公开(公告)号：US12128077B2

公开(公告)日：2024-10-29

申请号：US17417654

申请日：2019-08-08

Applicant: Lactobio A/S

Inventor： Charlotte Vedel ,  Ida Blomquist Jorgensen ,  Soren Kjaerulff

IPC: A61K39/02 ,  A61K35/747 ,  A61P31/04 ,  C12N1/20 ,  C12R1/225

CPC classification number: A61K35/747 ,  A61P31/04 ,  C12N1/205 ,  C12R2001/225

Abstract: The present invention relates to a bacterial strain having a genetic homology of at least 95% to one or more of the bacterial strains selected from the group consisting of:



Weissella viridescens LB10G, which is deposited as DSM 32906;
Lactobacillus paracasei LB113R, which is deposited as DSM 32907;
Lactobacillus plantarum LB244R, which is deposited as DSM 32996;
Lactobacillus paracasei LB116R, which is deposited as DSM 32908;
Enterococcus faecium LB276R, which is deposited as DSM 32997;
Lactobacillus plantarum LB316R, which is deposited as DSM 33091;
Leuconostoc mesenteriodes LB341R;
Leuconostoc mesenteriodes LB349R, which is deposited as DSM 33093;
Lactobacillus plantarum LB356R, which is deposited as DSM 33094;
Lactobacillus plantarum LB312R, which is deposited as DSM 33098.

公开(公告)号：US20240342229A1

公开(公告)日：2024-10-17

申请号：US18756561

申请日：2024-06-27

Applicant: Grape King Bio Ltd

Inventor： Chin-Chu CHEN ,  Yen-Lien CHEN ,  Shih-Wei LIN ,  You-Shan TSAI ,  Tzu-Chun LIN ,  Ci-Sian WANG ,  Yu-Hsin HOU ,  Yang-Tzu SHIH ,  Ching-Wen LIN ,  Ya-Jyun CHEN ,  Jia-Lin JIANG ,  Zi-He WU ,  Yen-Po CHEN

IPC: A61K35/747 ,  A61K9/00 ,  A61K9/19 ,  A61K35/00 ,  C12N1/20 ,  C12R1/225 ,  C12R1/24 ,  C12R1/25

CPC classification number: A61K35/747 ,  A61K9/0053 ,  A61K9/19 ,  C12N1/205 ,  A61K2035/115 ,  C12R2001/225 ,  C12R2001/24 ,  C12R2001/25

Abstract: The present disclosure relates to an anti-fatigue Lactobacillus composition. The anti-fatigue Lactobacillus composition, which includes at least one of Lactobacillus brevis GKEX, Lactobacillus plantarum GKK1 and Lactobacillus johnsonii GKJ2 as an active ingredient, administered to a healthy subject for a continuous period of time, can significantly improve fatigue-related biochemical indices and prolong aerobic exercise time to exhaustion, and thus can be used as an active ingredient for preparation of various compositions for anti-fatigue and/or improving athletic ability.

公开(公告)号：US20240325468A1

公开(公告)日：2024-10-03

申请号：US18575198

申请日：2022-07-06

Applicant: LISCURE BIOSCIENCES INC.

Inventor： Hwa Sup CHIN

IPC: A61K35/747 ,  A61P37/06 ,  C12N1/20 ,  C12R1/225

CPC classification number: A61K35/747 ,  A61P37/06 ,  C12N1/205 ,  C12R2001/225

Abstract: The present disclosure relates to a composition containing Lactobacillus sakei or extracellular vesicles derived therefrom. The present disclosure also relates to a novel Lactobacillus sakei LBML6 strain. The Lactobacillus sakei according to the present disclosure is a strain which has inhibitory activity against TNFα and IgG in blood and in which the proportion of tolDC cells and Treg cells is increased, and can be used for various applications such as the prevention, alleviation and/or treatment of autoimmune disease in human or animals as well as intestinal regulation.

公开(公告)号：US20240315951A1

公开(公告)日：2024-09-26

申请号：US18546052

申请日：2022-12-13

Applicant: LG HOUSEHOLD & HEALTH CARE LTD.

Inventor： Haemin JUNG ,  Mirim KIM ,  Fukushi MUNEMITSU ,  Hojong LEE

IPC: A61K8/9728 ,  A61K8/99 ,  A61Q19/08 ,  C12N1/18 ,  C12N1/20 ,  C12R1/11 ,  C12R1/225 ,  C12R1/865

CPC classification number: A61K8/9728 ,  A61K8/99 ,  A61Q19/08 ,  C12N1/185 ,  C12N1/20 ,  C12R2001/11 ,  C12R2001/225 ,  C12R2001/865

Abstract: The present invention relates to a strain selected from the group consisting of Saccharomyces cerevisiae KCTC14779BP, Saccharomyces cerevisiae KCTC14780BP, Lactobacillus fructivorans KCTC14776BP, Bacillus paramycoides KCTC14777BP, and Bacillus megaterium KCTC14778BP; and a cosmetic composition, a quasi-drug composition, or a food composition comprising any one or more selected from the group consisting of the strain, a culture of the strain, a fermented product of the strain, and a fraction of the culture or fermented product.
Since the Saccharomyces cerevisiae, Lactobacillus fructivorans, Bacillus paramycoides or Bacillus megaterium strain, a culture of the strain, a fermented product of the strain, or a fraction of the culture or fermented product has excellent effects of improving skin and soothing sensitive skin, it can be widely used as cosmetic compositions, quasi-drug compositions, and food compositions for skin improvement. Accordingly, various industrial applications such as cosmetics, quasi-drugs, and foods can be expected.

公开(公告)号：US20240269200A1

公开(公告)日：2024-08-15

申请号：US18032893

申请日：2021-10-14

Applicant: LG HOUSEHOLD & HEALTH CARE LTD.

Inventor： Young-Ok KIM ,  Dong-Gyun KIM ,  Bong Seok KIM ,  Bo-Hye NAM ,  Hee Jeong KONG ,  Seung Jin HWANG ,  Byung Hyun KIM ,  Mu hyun JIN

IPC: A61K35/747 ,  A01N63/20 ,  A01P1/00 ,  A23K10/18 ,  A23K50/80 ,  A61K8/99 ,  A61P31/04 ,  A61Q19/00 ,  A61Q19/08 ,  C12N1/20 ,  C12R1/225

CPC classification number: A61K35/747 ,  A01N63/20 ,  A01P1/00 ,  A23K10/18 ,  A23K50/80 ,  A61K8/99 ,  A61P31/04 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/08 ,  C12N1/20 ,  C12R2001/225

Abstract: The present invention provides a novel Lactobacillus sp. strain, which has high antibacterial activity against various pathogenic bacteria, including bacteria associated with fish diseases and dental cavities, inhibits the production of melanin and promotes the synthesis of collagen, and thus can be utilized as a material for a variety of foods and medicines, and the use thereof.

公开(公告)号：US12037627B2

公开(公告)日：2024-07-16

申请号：US17364632

申请日：2021-06-30

Applicant: CHINA NATIONAL RESEARCH INSTITUTE OF FOOD & FERMENTATION INDUSTRIES CO., LTD.

Inventor： Muyi Cai ,  Ruizeng Gu ,  Jun Lu ,  Kong Ling ,  Lu Lu ,  Ming Zhou ,  Xinyue Cui ,  Xingchang Pan ,  Zhe Dong ,  Yong Ma ,  Yaguang Xu ,  Yongqing Ma ,  Liang Chen ,  Ying Wei ,  Haixin Zhang ,  Yan Liu ,  Kelu Cao ,  Jing Wang ,  Guoming Li ,  Yuchen Wang ,  Yuqing Wang ,  Yuan Bi ,  Xiuyuan Qin

IPC: C12P7/56 ,  C12N1/20 ,  C12P7/46 ,  C12P7/48 ,  C12P7/52 ,  C12P7/54 ,  C12R1/225

CPC classification number: C12P7/56 ,  C12N1/205 ,  C12P7/46 ,  C12P7/48 ,  C12P7/52 ,  C12P7/54 ,  C12R2001/225

Abstract: A Lactobacillus paracasei and uses thereof. The Lactobacillus paracasei has a deposit number of CGMCC No. 14813. The Lactobacillus paracasei can be used for increasing the amount of an organic acid in a raw material. The Lactobacillus paracasei can be used for fermenting the raw material, where the raw material can be selected from at least one of fruits, which can increase the content of the organic acid in a fermented product.

公开(公告)号：US12012589B2

公开(公告)日：2024-06-18

申请号：US17561030

申请日：2021-12-23

Applicant: GenMont Biotech Incorporation

Inventor： Wan-Hua Tsai ,  Wen-Ling Yeh ,  Chia-Lin Wu ,  Chih-Ho Lai ,  Yao-Tsung Yeh ,  Cheng-Hsieh Huang

IPC: C12N1/20 ,  A61K35/00 ,  A61P25/22 ,  C12R1/225 ,  C12R1/23 ,  C12R1/25

CPC classification number: C12N1/205 ,  A61K35/00 ,  A61P25/22 ,  A61K2035/115 ,  C12R2001/225 ,  C12R2001/23 ,  C12R2001/25

Abstract: The present invention provides a Lactobacillus composition and a use thereof for improving anxiety caused by antibiotics, wherein the Lactobacillus composition comprises Lactobacillus plantarum GMNL-141, Lactobacillus rhamnosus GM-020, Lactobacillus acidophilus GMNL-185, or a combination thereof. The Lactobacillus composition can effectively improve imbalance of an individual's intestinal flora caused by antibiotics to help stabilize and increase species richness and increase the synthesis of mood-stabilizing compounds, including flavonoids, flavonols, isoquinoline alkaloids, niacinamide, nicotinamide, and short-chain fatty acids in intestine, and thus effectively improve antibiotic-induced with anxiety disorders.

公开(公告)号：US20240172780A1

公开(公告)日：2024-05-30

申请号：US18283358

申请日：2022-03-10

Applicant: Asahi Group Holdings, Ltd.

Inventor： Hirosuke SUGAHARA ,  Sayaka NAGAOSA ,  Keitaro NAGAYAMA

IPC: A23L7/104 ,  C12N1/20 ,  C12R1/225

CPC classification number: A23L7/104 ,  C12N1/20 ,  C12R2001/225

Abstract: Provided is a method for producing a plant-based milk-fermented liquid having reduced bezaldehyde. The method comprising bringing a plant-based milk into contact with a lactic acid bacterium/bacteria including at least one selected from the group consisting of Lactobacillus fermentum, Lactobacillus reuteri, Lactobacillus oris, and Lactobacillus mucosae.

公开(公告)号：US20240167066A1

公开(公告)日：2024-05-23

申请号：US18283610

申请日：2022-03-24

Applicant: DAICEL CORPORATION

Inventor： Akira OTANI ,  Hiroaki YAMAMOTO ,  Kazuya MITSUHASHI ,  Takafumi MITACHI ,  Satoru FUKIYA ,  Atsushi YOKOTA

IPC: C12P17/06 ,  C12N1/20 ,  C12N9/06 ,  C12N9/10 ,  C12P7/22 ,  C12P17/12 ,  C12R1/185 ,  C12R1/22 ,  C12R1/225 ,  C12R1/46

CPC classification number: C12P17/06 ,  C12N1/205 ,  C12N9/003 ,  C12N9/1014 ,  C12P7/22 ,  C12P17/12 ,  C12R2001/185 ,  C12R2001/22 ,  C12R2001/225 ,  C12R2001/46 ,  C12Y201/02001

Abstract: An object of the present disclosure is at least to provide a technique for promoting elimination of a methyl group(s) of a methoxy group(s) in causing a microorganism having a demethylation ability of eliminating a methyl group(s) of a methoxy group(s) from a compound with the methoxy group(s) in a side chain(s) to produce a demethylated compound in which a methyl group(s) of a methoxy group(s) has eliminated from a compound with the methoxy group(s) in a side chain(s). The issue is solved by a method for producing a demethylated compound, comprising co-culturing, in a solution containing a compound with a methoxy group(s) in a side chain(s), a microorganism having a demethylation ability of eliminating a methyl group(s) of a methoxy group(s) from a compound with the methoxy group(s) in a side chain(s), and a microorganism having an activity to promote the demethylation, to produce the demethylated compound in which a methyl group(s) of a methoxy group(s) has eliminated from the compound with the methoxy group(s) in the side chain(s).

公开(公告)号：US20240150706A1

公开(公告)日：2024-05-09

申请号：US18264954

申请日：2022-02-10

Applicant: Chr. Hansen A/S

Inventor： Deepak Jain ,  Surender Kumar Dhayal

IPC: C12N1/20 ,  C12N1/04 ,  C12N11/04

CPC classification number: C12N1/205 ,  C12N1/04 ,  C12N11/04 ,  C12R2001/225

Abstract: The present invention relates to microencapsulated microbial cultures with high storage stability and methods for producing these. In particular, the present invention relates to microbial cultures formulated at high ratios of encapsulation matrix material to core material.