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103 条记录 (耗时 0.019 秒)

    Extraction of B-vitamins from plant matter
    61.
    发明授权
    Extraction of B-vitamins from plant matter 有权
    从植物物质中提取B族维生素

    公开(公告)号：US09327006B2

    公开(公告)日：2016-05-03

    申请号：US14131262

    申请日：2012-07-30

    申请人： Ramaswamy Rajendran ,  Kamala Rajendran

    发明人： Ramaswamy Rajendran ,  Kamala Rajendran

    IPC分类号： A01N65/00 ,  A61K36/752 ,  C07D475/06 ,  A61K36/53 ,  A61K36/61

    CPC分类号： A61K36/752 ,  A61K31/16 ,  A61K31/4406 ,  A61K31/4415 ,  A61K31/51 ,  A61K31/519 ,  A61K31/525 ,  A61K36/53 ,  A61K36/61 ,  C07D415/00 ,  C07D475/06 ,  C07D475/14 ,  C07H1/08 ,  C07H23/00

    摘要： A process for the extraction of the B group of vitamins from a first plant matter is disclosed wherein, prior to the said extraction operation, the first plant matter is treated with a second plant matter comprising acidic compounds. The acidification converts the vitamins into more water-soluble forms and increases the yield thereof. In one example, the first plant matter comprises guava fruit matter, holy basil leaves and lemon peels, the two last-mentioned plant species being the source of the acidic compounds. The vitamins extracted and the proportions thereof may be controlled by suitable choice of the plant species constituting the first and second plant matters and their quantities, such as to give a substantially ready formulation conforming to RDA values or other requirements. The vitamins extracted are B1, B2, B3, B5, B6 and B9, the above combination of plant matters giving a higher yield than others. The process is of general applicability to other plant constituents.

    摘要翻译： 公开了从第一植物物质中提取B族维生素的方法，其中在所述提取操作之前，用包含酸性化合物的第二植物物质处理第一植物物质。 酸化将维生素转化为更多的水溶性形式并提高其产率。 在一个实例中，第一植物物质包括番石榴果实物质，圣罗勒叶和柠檬皮，两种最后提到的植物物种是酸性化合物的来源。 提取的维生素及其比例可以通过合适选择构成第一和第二植物物质及其数量的植物物种来进行控制，例如给出符合RDA值或其它要求的基本准备的制剂。 提取的维生素是B1，B2，B3，B5，B6和B9，上述植物物质组合比其他物质产量高。 该方法对其他植物成分具有普遍适用性。

    Method for the production of riboflavin of modification b/c in granular form
    64.
    发明授权
    Method for the production of riboflavin of modification b/c in granular form 失效
    用于生产颗粒形式的改性b / c的核黄素的方法

    公开(公告)号：US07329748B2

    公开(公告)日：2008-02-12

    申请号：US10552137

    申请日：2004-04-07

    申请人： Dirk Franke ,  Friedrich Hill ,  Christoph Martin ,  Thomas Knebel

    发明人： Dirk Franke ,  Friedrich Hill ,  Christoph Martin ,  Thomas Knebel

    IPC分类号： C07D487/04

    CPC分类号： C07D475/14 ,  A23L33/15

    摘要： The present invention relates to an improved process for preparing riboflavin of the B/C modification in granule form. Furthermore, the invention relates to the riboflavin preparation process wherein riboflavin of the A modification is (a) dissolved in aqueous mineral acid without treating the resulting riboflavin solution with activated carbon, (b) precipitated directly afterwards, steps (a) and (b) being carried out at a temperature in the range from 5 to 15° C., and (c) dried by fluidized bed granulation; and wherein the riboflavin does not come into contact with the aqueous mineral acid solvent for longer than on average 4 hours.

    摘要翻译： 本发明涉及一种制备颗粒形式的B / C改性核黄素的改进方法。 此外，本发明涉及核黄素制备方法，其中A修饰的核黄素是（a）溶解在无机酸水溶液中，而不用活性炭处理所得的核黄素溶液，（b）直接沉淀，步骤（a）和（b） 在5至15℃的温度下进行，（c）通过流化床造粒干燥; 并且其中所述核黄素不与无机酸水溶液接触长于平均4小时。

    Isoalloxazine derivatives to neutralize biological contaminants
    65.
    发明授权
    Isoalloxazine derivatives to neutralize biological contaminants 有权
    异环嗪衍生物中和生物污染物

    公开(公告)号：US06268120B1

    公开(公告)日：2001-07-31

    申请号：US09420652

    申请日：1999-10-19

    申请人： Matthew Stewart Platz ,  Raymond Paul Goodrich, Jr.

    发明人： Matthew Stewart Platz ,  Raymond Paul Goodrich, Jr.

    IPC分类号： A01N102

    CPC分类号： A61L2/0076 ,  A61L2/0088 ,  A61L2/10 ,  A61L2202/22 ,  C07D475/14

    摘要： Methods are provided for neutralization of microorganisms in fluids or on surfaces. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an activation-effective amount of a microorganism neutralizer with an isoalloxazine backbone to a fluid and exposing the fluid to a triggering event. Preferred triggering events include light of a suitable wavelength and intensity to activate the microorganism neutralizer or a pH sufficient to activate the microorganism neutralizer. Other fluids, including juices, water and the like, may also be decontaminated by these methods as may surfaces of foods, animal carcasses, wounds, food preparation surfaces and bathing and washing vessel surfaces. Compounds with an isoalloxazine backbone are also provided.

    摘要翻译： 提供了用于中和流体或表面上的微生物的方法。 优选地，流体含有血液或血液制品并且包含生物活性蛋白质。 优选的方法包括以下步骤：将活化有效量的微生物中和剂与异吲嗪骨架加入流体中，并将​​流体暴露于触发事件。 优选的触发事件包括合适的波长和强度的光以激活微生物中和剂或足以活化微生物中和剂的pH。 其他流体，包括果汁，水等也可以通过这些方法，如食品，动物屠体，伤口，食物制备表面和洗浴和洗涤容器表面的表面进行去污染。 还提供了具有异吲哚啉主链的化合物。

    Flavin modifying agent for conductive substrate
    67.
    发明授权
    Flavin modifying agent for conductive substrate 失效
    用于导电基材的黄改性剂

    公开(公告)号：US5149811A

    公开(公告)日：1992-09-22

    申请号：US587470

    申请日：1990-09-21

    申请人： Satoshi Ueyama ,  Satoru Isoda

    发明人： Satoshi Ueyama ,  Satoru Isoda

    IPC分类号： C07D475/14

    CPC分类号： C07D475/14

    摘要： A modifying agent for a conductive substrate which comprises a flavin derivative represented by the formula: ##STR1## wherein R1 represents a hydrogen atom or an acyl groups, R2 and R3 each represent a hydrogen atom or a lower alkyl group having one to four carbon atoms, and R4 represents a thiocyanato group or a mercapto group.

    摘要翻译： 一种导电性基材用改性剂，其特征在于，含有下式所示的黄素衍生物：其中R1表示氢原子或酰基，R2和R3各自表示氢原子或碳原子数1〜4的低级烷基 ，R4表示硫氰酸酯基或巯基。

    Purification of riboflavin
    68.
    发明授权
    Purification of riboflavin 失效
    核黄素的纯化

    公开(公告)号：US4687847A

    公开(公告)日：1987-08-18

    申请号：US743157

    申请日：1985-06-10

    申请人： Johannes Grimmer ,  Hans C. Horn

    发明人： Johannes Grimmer ,  Hans C. Horn

    IPC分类号： C07D475/14

    CPC分类号： C07D475/14

    摘要： Very pure riboflavin (I) is obtained by a process in which the riboflavin is dissolved in dilute aqueous alkali metal hydroxide solution, if necessary the alkaline solution is purified by treatment with active carbon or with a solvent which is insoluble or only slightly soluble in water, the resulting alkaline solution of I is introduced into water which is at 90.degree.-100.degree. C. and to which an acid has been added in an amount such that the reaction mixture is brought to a pH of from 6.5 to 0.8, the temperature being maintained at from 40.degree. to 100.degree. C., the reaction mixture is kept at from 90.degree. to 100.degree. C. for from 10 to 80 minutes and cooled, and I is then isolated.

    摘要翻译： 非常纯的核黄素（I）通过将核黄素溶解在稀碱金属氢氧化物水溶液中的方法获得，如果需要，碱性溶液通过用活性炭或不溶于或仅溶于水的溶剂进行纯化 将得到的I溶液引入到90℃-100℃的水中，加入一定量的酸使得反应混合物的pH值为6.5至0.8，温度 保持在40〜100℃，反应混合物在90〜100℃保持10〜80分钟，冷却，然后分离。

    Purification of riboflavin
    69.
    发明授权
    Purification of riboflavin 失效
    核黄素的纯化

    公开(公告)号：US4567262A

    公开(公告)日：1986-01-28

    申请号：US561467

    申请日：1983-12-14

    申请人： Johannes Grimmer ,  Hans C. Horn

    发明人： Johannes Grimmer ,  Hans C. Horn

    IPC分类号： C07D475/14

    CPC分类号： C07D475/14

    摘要： An improved process for the purification of crude riboflavin which has been prepared by condensation of an N-(D)-ribityl-2-arylazo-4,5-dimethylaniline and barbituric acid or another N-(D)-ribityl-4,5-dimethyl-aniline derivative with a barbituric acid derivative, by dissolving the crude riboflavin in sulfuric acid or phosphoric acid which has been diluted with water and oxidizing the impurities by treating the solution with hydrogen peroxide, or by dissolving the riboflavin in dilute nitric acid at elevated temperature and then isolating the pure riboflavin by precipitation with water, wherein the mineral acid solution of the riboflavin and the oxidizing agent or the solution of the riboflavin in 20 to 70% strength by weight nitric acid is heated extremely rapidly to a temperature at which the solution clearly changes color from greenish to yellow-orange, the solution is kept at this temperature for from 1 to 50, seconds and the oxidation reaction is then interrupted by addition of water.The best results are achieved in this process if from 20 to 65% strength by weight nitric acid is used simultaneously as the acid and oxidative agent and if, after the change in color, the mineral acid solution, in particular the nitric acid solution, is passed, immediately or after prior interruption of the oxidation reaction by addition of cold water, into hot water at from 90.degree. to 100.degree. C. and the suspension thereby formed is kept at this temperature for about a further 10-30 minutes.

    摘要翻译： 通过N-（D） - 对 - 乙基-2-芳基偶氮-4,5-二甲基苯胺和巴比妥酸或另一种N-（D） - 残基-4,5,5-三氟乙酸缩合制备粗制核黄素的改进方法 通过将粗核黄素溶解在已经用水稀释的硫酸或磷酸中并通过用过氧化氢处理该溶液来氧化杂质，或者将核黄素溶解在稀硝酸中，将其溶于硫酸 升高温度，然后通过用水沉淀分离纯的核黄素，其中核黄素和氧化剂的无机酸溶液或核黄素的浓度为20至70重量％的硝酸的硝酸溶液被极快地加热至 该溶液清楚地将颜色从绿色变为黄橙色，将溶液在该温度下保持1至50秒，然后通过加入水分中断氧化反应 r。 如果将20至65％的重量浓度的硝酸同时用作酸和氧化剂，那么在这个过程中可以获得最好的效果，如果在颜色变化后，无机酸溶液，特别是硝酸溶液是 通过，立即或之后通过加入冷水将氧化反应中断之后，在90℃至100℃的热水中通入，并将由此形成的悬浮液在该温度下再保持10-30分钟。