公开(公告)号：US20130338991A1

公开(公告)日：2013-12-19

申请号：US13523492

申请日：2012-06-14

申请人： Qingyu Lin ,  Prabal Kanti Bhattacharya ,  Nan Zhang ,  Zhong Fan

发明人： Qingyu Lin ,  Prabal Kanti Bhattacharya ,  Nan Zhang ,  Zhong Fan

IPC分类号： G06F17/50

CPC分类号： G06F17/5081 ,  G06F17/5009 ,  G06F17/5022 ,  G06F17/5036 ,  G06F17/5045 ,  G06F2217/78 ,  Y02E60/76 ,  Y04S40/22

摘要： A method is provided that comprises a circuit design that includes multiple design blocks; a power intent specification file that defines a power domain within the circuit design and that identifies design instances within the power domain and that defines a control function to selectively transition the defined power domain between multiple respective power supply values; using a digital simulator to simulate operation of the digital representation while using an analog simulator to simulate operation of the analog representation; wherein simulating the digital representation includes transitioning the defined power domain between supply values from among the multiple respective supply values; wherein simulating the analog representation includes periodically storing in a storage location a power supply value currently in use during digital simulation of the digital representation; and wherein simulating the analog representation includes using the stored currently in use power supply value to supply voltage to the analog representation.

摘要翻译： 提供一种包括包括多个设计块的电路设计的方法; 功率意图规范文件，其定义电路设计内的功率域，并且识别功率域内的设计实例，并定义控制功能以选择性地在多个相应电源值之间转换所定义的功率域; 使用数字模拟器来模拟数字表示的操作，同时使用模拟仿真器来模拟模拟表示的操作; 其中模拟所述数字表示包括在所述多个相应电源值中的电源值之间转换所述定义的电源域; 其中模拟所述模拟表示包括在所述数字表示的数字模拟期间周期性地存储在存储位置中当前正在使用的电源值; 并且其中模拟所述模拟表示包括使用所存储的当前使用中的电源值为所述模拟表示提供电压。

公开(公告)号：US08486333B2

公开(公告)日：2013-07-16

申请号：US12321359

申请日：2009-01-16

申请人： Mark Wang ,  Nan Zhang

发明人： Mark Wang ,  Nan Zhang

IPC分类号： A61M1/00

CPC分类号： G01N35/00069 ,  G01N2035/00257 ,  G01N2035/00495 ,  Y10T436/2575

摘要： This invention provides rotors and methods of precisely metering a sample fluid and mixing the sample with a reagent. The rotors have a metering tube of defined volume that fills until sample flow is stopped by surface tension of a meniscus at a capillarity port, while excess sample is stripped from the metering tube inlet by centripetal force of the spinning rotor. By spinning the rotor at a higher speed, a reagent can be forced from a reagent chamber to contact the meniscus, breaking the surface tension and allowing the metered sample to mix with the reagent.

公开(公告)号：US08379213B2

公开(公告)日：2013-02-19

申请号：US12806735

申请日：2010-08-18

申请人： Nan Zhang ,  Pingyi Yan

发明人： Nan Zhang ,  Pingyi Yan

IPC分类号： G01N21/55

CPC分类号： G02B26/101 ,  G01N21/6456

摘要： This invention provides methods of array reading and readers of assay result arrays wherein light can be scanned onto analytical region array members from a light source and/or light can be scanned from array members to a detector. One or more mirrors can have one of more pivotable axes enabling scanning light paths to be established between assay result arrays and other components of an analytical device.

摘要翻译： 本发明提供阵列读取方法和测定结果阵列的读取器，其中光可以从光源扫描到分析区域阵列构件上和/或光可以从阵列构件扫描到检测器。 一个或多个反射镜可以具有更多可枢转轴之一，使得能够在分析结果阵列和分析装置的其它部件之间建立扫描光路。

公开(公告)号：US08369928B2

公开(公告)日：2013-02-05

申请号：US12564635

申请日：2009-09-22

申请人： Roger E. Arseneau ,  James Frank Caruba ,  Michael E. Casey ,  Mark Musrock ,  Nan Zhang

发明人： Roger E. Arseneau ,  James Frank Caruba ,  Michael E. Casey ,  Mark Musrock ,  Nan Zhang

IPC分类号： A61B5/05

CPC分类号： G01T1/1603 ,  A61B6/037 ,  A61B6/5247

摘要： A data processing process and embodiment for optimizing the signal path for multi-modality imaging is described. The embodiment and process optimizes the signal to noise ratio in a positron emission tomography (PET) signal path utilizing scintillation crystals, avalanche photo diodes, and charge sensitive preamplifiers in a dual modality MRI/PET scanner. The dual use of both and analog pole zero circuit and a digital filter enables higher signal levels or a fixed ADC input range and thus a higher possible signal to noise ratio in the presence of significant pileup caused by high positron activity. The higher signal to noise ratio is needed in the PET signal architecture, because of the presence of non-modal time varying electromagnetic fields from the MR, which are a significant source of noise for the wideband PET signal modality.

摘要翻译： 描述了用于优化用于多模态成像的信号路径的数据处理过程和实施例。 实施例和过程利用双重模式MRI / PET扫描器中的闪烁晶体，雪崩光电二极管和电荷敏感前置放大器在正电子发射断层摄影（PET）信号路径中优化信噪比。 双重使用模拟极零电路和数字滤波器可实现更高的信号电平或固定的ADC输入范围，从而在存在由高正电子活动引起的重大堆积的情况下，可能的信噪比更高。 在PET信号架构中需要更高的信噪比，因为存在来自MR的非模态时变电磁场，这是对于宽带PET信号模态的噪声的重要来源。

公开(公告)号：US20130009047A1

公开(公告)日：2013-01-10

申请号：US13539931

申请日：2012-07-02

申请人： Ronald Grazioso ,  Debora Henseler ,  Nan Zhang

发明人： Ronald Grazioso ,  Debora Henseler ,  Nan Zhang

IPC分类号： G01T1/20 ,  G01T1/202

CPC分类号： G01T1/248 ,  G01T1/202

摘要： Systems and methods for correcting output signals from non-linear photosensors, specifically silicon photomultipliers (SiPMs). SiPMs are used in a PET detector to readout light emissions from LSO scintillator crystals. The non-linear output of the SiPM can distort and compress the energy spectrum which is crucial in PET imaging. The non-linearity effect for inter-crystal scattered events can place an energy event outside of the PET detector energy window, resulting in a rejected event. Systems and methods to correct the SiPM non-linearity for inter-crystal scattered events, so as to be able to obtain the proper energy event and produce an accurate medical image, are disclosed.

摘要翻译： 用于校正非线性光电传感器，特别是硅光电倍增管（SiPM）的输出信号的系统和方法。 SiPM用于PET检测器以读出LSO闪烁体晶体的光发射。 SiPM的非线性输出可以扭曲和压缩在PET成像中至关重要的能谱。 晶体间散射事件的非线性效应可以将能量事件置于PET检测器能量窗口之外，导致被拒绝的事件。 公开了用于校正晶间散射事件的SiPM非线性的系统和方法，以便能够获得适当的能量事件并产生精确的医学图像。

公开(公告)号：US08346519B2

公开(公告)日：2013-01-01

申请号：US12530328

申请日：2008-02-26

申请人： Qiying Yin ,  Nan Zhang

发明人： Qiying Yin ,  Nan Zhang

IPC分类号： G06G7/48

CPC分类号： B01J19/0033 ,  B01J2219/00243

摘要： A method of optimising a processing system comprising a plurality of apparatuses includes defining a system model indicative of a predetermined range of apparatus options within a processing system, constraints indicative of feasible interconnections between each apparatus and another apparatus, and parameters indicative of performance criteria associated with each apparatus. The system model is analysed with respect to predetermined criteria to determine a preferred arrangement of apparatuses within the processing system.A parameter relating to at least one apparatus is indicative of the availability and/or the reliability of the apparatus expressed as a function of time.

摘要翻译： 优化包括多个设备的处理系统的方法包括定义指示处理系统内的设备选项的预定范围的系统模型，指示每个设备与另一设备之间的可行互连的约束，以及指示与 每台设备 根据预定标准分析系统模型，以确定处理系统内的装置的优选布置。 与至少一个装置相关的参数表示作为时间的函数表示的装置的可用性和/或可靠性。

公开(公告)号：US20110164253A1

公开(公告)日：2011-07-07

申请号：US12737626

申请日：2009-08-03

申请人： Xiaodong Zhou ,  Nan Zhang ,  Kai Yu Liu ,  Su Yin Oh ,  Jisheng Pan

发明人： Xiaodong Zhou ,  Nan Zhang ,  Kai Yu Liu ,  Su Yin Oh ,  Jisheng Pan

IPC分类号： G01N21/55 ,  C23C14/34 ,  C23C16/44 ,  B05D1/36 ,  C23C14/48 ,  B05D1/06 ,  B32B5/16 ,  B32B3/00 ,  B82Y99/00

CPC分类号： G01N21/554 ,  Y10T428/24372

摘要： A method of modifying a substrate for deposition of charged particles thereon, the method comprising the steps of: providing a substrate that is incapable of bonding to a polyelectrolyte coating that has a charge that is opposite to the charge of the particles that are to be deposited thereon; modifying the surface of the substrate to provide a layer of silicon thereon or therein; and coating the silicon layered surface of the substrate with the polyelectrolyte coating, the polyelectrolyte coating containing functional groups that are capable of forming bonds with said silicon layer and wherein said polyelectrolyte coating enables a substantially even distribution of said charged particles to be deposited thereon.

摘要翻译： 一种修饰底物以沉积带电粒子的方法，所述方法包括以下步骤：提供不能与聚电解质涂层结合的基底，所述聚电解质涂层具有与要沉积的颗粒的电荷相反的电荷 上; 改变衬底的表面以在其上或其中提供硅层; 以及用所述聚电解质涂层涂覆所述基底的所述硅层状表面，所述聚电解质涂层含有能够与所述硅层形成键的官能团，并且其中所述聚电解质涂层能够使所述带电粒子基本均匀地分布在其上。

公开(公告)号：US07964678B2

公开(公告)日：2011-06-21

申请号：US11659621

申请日：2006-02-24

申请人： Licai Wang ,  Zhanxian Gao ,  Wei Li ,  Guotong Zheng ,  Qingxin Dong ,  Riping Liu ,  Xiaohuan Wang ,  Nan Zhang ,  Jingzhuang Wang ,  Shimian Cai

发明人： Licai Wang ,  Zhanxian Gao ,  Wei Li ,  Guotong Zheng ,  Qingxin Dong ,  Riping Liu ,  Xiaohuan Wang ,  Nan Zhang ,  Jingzhuang Wang ,  Shimian Cai

IPC分类号： C08K5/06

CPC分类号： C08F10/00 ,  B01J21/063 ,  B01J35/023 ,  B01J35/1019 ,  C08F110/06 ,  C08F4/6543 ,  C08F4/651 ,  C08F4/6545 ,  C08F2500/15 ,  C08F2500/18

摘要： The catalyst for olefin polymerization contains three components A, B and C. The component A is a solid catalyst containing titanium, magnesium, chlorine element and an internal electron donor, the internal electron donor consists of 1,4-diether [2,2′-dialkoxy-1,1′-biphenyl, 2,2′-dialkoxy-1,1′-binaphthalene, 10,10′-dialkoxy-9,9-biphenanthrene]and organic acid ester or 1,3-diether [9,9-bis(methoxymethyl)fluorine, 2,2-dialky 1-1,3-dimethoxypropane]; the component B is an organoaluminum compound; the component C is external electron donor-organic silicon compound or the 1,4 aromatic diether. The catalyst has high catalytic activity, and can be adjusted in the range from 40,000 to 150,000 gPP/gCat when used in propylene polymerization. The polymer made therefrom has isotactivity of 80 to 99 percent and the molecular weight distribution can be adjusted in a wide range. The invention provides a novel method for preparing the 1,4 aromatic diether.

摘要翻译： 用于烯烃聚合的催化剂包含三种组分A，B和C.组分A是含有钛，镁，氯元素和内电子给体的固体催化剂，内电子给体由1,4-二醚[2,2' 二烷氧基-1,1'-联苯基，2,2'-二烷氧基-1,1'-联萘，10,10'-二烷氧基-9,9-联苯]和有机酸酯或1,3-二醚[ 9-二（甲氧基甲基）氟，2,2-二烷基1-1,3-二甲氧基丙烷]; 组分B是有机铝化合物; 组分C是外电子给体 - 有机硅化合物或1,4-芳族二醚。 该催化剂具有高催化活性，当用于丙烯聚合时可以将其调节至40,000至150,000gPP / gCat。 由其制备的聚合物具有80-99％的等规度，并且可以在宽范围内调节分子量分布。 本发明提供了一种制备1,4芳族二醚的新方法。

公开(公告)号：US20110074426A1

公开(公告)日：2011-03-31

申请号：US12585867

申请日：2009-09-28

申请人： Matthias J. Schmand ,  Markus Vester ,  Nan Zhang

发明人： Matthias J. Schmand ,  Markus Vester ,  Nan Zhang

IPC分类号： G01T1/164 ,  G01T1/20 ,  G01V3/00

CPC分类号： A61B6/4411 ,  A61B5/0035 ,  A61B5/055 ,  A61B6/037 ,  A61B6/4417 ,  G01R33/481 ,  G01T1/1603 ,  G01T1/1644

摘要： An emission tomography detector module and an emission tomography scanner are disclosed. In at least one embodiment, the emission tomography detector modules includes a scintillator to capture an photon, the scintillator emitting a scintillating light on capturing the photon; a first type of solid-state photodetector to detect the scintillating light; and a second type of solid-state photodetector to detect the scintillating light, wherein the first type of solid-state photodetector and the second type of solid-state photodetector are different with respect to a detecting property.

摘要翻译： 公开了一种发射断层摄影检测器模块和发射断层扫描仪。 在至少一个实施例中，发射断层摄影检测器模块包括闪光体以捕获光子，闪烁体在捕获光子时发射闪烁光; 用于检测闪烁光的第一种类型的固态光电检测器; 以及用于检测闪烁光的第二类型的固态光电检测器，其中所述第一类型的固态光电检测器和所述第二类型的固态光电检测器相对于检测特性是不同的。

公开(公告)号：US20100066426A1

公开(公告)日：2010-03-18

申请号：US12558007

申请日：2009-09-11

申请人： Matthias J. Schmand ,  Nan Zhang

发明人： Matthias J. Schmand ,  Nan Zhang

IPC分类号： H03L5/00

CPC分类号： G01T1/248

摘要： A simple, low cost circuit with only passive components, and thus low power consumption, is provided for baseline restoration of an AC coupled signal. The circuit includes a passive network of diodes arranged in a star configuration and an RF-transformer. A differential signal strategy may be employed by including a differential amplifier at the input and output of the passive network.

摘要翻译： 提供了一种简单的低成本电路，仅具有无源组件，因此具有低功耗，用于AC耦合信号的基线恢复。 该电路包括以星形结构布置的二极管的无源网络和RF变压器。 可以通过在无源网络的输入和输出处包括差分放大器来采用差分信号策略。