公开(公告)号：US20240408594A1

公开(公告)日：2024-12-12

申请号：US18697740

申请日：2022-11-11

Applicant: XIAMEN UNIVERSITY ,  XIAMEN INNODX BIOTECH CO., LTD

Inventor： Dongxu ZHANG ,  Runxin GAO ,  Shaolei HUANG ,  Yulin HUANG ,  Guoqiang LIU ,  Jiayu YANG ,  Juntian ZENG ,  Liuwei SONG ,  Shengxiang GE ,  Jun ZHANG ,  Ningshao XIA

IPC: B01L3/00 ,  B01L7/00

Abstract: The present disclosure relates to a microfluidic chip and a microfluidic chip detection system. The microfluidic chip including: a storage member provided with a groove therein, at least two storage chambers being disposed around the groove; a base disposed at one end of the storage member away from the groove, a reaction chamber being disposed on the base; and a valve disposed in the groove, the valve being configured to operatively communicate any one of the at least two storage chambers with the reaction chamber. The present disclosure can lead the solution in any storage chamber to the reaction chamber or lead the solution in the reaction chamber to any storage chamber by operating the valve, so that the solution transfer is realized, the structure is simple and compact, the length of the flow channels can be greatly shortened, and the detection efficiency is improved.

公开(公告)号：US20240328946A1

公开(公告)日：2024-10-03

申请号：US18267586

申请日：2022-10-13

Applicant: Xiamen University

Inventor： Donghui LI ,  Yan ZHANG ,  Ping HUANG ,  Yabin DENG

IPC: G01N21/64

CPC classification number: G01N21/643 ,  G01N2201/06193 ,  G01N2201/127

Abstract: The present disclosure provides a fluorescence analysis method for lithium ion determination using free-base phthalocyanine (FBPc) as a molecular probe, and relates to the technical field of fluorescent probes. The method includes the following steps: adding an alkaline organic medium separately into a plurality of reaction vessels, and adding a phthalocyanine organic solution having a same volume as that of the alkaline organic medium; adding lithium ion organic solutions with increasing concentrations in sequence; diluting an obtained reaction system, allowing to stand to conduct a reaction, scanning a fluorescence spectrum of the reaction system, and determining a relative fluorescence intensity at a fluorescence peak. A determination principle is that in organic media, especially an alkaline organic medium, lithium ions can react with the FBPc to emit strong red fluorescence, and generation of the fluorescence has the remarkable characteristics of ultra-sensitivity and high specificity.

公开(公告)号：US12102086B2

公开(公告)日：2024-10-01

申请号：US18454855

申请日：2023-08-24

Applicant: XIAMEN UNIVERSITY

Inventor： Kejian Wang ,  Manyu Jiang ,  Fangyi Chen

IPC: A61K38/17 ,  A01N37/46 ,  A01P1/00 ,  A01P3/00 ,  A23K20/195 ,  A23K50/80 ,  C07K14/435

CPC classification number: A01N37/46 ,  A01P1/00 ,  A01P3/00 ,  A23K20/195 ,  A23K50/80 ,  A61K38/1767 ,  C07K14/43509

Abstract: An antimicrobial peptide Spampcin56-86from Scylla paramamosain is provided. A molecular formula of the antimicrobial peptide Spampcin56-86 is C154H256N54O33S3, and an amino acid sequence of the antimicrobial peptide Spampcin56-86 is shown in SEQ ID NO: 01.

公开(公告)号：US12077679B2

公开(公告)日：2024-09-03

申请号：US17456499

申请日：2021-11-24

Applicant: FUJIAN SOUTH PEAK FIRE PREVENTION TECHNOLOGY CO., LTD. ,  XIAMEN UNIVERSITY

Inventor： Jianghai Fang ,  Lizong Dai ,  Qingliang Liu ,  Yansong Liu ,  Huanhuan Xu ,  Chun'e Guo

IPC: C09D5/18 ,  C09D5/02 ,  C09D5/08 ,  C09D7/43 ,  C09D7/61 ,  C09D7/65 ,  C09D123/08 ,  C09D131/04

CPC classification number: C09D5/185 ,  C09D5/022 ,  C09D5/084 ,  C09D7/43 ,  C09D7/61 ,  C09D7/65 ,  C09D131/04

Abstract: Disclosed are an intumescent fire-retardant coating with ultra-high corrosion resistance and a preparation method thereof. The fire-retardant coating is composed by water, wetting and dispersing agent, defoaming agent, composite carbon-forming catalyst, composite blowing agent, pentaerythritol, titanium dioxide, Mg(OH)2, mica powder, kaolin, anti-rust pigment, aluminum tripolyphosphate, VAE emulsion, freeze-thaw agent, film-forming aid, and thickener. On the basis of the existing fire-retardant coatings, the present disclosure adds a series of anti-corrosion, heat insulation fillers and salt spray resistance additives to achieve a certain salt spray resistance effect. The fire-retardant coating of the present disclosure has both fire-retardant and anticorrosive functions, does not contain organic solvents, is low in price, has high construction tolerance, and has broad application prospects in the field of intumescent fire-retardant coatings.

公开(公告)号：US20240238910A1

公开(公告)日：2024-07-18

申请号：US18449932

申请日：2023-08-15

Applicant: Xiamen Jissyu Solder Paste Co., Ltd. ,  Xiamen University

Inventor： Xuzhang ZHENG ,  Zhihao Zhang ,  Jixian Xing ,  Guangxin Wang ,  Shiqin Li

IPC: B23K35/02 ,  B22F1/05 ,  B22F1/065 ,  B22F1/145 ,  B22F1/17

CPC classification number: B23K35/025 ,  B22F1/05 ,  B22F1/065 ,  B22F1/145 ,  B22F1/17 ,  B22F2301/10 ,  B22F2301/15 ,  B22F2301/255 ,  B22F2301/30 ,  B22F2304/10 ,  B22F2999/00

Abstract: The present invention relates to a composite metal material and a low-temperature solder paste with high thermal conductivity containing the same. The composite metal material is a Cu core/Ag intermediate layer/Sn shell type metal powder (Cu@Ag@Sn) or a Cu core/Ni intermediate layer/Sn shell type metal powder (Cu@Ni@Sn) with a particle size of 20-60 μm. The low-temperature solder paste with high thermal conductivity is obtained by mixing the composite metal material with an Sn—Bi series alloy powder and a flux paste, can be used for welding of a variety of substrate, and is suitable for welding at a low temperature of lower than 150° C. The composite metal material of the present invention has a simple process, a low cost and high practicability, and poor heat dissipation and other problems of power devices after die bonding caused by low thermal conductivity of current solder pastes on the market are solved.

公开(公告)号：US20240228453A1

公开(公告)日：2024-07-11

申请号：US18544186

申请日：2023-12-18

Applicant: Xiamen University

Inventor： Xing TANG ,  Weizhen XIE ,  Lu LIN ,  Xianhai ZENG ,  Yong SUN ,  Zheng LI ,  Shuliang YANG

IPC: C07D307/68 ,  B01J6/00 ,  B01J23/42 ,  B01J23/44 ,  B01J23/46 ,  B01J27/25 ,  B01J37/00 ,  B01J37/04 ,  B01J37/18

CPC classification number: C07D307/68 ,  B01J6/001 ,  B01J23/42 ,  B01J23/44 ,  B01J23/462 ,  B01J27/25 ,  B01J37/0036 ,  B01J37/04 ,  B01J37/18

Abstract: A catalyst, an application, and a method for preparing 2,5-furanedicarboxylic acid by catalyzing 5-hydroxymethylfurfural in a base-free condition, which include a catalyst having the formula A/MnaBbOx-yVC, wherein A is Pt, Ru, Pd, or Au, B is Co, Ce, Cu, or Ni, a mole ratio of a and b is 1.5-14, and y=0.0-0.4.

公开(公告)号：US11982002B2

公开(公告)日：2024-05-14

申请号：US16641780

申请日：2018-08-17

Applicant: XIAMEN UNIVERSITY

Inventor： Nanfeng Zheng ,  Jian Peng ,  Shuqiang Hao ,  Binghui Wu ,  Xiaoliang Fang

IPC: C23F11/00 ,  C22C9/00 ,  C23F11/12 ,  C23F11/14 ,  C23F11/16

CPC classification number: C23F11/122 ,  C22C9/00 ,  C23F11/16

Abstract: An anticorrosion treatment method for a copper-containing material comprises: carrying out a sealed and pressurized reaction on a copper-containing material and a stabilizer in presence of a polar solvent and any assistant, the stabilizer being a compound capable of providing formates, so that the formates are adsorbed on the surface of the copper-containing material. In the method, formates are modified on the surface of the copper-containing material, accordingly, the oxidation resistance capability and the stability of the copper-containing material can be significantly improved while the electrical conductivity of the copper-containing material is not reduced, and the corrosion resistance of the copper-containing material and especially, the salt and alkali corrosion resistance of the copper-containing material are significantly improved.

公开(公告)号：US20240138406A1

公开(公告)日：2024-05-02

申请号：US18398278

申请日：2023-12-28

Applicant: Xiamen University

Inventor： Kejian WANG ,  Ying ZHOU ,  Fangyi CHEN

IPC: A01N37/46 ,  A01P1/00 ,  A01P3/00 ,  C07K14/435

CPC classification number: A01N37/46 ,  A01P1/00 ,  A01P3/00 ,  C07K14/43509

Abstract: An antimicrobial peptide Scyampcin44-63, a formula of the antimicrobial peptide Scyampcin44-63 is C113H188N30O24S2, and an amino acid sequence of the antimicrobial peptide Scyampcin44-63 is SEQ ID NO: 01 with the C-terminus being amidated.

公开(公告)号：US11952368B2

公开(公告)日：2024-04-09

申请号：US17956727

申请日：2022-09-29

Applicant: XIAMEN UNIVERSITY

Inventor： Haojun Chen ,  Liang Zhao ,  Qin Lin ,  Kaili Fu ,  Yizhen Pang ,  Zhide Guo ,  Jianyang Fang ,  Long Sun ,  Hua Wu

IPC: C07D401/14 ,  A61K51/04

CPC classification number: C07D401/14 ,  A61K51/0482

Abstract: Provided are a fibroblast activation protein inhibitor (FAPI) dimer compound, an FAPI dimer-based positron emission tomography (PET) imaging agent for tumor diagnosis, and a preparation method and use thereof. An amphiphilic polyethylene glycol (PEG) chain and a dimerized structure of FAPI in the FAPI dimer compound with a structure shown in formula I can improve the in vivo kinetic properties of the compound and prolong a residence time of the compound in a tumor, thereby improving the uptake and imaging effects in the tumor. The accurate tumor diagnosis can be achieved by labeling the FAPI dimer compound with a diagnostic nuclide (68Ga), which has promising application prospects in PET imaging for diagnosis and in the preparation of a therapeutic nuclide (such as 177Lu or 90Y)-labeled drug for treating a FAP-α-expressing tumor.

公开(公告)号：US20240045193A1

公开(公告)日：2024-02-08

申请号：US18022839

申请日：2021-07-28

Applicant: XIAMEN UNIVERSITY

Inventor： Hailong Wang ,  Songyuan DING ,  Binbin ZHANG ,  Zhongqun TIAN

IPC: G02B21/04 ,  G02B21/00

CPC classification number: G02B21/04 ,  G02B21/0032 ,  G02B21/0076 ,  G01N21/64

Abstract: An objective lens, an optical imaging device, an optical system, and a test method of the optical system, relating to the field of optical testing. The purpose is to optimize the structure of the objective lens. The objective lens comprises a housing and an optical focusing assembly. The housing comprises a cavity, and the cavity is provided with a first opening and a second opening. The optical focusing assembly is mounted in the cavity, the focal point of the optical focusing assembly is located at the second opening, and the optical focusing assembly is configured to focus light entering the housing from the first opening a to the focal point. The optical focusing assembly in the objective lens focuses light on the basis of one of the reflection principle and the refraction principle.