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    Microchannel system for fluid delivery
    6.
    发明授权
    Microchannel system for fluid delivery 失效
    用于流体输送的微通道系统

    公开(公告)号：US5992769A

    公开(公告)日：1999-11-30

    申请号：US489069

    申请日：1995-06-09

    Applicant: Kensall D. Wise ,  Jingkuang Chen

    Inventor： Kensall D. Wise ,  Jingkuang Chen

    IPC: A61M5/32 ,  B41J2/16 ,  B05B1/14 ,  B41J2/05

    CPC classification number: B41J2/1628 ,  A61M5/32 ,  B41J2/1601 ,  B41J2/1631 ,  A61M5/3291 ,  Y10S239/19 ,  Y10S366/01

    Abstract: Microchannels for conducting and expelling a fluid are embedded in a surface of a silicon substrate. A channel seal is made of plural cross structures formed integrally with the silicon substrate. The cross structures are arranged sequentially over each channel, each cross structure having a chevron shape. The microchannel is sealed by oxidizing at least partially the cross structures, whereby the spaces therebetween are filled. A dielectric seal which overlies the thermally oxidized cross structures forms a complete seal and a substantially planar top surface to the silicon substrate. The dielectric seal is formed of a low pressure chemical vapor deposition (LPCVD) dielectric layer. The channel is useful in the production of an ink jet print head, and has a polysilicon heater overlying the dielectric seal. A current passing through the heater causes a corresponding increase in the temperature of the ink in the microchannel, causing same to be expelled therefreom. After expulsion of the fluid, the microchannel is refilled by capillary action. Control circuitry, including bonding pads and sensors, can be formed integrally on the silicon substrate. In drug or chemical delivery systems, sensors and/or stimulation circuitry for sensing or inducing neural and other response can be formed directly in the silicon substrate which contains the microchannel. The sensor is disposed in close proximity to the chemical distribution nozzle, facilitating neural and other studies. Microvalve arrangements can be formed with the microchannel, controlled by the on-chip circuitry.

    Abstract translation: 用于导电和排出流体的微通道嵌入在硅衬底的表面中。 通道密封由与硅基板一体形成的多个横向结构构成。 交叉结构依次布置在每个通道上，每个交叉结构具有人字形。 通过至少部分地氧化交叉结构来密封微通道，由此填充它们之间的空间。 覆盖在热氧化交叉结构上的电介质密封件形成完整的密封件和基本平坦的顶部表面。 电介质密封由低压化学气相沉积（LPCVD）介电层形成。 该通道在生产喷墨打印头中是有用的，并且具有覆盖在电介质密封件上的多晶硅加热器。 通过加热器的电流导致微通道中的墨水的温度相应增加，从而导致其在那里被排出。 在排出流体之后，通过毛细管作用重新填充微通道。 包括接合焊盘和传感器的控制电路可以一体地形成在硅衬底上。 在药物或化学物质输送系统中，用于感测或诱导神经和其他反应的传感器和/或刺激电路可以直接形成在包含微通道的硅衬底中。 传感器靠近化学分配喷嘴设置，便于神经和其他研究。 可以利用芯片电路控制的微通道形成微型阀组件。

    Fluid flow conducting module
    10.
    发明申请
    Fluid flow conducting module 失效
    流体流动传导模块

    公开(公告)号：US20060237069A1

    公开(公告)日：2006-10-26

    申请号：US11112467

    申请日：2005-04-23

    Applicant: Jyh-Jain Chen ,  Jhy-Wen Wu

    Inventor： Jyh-Jain Chen ,  Jhy-Wen Wu

    IPC: F16K11/20

    CPC classification number: F15D1/14 ,  B01F5/061 ,  B01F5/0646 ,  B01F5/0654 ,  B01F13/0059 ,  B01F2005/0621 ,  B01J2219/00858 ,  B01J2219/00905 ,  B01L3/5027 ,  B01L2200/0636 ,  F16K99/0001 ,  F16K99/0021 ,  F16K99/0028 ,  F16K99/0057 ,  F16K2099/0084 ,  Y10S366/01 ,  Y10T137/87249 ,  Y10T137/87281

    Abstract: Disclosed is a fluid flow conducting module comprising two or more inlets, one or more outlets, and a chamber that has a first and second blocks therein. Further, the chamber has a gradually wider section in the middle, and two convergent ends. One convergent end is connected to the inlets, and the other convergent end is connected to the outlets. The first block has an acute angle in the front, and is placed close to the first convergent end and the inlets. The second block has a convex surface in the front, and is placed close to the second convergent end. The fluids are injected into the chamber through the inlets, flow through the chamber, and conducted towards one or more outlets for further collection and analysis. This fluid flow conducting module has a wide range of flow speed and a simple structure. It can be used in a wide range of applications, such as cell culture, cell reaction to medicine or bio-chemical detection.

    Abstract translation: 公开了一种包括两个或更多个入口，一个或多个出口和在其中具有第一和第二块的室的流体流动传导模块。 此外，室在中间具有逐渐变宽的部分，并且两个收敛端部。 一个收敛端连接到入口，另一个收敛端连接到出口。 第一块在前部具有锐角，并且靠近第一收敛端和入口放置。 第二块在前部具有凸面，并且靠近第二会聚端放置。 流体通过入口注入到腔室中，流过腔室，并且朝向一个或多个出口传导以进一步收集和分析。 该流体流动传导模块具有宽的流速范围和简单的结构。 它可用于广泛的应用，如细胞培养，细胞对药物的反应或生物化学检测。

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