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143 条记录 (耗时 0.034 秒)

    MULTI-ARMED MACROMONOMERS
    73.
    发明申请
    MULTI-ARMED MACROMONOMERS 失效
    多臂式MACROMONOMERS

    公开(公告)号：US20090192275A1

    公开(公告)日：2009-07-30

    申请号：US12352616

    申请日：2009-01-13

    申请人： Joseph C. Salamone ,  Jay F. Kunzler

    发明人： Joseph C. Salamone ,  Jay F. Kunzler

    IPC分类号： C08G77/38

    CPC分类号： C08G77/38 ,  A61L27/34 ,  C08F290/068 ,  C08G81/00 ,  G02B1/043 ,  C08F220/18 ,  C08F220/54 ,  C08F230/08 ,  C08F226/10 ,  C08L83/04 ,  C08L101/14 ,  C08L33/10 ,  C08L33/26

    摘要： Multi-armed macromonomers containing multiple side chains attached to a siloxy-containing core terminated on each end with one or more first substantially linear polysiloxane radicals having a polymerizable ethylenically unsaturated-containing terminal group, wherein each side chain comprises a second substantially linear polysiloxane radical having a polymerizable ethylenically unsaturated-containing terminal group are disclosed. Biomedical devices such as contact lenses formed from the multi-armed macromonomers are also disclosed.

    摘要翻译： 包含连接到含有甲硅烷氧基的核心的多个侧链的多臂大分子单体，每个末端具有一个或多个具有可聚合烯键式不饱和末端基团的第一基本上线性的聚硅氧烷基团，其中每个侧链包含第二基本上线性的聚硅氧烷基团， 公开了一种可聚合烯键式不饱和的端基。 还公开了由多臂大分子单体形成的隐形眼镜的生物医学装置。

    HIGH WATER CONTENT OPHTHALMIC DEVICES
    74.
    发明申请
    HIGH WATER CONTENT OPHTHALMIC DEVICES 有权
    高水含量眼科设备

    公开(公告)号：US20090191256A1

    公开(公告)日：2009-07-30

    申请号：US12350262

    申请日：2009-01-08

    申请人： Richard I. Blackwell ,  Joseph C. Salamone ,  Jay F. Kunzler

    发明人： Richard I. Blackwell ,  Joseph C. Salamone ,  Jay F. Kunzler

    IPC分类号： A61K9/00 ,  C08L83/00 ,  A61P27/02

    CPC分类号： G02B1/043

    摘要： An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent, wherein the ophthalmic device has an equilibrium water content of at least about 70 weight percent and further wherein the ophthalmic device has an evaporative dehydration barrier layer on the surface thereof. A method for the mitigation of evaporative corneal dehydration employing the high water content ophthalmic device is also disclosed.

    摘要翻译： 公开了一种眼科装置，其是单体混合物的聚合产物，其包含（a）主要量的非含硅氧烷的亲水性单体; （b）疏水单体; 和（c）交联剂，其中所述眼科装置具有至少约70重量％的平衡水含量，并且其中所述眼科装置在其表面上具有蒸发性脱水阻隔层。 还公开了一种使用高含水量眼科装置缓解蒸发角膜脱水的方法。

    High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers
    77.
    发明申请
    High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers 审中-公开
    高折射率，亲水单体和聚合物以及包含这种聚合物的眼科装置

    公开(公告)号：US20080183006A1

    公开(公告)日：2008-07-31

    申请号：US12060322

    申请日：2008-04-01

    申请人： Joseph C. Salamone ,  Jay F. Kunzler ,  Richard M. Ozark

    发明人： Joseph C. Salamone ,  Jay F. Kunzler ,  Richard M. Ozark

    IPC分类号： C07C69/52

    CPC分类号： C08F220/30 ,  C08F220/18 ,  C08F220/54 ,  G02B1/043 ,  C08L33/14

    摘要： A hydrophilic, aromatic-based monomer has an aromatic group substituted with at least one hydrophilic substituent and a reactive functional group. Polymers comprising such a hydrophilic, aromatic-based monomers avoid or reduce the risk of forming vacuoles of absorbed water. Furthermore, such polymers have high refractive index, and, thus, are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.

    摘要翻译： 亲水性芳香族单体具有被至少一个亲水取代基和反应性官能团取代的芳基。 包含这种亲水性芳族基单体的聚合物避免或降低形成吸收水的空泡的风险。 此外，这种聚合物具有高折射率，因此有利地用于制造眼科装置，例如眼内透镜，隐形眼镜，角膜环，角膜嵌体和角膜假体。

    High refractive-index, hydrophilic, arylsiloxy-containing macromonomers and polymers, and ophthalmic devices comprising such polymers
    80.
    发明授权
    High refractive-index, hydrophilic, arylsiloxy-containing macromonomers and polymers, and ophthalmic devices comprising such polymers 失效
    高折射率，亲水性，含芳基甲硅烷氧基的大分子单体和聚合物，以及包含这种聚合物的眼科装置

    公开(公告)号：US07297160B2

    公开(公告)日：2007-11-20

    申请号：US11153674

    申请日：2005-06-15

    申请人： Joseph C. Salamone ,  Jay F. Kunzler ,  Richard M. Ozark

    发明人： Joseph C. Salamone ,  Jay F. Kunzler ,  Richard M. Ozark

    IPC分类号： A61F2/16 ,  C08F30/08

    CPC分类号： C08G77/38 ,  C08G77/20 ,  G02B1/043 ,  Y10S525/937 ,  C08L83/04

    摘要： Hydrophilic, arylsiloxy-containing macromonomers have at least a terminal hydrophilic group attached to an arylsiloxy group. The aryl groups attached to siloxy groups can be substituted with other hydrophilic groups. Polymers comprising such hydrophilic, arylsiloxy-containing macromonomers avoid or reduce the risk of forming vacuoles of absorbed water. Furthermore, such polymers have high refractive index, and, thus, are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.

    摘要翻译： 亲水性，芳基甲硅烷氧基的大分子单体具有至少一个与芳基甲硅烷氧基连接的亲水基团。 连接到甲硅烷氧基的芳基可以被其它亲水基取代。 包含这种亲水的含芳基甲硅烷氧基的大分子单体的聚合物避免或降低形成吸收水的空泡的风险。 此外，这种聚合物具有高折射率，因此有利地用于制造眼科装置，例如眼内透镜，隐形眼镜，角膜环，角膜嵌体和角膜假体。