Anti-tumor protease preparations
    71.
    发明授权
    Anti-tumor protease preparations 失效
    抗肿瘤蛋白酶制剂

    公开(公告)号:US4844897A

    公开(公告)日:1989-07-04

    申请号:US906240

    申请日:1986-09-12

    摘要: Method of treating a tumor in a mammal comprises administering to said mammal an effective anti-tumor amount of proteases originating from microorganisms.Method of treating a tumor in a mammal comprises administering to said mammal an effective anti-tumor amount of a protease originating from a microorganism which protease is chemically modified by one of the following procedures:(a) coupling with a saccharide,(b) introduction of a hydrophobic polymeric group,(c) alteration of electric charge of the protein surface,(d) conjugation with a low molecular weight anti-tumor agent of molecular weight less than 2,000,(e) formation of dimer or oligomer by cross-linking of protease molecules,(f) conjugation with a synthetic polycation,(g) conjugation with a synthetic polyanion, and(h) combination of the above-mentioned procedures.Microorganism protease is chemically modified by one of the following procedures:(a) coupling with a saccharide,(b) introduction of a hydrophobic polymeric group,(c) alteration of electric charge of the protein surface,(d) conjugation with a low molecular weight anti-tumor agent of molecular weight less than 2,000,(e) formation of dimer or oligomer by cross-linking of protease molecules,(f) conjugation with a synthetic polycation,(g) conjugation with a synthetic polyanion, and(h) combination of the above-mentioned procedures.

    摘要翻译: 治疗哺乳动物肿瘤的方法包括向所述哺乳动物施用有效的抗肿瘤量的源于微生物的蛋白酶。 治疗哺乳动物肿瘤的方法包括向所述哺乳动物施用有效的抗肿瘤量的来自微生物的蛋白酶,所述蛋白酶通过以下方法之一进行化学修饰:(a)与糖的偶联,(b)引入 的疏水性聚合物组,(c)蛋白质表面电荷的改变,(d)与分子量小于2,000的低分子量抗肿瘤剂缀合,(e)通过交联形成二聚体或低聚物 的蛋白酶分子,(f)与合成聚阳离子的缀合,(g)与合成聚阴离子的缀合,和(h)上述步骤的组合。 微生物蛋白酶通过以下方法之一进行化学修饰:(a)与糖的偶联,(b)引入疏水聚合基团,(c)改变蛋白质表面的电荷,(d)与低分子 (e)通过蛋白酶分子的交联形成二聚体或寡聚体,(f)与合成聚阳离子的缀合,(g)与合成聚阴离子的缀合,和(h)分子量小于2000的重量抗肿瘤剂, 组合上述程序。

    Process for producing conjugated diene polymers
    72.
    发明授权
    Process for producing conjugated diene polymers 失效
    共轭二烯聚合物的制备方法

    公开(公告)号:US4152504A

    公开(公告)日:1979-05-01

    申请号:US788949

    申请日:1977-04-19

    CPC分类号: C08F36/04

    摘要: A process for producing a conjugated diene polymer, which comprises polymerizing (a) a conjugated diene, (b) two or more conjugated dienes or (c) at least one conjugated diene with a monovinyl aromatic compound, at a temperature of from about 30 to about 100.degree. C in an inert hydrocarbon solvent in the presence of a catalyst composition comprising (i) an alkenyl sodium containing 3 to 8 carbon atoms in the alkenyl moiety and (ii) a sodium alkoxide of a dimethylalkyl carbinol containing 1 to 5 carbon atoms in the alkyl moiety.

    摘要翻译: 一种共轭二烯聚合物的制备方法,其包括在(a)共轭二烯,(b)两种或更多种共轭二烯或(c)至少一种共轭二烯与单乙烯基芳族化合物的情况下聚合(a)约30〜 在惰性烃溶剂中,在催化剂组合物存在下,约100℃,所述催化剂组合物包含(i)烯基部分中含有3-8个碳原子的链烯基钠,和(ii)含有1至5个碳原子的二甲基烷基甲醇钠盐 在烷基部分。

    Internal combustion engine system
    73.
    发明授权
    Internal combustion engine system 有权
    内燃机系统

    公开(公告)号:US09359975B2

    公开(公告)日:2016-06-07

    申请号:US13746748

    申请日:2013-01-22

    摘要: Internal combustion engine system includes an electric supercharger which supercharges sucked air; a throttle valve which adjusts the flow amount of intake air of supercharged air into a cylinder; an EGR path in which a part of exhaust gas exhausted from the exhaust manifold side is recirculated to the intake manifold side; an EGR valve which adjusts the amount of exhaust gas passing through the EGR path; and an internal combustion engine control unit which controls the throttle valve, the EGR valve, and the electric supercharger. This enables to satisfy both performance of the supercharger and fuel consumption of the internal combustion engine without complicating the structure of EGR.

    摘要翻译: 内燃机系统包括对吸入空气进行增压​​的电动增压器; 节气门,其调节增压空气进入气缸的进气量; 从排气歧管侧排出的废气的一部分再循环到进气歧管侧的EGR通路; EGR阀,其调节通过所述EGR通路的排气量; 以及控制节流阀,EGR阀和电动增压器的内燃机控制单元。 这使得能够满足增压器的性能和内燃机的燃料消耗,而不会使EGR的结构复杂化。

    Ink composition for forming clear layer, method of applying the same, and printed article using the same
    74.
    发明授权
    Ink composition for forming clear layer, method of applying the same, and printed article using the same 有权
    用于形成透明层的油墨组合物,其使用方法和使用其的印刷品

    公开(公告)号:US09267047B2

    公开(公告)日:2016-02-23

    申请号:US13581203

    申请日:2010-09-13

    摘要: Disclosed is an ink composition for clear layer formation having excellent adhesion properties on substrates, recording layers, and clear layers, as well as excellent overcoat characteristics and refinishing properties. Further disclosed are a coating method for the ink composition, and a printed article formed using the ink composition. The ink composition for clear layer formation is used for forming at least one clear layer on a substrate, or on a printed article on which a printed coating film is formed on a substrate as a recording layer. The ink composition for clear layer formation is characterised in that: the surface free energy of the substrate is 30-45 (mJ/m2); the surface free energy of the recording layer is 40-50 (mJ/m2); the contact angle of the ink composition to the substrate is 30-65 degrees, the contact angle of the ink composition to the recording layer is 40-55 degrees, and the contact angle of the ink composition to the clear layer is 45-60 degrees.

    摘要翻译: 公开了一种用于透明层形成的油墨组合物,其在基材,记录层和透明层上具有优异的粘合性,以及优异的外涂层特性和修补性。 进一步公开了用于油墨组合物的涂布方法和使用该油墨组合物形成的印刷品。 用于透明层形成的油墨组合物用于在基材上形成至少一个透明层,或在基材上形成印刷涂膜的印刷品上作为记录层。 用于透明层形成的油墨组合物的特征在于:基材的表面自由能为30-45(mJ / m 2); 记录层的表面自由能为40-50(mJ / m2); 油墨组合物与基材的接触角为30-65度,油墨组合物与记录层的接触角为40-55度,油墨组合物与透明层的接触角为45-60度 。

    Motor control device for vehicle
    75.
    发明授权
    Motor control device for vehicle 有权
    汽车电机控制装置

    公开(公告)号:US08841873B2

    公开(公告)日:2014-09-23

    申请号:US13294567

    申请日:2011-11-11

    IPC分类号: H02P6/10 H02P21/05 B60L15/20

    摘要: The motor control device includes: a vehicle control device (1) for generating a first torque command value Tref according to state quantities of the vehicle acquired from various sensors (7); a vehicle-resonance-compensation calculation unit (23) for extracting a frequency component generating a vehicle resonance from torque ripple components detected from an electrical angle ω of a motor for traveling (3) by a vehicle resonance component extraction filter (24), and generating a second torque command value Tcmp as a resonance compensation value for carrying out feedback control for the extracted frequency component; and an adder (20) for generating a torque command value Tref_cmp by subtracting the second torque command value Tcmp from the first torque command value Tref, and the motor (3) is controlled according to the torque command value. With this, it is possible to restrain the resonance of the vehicle caused by the torque ripple of the motor (3).

    摘要翻译: 电动机控制装置包括:车辆控制装置(1),用于根据从各种传感器(7)获取的车辆的状态量产生第一转矩指令值Tref; 车辆谐振补偿计算单元,用于通过车辆谐振分量提取滤波器(24)从用于行驶的电机(3)的电角度ω检测的转矩波动分量中提取产生车辆谐振的频率分量;以及 产生第二转矩指令值Tcmp作为对所提取的频率分量进行反馈控制的谐振补偿值; 和通过从第一转矩指令值Tref中减去第二转矩指令值Tcmp产生转矩指令值Tref_cmp的加法器(20),根据转矩指令值控制电动机(3)。 由此,可以抑制由电动机(3)的转矩波动引起的车辆的共振。

    INTERNAL COMBUSTION ENGINE SYSTEM
    76.
    发明申请
    INTERNAL COMBUSTION ENGINE SYSTEM 有权
    内燃机系统

    公开(公告)号:US20130255251A1

    公开(公告)日:2013-10-03

    申请号:US13746748

    申请日:2013-01-22

    IPC分类号: F02M25/07

    摘要: Internal combustion engine system includes an electric supercharger which supercharges sucked air; a throttle valve which adjusts the flow amount of intake air of supercharged air into a cylinder; an EGR path in which a part of exhaust gas exhausted from the exhaust manifold side is recirculated to the intake manifold side; an EGR valve which adjusts the amount of exhaust gas passing through the EGR path; and an internal combustion engine control unit which controls the throttle valve, the EGR valve, and the electric supercharger. This enables to satisfy both performance of the supercharger and fuel consumption of the internal combustion engine without complicating the structure of EGR.

    摘要翻译: 内燃机系统包括对吸入空气进行增压​​的电动增压器; 节气门,其调节增压空气进入气缸的进气量; 从排气歧管侧排出的废气的一部分再循环到进气歧管侧的EGR通路; EGR阀,其调节通过所述EGR通路的排气量; 以及控制节流阀,EGR阀和电动增压器的内燃机控制单元。 这使得能够满足增压器的性能和内燃机的燃料消耗,而不会使EGR的结构复杂化。

    COPPER COMPOUND-CONTAINING ANTIFOULING COATING COMPOSITION HAVING IMPROVED SLIME RESISTANCE AND STORAGE STABILITY
    79.
    发明申请
    COPPER COMPOUND-CONTAINING ANTIFOULING COATING COMPOSITION HAVING IMPROVED SLIME RESISTANCE AND STORAGE STABILITY 审中-公开
    具有改善耐滑性和储存稳定性的含铜复合防锈涂料组合物

    公开(公告)号:US20100209381A1

    公开(公告)日:2010-08-19

    申请号:US12682195

    申请日:2008-10-23

    申请人: Hideyuki Tanaka

    发明人: Hideyuki Tanaka

    IPC分类号: C09D5/16

    摘要: The present invention provides an antifouling coating composition, which can form an antifouling coating film capable of giving excellent slime resistance and has a property such that the recrystallization of an antifouling agent in a paint is depressed. The antifouling coating composition of the present invention is obtainable by blending a coating film forming resin (A) with as an antifouling agent, an inorganic copper antifouling agent (B) such as copper suboxide, etc and N,N′-dimethyl-N′-tolyl(N-fluorodichloromethylthio)sulfamide (C). The antifouling agent (B) is contained in an amount of preferably 60 to 1000 parts by weight based on 100 parts by weight of the coating film forming resin (A), and the antifouling agent (C) is contained in an amount of preferably 1.4 to 80 parts by weight based on 100 parts by weight of the coating film forming resin (A) and also the antifouling agent (C) is contained in an amount of preferably 0.1 to 100 parts by weight based on 100 parts by weight of the antifouling agent (B).

    摘要翻译: 本发明提供一种防污涂料组合物,其可以形成能够赋予优异的耐粘着性的防污涂膜,并且具有使涂料中的防污剂重结晶受到抑制的性质。 本发明的防污涂料组合物可以通过将涂膜形成树脂(A)作为防污剂,无机铜防污剂(B)如低辛氧化钡等和N,N'-二甲基-N' (N-氟二氯甲硫基)磺酰胺(C)。 防污剂(B)相对于100重量份的成膜树脂(A)为100重量份优选为60〜1000重量份,防污剂(C)的含量优选为1.4 相对于100重量份的成膜树脂(A)100重量份,防污剂(C)的含量相对于100重量份的防污剂优选为0.1〜100重量份,优选为80重量份 代理(B)。