Sridhar Rajagopalan , Roger C. Raphael , Eugene J. Shekita , Paul Sherwood Taylor
IPC分类号： G06F17/30
CPC分类号： G06F17/30233 , G06F17/30584 , G06F17/30631
摘要： Provided are techniques for partitioning a physical index into one or more physical partitions; assigning each of the one or more physical partitions to a node in a cluster of nodes; for each received document, assigning an assigned-doc-ID comprising an integer document identifier; and, in response to assigning the assigned-doc-ID to a document, determining a cut-off of assignment of new documents to a current virtual-index-epoch comprising a first set of physical partitions and placing the new documents into a new virtual-index-epoch comprising a second set of physical partitions by inserting each new document to a specific one of the physical partitions in the second set using one or more functions that direct the placement based on one of the assigned-doc-id, a field value derived from a set of fields obtained from the document, and a combination of the assigned-doc-id and the field value.
摘要翻译： 提供了用于将物理索引分割成一个或多个物理分区的技术; 将一个或多个物理分区中的每一个分配给节点簇中的节点; 对于每个接收到的文档，分配包括整数文档标识符的分配文档ID; 并且响应于将分配的文档ID分配给文档，确定新文档的分配到当前虚拟索引时期的截断，该当前虚拟索引时期包括第一组物理分区，并将新文档放入新的虚拟 - 指数 - 历元包括第二组物理分区，通过使用一个或多个基于所分配的文档ID中的一个来指导所述布局的功能，将每个新文档插入第二组中的特定一个物理分区 从文档获得的一组字段中导出的值以及分配的doc-id和字段值的组合。
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