公开(公告)号：US20050187454A1

公开(公告)日：2005-08-25

申请号：US10931482

申请日：2004-09-01

申请人： Reinhard Gabl ,  Tamara Birkenmaier ,  Bjorn-Oliver Eversmann ,  Peter Fromherz ,  Martin Jenkner ,  Matthias Schreiter ,  Roland Thewes ,  Wolfram Wersing

发明人： Reinhard Gabl ,  Tamara Birkenmaier ,  Bjorn-Oliver Eversmann ,  Peter Fromherz ,  Martin Jenkner ,  Matthias Schreiter ,  Roland Thewes ,  Wolfram Wersing

IPC分类号： C12N5/0793 ,  G01N27/414 ,  G01N33/487 ,  A61B17/24 ,  A61B17/26

CPC分类号： C12N5/0619 ,  G01N33/4833

摘要： Biochip for capacitive stimulation and/or detection of biological tissues. The biochip has a carrier structure, at least one stimulation and/or sensor device, which is arranged in or at the carrier structure, and at least one dielectric layer, one layer area of which is arranged at the stimulation and/or sensor device and the opposite layer area of which forms a stimulation and/or sensor area for capacitive simulation and/or detection of biological tissues, wherein the dielectric layer comprises TiO2.

摘要翻译： 用于电容刺激和/或检测生物组织的生物芯片。 生物芯片具有载体结构，布置在载体结构中或载体结构中的至少一个刺激和/或传感器装置，以及至少一个电介质层，其一个区域布置在刺激和/或传感器装置处， 其相对层区域形成用于电容模拟和/或检测生物组织的刺激和/或传感器区域，其中该介电层包含TiO 2。

公开(公告)号：US20050068046A1

公开(公告)日：2005-03-31

申请号：US10913706

申请日：2004-08-05

申请人： Alexander Frey ,  Christian Paulus ,  Meinrad Schienle ,  Roland Thewes

发明人： Alexander Frey ,  Christian Paulus ,  Meinrad Schienle ,  Roland Thewes

IPC分类号： G01N27/416 ,  G01N27/02 ,  G01N27/327 ,  G01N27/403 ,  G01N37/00 ,  G01R27/26

CPC分类号： G01N27/3276

摘要： Circuit arrangement having a sensor electrode, a first circuit unit, which is electrically coupled to the sensor electrode, and a second circuit unit, which has a first capacitor. The first circuit unit holds an electrical potential of the sensor electrode in a predetermined first reference range around a predetermined electrical desired potential by coupling the first capacitor and the sensor electrode such that there is a matching of their electrical potentials. If the second circuit unit detects the electrical potential of the first capacitor being outside a second reference range, the second circuit unit brings the first capacitor to a first electrical reference potential.

摘要翻译： 具有传感器电极，电耦合到传感器电极的第一电路单元和具有第一电容器的第二电路单元的电路装置。 第一电路单元通过将第一电容器和传感器电极耦合使得存在与它们的电位相匹配的方式，将传感器电极的电位保持在预定的电气期望电位周围的预定的第一参考范围内。 如果第二电路单元检测到第一电容器的电位在第二参考范围之外，则第二电路单元将第一电容器引入第一电参考电位。

公开(公告)号：US06870373B2

公开(公告)日：2005-03-22

申请号：US10236889

申请日：2002-09-06

申请人： Ute Kollmer ,  Stephan Sauter ,  Carsten Linnenbank ,  Roland Thewes

发明人： Ute Kollmer ,  Stephan Sauter ,  Carsten Linnenbank ,  Roland Thewes

IPC分类号： G11C7/06 ,  G11C11/405 ,  G11C11/4091 ,  G01R31/11 ,  G01R27/26

CPC分类号： G11C7/06 ,  G11C11/405 ,  G11C11/4091 ,  G11C2207/063

摘要： A circuit configuration for assessing capacitances in a matrix, which has a number of rows with at least one capacitance in at least one dimension, includes a test arm connected to first electrodes of each of the capacitances to be assessed and by which two different potentials can be applied to the first electrodes, a measurement arm connected to second electrodes of each of the capacitances to be assessed and that has a first measurement path and a second measurement path connected to a common potential. The first measurement path has an instrument for assessing the capacitances and the first and second measurement paths can be connected to the second electrodes. The circuit configuration has a drive device that connects each of the capacitances to be assessed individually to the two different potentials.

摘要翻译： 用于评估在至少一维中具有至少一个电容的行数的矩阵中的电容的电路配置包括连接到要评估的每个电容的第一电极的测试臂，并且两个不同的电位可以被 施加到第一电极，测量臂连接到要评估的每个电容的第二电极，并且具有连接到公共电位的第一测量路径和第二测量路径。 第一测量路径具有用于评估电容的仪器，并且第一和第二测量路径可以连接到第二电极。 电路配置具有驱动装置，其将要被分别评估的每个电容连接到两个不同的电位。

公开(公告)号：US20050017190A1

公开(公告)日：2005-01-27

申请号：US10821803

申请日：2004-04-08

申请人： Bjorn-Oliver Eversmann ,  Martin Jenkner ,  Christian Paulus ,  Roland Thewes

发明人： Bjorn-Oliver Eversmann ,  Martin Jenkner ,  Christian Paulus ,  Roland Thewes

IPC分类号： G01N27/414 ,  G01N33/487 ,  H03F3/45

CPC分类号： H03F3/45188 ,  G01N27/4145 ,  G01N33/4836 ,  H03F2203/45352

摘要： Biosensor circuit arrangement including a substrate, a sensor element formed in or on a surface region of the substrate with a physical parameter, which is coupled to a substance to be examined, the type of coupling having a resistive component, the sensor element having an electrically conductive sensor electrode that is coupled to the substance to be examined, the sensor element having a measuring transistor the gate terminal of which is coupled to the electrically conductive sensor electrode, and the physical parameter being the threshold voltage of the measuring transistor, and a calibration device formed in or on the substrate, the calibration device being set up such that it is used to at least partly compensate for an alteration of the value of the physical parameter of the sensor element.

摘要翻译： 生物传感器电路装置，其包括衬底，形成在衬底的表面区域中或其上的具有物理参数的传感器元件，该物理参数耦合到待检查物质，具有电阻部件的耦合类型，所述传感器元件具有电 导电传感器电极，其耦合到待检查的物质，传感器元件具有测量晶体管，栅极端子耦合到导电传感器电极，物理参数是测量晶体管的阈值电压，并且校准 所述校准装置设置成使得其被用于至少部分地补偿所述传感器元件的物理参数的值的变化。

公开(公告)号：US20120275253A1

公开(公告)日：2012-11-01

申请号：US13456047

申请日：2012-04-25

申请人： Richard Ferrant ,  Roland Thewes

发明人： Richard Ferrant ,  Roland Thewes

IPC分类号： G11C7/08 ,  G11C7/06 ,  G11C7/12

CPC分类号： G11C7/065 ,  G11C11/4091 ,  G11C2207/002

摘要： A differential sense amplifier for sensing data stored in a plurality of memory cells of a memory cell array, including a first CMOS inverter having an output connected to a first bit line and an input connected to a second bit line complementary to the first bit line, and a second CMOS inverter having an output connected to the second bit line and an input connected to the first bit line. Each CMOS inverter includes a pull-up transistor and a pull-down transistor, and the sense amplifier has a pair of pass-gate transistors arranged to connect the first and second bit lines to a first and a second global bit lines. Advantageously, the pass-gate transistors are constituted by the pull-up transistors or the pull-up transistors.

摘要翻译： 一种用于感测存储在存储单元阵列的多个存储单元中的数据的差分读出放大器，包括连接到第一位线的输出的第一CMOS反相器和连接到与第一位线互补的第二位线的输入端， 以及具有连接到第二位线的输出和连接到第一位线的输入的第二CMOS反相器。 每个CMOS反相器包括上拉晶体管和下拉晶体管，并且读出放大器具有一对传输栅晶体管，被布置为将第一和第二位线连接到第一和第二全局位线。 有利的是，栅极晶体管由上拉晶体管或上拉晶体管构成。

公开(公告)号：US20120275252A1

公开(公告)日：2012-11-01

申请号：US13456020

申请日：2012-04-25

申请人： Richard Ferrant ,  Roland Thewes

发明人： Richard Ferrant ,  Roland Thewes

IPC分类号： G11C7/12 ,  G11C7/02

CPC分类号： G11C7/065 ,  G11C7/12 ,  G11C11/4091 ,  G11C11/4094 ,  G11C2211/4016

摘要： A differential sense amplifier for sensing data stored in a plurality of memory cells of a memory cell array, including a first CMOS inverter having an output connected to a first bit line (BL) and an input connected to a second bit line complementary to the first bit line and a second CMOS inverter having an output connected to the second bit line (/BL) and an input connected to the first bit line. Each CMOS inverter includes pull-up and pull-down transistors, wherein the sources of either of the pull-up transistors or the pull-down transistors are electrically coupled and connected to a pull-up voltage source or a pull-down voltage source without an intermediate transistor between the sources of the transistors and the voltage source.

摘要翻译： 一种用于感测存储在存储单元阵列的多个存储单元中的数据的差分读出放大器，包括连接到第一位线（BL）的输出的第一CMOS反相器和连接到与第一位线互补的第二位线的输入端 位线和具有连接到第二位线（/ BL）的输出的第二CMOS反相器和连接到第一位线的输入。 每个CMOS反相器包括上拉和下拉晶体管，其中上拉晶体管或下拉晶体管中的任一个的源极电耦合并连接到上拉电压源或下拉电压源，而没有 在晶体管的源极和电压源之间的中间晶体管。

公开(公告)号：US08262875B2

公开(公告)日：2012-09-11

申请号：US11663078

申请日：2005-09-01

申请人： Christian Paulus ,  Meinrad Schienle ,  Claudio Stagni Degli Esposti ,  Roland Thewes

发明人： Christian Paulus ,  Meinrad Schienle ,  Claudio Stagni Degli Esposti ,  Roland Thewes

IPC分类号： B01J8/20

CPC分类号： G01N27/3276

摘要： A sensor arrangement including a control circuit is disclosed. In at least one embodiment, at least one sensor electrode can be charged and/or discharged therewith and a comparator unit for the comparison of a provided voltage for the at least one electrode with a reference voltage. A duration necessary for the charging/discharging of the at least one sensor electrode is determined, whereby, from the determined duration, it is determined whether a sensor event, in the form of a hybridization between trap molecules and the particles for recording, has occurred.

摘要翻译： 公开了一种包括控制电路的传感器装置。 在至少一个实施例中，可以对至少一个传感器电极进行充电和/或放电，以及用于将所述至少一个电极的提供的电压与参考电压进行比较的比较器单元。 确定至少一个传感器电极的充电/放电所需的持续时间，由此从确定的持续时间确定是否发生陷阱分子和用于记录的颗粒之间的杂交形式的传感器事件 。

公开(公告)号：US07944725B2

公开(公告)日：2011-05-17

申请号：US12125684

申请日：2008-05-22

申请人： Roland Thewes ,  Michael Otto ,  Helmut Schneider

发明人： Roland Thewes ,  Michael Otto ,  Helmut Schneider

IPC分类号： G11C5/06

CPC分类号： G11C11/4094 ,  G11C7/08 ,  G11C11/4091 ,  G11C11/4097 ,  G11C2207/005

摘要： A semiconductor memory has a plurality of read amplifiers to which a pair each of two complementary bit lines is connected, wherein the semiconductor memory includes at least one switching element each for each bit line, by which at least a partial section of the bit line may be electrically decoupled from the read amplifier, and wherein the semiconductor memory controls the first switching element so that the first switching element, when reading out and/or refreshing any memory cell connected to the bit line, temporarily electrically decouples at least the partial section of the bit line from the read amplifier.

摘要翻译： 半导体存储器具有多个读取放大器，其中两个互补位线中的每一个被连接到其上，其中半导体存储器包括用于每个位线的至少一个开关元件，通过该至少一个开关元件，位线的至少部分部分可以 与读取放大器电耦合，并且其中半导体存储器控制第一开关元件，使得第一开关元件在读出和/或刷新连接到位线的任何存储单元时暂时将至少部分部分断电 来自读取放大器的位线。

公开(公告)号：US07914655B2

公开(公告)日：2011-03-29

申请号：US10556731

申请日：2004-05-11

申请人： Alexander Frey ,  Christian Paulus ,  Meinrad Schienle ,  Roland Thewes

发明人： Alexander Frey ,  Christian Paulus ,  Meinrad Schienle ,  Roland Thewes

IPC分类号： G01N27/327 ,  G01R19/12

CPC分类号： G01R19/252 ,  C12Q1/6825 ,  G01N27/3276

摘要： A circuit arrangement, an electrochemical sensor, a sensor arrangement, and a method for processing a current signal provided by a sensor electrode are disclosed. The circuit arrangement includes a sensor electrode, a first circuit unit, electrically coupled to the sensor electrode and a second circuit unit, including a first capacitor, whereby the first circuit arrangement is embodied to hold the electrical potential of the sensor electrode in a given first reference range about a set electrical potential and, when the sensor electrode potential falls outside the first reference range, the first capacitor and the sensor electrode are coupled such that a matching of the electrical potentials is possible. The second circuit unit is embodied such that, when the electrical potential of the first capacitor falls outside a second reference range, this event is detected and the first capacitor brought to a first electrical reference potential.

摘要翻译： 公开了电路装置，电化学传感器，传感器装置和用于处理由传感器电极提供的电流信号的方法。 电路装置包括传感器电极，电耦合到传感器电极的第一电路单元和包括第一电容器的第二电路单元，由此第一电路装置被实施为将传感器电极的电势保持在给定的第一 参考范围关于设定的电位，并且当传感器电极电位落在第一参考范围之外时，第一电容器和传感器电极被耦合，使得电位的匹配是可能的。 实施第二电路单元，使得当第一电容器的电位落在第二参考范围之外时，检测到该事件，并将第一电容器带到第一电参考电位。

公开(公告)号：US07809432B2

公开(公告)日：2010-10-05

申请号：US10964560

申请日：2004-10-12

申请人： Bjorn-Oliver Eversmann ,  Martin Jenkner ,  Christian Paulus ,  Roland Thewes

发明人： Bjorn-Oliver Eversmann ,  Martin Jenkner ,  Christian Paulus ,  Roland Thewes

IPC分类号： A61B5/00

CPC分类号： A61B5/7264 ,  A61B5/04001 ,  A61B5/7203 ,  A61B5/7232 ,  A61B5/7282 ,  A61B2562/0209 ,  A61B2562/046 ,  G06N3/061

摘要： Apparatus for measuring neural network activity with a textured semiconductor substrate. Sensor elements have a respective detection electrode on the substrate surface for detecting neural network signals, and the detected neural signals are a basis for outputting electrical sensor output signals via respective sensor element outputs. Each amplifier element has an input and an output. Each of the sensor elements has associated therewith one of the amplifier elements whose input is connected to the sensor output of the respective sensor element. The amplified sensor output signal is output the amplifier output as an amplifier output signal. An activity evaluator has an input, which is connected to at least one of the amplifier outputs, and an output. The activity evaluation device produces an activity signal, which is a measure of activity of the neural network, based on the amplifier output signal, and outputs the amplifier output signal via the evaluation output.

摘要翻译： 用纹理化半导体衬底测量神经网络活动的装置。 传感器元件在基板表面上具有检测电极，用于检测神经网络信号，检测到的神经信号是经由各个传感器元件输出输出电传感器输出信号的基础。 每个放大器元件都有一个输入和一个输出。 每个传感器元件都具有一个放大器元件，其输入端连接到相应传感器元件的传感器输出端。 放大的传感器输出信号作为放大器输出信号输出放大器输出。 活动评估器具有连接到至少一个放大器输出的输入和输出。 活动评估装置基于放大器输出信号产生作为神经网络的活动度量的活动信号，并通过评估输出输出放大器输出信号。