Pharmaceutical Preparations And Medicines Capable Of Generating, And/Or Containing, Thrombin
    81.
    发明申请
    Pharmaceutical Preparations And Medicines Capable Of Generating, And/Or Containing, Thrombin 审中-公开
    可生产和/或含有凝血酶的药物制剂和药物

    公开(公告)号:US20090123453A1

    公开(公告)日:2009-05-14

    申请号:US12355507

    申请日:2009-01-16

    申请人: Johann Eibl

    发明人: Johann Eibl

    IPC分类号: A61K38/48

    摘要: The invention relates to a pharmaceutical active ingredient preparation for producing a medicament that contains thrombin or has a thrombin-generating capacity and compositions comprising thereof. The inventive preparation contains: (A) prothrombin obtained from plasma or by means of genetic engineering (coagulation factor II), (B) coagulation factors V, VIII, IX, X obtained from plasma or by means of genetic engineering, which can be at least partially in the activated state, and coagulation factor X1a obtained from plasma or by means of genetic engineering, and (C) phospholipids which are safe from prions and contribute to the clotting process, said phospholipids being optionally contained in liposomes.

    摘要翻译: 本发明涉及一种用于生产含有凝血酶或具有凝血酶生成能力的药物的药物活性成分制剂及其组合物。 本发明的制剂包含:(A)从血浆或通过基因工程(凝血因子II)获得的凝血酶原,(B)从血浆或通过遗传工程获得的凝血因子V,VIII,IX,X,其可以在 至少部分处于活化状态,以及从血浆或通过遗传工程获得的凝血因子X1a,和(C)磷酸,其从朊病毒中是安全的并且有助于凝血过程,所述磷脂任选地包含在脂质体中。

    Immunoglobulin-G-containing fraction
    89.
    发明授权
    Immunoglobulin-G-containing fraction 失效
    含有免疫球蛋白的G含量

    公开(公告)号:US5122373A

    公开(公告)日:1992-06-16

    申请号:US569535

    申请日:1990-08-20

    CPC分类号: C07K16/065 A61K38/00

    摘要: An immunoglobulin-G-containing fraction from human or animal plasma comprising monomeric IgG molecules as well as at least 70% gammaglobulins, destined for intravenous application.The fraction has a low anticomplementary activity and is substantially free of vasoactive and leucopenically active as well as bronchospastic substances.

    摘要翻译: 来自人或动物血浆的含有免疫球蛋白G的级分包含单体IgG分子以及至少70%的用于静脉内应用的丙种球蛋白。 所述级分具有低抗补体活性,并且基本上不含血管活性和有丝分裂活性物质以及支气管痉挛物质。

    Light emitting diode chip
    90.
    发明授权
    Light emitting diode chip 有权
    发光二极管芯片

    公开(公告)号:US08872209B2

    公开(公告)日:2014-10-28

    申请号:US13581417

    申请日:2011-02-15

    摘要: A light emitting diode chip includes a semiconductor layer sequence, the semiconductor layer sequence having an active layer that generates electromagnetic radiation, wherein the light emitting diode chip has a radiation exit area at a front side. At a rear side lying opposite the radiation exit area, the light emitting diode chip has, at least in regions, a mirror layer containing silver. A functional layer that reduces corrosion and/or improves adhesion of the mirror layer is arranged on the mirror layer, wherein a material from which the functional layer is formed is also distributed in the entire mirror layer. The material of the functional layer has a concentration gradient in the mirror layer, wherein the concentration of the material of the functional layer in the mirror layer decreases proceeding from the functional layer in the direction toward the semiconductor layer sequence.

    摘要翻译: 发光二极管芯片包括半导体层序列,所述半导体层序列具有产生电磁辐射的有源层,其中所述发光二极管芯片在前侧具有辐射出射区域。 在与辐射出口区域相对的后侧,发光二极管芯片至少在区域中具有含有银的镜面层。 降低镜面层的腐蚀和/或改善粘合性的功能层被布置在镜面层上,其中形成功能层的材料也分布在整个镜面层中。 功能层的材料在镜面层中具有浓度梯度,其中镜面层中的功能层的材料的浓度从功能层朝向半导体层序列的方向减小。