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81.发明申请公开(公告)号：US20090324625A1
公开(公告)日：2009-12-31
申请号：US12507430
申请日：2009-09-03
Applicant: Guixue Yu , Jun Li , William R. Ewing , Richard B. Sulsky , James J. Li , Joseph Anthony Tino
Inventor： Guixue Yu , Jun Li , William R. Ewing , Richard B. Sulsky , James J. Li , Joseph Anthony Tino
IPC: A61K39/00 , A61K31/437
CPC classification number: C07D487/04 , C07D231/56 , C07D261/20 , C07D471/04 , C07D513/04
Abstract: Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula I wherein R1, R1′, R2, R3, R4, Xa, Y, Z and n are as described herein. The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.
Abstract translation: 提供了可用于刺激生长激素的内源性生产或释放的新型杂环芳族化合物，所述化合物具有式I的通式结构，其中R1，R1'，R2，R3，R4，Xa，Y，Z和n如上所述 这里。 本文提供的化合物可用于治疗肥胖症，骨质疏松症（改善骨密度）和改善肌肉质量和肌肉力量。
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82.发明申请公开(公告)号：US20090319846A1
公开(公告)日：2009-12-24
申请号：US12448536
申请日：2006-12-30
Applicant: Xiaojun Ma , Jun Li , Hang Liu
Inventor： Xiaojun Ma , Jun Li , Hang Liu
CPC classification number: H04L1/1621 , H04H60/11 , H04L1/1877 , H04L1/1883 , H04L1/1887 , H04L12/1827 , H04L12/1868 , H04L2001/0093
Abstract: An adaptive error correction method for data transmission and the devices thereof are disclosed. By comparing the announced recovery data and data requested for error correction, no redundant join messages will be sent if the recovery data have been announced before. This will greatly reduce the number messages and save the band width of transmission.
Abstract translation: 公开了一种用于数据传输的自适应纠错方法及其装置。 通过比较所公布的恢复数据和纠错请求的数据，如果恢复数据已经公布，则不会发送冗余加入消息。 这将大大减少数字消息并节省传输带宽。
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83.发明授权公开(公告)号：US07592354B2
公开(公告)日：2009-09-22
申请号：US11273169
申请日：2005-11-14
Applicant: Guixue Yu , Jun Li , William R. Ewing , Richard B. Sulsky , James J. Li , Joseph Anthony Tino
Inventor： Guixue Yu , Jun Li , William R. Ewing , Richard B. Sulsky , James J. Li , Joseph Anthony Tino
IPC: A61K31/395 , C07D487/02
CPC classification number: C07D487/04 , C07D231/56 , C07D261/20 , C07D471/04 , C07D513/04
Abstract: Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula I wherein R1, R1′, R2, R3, R4, Xa, Y, Z and n are as described herein. The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.
Abstract translation: 提供了可用于刺激生长激素的内源性生产或释放的新型杂环芳族化合物，所述化合物具有式I的通式结构，其中R1，R1'，R2，R3，R4，Xa，Y，Z和n如上所述 这里。 本文提供的化合物可用于治疗肥胖症，骨质疏松症（改善骨密度）和改善肌肉质量和肌肉力量。
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公开(公告)号：US20090233842A1
公开(公告)日：2009-09-17
申请号：US12093437
申请日：2006-11-13
Applicant: Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William E. Bunney, JR. , Marquis P. Vawter , Edward G. Jones , Prabhakara V. Choudary , Richard M. Myers , Alan F. Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
Inventor： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William E. Bunney, JR. , Marquis P. Vawter , Edward G. Jones , Prabhakara V. Choudary , Richard M. Myers , Alan F. Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
CPC classification number: C12Q1/6883 , A61K38/03 , A61K38/10 , A61K38/1774 , A61K38/1825 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , G01N33/5023 , G01N2800/304
Abstract: The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.
Abstract translation: 本申请涉及心理障碍的治疗和诊断，包括双相情感障碍，重症抑郁障碍和精神分裂症。 本发明提供了新的诊断标记和测定，以及用于开发和发现可用于治疗患有精神疾病的患者的药剂和化合物的研究工具。
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公开(公告)号：US07586315B2
公开(公告)日：2009-09-08
申请号：US11836795
申请日：2007-08-10
Applicant: Shih-Fang Wong , Tsung-Jen Chuang , Jun Li
Inventor： Shih-Fang Wong , Tsung-Jen Chuang , Jun Li
IPC: G01R27/08
CPC classification number: G01R31/3004 , G01R31/2839
Abstract: A method for testing voltage endurance of a electronic component, includes: generating an oscillating signal; amplifying the oscillating signal; transforming the amplified oscillating signal to generate a transformed signal; blocking a negative voltage of the transformed signal to generate a test signal to be transmitted to the electronic component; and detecting electrical characteristics of the electronic component to generate result data.
Abstract translation: 一种用于测试电子部件的耐压性的方法，包括：产生振荡信号; 放大振荡信号; 变换放大的振荡信号以产生变换信号; 阻断变换后的信号的负电压以产生要发送到电子部件的测试信号; 并检测电子部件的电气特性以产生结果数据。
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Patent Agency Ranking
86.发明授权公开(公告)号：US07579360B2
公开(公告)日：2009-08-25
申请号：US11448947
申请日：2006-06-07
Applicant: James J. Li , Lawrence G. Hamann , Haixia Wang , Zheming Ruan , Christopher B. Cooper , Jun Li , Jeffrey A. Robl
Inventor： James J. Li , Lawrence G. Hamann , Haixia Wang , Zheming Ruan , Christopher B. Cooper , Jun Li , Jeffrey A. Robl
IPC: A01N43/42 , A61K31/44 , C07D513/02 , C07D515/02
CPC classification number: C07D471/04
Abstract: Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W, L, R3, R3a, R3b and R4 are defined herein.
Abstract translation: 提供了新的化合物，其为11-β-羟基类固醇脱氢酶I型抑制剂。 11-β-羟基类固醇脱氢酶I型抑制剂可用于治疗，预防或减缓需要11-β-羟基类固醇脱氢酶I型抑制剂治疗的疾病进展。 这些新化合物具有以下结构：其立体异构体或前药或其药学上可接受的盐，其中W，L，R3，R3a，R3b和R4如本文所定义。
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87.发明申请METHODS FOR THE IDENTIFICATION OF IKKALFA FUNCTION AND OTHER GENES USEFUL FOR TREATMENT OF INFLAMMATORY DISEASES 审中-公开用于鉴定IKKALFA功能的方法和其他有助于治疗炎症疾病的基因公开(公告)号：US20090186010A1
公开(公告)日：2009-07-23
申请号：US12271198
申请日：2008-11-14
Applicant: Jun Li , Adedayo Hanidu , Xiang Li , Gregory Whitten Peet , Sheenah Mische , Kenneth Marcu
Inventor： Jun Li , Adedayo Hanidu , Xiang Li , Gregory Whitten Peet , Sheenah Mische , Kenneth Marcu
CPC classification number: C12Q1/6883 , C12Q2600/158 , G01N33/5023
Abstract: The invention provides a method for identifying genes involved in the NF-κB pathway comprised of the steps of determining the level of expression of a gene in an experimental sample obtained from the cells having deficient levels of a component of the NF-κB pathway; determining the level of expression of said gene in a control sample obtained from wild type cells having levels of a component of a biological pathway; selecting genes having a level of expression that are modulated in said experimental sample relative to said wild type sample. The invention also provides a method of treating inflammatory related diseases by modulating the activity of IKKα.
Abstract translation: 本发明提供了鉴定涉及NF-κB途径的基因的方法，其包括确定从具有NF-κB途径成分水平不足的细胞获得的实验样品中基因表达水平的步骤; 确定从具有生物学途径成分水平的野生型细胞获得的对照样品中所述基因的表达水平; 选择具有相对于所述野生型样品在所述实验样品中调节的表达水平的基因。 本发明还提供了通过调节IKKα的活性来治疗炎性相关疾病的方法。
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88.发明申请Fast and High-Throughput Search Engine for Materials for Lithium-Ion Batteries Using Quantum Simulations 审中-公开使用量子模拟的锂离子电池材料快速高通量搜索引擎公开(公告)号：US20090157369A1
公开(公告)日：2009-06-18
申请号：US12334170
申请日：2008-12-12
Applicant: Jun Li , Deepak Srivastava
Inventor： Jun Li , Deepak Srivastava
IPC: G06G7/58
Abstract: Provided are methods and systems for determining the structure of a composite or solid solution material for an electrode in lithium-ion batteries. In one embodiment, a method is presented where a building-block database of hypothetical structures containing only one transition metal atom is constructed by use of quantum simulation. Then, a composite model set of structures containing two or more transition metal atoms is constructed by calculating a linear average of parent components from the building-block database of hypothetical structures to determine lattice constants and atomic coordinates of candidates. The composite model set is screened with a local order matrix to subclassify composite models into a subset, such that the composite models share the same property in local transition metal ordering. Still yet, a representative from each subset is selected and a quantum simulation on the representative models is performed to determine the structure of the material.
Abstract translation: 提供了用于确定锂离子电池中的电极的复合材料或固溶体材料的结构的方法和系统。 在一个实施例中，提出了一种方法，其中通过使用量子模拟构建仅包含一个过渡金属原子的假想结构的构建块数据库。 然后，通过从假设结构的构建块数据库中计算母体成分的线性平均值来确定候选物的晶格常数和原子坐标来构建包含两个或更多个过渡金属原子的结构的复合模型集合。 复合模型集用局部顺序矩阵进行筛选，将复合模型分类为子集，使得复合模型在本地过渡金属排序中共享相同的属性。 仍然选择来自每个子集的代表，并且对代表性模型进行量子模拟以确定材料的结构。
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89.发明授权Method for manufacturing a composite tire of polyurethane tread and radial carcase 有权聚氨酯胎面和径向车箱复合轮胎的制造方法公开(公告)号：US07524446B2
公开(公告)日：2009-04-28
申请号：US10875672
申请日：2004-06-23
Applicant: Hai Zhang , Tie-Jun Ma , Yan-Ping Ye , Yu-Hua Yi , Jian-Rong Shen , Jun Li
Inventor： Hai Zhang , Tie-Jun Ma , Yan-Ping Ye , Yu-Hua Yi , Jian-Rong Shen , Jun Li
IPC: B29C39/10
CPC classification number: C08G18/7678 , B29D30/52 , B29K2075/00 , B60C1/00 , B60C1/0016 , C08G18/10 , C08G18/12 , C08G18/4854 , C08G18/69 , C08G18/698 , C08G2380/00 , C08K3/04 , C08K3/36 , C08K9/06 , C08L2666/54 , C09J175/04 , Y02T10/862 , Y10S264/77 , C08G18/3203 , C08G18/3893
Abstract: Methods for manufacturing a composite rubber tire with a polyurethane tread comprise: treating an outer surface of an internal rubber body; preparing a polyurethane pre-polymer; improving the polyurethane pre-polymer; and applying the polyurethane pre-polymer to the treated outer surface of the internal rubber body to mold a polyurethane tread. Thereby, the composite rubber tire with the polyurethane tread is achieved and has excellent characteristics such as low rolling resistance, low oil consumption, excellent durability and low environmental contamination. Additionally, the methods constitute simple manufacturing processes that reduce manufacturing costs of the composite rubber tire with the polyurethane tread.
Abstract translation: 制造具有聚氨酯胎面的复合橡胶轮胎的方法包括：处理内部橡胶体的外表面; 制备聚氨酯预聚物; 改进聚氨酯预聚物; 并将聚氨酯预聚物施加到内部橡胶体的经处理的外表面上以模制聚氨酯胎面。 由此，实现了具有聚氨酯胎面的复合橡胶轮胎，并且具有低滚动阻力，低油耗，优异的耐久性和低环境污染等优异的特性。 另外，这些方法构成简单的制造工艺，其降低了具有聚氨酯胎面的复合橡胶轮胎的制造成本。
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公开(公告)号：US07505172B2
公开(公告)日：2009-03-17
申请号：US10697986
申请日：2003-10-31
Applicant: Gary L. Vondran, Jr. , Jun Li
Inventor： Gary L. Vondran, Jr. , Jun Li
IPC: H04N1/40
CPC classification number: G06F3/1212 , G06F3/122 , G06F3/124 , G06F3/1247 , G06F3/1285 , G06F3/1288 , G06K15/1822 , G06K15/1856 , G06K15/1857 , G06K15/1888
Abstract: Systems and methods according to the present invention provide the capability to identify, record and employ object reuse in print jobs. Reuse information, e.g., a number of instances of a particular object and/or the pages wherein the object is used, is identified as part of print job processing. Subsequent printing process, e.g., object caching and print job partitioning, can then use the reuse information.
Abstract translation: 根据本发明的系统和方法提供了在打印作业中识别，记录和使用对象重用的能力。 重复使用信息，例如特定对象的多个实例和/或其中使用对象的页面被识别为打印作业处理的一部分。 随后的打印过程，例如对象缓存和打印作业分区，可以使用重用信息。
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