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61.发明申请公开(公告)号：US20190172605A1
公开(公告)日：2019-06-06
申请号：US16270354
申请日：2019-02-07
Applicant: Hideo HOSONO , Yoshitake TODA , Katsuro HAYASHI , Setsuro ITO , Satoru WATANABE , Naomichi MIYAKAWA , Toshinari WATANABE , Kazuhiro ITO
Inventor： Hideo HOSONO , Yoshitake TODA , Katsuro HAYASHI , Setsuro ITO , Satoru WATANABE , Naomichi MIYAKAWA , Toshinari WATANABE , Kazuhiro ITO
Abstract: Disclosed herein is an amorphous C12A7 electride thin film which has an electron density of greater than or equal to 2.0×1018 cm−3 and less than or equal to 2.3×1021 cm−3, and exhibits a light absorption at a photon energy position of 4.6 eV. Also disclosed herein is an amorphous thin film which is fabricated using a target made of a crystalline C12A7 electride, and containing an electride of an amorphous solid material includig calcium, aluminum, and oxygen, in which an Al/Ca molar ratio of the thin film is 0.5 to 4.7.
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公开(公告)号：US20190169420A1
公开(公告)日：2019-06-06
申请号：US16321083
申请日：2017-08-01
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor： Hiroshi YABU
IPC: C08L53/00 , C08J7/06 , H01M8/0228 , H01M8/1004
Abstract: The problem addressed by the present invention is to provide a block copolymer that can be used in a neutral solvent atmosphere and can produce a solid polymer membrane including nanoparticles.The problem is solved by a block copolymer represented by formula (1) below. wherein in the formula, R1 represents a C1-20 linear, branched, or cyclic alkyl group, C6-20 aryl group, or C7-20 aralkyl group; R2 represents a group having a functional group having an acid dissociation constant pKa of from 0.5 to 7; R3, R4, and R5 each show H or a C1-20 linear, branched, or cyclic alkyl group; R6, R7, and R8 each represent a hydrogen, hydroxyl group, nitro group, carboxy group, or carbonyl group; X represents an amide or ester, but may not be included; Y represents an amide or ester, but may not be included; p represents an integer of 1-10, but may not be included; n represents an integer of 3-1000; m represents an integer of 3-1000; and t represents an integer of 3-1000, but n may not be included; the arrangement of n, m, and t is arbitrary, but n and m are adjacent when n is included.
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公开(公告)号：US10301672B2
公开(公告)日：2019-05-28
申请号：US15527560
申请日：2015-11-18
Applicant: Japan Science and Technology Agency
Inventor： Masayuki Su'etsugu , Hiroko Kobayashi
IPC: C12Q1/68 , C12P19/34 , C12N15/00 , C12Q1/6844 , C12N9/00 , C12N9/12 , C12N9/16 , C12N9/90 , C12N15/09 , C12Q1/6853 , C12Q1/686
Abstract: The present invention provides a method for easily and exponentially amplifying circular DNA, particularly long chain circular DNA, in a cell-free system. Specifically, the present invention provides a method for amplifying circular DNA in which circular DNA having a replication origin sequence (origin of chromosome (oriC)) is mixed with a reaction solution containing the following enzyme groups to form a reaction mixture, which is then reacted under an isothermal condition, the enzyme groups being: (1) a first enzyme group that catalyzes replication of circular DNA; (2) a second enzyme group that catalyzes an Okazaki fragment maturation and synthesizes two sister circular DNAs constituting a catenane; and (3) a third enzyme group that catalyzes a separation of two sister circular DNAs.
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公开(公告)号：US10296496B2
公开(公告)日：2019-05-21
申请号：US14342264
申请日：2012-07-05
Applicant: Hiroshi Deguchi
Inventor： Hiroshi Deguchi
Abstract: A data storage unit of a data editing apparatus stores both a base indicating a data attribute and a data value in association with each other as data to be edited. A code acquisition unit acquires a user code, which is a code described in a first program language for describing data editing details by intensive notation and which describes editing details for the data to be edited that are based on the base. A code generation unit generates, in accordance with a predetermined correspondence relationship between a second program language for describing data editing details by extensive notation and the first program language, an execution code described in the second program language based on the user code. An editing processing unit edits the data to be edited in accordance with the execution code.
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公开(公告)号：US10249402B2
公开(公告)日：2019-04-02
申请号：US14567047
申请日：2014-12-11
Applicant: TOKYO INSTITUTE OF TECHNOLOGY , ASAHI GLASS COMPANY, LIMITED , JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor： Hideo Hosono , Yoshitake Toda , Katsuro Hayashi , Setsuro Ito , Satoru Watanabe , Naomichi Miyakawa , Toshinari Watanabe , Kazuhiro Ito
Abstract: A C12A7 electride thin film fabrication method includes a step of forming an amorphous C12A7 electride thin film on a substrate by vapor deposition under an atmosphere with an oxygen partial pressure of less than 0.1 Pa using a target made of a crystalline C12A7 electride having an electron density within a range of 2.0×1018 cm−3 to 2.3×1021 cm−3.
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Patent Agency Ranking
公开(公告)号：US20190062751A1
公开(公告)日：2019-02-28
申请号：US15569559
申请日：2016-04-22
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor： Kiyoko FUKAMI , Reiko SATOW
IPC: C12N15/113 , A61P35/04 , C12Q1/6886
CPC classification number: C12N15/1135 , A61K31/713 , A61K45/00 , A61K48/00 , A61P35/04 , C07K14/4702 , C12N2310/14 , C12Q1/6886 , C12Q2600/158
Abstract: The present invention provides an anti-tumor agent and a suppressor for suppressing malignant transformation such as acquisition of metastatic ability or acquisition of apoptosis resistance of a tumor cell. The present invention provides a tumor cell malignant transformation suppressor, including a substance suppressing or inhibiting Zic5 gene functions as an active ingredient to suppress or inhibit acquisition of metastatic ability or acquisition of apoptosis resistance of a tumor cell; a method of suppressing tumor cell malignant transformation of animals other than humans, including suppressing or inhibiting Zic5 gene functions to suppress or inhibit acquisition of metastatic ability or acquisition of apoptosis resistance of a tumor cell; an anti-tumor agent including a substance suppressing or inhibiting Zic5 gene functions as an active ingredient, in which the agent is used in prostate cancer therapy; and a marker for tumor cell malignancy consisting of the expression level of Zic5 gene.
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67.发明申请公开(公告)号：US20190041620A1
公开(公告)日：2019-02-07
申请号：US16076627
申请日：2017-02-09
Applicant: Japan Science and Technology Agency
Inventor： Hideharu MIKAMI , Keisuke GODA
CPC classification number: G02B21/06 , G02B21/0056 , G02B21/0068 , G02B21/0076 , G02F1/11 , G02F1/33 , G02F2203/22
Abstract: Provided are an irradiation device, a laser microscope system, an irradiation method, and a laser microscope detection method which can further widen a bandwidth of detection light as a multiplexed signal. Laser light beams are separated and enter a first AOD (24) and a second AOD (34) so that a plurality of first diffracted light beams and a plurality of second diffracted light beams with deflection angles and sizes of frequency shifts different from each other are generated. The first diffracted light beams and the second diffracted light beams are superposed by a beam splitter (19) so as to generate a plurality of interference light beams with beat frequencies different from each other. An objective lens (52) is formed by aligning a plurality of irradiation spots of interference light beam linearly in a main scanning direction and irradiates a sample (T) with the interference light beam. The irradiation spot is moved by oscillation of a scanning mirror (47a) in a sub scanning direction orthogonal to the main scanning direction. Fluorescence emitted from the sample (T) by irradiation of each interference light beam is detected by a light detection unit (13).
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公开(公告)号：US20190031820A1
公开(公告)日：2019-01-31
申请号：US15527639
申请日：2015-11-16
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor： Hiroshi YABU , Yuta SAITO , Shohei SAITO , Shigehiro YAMAGUCHI , Shunpei NOBUSUE
CPC classification number: C08G61/08 , C07D209/70 , C08G2261/122 , C08G2261/135 , C08G2261/3324 , C08G2261/418 , C08G2261/522 , C08G2261/62 , C08G2261/76 , C09K9/02 , C09K11/06 , G01L1/24
Abstract: Provided is a mechanochromic resin by which a stress applied to a material can be visualized in real time, and a mechanochromic luminescent material that is used in the synthesis of the mechanochromic resin. Stress can be visualized in real time by means of a mechanochromic luminescent material represented by formula (1) or formula (2) and a mechanochromic resin obtained by crosslinking the mechanochromic luminescent material. [Chemical formula 1] (In the formula, Y1 and Y2 each denote a substituent group that inhibits aggregation of the mechanochromic luminescent material represented by formula (1), and Y1 and Y2 may be same as or different from each other. Z1 and Z2 each denote a polymerizable group, and may be same as or different from each other.) [Chemical formula 2] (In the formula, Y1 and Y2 each denote a substituent group that inhibits aggregation of the mechanochromic luminescent material represented by formula (2), and Y1 and Y2 may be same as or different from each other. Z1 and Z2 each denote a polymerizable group, and may be same as or different from each other.)
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公开(公告)号：US10190952B2
公开(公告)日：2019-01-29
申请号：US14426809
申请日：2013-03-07
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor： Makoto Fujita , Yasuhide Inokuma , Shota Yoshioka , Junko Ariyoshi
IPC: C30B29/54 , G01N1/28 , C07D401/14 , C07D311/30 , C07D307/92 , C30B7/06 , C30B29/58 , B05D1/18 , G01N23/207 , G01N31/22
Abstract: The present invention is: a guest-compound-enveloping polymer-metal-complex crystal characterized by at least one selected from an aliphatic hydrocarbon, an alicyclic hydrocarbon, an ether, an ester, an aromatic hydrocarbon, a halogenated hydrocarbon, and a nitrile being enveloped as a guest compound (A) in the minute pores or the like of a polymer-metal complex that contains a metal ion as a central metal and a ligand having at least two ligating sites, has a 3D network structure formed by the ligand being ligated to the metal ion, and has the minute pores or the like regularly arranged three-dimensionally within the 3D network structure, the amount of the guest compound (A) present within the minute pores or the like being at least 60 mol % of all the guest compounds enveloped in the minute pores or the like; a method for producing the guest-compound-enveloping polymer-metal-complex crystal; a method for preparing a crystal structure analysis sample using the crystal; and a method for determining the molecular structure of an organic compound using the sample obtained by said method.
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公开(公告)号：US20190017937A1
公开(公告)日：2019-01-17
申请号：US16133867
申请日：2018-09-18
Applicant: Japan Science and Technology Agency
Inventor： Takeharu Nagai , Yoshiyuki Arai , Kazushi Suzuki
Abstract: A biological specimen containing a chemiluminescence substance that generates chemiluminescence is observed in a living state under a microscope. The microscope includes a light source that outputs control light that changes the state of the chemiluminescence, a defining unit that defines the radiation pattern of the control light with which an observation surface of the biological specimen is irradiated, and a detector that detects the chemiluminescence from the biological specimen.
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