摘要:
The present invention provides a catheter apparatus, an improved introducer system, and a methodology for creating a bypass on-demand between an unobstructed blood vessel such as the aorta and an obstructed blood vessel such as an obstructed coronary artery in-vivo using a prepared shape-memory alloy cuff and a graft segment in tandem as a shunt. The invention allows the placement and creation of single or multiple bypass grafts without use of a heart-lung machine and without need for stopping the heart of the patient during the coronary artery bypass surgery.
摘要:
This invention relates to intervertebral spacers for use in orthopedic treatment of spinal defects. The intervertebral space is formed of a shaped memory polymer material. The spacer can be fabricated into a desired configuration and then deformed into an alternative or deformed configuration. Cooling the deformed spacer effectively freezes the spacer into its deformed conformation. The deformed configuration can be selected to facilitate implantation of the spacer into a prepared disc space between adjacent vertebrae. During operation, the surgeon can heat the spacer to allow it to revert to its original configuration. The spacer in its original conformation is sized to restore and/or maintain the adjacent vertebrae in a desired conformation and disc space height.
摘要:
A vessel-occluding clamp relies on the shape-memory effect to partially or completely occlude a blood vessel or other body lumen, including bowel, esophagus, stomach, small intestine, colon, and bile ducts. The self-actuating nature of the clamp allows the device work in tight places, be placed through trocars for minimal-access procedures, and forgo the need for conventional or specific applicators. In the preferred embodiment, a clamp according to the invention a pair of opposing jaws connected through a hinge and one or more pieces of shape-memory material associated with the jaws. The shape-memory material may be in the form of one or more wires which extend from the hinge to each jaw. The shape-memory material exhibits a transition temperature such that, when the clamp is exposed to internal body temperatures of the type experienced during a typical surgical procedure, the jaws close to close partially or completely occlude the vessel, and wherein the jaws open below the transition temperature for removal of the clamp or to restore flow through the vessel. The transition temperature is preferably such that the jaws open in the presence of cooling irrigation. Other stimuli, such as the application of an electrical current, may alternatively be used. In an alternative embodiment, a second shape memory material is used having a second transition temperature which, when reached, causes the jaws to open.
摘要:
A cement restrictor is provided for creating a fixed obstruction within a bone. An exemplary cement restrictor includes a member or body that is expandable or transitionable from a first diameter to a second diameter.
摘要:
A medical device such as a stent, surgical staple, bone anchoring device or bone fixation device, intended to be deployed within the body, composes a shape memory alloy (SMA) portion with an austenitic and unaustenitic state with different memorized configurations in each of these states. The SMA which is initially in an initial configuration in which it can be placed into position within the body, can be mechanically deformed into an operational configuration in which it remains deployed within the body.
摘要:
The present invention provides a catheter apparatus, an introducer system, and a methodology for creating a vascular bypass on-demand between an unobstructed blood vessel such as the aorta and an obstructed blood vessel such as an obstructed coronary artery in-vivo using a previously excised vascular segment as a shunt. The invention allows the placement and creation of single or multiple vascular grafts without use of a heart-lung machine and without need for stopping the heart of the patient during the coronary artery bypass surgery.
摘要:
A synergistic pharmaceutical combination and composition are disclosed for the treatment of gastritis and peptic ulcer containing a therapeutic amount of a proton pump inhibitor such as e.g., omeprazole or lansoprazole, which increases intragastric pH, and a therapeutic amount of an acid degradable antibacterial compound such as a penicillin or a macrolide. In particular, the combination is directed to the treatment of infections caused by Helicobacter pylori by raising the bioavailability of acid degradable antibacterial compounds.
摘要:
Surgical needles are fabricated from a shape memory alloy. The alloy has a low temperature state, in which the needle is formable into an elongated shape to pass through an elongated tube, and a high temperature state, in which the needle forms an arc. The needle is particularly adapted for use in endoscopic surgery. A needle that has a remembered curved shape is straightened and passed to a surgical site through a cannula. It is then returned to its curved shape by heating it at the surgical site. After use, it is withdrawn through the cannula.
摘要:
A stapling device utilizes heat recoverable material (the driver) having shape memory to drive staples through materials to be joined and in one embodiment, against an anvil for crimping the ends of the staples. The heat recoverable material, preferably a metal such as Nitinol, may have heat applied by a heater mounted on at least one surface thereof or by induction or other method of heating. If a heater is mounted on a surface of the driver, upon insertion of the driver into the staple device, the heater makes electrical connection with terminals for connection to a supply circuit. In a specific embodiment staples may be provided, fabricated from heat recoveralbe metal so that each staple may carry its own heat recoverable, staple driving element. The staple tines may have a heat recoverable shape with the ends of the tines directed toward one another so that staple closure occures as heat migrates from the staple driving region to the tines thereof. Alternatively, the heat recoverable staple may complete a circuit through the staple upon contact with the anvil, thus heating the staple. Alternatively, the staples may have a heat recovered state with the ends parallel to one another so that the application of heat will open the staples and permit ready removal.
摘要:
A transluminally placed endovascular graft prosthesis includes a helically wound coil having a generally tubular shape and is made of a shape memory Nitinol alloy having a transition temperature in the range of 115.degree.-125.degree. F. After placement within a body blood vessel and upon heating of the prosthesis to its transition temperature, the prosthesis expands so as to become firmly anchored to the inside wall of the body blood vessel. After expansion the diameter of the lumen of the prosthesis is approximately equal to the diameter of the body blood vessel passageway. The prosthesis may also be used in other body passageways.