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    Sealing nasal devices for use while sleeping
    71.
    发明授权
    Sealing nasal devices for use while sleeping 有权
    在睡觉时密封使用鼻塞

    公开(公告)号：US08215308B2

    公开(公告)日：2012-07-10

    申请号：US12884140

    申请日：2010-09-16

    申请人： Rajiv Doshi ,  Motohide Hatanaka ,  Robert A. Howard

    发明人： Rajiv Doshi ,  Motohide Hatanaka ,  Robert A. Howard

    IPC分类号： A61M15/08 ,  A62B7/00 ,  A62B18/00

    CPC分类号： A61M16/06 ,  A61M15/002 ,  A61M15/08 ,  A61M15/085 ,  A61M16/0616 ,  A61M16/0683 ,  A61M16/0688 ,  A61M16/0694 ,  A61M16/106 ,  A61M16/1065 ,  A61M16/107 ,  A61M16/20 ,  A61M16/208 ,  A61M2210/0618 ,  A62B23/06

    摘要： Described here are devices for altering the flow of air in a respiratory cavity such as the mouth and nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from “pursed-lip” breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable oral and removable nasal devices are described. Oral and nasal devices that filter inhaled airflow of debris and allergens are also provided. A nasal device that increases patency of the nares is also provided.

    摘要翻译： 这里描述的是用于改变呼吸腔中的空气流动的装置，例如嘴和鼻孔。 这些方法和装置可用于影响患有各种医学疾病的患者的生理学益处，特别是可能受益于“追求唇”呼吸和非侵入性通气（例如COPD，心力衰竭，睡眠呼吸暂停， 和其他医疗障碍。 这些装置通常是可以放置在呼吸腔内或呼吸腔内的可移除装置，以增加对呼吸腔内的气流的抵抗力。 相对于灵感，耐受性可以有选择地增加。 描述了可移除的口腔和可移除的鼻装置。 还提供了过滤吸入的碎屑和过敏原气流的口腔和鼻部装置。 还提供了增加鼻孔通畅性的鼻部装置。

    LAYERED NASAL RESPIRATORY DEVICES
    72.
    发明申请
    LAYERED NASAL RESPIRATORY DEVICES 有权
    层层呼吸装置

    公开(公告)号：US20110290256A1

    公开(公告)日：2011-12-01

    申请号：US13117933

    申请日：2011-05-27

    申请人： Elliot Sather ,  Arthur Ferdinand ,  Michael L. Favet ,  Danny Yu-Youh Lai ,  Rajiv Doshi

    发明人： Elliot Sather ,  Arthur Ferdinand ,  Michael L. Favet ,  Danny Yu-Youh Lai ,  Rajiv Doshi

    IPC分类号： A61M16/00 ,  B32B38/04 ,  B23P11/00

    CPC分类号： A61M16/208 ,  A61F5/08 ,  A61F5/56 ,  A61M16/0605 ,  A61M16/0688 ,  A61M16/0866 ,  A61M2205/0216 ,  A61M2205/0238 ,  A61M2210/0618 ,  Y10T29/49826 ,  Y10T156/1064

    摘要： Described herein are nasal devices, including nasal devices formed in layers having four or fewer layers. In some variations, the nasal devices include a single integrated layer from which the flap of the airflow resistor is formed as well as the base of the holdfast region. The nasal devices may include a single aligner or rim body on the side of the device facing the subject. The aligner may protect the airflow resistor, and may help center or position the nasal device. In some variations, these nasal devices may include a noise-reduction feature. Also described herein are systems, devices and methods for determining if a passive nasal respiratory device having an airflow resistor configured to inhibit exhalation more than inhalation has been worn by a subject, and thereby confirming compliance.

    摘要翻译： 这里描述的是鼻装置，包括以具有四层或更少层的层形成的鼻装置。 在一些变型中，鼻部装置包括形成气流阻力器的翼片的单个整体层以及保持区域的基部。 鼻部装置可以包括在面向对象的装置一侧上的单个对准器或边缘体。 对准器可以保护气流阻力器，并且可以帮助中心或定位鼻部装置。 在一些变型中，这些鼻装置可以包括降噪特征。 本文还描述了用于确定具有被配置为抑制呼吸多于吸入的气流电阻器的被动鼻呼吸装置的系统，装置和方法已被受试者佩戴，从而确认顺应性。

    Methods and devices for improving breathing in patients with pulmonary disease
    73.
    发明授权
    Methods and devices for improving breathing in patients with pulmonary disease 有权
    改善肺部疾病患者呼吸的方法和装置

    公开(公告)号：US07992563B2

    公开(公告)日：2011-08-09

    申请号：US12014060

    申请日：2008-01-14

    申请人： Rajiv Doshi

    发明人： Rajiv Doshi

    IPC分类号： A61M11/00

    CPC分类号： A63B23/18 ,  A61B17/12036 ,  A61B17/12104 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/24 ,  A61F2/24 ,  A61F2002/043 ,  A61M16/0488 ,  A61M16/0493 ,  A61M16/06 ,  A61M16/20 ,  A61M16/208

    摘要： Methods, apparatus, and kits for enhancing breathing in patients suffering from chronic pulmonary obstructive disease are described. The methods and apparatus rely on increasing flow resistance to expiration in a manner which mimics “pursed lip” breathing which has been found to benefit patients suffering from this disease. In a first example, a device is implanted in a trachea or bronchial passage to increase flow resistance, preferably selectively increase resistance to expiration relative to inspiration. In a second embodiment, a mouthpiece is provided, again to increase resistance to expiration, preferably with a lesser increase in flow resistance to inspiration. In a third embodiment, the patient's trachea or bronchial passage is modified by the application of energy in order to partially close the lumen therethrough.

    摘要翻译： 描述了用于增强患有慢性肺动脉阻塞性疾病的患者呼吸的方法，装置和试剂盒。 方法和装置依赖于以模仿“追求唇”呼吸的方式增加流出阻力，已被发现有利于患有这种疾病的患者。 在第一示例中，将装置植入气管或支气管通道中以增加流动阻力，优选地选择性地增加相对于吸气的抵抗力。 在第二个实施例中，提供一个接口件，以再次增加对呼气的阻力，优选地，对吸气的流动阻力的增加较小。 在第三实施例中，通过施加能量来改变患者的气管或支气管通道，以便部分地关闭通过其中的内腔。

    METHODS OF TREATING A SLEEPING SUBJECT
    74.
    发明申请
    METHODS OF TREATING A SLEEPING SUBJECT 有权
    治疗睡眠主体的方法

    公开(公告)号：US20110005529A1

    公开(公告)日：2011-01-13

    申请号：US12885359

    申请日：2010-09-17

    申请人： Rajiv Doshi ,  Motohide Hatanaka ,  Robert A. Howard

    发明人： Rajiv Doshi ,  Motohide Hatanaka ,  Robert A. Howard

    IPC分类号： A61F5/56 ,  A61M16/00

    CPC分类号： A61M16/06 ,  A61M15/002 ,  A61M15/08 ,  A61M15/085 ,  A61M16/0616 ,  A61M16/0683 ,  A61M16/0688 ,  A61M16/0694 ,  A61M16/106 ,  A61M16/1065 ,  A61M16/107 ,  A61M16/20 ,  A61M16/208 ,  A61M2210/0618 ,  A62B23/06

    摘要： Described here are devices for altering the flow of air in a respiratory cavity such as the mouth and nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from “pursed-lip” breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable oral and removable nasal devices are described. Oral and nasal devices that filter inhaled airflow of debris and allergens are also provided. A nasal device that increases patency of the nares is also provided.

    摘要翻译： 这里描述的是用于改变呼吸腔中的空气流动的装置，例如嘴和鼻孔。 这些方法和装置可用于影响患有各种医学疾病的患者的生理学益处，特别是可能受益于“追求唇”呼吸和非侵入性通气（例如COPD，心力衰竭，睡眠呼吸暂停， 和其他医疗障碍。 这些装置通常是可以放置在呼吸腔内或呼吸腔内的可移除装置，以增加对呼吸腔内的气流的抵抗力。 相对于灵感，耐受性可以有选择地增加。 描述了可移除的口腔和可移除的鼻装置。 还提供了过滤吸入的碎屑和过敏原气流的口腔和鼻部装置。 还提供了增加鼻孔通畅性的鼻部装置。

    NASAL DEVICES WITH RESPIRATORY GAS SOURCE
    75.
    发明申请
    NASAL DEVICES WITH RESPIRATORY GAS SOURCE 有权
    具有呼吸气源的NASAL设备

    公开(公告)号：US20110005528A1

    公开(公告)日：2011-01-13

    申请号：US12884151

    申请日：2010-09-16

    申请人： Rajiv Doshi ,  Motohide Hatanaka ,  Robert A. Howard

    发明人： Rajiv Doshi ,  Motohide Hatanaka ,  Robert A. Howard

    IPC分类号： A61M16/00 ,  A61F5/56

    CPC分类号： A61M16/06 ,  A61M15/002 ,  A61M15/08 ,  A61M15/085 ,  A61M16/0616 ,  A61M16/0683 ,  A61M16/0688 ,  A61M16/0694 ,  A61M16/106 ,  A61M16/1065 ,  A61M16/107 ,  A61M16/20 ,  A61M16/208 ,  A61M2210/0618 ,  A62B23/06

    摘要： Described here are devices for altering the flow of air in a respiratory cavity such as the mouth and nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from “pursed-lip” breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable oral and removable nasal devices are described. Oral and nasal devices that filter inhaled airflow of debris and allergens are also provided. A nasal device that increases patency of the nares is also provided.

    摘要翻译： 这里描述的是用于改变呼吸腔中的空气流动的装置，例如嘴和鼻孔。 这些方法和装置可用于影响患有各种医学疾病的患者的生理学益处，特别是可能受益于“追求唇”呼吸和非侵入性通气（例如COPD，心力衰竭，睡眠呼吸暂停， 和其他医疗障碍。 这些装置通常是可以放置在呼吸腔内或呼吸腔内的可移除装置，以增加对呼吸腔内的气流的抵抗力。 相对于灵感，耐受性可以有选择地增加。 描述了可移除的口腔和可移除的鼻装置。 还提供了过滤吸入的碎屑和过敏原气流的口腔和鼻部装置。 还提供了增加鼻孔通畅性的鼻部装置。

    Respiratory devices
    76.
    发明授权
    Respiratory devices 有权
    呼吸装置

    公开(公告)号：US07798148B2

    公开(公告)日：2010-09-21

    申请号：US11298339

    申请日：2005-12-08

    申请人： Rajiv Doshi ,  Motohide Hatanaka ,  Robert A. Howard

    发明人： Rajiv Doshi ,  Motohide Hatanaka ,  Robert A. Howard

    IPC分类号： A61M15/08 ,  A62B7/00 ,  A62B18/00

    CPC分类号： A61M16/06 ,  A61M15/002 ,  A61M15/08 ,  A61M15/085 ,  A61M16/0616 ,  A61M16/0683 ,  A61M16/0688 ,  A61M16/0694 ,  A61M16/106 ,  A61M16/1065 ,  A61M16/107 ,  A61M16/20 ,  A61M16/208 ,  A61M2210/0618 ,  A62B23/06

    摘要： Described here are devices for altering the flow of air in a respiratory cavity such as the mouth and nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from “pursed-lip” breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable oral and removable nasal devices are described. Oral and nasal devices that filter inhaled airflow of debris and allergens are also provided. A nasal device that increases patency of the nares is also provided.

    摘要翻译： 这里描述的是用于改变呼吸腔中的空气流动的装置，例如嘴和鼻孔。 这些方法和装置可用于影响患有各种医学疾病的患者的生理学益处，特别是可能受益于“追求唇”呼吸和非侵入性通气（例如COPD，心力衰竭，睡眠呼吸暂停， 和其他医疗障碍。 这些装置通常是可以放置在呼吸腔内或呼吸腔内的可移除装置，以增加对呼吸腔内的气流的抵抗力。 相对于灵感，耐受性可以有选择地增加。 描述了可移除的口腔和可移除的鼻装置。 还提供了过滤吸入的碎屑和过敏原气流的口腔和鼻部装置。 还提供了增加鼻孔通畅性的鼻部装置。

    CPAP INTERFACE AND BACKUP DEVICES
    79.
    发明申请
    CPAP INTERFACE AND BACKUP DEVICES 审中-公开
    CPAP接口和备份设备

    公开(公告)号：US20090194109A1

    公开(公告)日：2009-08-06

    申请号：US12364264

    申请日：2009-02-02

    申请人： Rajiv Doshi ,  Arthur Ferdinand ,  Elliot Sather ,  Michael L. Favet ,  Danny Yu-Youh Lai ,  Toru Mino

    发明人： Rajiv Doshi ,  Arthur Ferdinand ,  Elliot Sather ,  Michael L. Favet ,  Danny Yu-Youh Lai ,  Toru Mino

    IPC分类号： A61M16/00

    CPC分类号： A61M16/0051 ,  A61M16/0066 ,  A61M16/021 ,  A61M16/0666 ,  A61M16/0683 ,  A61M16/0816 ,  A61M16/0866 ,  A61M16/205 ,  A61M16/208 ,  A61M2205/0216

    摘要： Described herein are combined active PAP/passive EPAP interface devices to transmit positive air pressure from a PAP source to the user, but provide passive EPAP when the PAP source is disabled. These interface device may continue to provide benefit to the user even if the PAP source becomes disconnected or otherwise fails. The interface devices described herein include a passive EPAP airflow resistor configured to provide expiratory positive airway pressure (“EPAP”). These interface devices may also include quick connects and/or disconnects for releasably connecting to the source of pressurized breathable gas, a quick release for disconnecting from the source of pressurized breathable gas, and an adhesive user interface region that connects the device the user's face. Also described are adapter for converting a PAP interface devices into combined active PAP/passive EPAP interface devices, and methods of using these devices.

    摘要翻译： 这里描述的是组合的主动PAP /被动EPAP接口设备以将来自PAP源的正空气压力传送给用户，但是当PAP源被禁用时提供被动EPAP。 即使PAP源变得断开或者其他方式失败，这些接口设备也可以继续为用户提供益处。 本文所述的界面装置包括被配置为提供呼气正气道压力（“EPAP”）的被动EPAP气流阻力器。 这些接口装置还可以包括用于可释放地连接到加压的可呼吸气体源的快速连接和/或断开，用于从加压的可呼吸气体源断开的快速释放装置以及将装置连接到使用者的脸部的粘合剂用户界面区域。 还描述了用于将PAP接口设备转换成组合的主动PAP /被动EPAP接口设备的适配器以及使用这些设备的方法。

    Methods and devices for improving breathing in patients with pulmonary disease
    80.
    发明授权
    Methods and devices for improving breathing in patients with pulmonary disease 有权
    改善肺部疾病患者呼吸的方法和装置

    公开(公告)号：US07334581B2

    公开(公告)日：2008-02-26

    申请号：US10827073

    申请日：2004-04-19

    申请人： Rajiv Doshi

    发明人： Rajiv Doshi

    IPC分类号： A61M11/00

    CPC分类号： A63B23/18 ,  A61B17/12036 ,  A61B17/12104 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/24 ,  A61F2/24 ,  A61F2002/043 ,  A61M16/0488 ,  A61M16/0493 ,  A61M16/06 ,  A61M16/20 ,  A61M16/208

    摘要： Methods, apparatus, and kits for enhancing breathing in patients suffering from chronic pulmonary obstructive disease are described. The methods and apparatus rely on increasing flow resistance to expiration in a manner which mimics “pursed lip” breathing which has been found to benefit patients suffering from this disease. In a first example, a device is implanted in a trachea or bronchial passage to increase flow resistance, preferably selectively increase resistance to expiration relative to inspiration. In a second embodiment, a mouthpiece is provided, again to increase resistance to expiration, preferably with a lesser increase in flow resistance to inspiration. In a third embodiment, the patient's trachea or bronchial passage is modified by the application of energy in order to partially close the lumen therethrough.

    摘要翻译： 描述了用于增强患有慢性肺动脉阻塞性疾病的患者呼吸的方法，装置和试剂盒。 方法和装置依赖于以模仿“追求唇”呼吸的方式增加流出阻力，已被发现有利于患有这种疾病的患者。 在第一示例中，将装置植入气管或支气管通道中以增加流动阻力，优选地选择性地增加相对于吸气的抵抗力。 在第二个实施例中，提供一个接口件，以再次增加对呼气的阻力，优选地，对吸气的流动阻力的增加较小。 在第三实施例中，通过施加能量来改变患者的气管或支气管通道，以便部分地关闭通过其中的内腔。