摘要:
The object of the present invention is to find a pharmaceutical composition and a method for treating cancer that show an excellent antitumor effect. Combinational use of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide and analogues thereof can result in an excellent antitumor effect when combined with a substance having a c-kit kinase-inhibiting activity.
摘要:
A liquid crystal display having a wide viewing angle and easily manufactured. The liquid crystal display comprises an upper substrate and a lower substrate, and a liquid crystal material disposed between the upper substrate and the lower substrate. The liquid crystal display has a conductive protrusion disposed on the surface of the upper substrate opposing to the lower substrate. The conductive protrusion is disposed over a scanning electrode line or a signal electrode line and has the same potential as that of the upper electrode. As another structure, each of pixel electrodes on the lower substrate has a smaller area than that of a common electrode on the upper substrate and is covered by the common electrode, and each of the pixel electrodes comprises an electrode portion having approximately symmetrical shape.
摘要:
An impurity derived from a high-molecular-weight polyethylene glycol compound is removed from a high-molecular-weight polyethylene glycol compound whose total average number of moles of ethylene oxide units added in the molecule is 220 to 4500. In a state where the high-molecular-weight polyethylene glycol compound is dissolved in at least one of water and an organic solvent selected from aromatic hydrocarbon solvents having 8 or less carbon atoms in total and ester compound solvents having 5 or less carbon atoms in total, the water and the organic solvent are mixed. The resulting mixture was separated into an organic layer and an aqueous layer, and the organic layer is separated from the aqueous layer.
摘要:
A cantilever includes: a lever portion; a holder portion supporting the proximal end of the lever portion; a probe portion arranged at the distal end of the lever portion and having a spherical surface to face a sample; and a retaining portion fixed to the distal end of the lever portion and retaining the probe portion to surround a periphery of the probe portion. There is provided a cantilever allowing mounting of a probe portion with little effect in a short time without using any adhesive.
摘要:
A hydraulic pump includes a housing including an inlet port, an outlet port, and a fluid chamber, a shaft fixed to the housing, a rotor including an impeller portion that rotates relative to the shaft, the impeller portion suctioning and discharging a fluid, a fixed portion provided at the housing and made of an aluminum alloy, the fixed portion securing the shaft, a short-circuit portion provided at the shaft and made of a stainless steel having a nitrided layer at a surface, the short-circuit portion being supplied with a protection current from the fixed portion by galvanically making contact with the fixed portion, and a support portion rotatably supporting the rotor and formed by extending from the short-circuit portion, an outer peripheral surface of the support portion being covered with an amorphous carbon film of which a main component is carbon and which includes silicon.
摘要:
Compounds represented by the following general formula: [wherein Ag is an optionally substituted 5- to 14-membered heterocyclic group, etc.; Xg is —O—, —S—, etc.; Yg is an optionally substituted C6-14 aryl group, an optionally substituted 5- to 14-membered heterocyclic group, etc.; and Tg1 is a group represented by the following general formula: (wherein Eg is a single bond or —N(Rg2)—, Rg1 and Rg2 each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, etc. and Zg represents a C1-8 alkyl group, a C3-8 alicyclic hydrocarbon group, a C6-14 aryl group, etc.)], salts thereof or hydrates of the foregoing.
摘要:
An in-cylinder pressure detection device for an internal combustion engine, which is capable of calculating a hysteresis amount properly to thereby detect in-cylinder pressure with high accuracy. The in-cylinder pressure detection device comprises an in-cylinder pressure sensor that detects in-cylinder pressure as a detected in-cylinder pressure. The in-cylinder pressure detection device estimates an in-cylinder pressure generated when combustion is not performed in the cylinder, as a motoring pressure, calculates a hysteresis amount indicative of a difference between the detected in-cylinder pressure and an actual in-cylinder pressure, based on the detected in-cylinder pressure and the motoring pressure obtained during the exhaust stroke of the engine, and corrects the detected in-cylinder pressure based on the calculated hysteresis amount.
摘要:
A modified bio-related substance, wherein at least one poly(alkylene glycol)oxy group represented by the following formula (1) is combined in a molecule: wherein R is a hydrocarbon group having 1 to 24 carbon atoms, OA1 and OA2 are each an oxyalkylene group having 2 to 4 carbon atoms, the groups represented by R are the same or different from each other in one molecule, and the groups represented by OA2 are the same or different from each other in one molecule, n and m are each average number of moles of the oxyalkylene group added, n represents 0 to 1000, and m represents 10 to 1000.