公开(公告)号：US20080260847A1

公开(公告)日：2008-10-23

申请号：US10592769

申请日：2004-04-15

Applicant: Steven G. Wright ,  Troy Christensen ,  Thean Yeoh ,  Michael E. Rickey ,  Joyce M. Hotz ,  Rajesh Kumar ,  Henry R. Costantino

Inventor： Steven G. Wright ,  Troy Christensen ,  Thean Yeoh ,  Michael E. Rickey ,  Joyce M. Hotz ,  Rajesh Kumar ,  Henry R. Costantino

IPC: A61K9/14 ,  A61K38/00 ,  A61K38/17 ,  A61K38/26 ,  A61K39/395 ,  A61K38/43

CPC classification number: A61K47/34 ,  A61K9/0002 ,  A61K9/1647 ,  A61K9/1694 ,  A61K9/5089 ,  A61K31/573 ,  A61K38/2278 ,  A61K38/26

Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.

Abstract translation: 本发明涉及用于持续释放生物活性多肽的组合物，以及形成和使用所述组合物用于持续释放生物活性多肽的方法。 本发明的缓释组合物包含分散在其中的生物相容性聚合物，生物活性多肽和糖。

公开(公告)号：US20080240107A1

公开(公告)日：2008-10-02

申请号：US12055019

申请日：2008-03-25

Applicant: Nileshkumar J. Parekh ,  Rajesh Kumar ,  Maksim (Max) Krasnyanskiy ,  Eric Hall

Inventor： Nileshkumar J. Parekh ,  Rajesh Kumar ,  Maksim (Max) Krasnyanskiy ,  Eric Hall

IPC: H04L12/56

CPC classification number: H04L1/1642

Abstract: Systems and methodologies are described that facilitate maintaining consistent radio-link layer protocol (RLP) sequence numbers in the event of an RLP sequence number reset. An offset can be adjusted upon occurrence of the event to reflect a subsequent expected sequence number. The offset can be added to the RLP sequence numbers such that receiving devices and/or higher layer applications can operate without realizing the sequence number reset. Additionally, the offset can be synchronized among base stations to facilitate operability following handoff of the receiving device.

Abstract translation: 描述了在RLP序列号重置的情况下有助于维持一致的无线电链路层协议（RLP）序列号的系统和方法。 发生事件时可以调整偏移量以反映随后的预期序列号。 可以将偏移量添加到RLP序列号，使得接收设备和/或更高层应用可以在不实现序列号重置的情况下操作。 此外，可以在基站之间同步偏移，以便于在接收设备切换之后的可操作性。

公开(公告)号：US20080207919A1

公开(公告)日：2008-08-28

申请号：US11815969

申请日：2006-02-10

Applicant: Bhausaheb Chavhan ,  Arun Kumar Awasthi ,  Richa Aggarwal ,  Rani S. Beena ,  Soumendu Paul ,  Rajesh Kumar Thaper ,  Sushil Kumar Dubey

Inventor： Bhausaheb Chavhan ,  Arun Kumar Awasthi ,  Richa Aggarwal ,  Rani S. Beena ,  Soumendu Paul ,  Rajesh Kumar Thaper ,  Sushil Kumar Dubey

IPC: C07D209/18

CPC classification number: C07D209/10

Abstract: Disclosed herein are novel polymorphic forms of Fluvastatin sodium, wherein said polymorphic forms are designated as JF, JF1, JF2, JF3 and are characterized by their powder X-ray diffraction patterns, Infrared absorption spectrums, thermo gravimetric analysis and differential scanning calorimetry. The processes for preparing said polymorphic forms are also disclosed. The present invention also relates to process for preparing amorphous form of Fluvastatin sodium.

Abstract translation: 本文公开了氟伐他汀钠的新型多晶型物，其中所述多态性形式被指定为J F 1，J 2，J 2， > F3，其特征在于它们的粉末X射线衍射图，红外吸收光谱，热重分析和差示扫描量热法。 还公开了制备所述多晶型物的方法。 本发明还涉及制备氟伐他汀钠无定形形式的方法。

公开(公告)号：US20080172661A1

公开(公告)日：2008-07-17

申请号：US12000645

申请日：2007-12-14

Applicant: Arijit Chatterjee ,  Rajesh Kumar Chaurasia

Inventor： Arijit Chatterjee ,  Rajesh Kumar Chaurasia

IPC: G06F9/45

CPC classification number: G06F8/443 ,  G06F11/3466 ,  G06F11/3476

Abstract: The method, an apparatus, and/or a system of cross-platform architecture for replicating profiling scheme in a computer system are disclosed. In one embodiment, a method for forming profiling information of one computer platform in another computer platform includes generating instrumented code by a code instrumenter using a target platform code. The method further includes generating the profile information that the source platform profiling tools can decipher and utilize using the instrumented code, and generating a profile report by analyzing the generated profile information using the source platform profiling tools in a dynamic binary translator that can be used by the dynamic binary translator (DBT) to generate target platform code. In addition, the method may include translating source platform object code into the target platform code using the DBT.

Abstract translation: 公开了用于在计算机系统中复制分析方案的方法，装置和/或跨平台体系结构系统。 在一个实施例中，用于在另一个计算机平台中形成一个计算机平台的分析信息的方法包括使用目标平台代码由代码工具生成装配的代码。 该方法还包括生成源平台分析工具可以使用所检测的代码来解密和利用的简档信息，以及通过使用动态二进制翻译器中的源平台分析工具分析生成的简档信息来生成简档报告 动态二进制翻译器（DBT）来生成目标平台代码。 另外，该方法可以包括使用DBT将源平台对象代码转换成目标平台代码。

公开(公告)号：US07383529B2

公开(公告)日：2008-06-03

申请号：US11057416

申请日：2005-02-14

Applicant: Rajesh Kumar Gupta ,  Sumit Gupta ,  Nikil Dutt ,  Alexandru Nicolau

Inventor： Rajesh Kumar Gupta ,  Sumit Gupta ,  Nikil Dutt ,  Alexandru Nicolau

IPC: G06F17/50

CPC classification number: G06F17/5045

Abstract: A method for performing high-level synthesis (HLS) of a digital design includes a first phase for performing transformations on a behavioral description of the design, and a second phase for selecting a transformation from a plurality of transformations for transforming the behavioral description. The method further includes a third phase for implementing the transformed behavioral description using lower level primitives, and a fourth phase for generating implementation codes for the design.

Abstract translation: 用于执行数字设计的高级合成（HLS）的方法包括用于对设计的行为描述进行变换的第一阶段和用于从用于变换行为描述的多个变换中选择变换的第二阶段。 该方法还包括用于使用较低级原语实现变换的行为描述的第三阶段，以及用于生成用于设计的实现代码的第四阶段。

公开(公告)号：US20080050447A1

公开(公告)日：2008-02-28

申请号：US11826383

申请日：2007-07-13

Applicant: Michael Rickey ,  J. Ramstack ,  Rajesh Kumar

Inventor： Michael Rickey ,  J. Ramstack ,  Rajesh Kumar

IPC: A61K9/50 ,  A61K38/02 ,  A61P43/00

CPC classification number: A61K38/09 ,  A61K9/1641 ,  A61K9/1647 ,  A61K9/1682 ,  A61K9/1694 ,  A61K9/5089 ,  A61K31/519 ,  B01J8/025 ,  B01J13/08 ,  B01J13/12 ,  B01J13/206 ,  B01J14/00 ,  B01J19/121 ,  B01J19/122 ,  B01J19/2415 ,  B01J2219/0877

Abstract: Methods for preparing microparticles having reduced residual solvent levels. Microparticles are contacted with a non-aqueous washing system to reduce the level of residual solvent in the microparticles. Preferred non-aqueous washing systems include 100% ethanol and a blend of ethanol and heptane. A solvent blend of a hardening solvent and a washing solvent can be used to harden and wash microparticles in a single step, thereby eliminating the need for a post-hardening wash step.

Abstract translation: 制备具有降低的残留溶剂水平的微粒的方法。 微粒与非水洗涤体系接触以降低微粒中残留溶剂的含量。 优选的非水洗涤系统包括100％乙醇和乙醇与庚烷的混合物。 可以使用硬化溶剂和洗涤溶剂的溶剂共混物在一个步骤中硬化和洗涤微粒，从而不需要后硬化洗涤步骤。

公开(公告)号：US07332611B2

公开(公告)日：2008-02-19

申请号：US11382157

申请日：2006-05-08

Applicant: Edward Turos ,  Rajesh Kumar Mishra

Inventor： Edward Turos ,  Rajesh Kumar Mishra

IPC: C07D263/02

CPC classification number: C07D263/26 ,  C07D263/52

Abstract: This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against Staphylococcus spp., including methicillin resistant Staphylcoccus aureus (MRSA), and Bacillus spp., including Bacillus anthracis.

Abstract translation: 本发明描述了N-硫醇化的2-恶唑烷酮作为新类抗细菌剂的发现和合成。 这些化合物可以通过Nd保护和N-亚磺酰化由2-恶唑烷酮合成。 发现这些新物质显示出有效的抗细菌活性，包括对葡萄球菌属的抑菌性，包括耐甲氧西林金黄色葡萄球菌（MRSA）和芽孢杆菌属（Bacillus spp。），包括炭疽芽孢杆菌。

公开(公告)号：US07264548B2

公开(公告)日：2007-09-04

申请号：US11174050

申请日：2005-07-01

Applicant: Makoto Tanaka ,  Toru Akazawa ,  Rajesh Kumar Dixit

Inventor： Makoto Tanaka ,  Toru Akazawa ,  Rajesh Kumar Dixit

IPC: A63F13/00

CPC classification number: A63F13/843 ,  A63F13/02 ,  A63F13/06 ,  A63F13/10 ,  A63F13/23 ,  A63F2300/1025 ,  A63F2300/8088 ,  G06F3/0227

Abstract: In the disclosed invention, correlation information expressing the correlation between a plurality of operation terminal devices and information operable therethrough is generated, and such correlation information is output to the operation terminal devices. Such present invention allows the operators of the operation terminal devices to readily recognize the correlation between the operation terminal devices and information operable therethrough among information handled on an information processing devices.

Abstract translation: 在所公开的发明中，生成表示多个操作终端装置与可操作的信息的相关性的相关信息，并将这些相关信息输出到操作终端装置。 本发明允许操作终端设备的操作者容易地识别操作终端设备之间的相关性和在信息处理设备上处理的信息之间可操作的信息。

公开(公告)号：US20070178179A1

公开(公告)日：2007-08-02

申请号：US11519327

申请日：2006-09-11

Applicant: Vijai Lakshmi ,  Ajet Saxena ,  Rajesh Kumar ,  Raghwendra Pal ,  Satyawan Singh ,  Arvind Srivastava ,  Preeti Tiwari ,  Deepak Raina ,  Anil Rastogi ,  Mahendra Srivastava ,  Ramesh Chandra ,  Anju Puri ,  Ram Raghubir ,  Poonam Gupta ,  Narender Tadigoppula ,  Brijendra Tripathi ,  Sudhir Srivastava

Inventor： Vijai Lakshmi ,  Ajet Saxena ,  Rajesh Kumar ,  Raghwendra Pal ,  Satyawan Singh ,  Arvind Srivastava ,  Preeti Tiwari ,  Deepak Raina ,  Anil Rastogi ,  Mahendra Srivastava ,  Ramesh Chandra ,  Anju Puri ,  Ram Raghubir ,  Poonam Gupta ,  Narender Tadigoppula ,  Brijendra Tripathi ,  Sudhir Srivastava

IPC: A61K36/185

CPC classification number: A61K36/58 ,  C07D493/18

Abstract: A bioactive fraction obtained from Xylocarpus that is useful for the treatment of diabetes and dyslipidemia. This fraction can be provided in a pharmaceutical composition that is useful as antidiabetic and antidyslipidemic agent, or can be used in a method of treating diabetes and dyslipidemia in a subject. Also, a process for the preparation of bioactive fraction from Xylocarpus. Novel isomeric xyloccensins and the preparation of such compounds. Also, pharmaceutical compositions comprising a therapeutically effective amount of such novel isomeric xyloccensins optionally along with one or more pharmaceutically acceptable carriers, additives, lubricant and diluents and the use of such pharmaceutical compositions in a method for treating dyslipidemia.

Abstract translation: 从Xylocarpus得到的可用于治疗糖尿病和血脂异常的生物活性成分。 该级分可以提供在可用作抗糖尿病和抗脂肪代谢剂的药物组合物中，或可用于治疗受试者的糖尿病和血脂异常的方法。 另外，从Xylocarpus制备生物活性成分的方法。 新型异构体的木糖蛋白和这些化合物的制备。 此外，药物组合物包含治疗有效量的这种新型异构的木糖蛋白，任选地与一种或多种药学上可接受的载体，添加剂，润滑剂和稀释剂一起使用，以及这些药物组合物在治疗血脂异常的方法中的用途。

公开(公告)号：US20070150851A1

公开(公告)日：2007-06-28

申请号：US11356578

申请日：2006-02-17

Applicant: Rajesh Kumar ,  Sanjay Kumar Jain

Inventor： Rajesh Kumar ,  Sanjay Kumar Jain

IPC: G06F9/44

CPC classification number: G06F8/36

Abstract: Systems and methods of scalable language infrastructure for electronic system level tools. In accordance with embodiments of the present invention, knowledge about types, functions and the like is encapsulated in a plurality of intelligent components called active component extension modules that are external to the infrastructure. The infrastructure implements a communication mechanism between the clients and these intelligent components, and acts as a common backbone. The infrastructure itself does not maintain any knowledge about any client, types, functions, etc. In accordance with a method embodiment of the present invention, a request is received from a client of a language infrastructure. The request is forwarded from the language infrastructure to an active component extension module. The active component extension module performs a service responsive to the request.

Abstract translation: 用于电子系统级工具的可扩展语言基础设施的系统和方法。 根据本发明的实施例，关于类型，功能等的知识被封装在被称为活动组件扩展模块的多个智能组件中，该组件在基础设施外部。 基础架构实现了客户端和这些智能组件之间的通信机制，并且作为通用骨干网。 基础设施本身并不保持关于任何客户端，类型，功能等的任何知识。根据本发明的方法实施例，从语言基础设施的客户端接收请求。 该请求从语言基础设施转发到活动组件扩展模块。 活动组件扩展模块响应于该请求执行服务。