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243 条记录 (耗时 0.024 秒)

    Brain fluid ion concentration modification for treating neurological disorders
    73.
    发明授权
    Brain fluid ion concentration modification for treating neurological disorders 有权
    用于治疗神经障碍的脑液离子浓度修饰

    公开(公告)号：US06709426B2

    公开(公告)日：2004-03-23

    申请号：US10174257

    申请日：2002-06-18

    申请人： Johan F. M. Gijsbers ,  Frans L. H. Gielen

    发明人： Johan F. M. Gijsbers ,  Frans L. H. Gielen

    IPC分类号： A61M3100

    CPC分类号： A61M1/3621 ,  A61M1/34 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3687 ,  A61M2027/004 ,  A61M2202/0464 ,  A61M2205/50

    摘要： Epilepsy and other neurological disorders that are affected by the electrical potential difference between intracellular fluid and extra-cellular fluid and therefore the cell membrane potentials, and therefore the thresholds for the communication between brain cells can be controlled by re-circulating extra-cellular brain fluid after the fluid has been treated to alter its ion concentrations. A computer-controlled pump can precisely control the extraction and delivery of brain fluid after the ion concentration of the fluid is appropriately adjusted, e.g. guided by the Goldmann equation. Well-known techniques for modifying ion concentrations can be used to raise or lower ion concentrations as needed.

    摘要翻译： 受细胞内液体和细胞外液体之间的电势差异影响的癫痫和其他神经系统疾病，因此细胞膜电位的影响，因此脑细胞之间的通信的阈值可以通过再循环细胞外脑液 在流体被处理以改变其离子浓度之后。 计算机控制的泵可以在适当调节流体的离子浓度之后，精确地控制脑液的提取和输送。 在Goldmann方程的指导下。 用于改变离子浓度的众所周知的技术可以用于根据需要提高或降低离子浓度。

    Method and apparatus for determining hemodialysis parameters
    74.
    发明申请
    Method and apparatus for determining hemodialysis parameters 有权

    公开(公告)号：US20030220600A1

    公开(公告)日：2003-11-27

    申请号：US10375899

    申请日：2003-02-27

    发明人： Frank A. Gotch ,  Thomas I. Folden

    IPC分类号： A61M037/00

    CPC分类号： A61M1/3653 ,  A61M1/16 ,  A61M1/1605 ,  A61M1/1607 ,  A61M1/1609 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3655 ,  A61M1/3656 ,  A61M1/3658 ,  A61M1/3661 ,  A61M2202/0498 ,  A61M2205/15 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3368 ,  A61M2205/50

    摘要： This invention provides a method and apparatus for calculating a hemodialysis parameter, especially blood access flow rate, using multiple dialysance values. The dialysance values may be calculated based upon either sodium or urea concentrations. One dialysance value can be determined for conditions in which a patient's arterial line withdraws blood from an upstream location in a patient's fistula and treated blood is returned by a venous line to a downstream location in a patient's fistula. The second dialysance value can be determined when the lines have been reconfigured so that the arterial line withdraws blood from a downstream portion of a patient's fistula and the venous line returns treated blood to an upstream portion of a patient's fistula. Since it is possible to determine the dialysance values solely from concentration measurements made on the dialysate side of the dialysis apparatus, the present method and apparatus provide a non-invasive means for determining hemodialysis parameters such as blood access flow rate and recirculation.

    Differential conductivity hemodynamic monitor
    77.
    发明申请
    Differential conductivity hemodynamic monitor 失效
    差分电导率血液动力学监测仪

    公开(公告)号：US20030016002A1

    公开(公告)日：2003-01-23

    申请号：US10238164

    申请日：2002-09-10

    发明人： James M. Brugger ,  George W. Buffaloe IV ,  Francis T. Ogawa

    IPC分类号： G01N027/00

    CPC分类号： A61M1/16 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3658 ,  A61M1/3659 ,  A61M1/3661 ,  A61M1/3669 ,  G01F1/7046 ,  G01F1/708 ,  G01F1/7088

    摘要： A flow rate of a fluid flowing in a tube is quantitatively determined by altering the electrical conductivity of the fluid by injection of a bolus of saline. The electrical conductivity of the altered conductivity is measured over the time it takes the altered conductivity fluid to pass a conductivity measuring location. The measured conductivity is integrated over the time it take to pass the conductivity measuring location. The integral is interpreted to determine the flow rate.

    摘要翻译： 在管中流动的流体的流速通过注射大量盐水改变流体的电导率而定量地确定。 在改变的导电流体通过电导率测量位置的时间内测量改变的导电性的导电性。 测量的电导率在通过电导率测量位置所需的时间内积分。 积分被解释为确定流量。

    Device and method for controlling infusion of liquid in an extracorporeal blood circuit
    78.
    发明申请
    Device and method for controlling infusion of liquid in an extracorporeal blood circuit 有权
    用于控制在体外血液回路中液体注入的装置和方法

    公开(公告)号：US20020121471A1

    公开(公告)日：2002-09-05

    申请号：US09980864

    申请日：2002-04-12

    发明人： Renato Pedrazzi

    IPC分类号： C02F001/44

    CPC分类号： A61M1/342 ,  A61M1/1607 ,  A61M1/1609 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3441 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3669 ,  A61M39/28 ,  A61M2230/30

    摘要： A dialysis machine having an extracorporeal blood circuit having an arterial pipe and a venous pipe respectively connected to an inlet and an outlet of a blood compartment of a filter having a blood compartment and a dialysis liquid compartment separated by a semi-permeable membrane; means for determining a sequence of infusion of a liquid in the extracorporeal blood circuit, from at least one characteristic value (FF, TMPave, Kuf) correlated with the concentration of the blood (CE) and/or a filtration efficiency of the filter; and means for infusing the infusion solution in the arterial pipe and in the venous pipe in accordance with the determined infusion sequence.

    摘要翻译： 一种具有体外血液循环的透析机，其具有动脉管和静脉管，所述静脉管分别连接到具有由半透膜隔开的血液室和透析液室的过滤器的血液室的入口和出口; 用于从与血液浓度（CE）相关的至少一个特征值（FF，TMPave，Kuf）和/或过滤器的过滤效率确定在体外血液回路中液体的输注顺序的装置; 以及用于根据确定的输注顺序将输注溶液注入动脉管和静脉管中的装置。

    System and method for measuring blood urea nitrogen, blood osmolarity, plasma free hemoglobin and tissue water content
    80.
    发明授权
    System and method for measuring blood urea nitrogen, blood osmolarity, plasma free hemoglobin and tissue water content 失效
    测量血液尿素氮，血液渗透压，血浆游离血红蛋白和组织含水量的系统和方法

    公开(公告)号：US06246894B1

    公开(公告)日：2001-06-12

    申请号：US09028809

    申请日：1998-02-24

    申请人： Robert R. Steuer ,  David R. Miller

    发明人： Robert R. Steuer ,  David R. Miller

    IPC分类号： A61B500

    CPC分类号： A61B5/14535 ,  A61B5/14546 ,  A61B5/14557 ,  A61B5/6826 ,  A61B5/6838 ,  A61B5/6843 ,  A61M1/361 ,  A61M1/3612 ,  G01N21/0303 ,  G01N2021/036

    摘要： Systems and methods are provided for noninvasively measuring the levels of urea, blood osmolarity (or Na+), plasma free hemoglobin and tissue water content in a patient's blood or tissue. Light of selected wavelengths is passed through blood or body tissue and the transmitted or reflected light is detected and the detected signals can be electronically compared and manipulated to provide the non-invasive, continuous and quantitative display of a patient's blood urea, blood osmolarity (or Na+), plasma free hemoglobin and tissue water content.

    摘要翻译： 提供系统和方法用于非侵入性地测量患者血液或组织中的尿素水平，血液渗透压（或Na +），血浆游离血红蛋白和组织水含量。 所选波长的光通过血液或身体组织，并且检测到透射或反射光，并且可以电子地比较和操纵检测到的信号，以提供患者血液尿素的非侵入性，连续和定量显示，血液渗透压（或 Na +），血浆游离血红蛋白和组织含水量。