-
71.发明申请公开(公告)号：US20150359940A1
公开(公告)日：2015-12-17
申请号：US14834971
申请日：2015-08-25
CPC分类号： A61L27/50 , A61L27/24 , A61L27/3604 , A61L27/3633 , A61L27/3808 , A61L27/3826 , A61L2430/02 , A61L2430/06 , A61L2430/26 , A61L2430/28 , A61L2430/30 , A61L2430/32 , A61L2430/34 , C12M21/08 , C12M23/06 , C12M23/34 , C12M25/14 , C12N5/0062 , C12N2533/54
摘要： Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
摘要翻译： 描述了可用于制备用于给予患者的含细胞的移植材料的方法，细胞生长底物和装置。 可以在细胞生长底物中定义管状通道以促进细胞分布到底物中。 还描述了用于制备细胞接种组合物的方法和装置，在施用细胞之前预处理细胞生长底物的方法和装置，以及具有新基底的细胞接种移植物及其用途。
-
公开(公告)号：US20150342738A1
公开(公告)日：2015-12-03
申请号：US14821067
申请日：2015-08-07
申请人： Muffin Incorporated
发明人： Peter S. McKinnis , Neal E. Fearnot
IPC分类号： A61F2/24
CPC分类号： A61F2/2475 , A61F2/01 , A61F2/2415 , A61F2/2436 , A61F2002/016 , A61F2220/0016 , A61F2250/0037
摘要： Among other things, there are disclosed embodiments of a valve implant that in particular examples are implantable within a blood vessel, which include a first set of elongate members, a second set of elongate members, and a hood affixed to the first set of elongate members. The first set of elongate members is resiliently deformable, and their distal ends are flared radially outward. The distal ends of the second set of elongate members are distal to the ends of the first set of elongate members. The hood is affixed to the first set of elongate members, and seals against the interior wall of the blood vessel in an expanded configuration. When blood flows from the proximal to the distal side of the valve implant, it presses on the hood, compressing the first set of elongate members, breaking the seal.
摘要翻译： 除其他之外，公开了一种瓣膜植入物的实施例，其特别地示例是可植入在血管内，其包括第一组细长构件，第二组细长构件和固定到第一组细长构件的罩 。 第一组细长构件可弹性变形，并且其远端径向向外张开。 第二组细长构件的远端远离第一组细长构件的端部。 罩被固定到第一组细长构件上，并以扩展构型密封在血管的内壁上。 当血液从瓣膜植入物的近端到远侧流动时，它压在罩上，压缩第一组细长构件，破坏密封。
-
公开(公告)号：US20150094595A1
公开(公告)日：2015-04-02
申请号：US14501746
申请日：2014-09-30
申请人： Muffin Incorporated
CPC分类号： A61B8/0891 , A61B1/018 , A61B8/12 , A61B8/445 , A61B8/4461
摘要： Disclosed are embodiments of devices and methods for imaging the inside of a body part, such as a blood vessel. In particular embodiments, a catheter has a chamber within which is a transducer. A wire guide channel extends throughout the length of the catheter. The transducer is rotatable around the wire guide channel.
摘要翻译： 公开了用于对诸如血管的身体部位的内部进行成像的装置和方法的实施例。 在具体实施例中，导管具有腔室，换能器内部。 导丝通道延伸穿过导管的整个长度。 传感器可围绕导线通道旋转。
-
公开(公告)号：US20140172008A1
公开(公告)日：2014-06-19
申请号：US14086219
申请日：2013-11-21
申请人： Muffin Incorporated
发明人： Peter S. McKinnis , Neal E. Fearnot
CPC分类号： A61B17/50 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/005 , A61F2230/0067 , A61F2250/0093
摘要： A retrieval apparatus for removing an intravascular filter from a body vessel of a patient includes an outer sheath defining an outer lumen, an inner sheath defining an inner lumen wherein the inner sheath is positioned within the outer lumen, a retrieval member positioned in the inner lumen, an ultrasound transducer positioned on the application side of the retrieval member, a guide wire cannula extending between the outer sheath and the inner sheath, the guide wire cannula including an application side end, and a dilator located at an application side end of the retrieval apparatus, said dilator being coupled to said ultrasound transducer and receiving the application side end of said guide wire cannula.
摘要翻译： 一种用于从患者的身体血管中去除血管内过滤器的检索装置包括限定外腔的外鞘，限定内腔的内护套，其中内护套定位在外腔内;取回构件，定位在内腔 位于所述回收构件的所述施用侧的超声波换能器，在所述外护套和所述内护套之间延伸的导丝套管，所述导丝套管包括施加侧端部，以及位于所述取出件的应用侧端部的扩张器 装置，所述扩张器联接到所述超声换能器并且接收所述导丝套管的施用侧端部。
-
公开(公告)号：US12011151B2
公开(公告)日：2024-06-18
申请号：US17385230
申请日：2021-07-26
申请人： Muffin Incorporated , National Institutes of Health, an Agency of the Department of Health and Human Services
发明人： Shaun Davis Gittard , Gregory James Hardy , John C. Sigmon, Jr. , Jeremy T. Newkirk , William J. Havel , Neal E. Fearnot , Toby Rogers , Kanishka Ratnayaka , Robert L. Lederman
IPC分类号： A61B17/02 , A61B90/00 , A61M25/00 , A61M25/10 , A61B17/00 , A61B17/34 , A61M25/01 , A61M25/06
CPC分类号： A61B17/0218 , A61B90/39 , A61M25/0041 , A61M25/0045 , A61M25/10 , A61B2017/00247 , A61B2017/00557 , A61B2017/00845 , A61B2017/00955 , A61B2017/0225 , A61B2017/0237 , A61B2017/3486 , A61B2090/3925 , A61B2090/3966 , A61M2025/0047 , A61M25/0052 , A61M25/0054 , A61M25/0108 , A61M25/0662 , A61M2025/1079 , A61M2025/1093
摘要： Among other things, there is disclosed structure and methods for maintaining access to a location in the body while reducing or eliminating the potential for pulling an access device (e.g. a catheter) back through an opening. An introducer sheath includes a distal indented portion and a balloon, so that once placed in a desired location through tissue, the balloon can be inflated to anchor the sheath against retraction. In particular embodiments, structure and methods for accessing the pericardial cavity via the right atrial appendage are shown.
-
公开(公告)号：US11261423B2
公开(公告)日：2022-03-01
申请号：US16133157
申请日：2018-09-17
申请人： Muffin Incorporated
发明人： Neal E. Fearnot
摘要： Described are medical products, methods, and cryogenic bags or other containers suitable for storing and/or transporting and/or processing cellular compositions and other related materials. In certain aspects, the contents of such cryogenic bags may be warmed, mixed, and applied to a patient. Medical products described herein find particular use in treating diseased and/or damaged tissue such as in wound repair and/or bone repair. Related methods of manufacture are also described.
-
公开(公告)号：US11213392B2
公开(公告)日：2022-01-04
申请号：US16174779
申请日：2018-10-30
申请人： Muffin Incorporated
发明人： Shaun Davis Gittard , John C. Sigmon, Jr. , Gregory James Hardy , Jeremy T. Newkirk , Neal E. Fearnot , William J. Havel , Rita Hadley , Yun Zhou
摘要： Among other things, there are disclosed embodiments of belts or bands that can be used in treatments for tricuspid valve regurgitation. In some embodiments, such belts may be heat-set in a particular configuration to effectively decrease tricuspid annulus when deployed around the atrioventricular groove. Embodiments include one or more tensioning sutures for applying cinching or tightening to belts when deployed, and structure for effectively distributing force during such tightening.
-
公开(公告)号：US11077231B2
公开(公告)日：2021-08-03
申请号：US14834971
申请日：2015-08-25
摘要： Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
-
公开(公告)号：US20200147354A1
公开(公告)日：2020-05-14
申请号：US16742061
申请日：2020-01-14
申请人： Muffin Incorporated
发明人： Frank J. Fischer, JR. , James R. Randolph , Neal E. Fearnot , Jimmy L. Taylor, JR. , Gary B. Shirley
摘要： Described in one aspect is a multi-pressure monitoring system for cell or other therapy includes a first catheter having a first lumen for accepting a treatment device, a second lumen for inflating a balloon, a pressure sensor for monitoring fluid pressure within the first lumen, and a flow restrictor such as a hemostasis valve for limiting the exchange of fluids into and out of the first lumen while treatment devices are present or exchanged in the first lumen. Also disclosed is a method of using the first catheter with a first pressure monitor coupled to the first pressure sensor along with a second catheter attached to a second pressure sensor coupled to a second pressure monitor. The second catheter is positioned within the first lumen of the first catheter during treatment operations and the first and second pressure monitors are used to verify proper pressures throughout the procedure. Described also are novel methods, systems, and catheters for delivering flowable therapeutic substances, such as viable cellular preparations, to patients.
-
公开(公告)号：US10595823B2
公开(公告)日：2020-03-24
申请号：US14211885
申请日：2014-03-14
申请人： Muffin Incorporated
发明人： Peter S. McKinnis , Yun Zhou , Sarah Robbins , Neal E. Fearnot
摘要： There are disclosed embodiments of devices and methods for imaging the inside of a body part, particularly a blood vessel. In particular embodiments, a catheter has a tip chamber, within which is an ultrasound transducer mounted on a pivot mechanism, a motor for turning the transducer, and an implement for pivoting the transducer. Examples of such an implement are a linear motor, a shaft or filament, and the pivot mechanism may be biased to return to a base position when the implement is not pivoting the transducer. In other embodiments, a mirror reflecting ultrasound signals from the transducer may be rotated and/or pivoted, using similar mechanisms.
-
-
-
-
-
-
-
-
-
搜索结果
93 条记录 (耗时 0.018 秒)
