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97 条记录 (耗时 0.051 秒)

    Methods and systems for performing superheated reactions in microscale fluidic systems
    72.
    发明授权
    Methods and systems for performing superheated reactions in microscale fluidic systems 失效
    在微量流体系统中进行过热反应的方法和系统

    公开(公告)号：US06420143B1

    公开(公告)日：2002-07-16

    申请号：US09023693

    申请日：1998-02-13

    申请人： Anne R. Kopf-Sill

    发明人： Anne R. Kopf-Sill

    IPC分类号： C12P1934

    CPC分类号： C12P19/34

    摘要： The present invention is generally directed to methods and systems for performing chemical and biochemical reactions at superheated temperatures by carrying out the reactions in microscale fluidic channels. Also provided are applications of these methods and systems, as well as ancillary systems for use with these methods and systems in monitoring and controlling the performance of the methods of the invention.

    摘要翻译： 本发明一般涉及通过在微流体通道中进行反应来在过热温度下进行化学和生化反应的方法和系统。 还提供了这些方法和系统的应用，以及用于监测和控制本发明的方法的性能的这些方法和系统的辅助系统。

    DEVICES AND METHODS FOR DIAGNOSING, PROGNOSING, OR THERANOSING A CONDITION BY ENRICHING RARE CELLS
    75.
    发明申请
    DEVICES AND METHODS FOR DIAGNOSING, PROGNOSING, OR THERANOSING A CONDITION BY ENRICHING RARE CELLS 审中-公开
    用于通过增加稀有细胞来诊断，预处理或治疗条件的装置和方法

    公开(公告)号：US20140017776A1

    公开(公告)日：2014-01-16

    申请号：US13906206

    申请日：2013-05-30

    申请人： Anne R. Kopf-Sill

    发明人： Anne R. Kopf-Sill

    IPC分类号： G01N1/31

    CPC分类号： G01N33/57488 ,  C12Q1/6883 ,  C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/156 ,  G01N1/31 ,  G01N33/5091 ,  G01N33/57484 ,  G01N33/57492 ,  G01N2333/705 ,  G01N2333/71 ,  G01N2333/912 ,  G01N2333/96433

    摘要： The invention encompasses methods and devices for diagnosing, theranosing, or prognosing a condition in a patient by enriching a sample in rare cells. The devices can be a microfluidic device comprising an array of obstacles and one or more binding moieties. The devices and methods can allow for enrichment of cells based on size and affinity, recovery of cells in locations on the microfluidic device, release of cells from the microfluidic device, flow of sample through the microfluidic device, and retention of rare cells from a sample obtained from a patient having a condition.

    摘要翻译： 本发明包括通过在罕见细胞中富集样品来诊断，鉴别或预测病人状况的方法和装置。 装置可以是包含障碍物阵列和一个或多个结合部分的微流体装置。 装置和方法可以允许基于大小和亲和力富集细胞，在微流体装置上的位置回收细胞，从微流体装置释放细胞，通过微流体装置的样品流，以及从样品中保留稀有细胞 从具有病症的患者获得。

    Modified siphons for improving metering precision
    77.
    发明授权
    Modified siphons for improving metering precision 有权
    改进的虹吸管，以提高计量精度

    公开(公告)号：US06752961B2

    公开(公告)日：2004-06-22

    申请号：US09834300

    申请日：2001-04-12

    申请人： Anne R. Kopf-Sill ,  Carol T. Schembri

    发明人： Anne R. Kopf-Sill ,  Carol T. Schembri

    IPC分类号： G01N930

    CPC分类号： B01L3/502738 ,  B01L2300/0806 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/0409 ,  G01N21/07 ,  Y10T436/111666 ,  Y10T436/25375 ,  Y10T436/2575

    摘要： The present invention provides centrifugal rotors for delivering a premeasured volume of liquid to a chamber in the rotor. In particular the rotors comprise siphons for delivering a premeasured volume of liquid between a first and a second chamber in the rotor. The siphons of the invention are designed such that the inlet of the siphon on the first chamber is radially outward of the siphon outlet on the second chamber. The first chamber is emptied to a level equivalent to the radial position of the siphon outlet.

    摘要翻译： 本发明提供了用于将预先测量的体积的液体输送到转子中的室的离心转子。 特别地，转子包括用于在转子中的第一和第二室之间递送预先测量的液体体积的虹吸管。 本发明的虹吸设计成使得第一室上的虹吸入口在第二室上的虹吸出口的径向外侧。 第一个室被排空到与虹吸出口的径向位置相当的水平。