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71.发明申请公开(公告)号：US20100082223A1
公开(公告)日：2010-04-01
申请号：US12512615
申请日：2009-07-30
CPC分类号： F02D41/3845 , F02D41/009 , F02D41/222 , F02M59/366 , F02M59/367
摘要： There is provided a high pressure fuel pump control system for an internal combustion engine which enables fuel pressure control with high precision without being restricted by the number of cylinders of the internal combustion engine or the number of phase sensor signals and the number of cam noses which vertically drives a plunger of a high pressure fuel pump even when a camshaft phase varies by a variable valve timing mechanism by using the high pressure fuel pump with a solenoid valve. The control system has a means which changes an effective stroke by driving the solenoid valve in the high pressure fuel pump, and has a means which changes the drive timing of the high pressure fuel pump based on a cylinder recognition value of the internal combustion engine with the cam angle detecting means as an origin.
摘要翻译： 提供了一种用于内燃机的高压燃料泵控制系统，其能够高精度地进行燃料压力控制，而不受内燃机的气缸数量或相位传感器信号的数量和凸轮的数量的限制 即使当通过使用具有电磁阀的高压燃料泵，凸轮轴相位由可变气门正时机构变化时，垂直地驱动高压燃料泵的柱塞。 控制系统具有通过驱动高压燃料泵中的电磁阀而改变有效行程的装置，并且具有根据内燃机的气缸识别值改变高压燃料泵的驱动正时的装置， 凸轮角度检测装置作为原点。
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公开(公告)号：US07646125B2
公开(公告)日：2010-01-12
申请号：US11613833
申请日：2006-12-20
申请人： Takashi Okamoto , Takuya Maeda , Makoto Funakubo , Takeshi Tamaki
发明人： Takashi Okamoto , Takuya Maeda , Makoto Funakubo , Takeshi Tamaki
IPC分类号： H02K12/21
摘要： A rotor of an electric motor, including a rotor core having a plurality of magnet-retaining apertures, a plurality of permanent magnets individually received and retained in the magnet-retaining apertures of the rotor core, and a resinous filler filling a gap defined between each magnet-retaining aperture and each permanent magnet and fixing the permanent magnets to the magnet-retaining apertures. The rotor also includes an engaging projection provided in the rotor core, the engaging projection tightly engaged with each of the permanent magnets received in the magnet-retaining apertures and temporarily holding each permanent magnet at a predetermined position in a corresponding magnet-retaining aperture, in an unfinished state of the rotor where the resinous filler is not arranged in the gap.
摘要翻译： 一种电动机的转子，包括具有多个磁体保持孔的转子芯，多个永磁体，其分别容纳并保持在转子芯的磁体保持孔中;以及填充填充每个 磁体保持孔和每个永磁体，并将永磁体固定到磁体保持孔。 转子还包括设置在转子芯中的接合突起，接合突起与容纳在磁体保持孔中的每个永磁体紧密接合，并将每个永磁体暂时保持在相应的磁体保持孔中的预定位置， 转子的未完成状态，其中树脂填料未设置在间隙中。
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73.发明申请METHOD FOR MEASUREMENT OF SARS VIRUS NUCLEOCAPSID PROTEIN, REAGENT KIT FOR THE MEASUREMENT, TEST DEVICE, MONOCLONAL ANTIBODY DIRECTED AGAINST SARS VIRUS NUCLEOCAPSID PROTEIN, AND HYBRIDOMA CAPABLE OF PRODUCING THE MONOCLONAL ANTIBODY 审中-公开用于测量SARS病毒核蛋白质蛋白的方法，用于测量的试剂盒，测试装置，针对SARS病毒核蛋白质蛋白的单克隆抗体和产生单克隆抗体的混合物公开(公告)号：US20090280507A1
公开(公告)日：2009-11-12
申请号：US12090055
申请日：2006-10-11
IPC分类号： G01N33/573 , G01N33/536 , G01N33/543 , C07K16/08 , C12N5/16
CPC分类号： G01N33/56983 , C07K14/005 , C07K16/10 , C12N2770/20022
摘要： The present invention provides a method for measuring SARS virus nucleocapsid protein (SARS-NP) using first and second antibodies both binding specifically to SARS-NP, wherein the first or second antibody is an antibody recognizing an epitope located in a region (Region C) of amino acid 283 to 422 from the N-terminus of the amino acid sequence of SARS-NP.
摘要翻译： 本发明提供了使用特异性结合SARS-NP的第一和第二抗体测定SARS病毒核壳蛋白（SARS-NP）的方法，其中第一或第二抗体是识别位于区域（区域C）中的表位的抗体， 从SARS-NP的氨基酸序列的N末端的氨基酸283至422。
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公开(公告)号：US07418337B2
公开(公告)日：2008-08-26
申请号：US11834951
申请日：2007-08-07
CPC分类号： F02D41/3836 , F02D35/023 , F02D41/3845
摘要： An apparatus for controlling the quantity of fuel injection of injectors in accordance with the fuel pressure in the fuel rail of a direct injection type internal combustion engine, including a fuel injection quantity calculating section for calculating the quantity of fuel injection of the injector, a fuel discharge quantity calculating unit for calculating the quantity of fuel discharged from the high-pressure fuel pump into the fuel rail, and a difference calculating unit for calculating the difference between the quantity of fuel injected out of the injector calculated by the fuel injection quantity calculating section and the quantity of fuel discharged from the high-pressure fuel pump into the fuel rail calculated by the fuel discharge quantity calculating unit, wherein the reference value for controlling the injector is obtained on the basis of the difference and the fuel pressure in the fuel rail at the time of starting fuel injection out of injector, and the injector is controlled depending on the reference value.
摘要翻译： 一种用于根据直喷式内燃机的燃料轨道中的燃料压力来控制喷射器的燃料喷射量的装置，包括用于计算喷射器的燃料喷射量的燃料喷射量计算部，燃料 排出量计算单元，用于计算从高压燃料泵排入燃料轨的燃料量;以及差分计算单元，用于计算由燃料喷射量计算部计算出的喷射器中喷出的燃料量之间的差 以及由燃料排出量计算单元计算出的从高压燃料泵排出到燃料轨道的燃料量，其中，基于燃料轨中的差和燃料压力获得用于控制喷射器的基准值 在启动注射器的燃料喷射时，喷射器被控制 取决于参考值。
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公开(公告)号：US20070106009A1
公开(公告)日：2007-05-10
申请号：US11269652
申请日：2005-11-09
IPC分类号： C08G18/42
CPC分类号： C09D175/04 , C08L2666/16
摘要： A thermosetting water-based ultraviolet cut coating which is excellent in film hardness, heat resistance, water resistance and chemical resistance and is gentle to human body and environment, composed of 5-150 parts by weight of an ultraviolet absorber (B), 3-100 parts by weight of an amino resin (C) and 0.01-20 parts by weight of an adhesion promoter (D) to 100 parts by weight of the solids content of an aqueous urethane resin (A), wherein the solids content concentration of the coating is 5-60% by weight, using water as a dispersion medium or a solvent.
摘要翻译： 一种热固性水性紫外线切割涂膜，其膜硬度，耐热性，耐水性和耐化学性优异，对人体和环境温和，由5-150重量份的紫外线吸收剂（B），3- 将100重量份的氨基树脂（C）和0.01-20重量份的粘合促进剂（D）与100重量份的水性聚氨酯树脂（A）的固体含量相比，其中固体含量浓度 涂层为5-60重量％，使用水作为分散介质或溶剂。
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公开(公告)号：US20070105796A1
公开(公告)日：2007-05-10
申请号：US10563074
申请日：2005-04-28
申请人： Naoya Wada , Takashi Okamoto , Keiji Tanigaki , Hirofumi Doi , Yasuhiro Kikuchi , Kensaku Imai
发明人： Naoya Wada , Takashi Okamoto , Keiji Tanigaki , Hirofumi Doi , Yasuhiro Kikuchi , Kensaku Imai
IPC分类号： A61K48/00
CPC分类号： C12N9/1205
摘要： The present invention provides a method for inhibiting the activation of telomerase and an agent for inhibiting the activation of telomerase, a method for inhibiting telomerase activity and an agent for inhibiting telomerase activity, a method for preventing and/or a method for treating a cancer disease, an agent for preventing and/or an agent for treating a cancer disease, all of which comprises inhibiting the binding of MAPKAPK3 to TERT that is a catalytic subunit of telomerase or inhibiting the phosphorylation of TERT by active MAPKAPK3; a method of identifying a compound that inhibits the binding of MAPKAPK3 to TERT or a compound that inhibits the phosphorylation of TERT by active MAPKAPK3; and a reagent kit.
摘要翻译： 本发明提供抑制端粒酶活化的方法和抑制端粒酶活化的试剂，抑制端粒酶活性的方法和抑制端粒酶活性的方法，预防和/或治疗癌症的方法 ，用于预防和/或治疗癌症疾病的药物，所有这些都包括抑制MAPKAPK3与作为端粒酶催化亚基的TERT的结合或抑制活性MAPKAPK3的TERT磷酸化; 鉴定抑制MAPKAPK3与TERT结合的化合物或抑制活性MAPKAPK3磷酸化TERT的化合物的方法; 和试剂盒。
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公开(公告)号：US07091018B2
公开(公告)日：2006-08-15
申请号：US10297599
申请日：2001-06-12
申请人： Tsutomu Fujiwara , Takashi Okamoto , Masashi Niimi , Hiroyuki Kyushiki , Yasuchika Yamamoto , Atsunori Ueyama
发明人： Tsutomu Fujiwara , Takashi Okamoto , Masashi Niimi , Hiroyuki Kyushiki , Yasuchika Yamamoto , Atsunori Ueyama
CPC分类号： C12N9/1096 , A61K48/00
摘要： The present invention is drawn to a gene comprising a polynucleotide encoding a polypeptide composed of an amino acid sequence represented by SEQ ID NO: 1; a gene expression product produced through expression of the gene; a recombinant expression vector including the gene; a host cell (transformant) harboring the recombinant expression vector; a protein composed of an amino acid having an amino acid sequence represented by SEQ ID NO: 1; a therapeutic or preventive composition for hypoglycemia containing as an active ingredient the above-mentioned gene or protein; and an antibody capable of binding to the protein. Through use of the gene or an expression product thereof of the present invention, it is possible to elucidate the pathology of diabetes and develop drugs for treatment and prevention of diabetes via a new action mechanism.
摘要翻译： 本发明涉及包含编码由SEQ ID NO：1所示的氨基酸序列构成的多肽的多核苷酸的基因; 通过表达基因产生的基因表达产物; 包含该基因的重组表达载体; 携带重组表达载体的宿主细胞（转化体） 由具有SEQ ID NO：1所示的氨基酸序列的氨基酸组成的蛋白质; 含有作为上述基因或蛋白质的活性成分的低血糖的治疗或预防组合物; 和能够结合蛋白质的抗体。 通过使用本发明的基因或其表达产物，可以通过新的作用机制阐明糖尿病的病理学并开发用于治疗和预防糖尿病的药物。
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78.发明授权公开(公告)号：US06887623B2
公开(公告)日：2005-05-03
申请号：US10118309
申请日：2002-04-09
申请人： Hiroyuki Fujimoto , Hiroko Sanda , Takashi Okamoto , Toyoki Fujihara , Masahiro Iyori , Maruo Kamino , Shigeki Matsuta
发明人： Hiroyuki Fujimoto , Hiroko Sanda , Takashi Okamoto , Toyoki Fujihara , Masahiro Iyori , Maruo Kamino , Shigeki Matsuta
摘要： An electrode for a rechargeable lithium battery which includes a current collector and a thin film composed of active material that stores and releases lithium and deposited on the current collector, the electrode being characterized in that the current collector has irregularities on its surface and the thin film has spaces extending in a thickness direction of the thin film and configured to increase their width dimensions toward valleys of the irregularities on the current collector surface.
摘要翻译： 一种用于可再充电锂电池的电极，其包括集电器和由存储和释放锂并沉积在集电器上的活性材料构成的薄膜，该电极的特征在于集电器在其表面上具有不规则性，并且薄膜 具有在薄膜的厚度方向上延伸的空间，并将其宽度尺寸增加到集电体表面上的凹凸的谷部。
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79.发明授权High-pressure fuel pump control device and in-cylinder injection engine control device 有权高压燃油泵控制装置和缸内喷油发动机控制装置公开(公告)号：US06526947B2
公开(公告)日：2003-03-04
申请号：US09746070
申请日：2000-12-26
IPC分类号： F02M3704
CPC分类号： F02D41/3845 , F02D41/062 , F02D2041/389 , F02D2250/31 , F02M37/04
摘要： A high-pressure fuel pump accelerates a rise in fuel pressure from engine start-up to shorten an engine start-up time, reduce an exhaust gas substance and improve or increase an engine output. The high-pressure fuel pump is part of a control device which controls an in-cylinder injection engine having a fuel injection valve, a high-pressure fuel pump, and a crank angle sensor. The high-pressure fuel pump is provided with a plunger for pressurizing the fuel placed in the high-pressure fuel pump, a pump drive cam, and a cam angle sensor. A drive signal setting device outputs drive signals to the high-pressure fuel pump at least two or more times from the time of crank angle sensor signal detection to the determination time of the crank and cam angle sensor phases.
摘要翻译： 高压燃油泵加速发动机启动时燃油压力的上升，缩短发动机起动时间，减少废气物质，提高发动机输出。 高压燃料泵是控制具有燃料喷射阀，高压燃料泵和曲轴转角传感器的缸内喷射发动机的控制装置的一部分。 高压燃料泵设置有用于对放置在高压燃料泵中的燃料加压的柱塞，泵驱动凸轮和凸轮角度传感器。 驱动信号设定装置从曲轴转角传感器信号检测到曲轴和凸轮角度传感器相位的确定时间至少两次以上向高压燃料泵输出驱动信号。
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公开(公告)号：US06268156B1
公开(公告)日：2001-07-31
申请号：US09158936
申请日：1998-09-22
IPC分类号： G01N3353
CPC分类号： A61K31/4164 , G01N33/57446
摘要： The present invention is to a method of treating cancer in patients in need thereof with an effective amount of cimetidine. Cimetidine has been found to inhibit the expression of E-selectin, the ligands of sialyl Lewis X and sialyl Lewis A antigen-bearing cancer cells are incapable of attaching to a vascular wall. The present invention has found that cimetidine inhibits metastasis in patients whose specimens stained strongly for sialyl Lewis X and sialyl Lewis A antigens.
摘要翻译： 本发明是一种在有需要的患者中用有效量的西咪替丁治疗癌症的方法。 已经发现西咪替丁抑制E-选择蛋白的表达，唾液酸基路易斯X和唾液酸路易斯A抗原携带癌细胞的配体不能附着于血管壁。 本发明已经发现西咪替丁在其标本对唾液酸路易斯X和唾液酸路易斯A抗原强烈染色的患者中抑制转移。
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