公开(公告)号：US20050003386A1

公开(公告)日：2005-01-06

申请号：US10779412

申请日：2004-02-13

Applicant: Guillermo Bazan ,  Shu Wang ,  Bin Liu

Inventor： Guillermo Bazan ,  Shu Wang ,  Bin Liu

IPC: C07F5/02 ,  C07H21/00 ,  C07H21/04 ,  C08G63/48 ,  C08G63/91 ,  C12Q1/68 ,  G01N20060101

CPC classification number: C12Q1/6818 ,  Y10T436/143333 ,  C12Q2565/101

Abstract: Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor PBP that can bind to the target polynucleotide. The sensor PBP comprises a signaling chromophore to absorb energy from the excited multichromophore and emit light in the presence of the target polynucleotide. The methods can be used in multiplex form. Kits comprising reagents for performing such methods are also provided.

Abstract translation: 提供了用于测定靶多核苷酸样品的方法，组合物和制品。 将怀疑含有靶多核苷酸的样品与聚阳离子多重色素和可与靶多核苷酸结合的传感器PBP接触。 传感器PBP包括信号发色团，以吸收来自激发的多色素的能量并在靶多核苷酸的存在下发光。 该方法可以多路复用形式使用。 还提供了包含用于执行这些方法的试剂的试剂盒。

公开(公告)号：USD1043335S1

公开(公告)日：2024-09-24

申请号：US29856527

申请日：2022-10-14

Applicant: Bin Liu

Designer： Bin Liu

Abstract: FIG. 1 is a front, right and top perspective view of a card box showing my new design;
FIG. 2 is a rear, left and bottom perspective view thereof;
FIG. 3 is a front view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a left view thereof;
FIG. 6 is a right view thereof;
FIG. 7 is a top view thereof;
FIG. 8 is a bottom view thereof;
FIG. 9 is a partially exploded perspective view thereof, showing a top portion removed, and a middle portion and a bottom portion assembled;
FIG. 10 is an exploded perspective view thereof, showing a top, middle and a bottom portion; and,
FIG. 11 is an exploded perspective view thereof, showing a middle portion in an unfolded condition.

公开(公告)号：USD1025241S1

公开(公告)日：2024-04-30

申请号：US29896447

申请日：2023-07-04

Applicant: Bin Liu

Designer： Bin Liu

Abstract: FIG. 1 is a front perspective view of a step machine, showing my new design;
FIG. 2 is a rear perspective view thereof;
FIG. 3 is a front elevational view thereof;
FIG. 4 is a rear elevational view thereof;
FIG. 5 is a left side view thereof, the right side view thereof being a mirror image of FIG. 5;
FIG. 6 is a top plan view thereof;
FIG. 7 is a partial enlarged view of FIG. 1;
FIG. 8 is a partial enlarged view of FIG. 1;
FIG. 9 is a partial enlarged view of FIG. 2;
FIG. 10 is a partial enlarged view of FIG. 2;
FIG. 11 is a partial enlarged view of FIG. 3; and,
FIG. 12 is a partial enlarged view of FIG. 5.
The dashed lines in the figures are for the purpose of illustrating portions of the step machine, which form no part of the claimed design.
The dash-dot-dot lines in the FIGS. 2 and 4 are for the purpose of illustrating portions of the step machine, which form no part of the claimed design.
The dash-dot-dash lines are for annotating enlarged views, which form no part of the claimed design.

公开(公告)号：US11911650B1

公开(公告)日：2024-02-27

申请号：US18212728

申请日：2023-06-22

Applicant: Bin Liu

Inventor： Bin Liu

IPC: A63B21/00

CPC classification number: A63B21/4035 ,  A63B21/4034 ,  A63B2209/00

Abstract: The present invention provides a multifunctional fitness frame with a reversible pedal structure, which comprises a main frame, a pull ring arranged on the main frame and a pedal arranged on the main frame, wherein the pedal is arranged on the main frame in a reversible manner, and a support tube and a rotating shaft are also penetrated on the main frame; the pedal is turned over by the rotating shaft and leans against the support tube to facilitate the user to practice paddling; and the pedal can also be turned over and leaned against the ground by the rotating shaft to realize storage, so that the user can practice other actions conveniently.

公开(公告)号：USD951756S1

公开(公告)日：2022-05-17

申请号：US29787617

申请日：2021-06-08

Applicant: Bin Liu

Designer： Bin Liu

公开(公告)号：USD951755S1

公开(公告)日：2022-05-17

申请号：US29786686

申请日：2021-06-02

Applicant: Bin Liu

Designer： Bin Liu

公开(公告)号：US09506740B2

公开(公告)日：2016-11-29

申请号：US13513052

申请日：2010-12-01

Applicant: Mark Brezinski ,  Bin Liu ,  Ehsan Azimi

Inventor： Mark Brezinski ,  Bin Liu ,  Ehsan Azimi

IPC: G01B11/02 ,  G01B9/02 ,  A61B5/00 ,  G01N21/47 ,  G01N21/17

CPC classification number: G01B9/02091 ,  A61B5/0066 ,  A61B5/7257 ,  G01B9/02044 ,  G01B9/02074 ,  G01N21/4795 ,  G01N2021/1787

Abstract: Systems and methods for enhancing spectral domain optical coherence tomography (OCT] are provided. In particular, a system and method for calibration of spectral interference signals using an acquired calibration signal are provided. The calibration signal may be logarithmically amplified to further improve the accuracy of the calibration. From the calibration signal, a series of more accurate calibration data are calculated. An acquired spectral interference signal is calibrated using these calibration data. Moreover, systems that include logarithmic amplification of the spectral interference signal and variable band-pass filtering of the spectral interference signal are provided. Such systems increase the dynamic range and visualization capabilities relative to conventional spectral domain OCT systems.

Abstract translation: 提供了增强频域光学相干断层扫描（OCT）的系统和方法，特别提供了一种使用采集的校准信号校准光谱干扰信号的系统和方法，校准信号可以对数放大，以进一步提高 校准，从校准信号中计算出一系列更准确的校准数据，采用这些校准数据对采集到的光谱干涉信号进行校准，而且包括频谱干扰信号的对数放大和可变带通滤波的系统 提供了光谱干扰信号，相对于常规光谱域OCT系统，这种系统增加了动态范围和可视化能力。

公开(公告)号：US20160087098A1

公开(公告)日：2016-03-24

申请号：US14859447

申请日：2015-09-21

Applicant: Bin Liu ,  Sun-Min Kim ,  Shigenobu Maeda

Inventor： Bin Liu ,  Sun-Min Kim ,  Shigenobu Maeda

IPC: H01L29/78 ,  H01L29/167 ,  H01L29/51 ,  H01L29/08 ,  H01L29/161 ,  H01L29/423

CPC classification number: H01L29/7833 ,  H01L21/324 ,  H01L29/0649 ,  H01L29/0847 ,  H01L29/1054 ,  H01L29/161 ,  H01L29/167 ,  H01L29/42364 ,  H01L29/513 ,  H01L29/66545 ,  H01L29/785 ,  H01L29/78684 ,  H01L29/78696

Abstract: Semiconductor devices are provided including an active layer, a gate structure, a spacer, and a source/drain layer. The active layer is on the substrate and includes germanium. The active layer includes a first region having a first germanium concentration, and a second region on both sides of the first region. The second region has a top surface getting higher from a first portion of the second region adjacent to the first region toward a second portion of the second region far from the first region, and has a second germanium concentration less than the first germanium concentration. The gate structure is formed on the first region of the active layer. The spacer is formed on the second region of the active layer, and contacts a sidewall of the gate structure. The source/drain layer is adjacent to the second region of the active layer.

Abstract translation: 提供了包括有源层，栅极结构，间隔物和源极/漏极层的半导体器件。 有源层在基底上，包括锗。 有源层包括具有第一锗浓度的第一区域和位于第一区域两侧的第二区域。 第二区域具有从与第一区域相邻的第二区域的第一部分朝向远离第一区域的第二区域的第二部分更高的顶表面，并且具有小于第一锗浓度的第二锗浓度。 栅极结构形成在有源层的第一区域上。 间隔物形成在有源层的第二区域上，并与门结构的侧壁接触。 源极/漏极层与有源层的第二区域相邻。

公开(公告)号：US20140357821A1

公开(公告)日：2014-12-04

申请号：US14356483

申请日：2012-08-27

Applicant: Shaochun Zhao ,  Jun Lan ,  Jianxin Zhang ,  Bin Liu ,  Bin Li ,  Jiayong Gao ,  Xianrong Wang

Inventor： Shaochun Zhao ,  Jun Lan ,  Jianxin Zhang ,  Bin Liu ,  Bin Li ,  Jiayong Gao ,  Xianrong Wang

IPC: C08F214/22

CPC classification number: C08F214/222 ,  C08F2/24 ,  C08F2/38 ,  C08F214/22 ,  C08F216/1408 ,  C08F2500/21 ,  C08F2800/10

Abstract: The present invention provides a low-temperature-resistant fluorine-containing elastomer formed through polymerization of the comonomers: 40-80 mol % 1,1-vinylidene fluoride, 2-10 mol % tetrafluoroethylene, 10-30 mol % perfluoro(alkyl vinyl ether), and 1-10 mol % vulcanization monomer. The present invention further provides a preparation method of the fluorine-containing elastomer. In the present invention, on basis of a large number of experiments, the contents of the comonomers of the fluorine-containing elastomer are adjusted, so that the low temperature performance thereof is significantly improved, and the low-temperature retraction temperature TR-10

Abstract translation: 本发明提供通过共聚单体的聚合形成的低温耐氟性弹性体：40〜80摩尔％1,1-偏二氟乙烯，2-10摩尔％四氟乙烯，10〜30摩尔％全氟（烷基乙烯基醚 ）和1-10摩尔％的硫化单体。 本发明还提供了含氟弹性体的制备方法。 在本发明中，在大量实验的基础上，调整含氟弹性体的共聚单体的含量，使其低温性能显着提高，低温回收温度TR-10 < -40。 此外，含氟弹性体在甲醇中的体积变化率降低，耐油性和耐溶剂性提高，从而提高含氟弹性体的耐油性能和耐溶剂性能。

公开(公告)号：US20140187529A1

公开(公告)日：2014-07-03

申请号：US14001936

申请日：2012-02-29

Applicant: Rupa S. Shetty ,  Martha J. Kelly ,  Bin Liu ,  Jinming Zou ,  Kristopher K. Moffett ,  Younghee Lee

Inventor： Rupa S. Shetty ,  Kevin J. Moriarity ,  Martha J. Kelly ,  Bin Liu ,  Jinming Zou ,  Kristopher K. Moffett ,  Younghee Lee

IPC: C07D413/14 ,  C07D401/12 ,  C07D401/14

CPC classification number: C07D413/14 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D407/14 ,  C07D409/14 ,  C07D417/14 ,  C07D487/04 ,  C07D491/056

Abstract: A compound of formula (I): wherein all symbols have the same meanings as defined in the specification; a salt thereof, a solvate thereof, an N-oxide thereof, or a prodrug thereof, has an Itk inhibitory activity, and is useful as a method for preventing and/or treating atopic dermatitis, and the like.

Abstract translation: 式（I）的化合物：其中所有符号具有与说明书中定义的相同的含义; 其盐，其溶剂合物，N-氧化物或其前药具有Itk抑制活性，可用作预防和/或治疗特应性皮炎等的方法。