Aqueous ophthalmic composition
    84.
    发明授权
    Aqueous ophthalmic composition 有权
    水性眼用组合物

    公开(公告)号:US09050369B2

    公开(公告)日:2015-06-09

    申请号:US13720734

    申请日:2012-12-19

    CPC classification number: A61K47/46 A61K9/0048 A61K47/02 A61K47/44

    Abstract: This invention relates to an aqueous ophthalmic composition comprising (A) polyoxyethylene castor oil and (B) sesame oil. According to the aqueous ophthalmic composition of the present invention, defoaming time is reduced, preservative efficacy is enhanced and photostability is improved.

    Abstract translation: 本发明涉及含有(A)聚氧乙烯蓖麻油和(B)芝麻油的水性眼用组合物。 根据本发明的水性眼用组合物,消泡时间降低,防腐效果提高,光稳定性提高。

    NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF
    85.
    发明申请
    NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF 有权
    新的苄基胆碱衍生物或其盐

    公开(公告)号:US20150065728A1

    公开(公告)日:2015-03-05

    申请号:US14389139

    申请日:2013-03-27

    Inventor: Takashi Shimizu

    Abstract: A novel compound which has excellent ultraviolet-absorbing function (especially UVA absorbing function) and excellent hydrophilicity. A benzylidene azolidine derivative represented by structural formula (I) or a salt thereof. In structural formula (I), n represents an integer of 1-5; A1 represents O, S or N-A4; and each of A2, A3 and A4 independently represents a hydrogen atom, an alkyl group which may be substituted by a hydroxyl group and has 1-8 carbon atoms, or the like (provided that at least one of A2, A3 and A4 contains one or more hydroxyl groups). In this connection, when n is an integer of 2-5, the plurality of A3O— moieties may be the same as or different.

    Abstract translation: 具有优异的紫外线吸收功能(特别是UVA吸收功能)和优异亲水性的新型化合物。 由结构式(I)表示的亚苄基偶氮化合物衍生物或其盐。 在结构式(I)中,n表示1-5的整数; A1代表O,S或N-A4; A2,A3和A4各自独立地表示氢原子,可以被羟基取代并具有1-8个碳原子的烷基等(条件是A2,A3和A4中的至少一个包含一个 或更多的羟基)。 在这一点上,当n为2-5的整数时,多个A3O-部分可以相同或不同。

    AQUEOUS OPHTHALMIC COMPOSITION
    86.
    发明申请
    AQUEOUS OPHTHALMIC COMPOSITION 审中-公开
    水性眼科组合物(AQUEOUS OPHTHALMIC COMPOSITION)

    公开(公告)号:US20140371123A1

    公开(公告)日:2014-12-18

    申请号:US14477502

    申请日:2014-09-04

    Inventor: Atsuko NAKATA

    Abstract: This invention relates to an aqueous ophthalmic composition comprising (A) polyoxyethylene castor oil in which the number of moles of added ethylene oxide is 2 to 30, and (B) at least one member selected from the group consisting of castor oil and vitamin A. According to the aqueous ophthalmic composition of the present invention, the defoaming time can be reduced even when foam is generated by vibration or impact.

    Abstract translation: 本发明涉及一种水性眼用组合物,其包含(A)加成环氧乙烷的摩尔数为2〜30的聚氧乙烯蓖麻油,(B)选自蓖麻油和维生素A的至少一种。 根据本发明的水性眼用组合物,即使通过振动或冲击产生泡沫,也可以降低消泡时间。

    AGENT FOR THE PREVENTION, IMPROVEMENT OR TREATMENT OF RETINAL DISEASE
    88.
    发明申请
    AGENT FOR THE PREVENTION, IMPROVEMENT OR TREATMENT OF RETINAL DISEASE 审中-公开
    预防,改善或治疗退行性疾病的代理人

    公开(公告)号:US20130303625A1

    公开(公告)日:2013-11-14

    申请号:US13775605

    申请日:2013-02-25

    Abstract: A prophylactic, ameliorating or therapeutic agent for a retinal disease, the agent comprising geranylgeranylacetone which (a) is a mixture of (5E,9E,13E)-geranylgeranylacetone and (5Z,9E,13E)-geranylgeranylacetone, the (5E,9E,13E)-geranylgeranylacetone content of the mixture being 80% by weight or more, (b) consists of (5E,9E,13E)-geranylgeranylacetone, or (c) consists of (5Z,9E,13E)-geranylgeranylacetone directly suppresses the death of a retinal cell, thereby fundamentally preventing, ameliorating or treating the retinal disease.

    Abstract translation: (5E,9E,13E)ger anyl ger anyl anyl anyl one one and,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 13E)ger anyl ger anyl anyl anyl one one death death death death death death,,,,,death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death death 的视网膜细胞,从而从根本上防止,改善或治疗视网膜疾病。

    Nozzle for a liquid container and a liquid container
    89.
    发明申请
    Nozzle for a liquid container and a liquid container 有权
    用于液体容器和液体容器的喷嘴

    公开(公告)号:US20040079766A1

    公开(公告)日:2004-04-29

    申请号:US10686409

    申请日:2003-10-14

    Inventor: Shigehiko Kokubo

    CPC classification number: B65D47/18 B65D47/0838 B65D47/123

    Abstract: A lower portion of a nozzle is held hermetically in contact with an inner circumferential surface of the tubular neck of a container, and an inner surface of a cap is mounted to an outer surface of the tubular neck. A discharging hole of the nozzle is hermetically sealed by an inner top surface of the cap. A ring-shaped projection is formed on an upper portion of the nozzle for hermetically contacting an inner surface of the cap. Thereby, double sealing is provided in cooperation with hermetic sealing of the discharging hole of the nozzle by the inner top surface of the cap. The nozzle prevents a liquid leak and liquid dripping from the nozzle and form liquid drops independently of a dripping angle.

    Abstract translation: 喷嘴的下部与容器的管状颈部的内周面气密地保持接触,盖的内表面安装在管状颈部的外表面。 喷嘴的排出孔被盖的内顶表面气密地密封。 在喷嘴的上部形成有环形突起,用于使盖的内表面气密接触。 因此,通过盖的内顶表面与喷嘴的排出孔的气密密封配合来提供双重密封。 喷嘴防止液体泄漏和液体从喷嘴滴落并独立于滴水角度形成液滴。

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