-
公开(公告)号：US20080241927A1
公开(公告)日：2008-10-02
申请号：US12052868
申请日：2008-03-21
申请人： Linda A. Castle , Dan Siehl , Lorraine Giver , Jeremy Minshull , Christina Ivy , Yong Hong Chen , Phillip A. Patten , Rebecca Gorton , Nicholas B. Duck , Billy Fred McCutchen , Roger Kemble
发明人： Linda A. Castle , Dan Siehl , Lorraine Giver , Jeremy Minshull , Christina Ivy , Yong Hong Chen , Phillip A. Patten , Rebecca Gorton , Nicholas B. Duck , Billy Fred McCutchen , Roger Kemble
CPC分类号： C12N9/1029 , C12N15/8275
摘要： Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
摘要翻译： 本文提供了新的蛋白质，包括能够催化草甘膦和其他结构相关蛋白质的乙酰化的蛋白质。 还提供了能够编码这些蛋白质的新型多核苷酸，包含这些新蛋白质和/或多核苷酸中的一种或多种的组合物，包含这些新化合物的重组细胞和转基因植物，涉及新化合物的多样化方法，以及使用该化合物的方法。 本文提供的一些新颖的方法和化合物可以用于产生对草甘膦有抗性的生物，如植物。
-
82.发明申请公开(公告)号：US20080133143A1
公开(公告)日：2008-06-05
申请号：US11981577
申请日：2007-10-30
申请人： Claes Gustafsson , Sridhar Govindarajan , Robin A. Emig , Richard John Fox , Ajoy K. Roy , Jeremy S. Minshull , S. Christopher Davis , Anthony R. Cox , Phillip A. Patten , Linda A. Castle , Daniel L. Siehl , Rebecca Lynne Gorton , Teddy Chen
发明人： Claes Gustafsson , Sridhar Govindarajan , Robin A. Emig , Richard John Fox , Ajoy K. Roy , Jeremy S. Minshull , S. Christopher Davis , Anthony R. Cox , Phillip A. Patten , Linda A. Castle , Daniel L. Siehl , Rebecca Lynne Gorton , Teddy Chen
IPC分类号： G01N33/68
摘要： The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.
摘要翻译： 本发明一般涉及快速有效地搜索生物相关数据空间的方法。 更具体地，本发明包括从复杂的生物分子文库或这些文库集合鉴定具有所需性质或最适合于获得这些性质的生物分子的方法。 本发明还提供了对序列活性关系建模的方法。 由于许多方法是计算机实现的，本发明另外提供用于执行这些方法的数字系统和软件。
-
公开(公告)号：US06613514B2
公开(公告)日：2003-09-02
申请号：US09559671
申请日：2000-04-27
IPC分类号： C12Q168
CPC分类号： C12N15/1031 , A61K38/45 , A61K48/00 , C07K14/43595 , C07K14/545 , C07K14/56 , C07K16/00 , C07K2317/565 , C07K2317/622 , C12N7/00 , C12N9/0069 , C12N9/1007 , C12N9/16 , C12N9/86 , C12N15/10 , C12N15/1027 , C12N15/1034 , C12N15/1037 , C12N15/1058 , C12N15/52 , C12N15/64 , C12N15/67 , C12N2795/14043 , C12N2795/14143 , C12Q1/6811 , C12Q1/6853 , C12Q1/686 , C40B40/02 , C40B40/08 , C40B50/06 , G01N33/68 , G01N33/6845
摘要： Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
-
公开(公告)号：US06579678B1
公开(公告)日：2003-06-17
申请号：US09693350
申请日：2000-10-20
IPC分类号： C12Q168
CPC分类号： C12N15/1031 , A61K38/45 , A61K48/00 , C07K14/43595 , C07K14/545 , C07K14/56 , C07K16/00 , C07K2317/565 , C07K2317/622 , C12N7/00 , C12N9/0069 , C12N9/1007 , C12N9/16 , C12N9/86 , C12N15/10 , C12N15/1027 , C12N15/1034 , C12N15/1037 , C12N15/1058 , C12N15/52 , C12N15/64 , C12N15/67 , C12N2795/14043 , C12N2795/14143 , C12Q1/6811 , C12Q1/6853 , C12Q1/686 , C40B40/02 , C40B40/08 , C40B50/06 , G01N33/68 , G01N33/6845
摘要： Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
-
公开(公告)号：US06426224B1
公开(公告)日：2002-07-30
申请号：US09626528
申请日：2000-07-27
申请人： Andreas Crameri , Willem P. C. Stemmer , Jeremy Minshull , Steven H. Bass , Mark Welch , Jon E. Ness , Claes Gustafsson , Phillip A. Patten
发明人： Andreas Crameri , Willem P. C. Stemmer , Jeremy Minshull , Steven H. Bass , Mark Welch , Jon E. Ness , Claes Gustafsson , Phillip A. Patten
IPC分类号： C12N1500
CPC分类号： C12N15/11 , A61K39/00 , B01J2219/00689 , C07K14/005 , C07K14/505 , C07K14/535 , C12N9/16 , C12N15/1031 , C12N15/1034 , C12N2740/16122
摘要： Methods of recombining nucleic acids, including homologous nucleic acids, are provided. Families of gene shuffling oligonucleotides and their use in recombination procedures, as well as polymerase and ligase mediated recombination methods are also provided.
摘要翻译： 提供重组核酸的方法，包括同源核酸。 还提供了基因改组寡核苷酸家族及其在重组过程中的应用，以及聚合酶和连接酶介导的重组方法。
-
公开(公告)号：US06406910B1
公开(公告)日：2002-06-18
申请号：US09723424
申请日：2000-11-27
IPC分类号： C12N1500
CPC分类号： C12N15/8274 , C12N15/10 , C12N15/1027 , C12N15/8216 , C12N15/8289 , Y10T436/143333
摘要： Methods of modulating, tuning and improving hybridization properties and recombination properties of molecules for use in nucleic acid shuffling procedures, relates recombination mixtures and methods of modulating, tuning, improving and evolving splicing of RNAs and proteins are provided.
-
公开(公告)号：US06406855B1
公开(公告)日：2002-06-18
申请号：US09717419
申请日：2000-11-22
IPC分类号： C12Q168
CPC分类号： C40B40/02 , C07K14/43595 , C07K14/545 , C07K14/56 , C07K16/00 , C07K2317/565 , C07K2317/622 , C12N9/0069 , C12N9/86 , C12N15/1034 , C12N15/1037 , C12N15/52 , C12N15/64 , G01N33/68
摘要： Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
摘要翻译： 提供了用于工业和医药兴趣蛋白质进化的方法，包括进行重组和选择的方法。 还公开了通过这些方法制备的组合物。
-
公开(公告)号：US06355484B1
公开(公告)日：2002-03-12
申请号：US09344002
申请日：1999-06-24
IPC分类号： C12N1500
CPC分类号： C12N15/1031 , A61K38/45 , A61K48/00 , C07K14/43595 , C07K14/545 , C07K14/56 , C07K16/00 , C07K2317/565 , C07K2317/622 , C12N7/00 , C12N9/0069 , C12N9/1007 , C12N9/16 , C12N9/86 , C12N15/10 , C12N15/1027 , C12N15/1034 , C12N15/1037 , C12N15/1058 , C12N15/52 , C12N15/64 , C12N15/67 , C12N2795/14043 , C12N2795/14143 , C12Q1/6811 , C12Q1/6853 , C12Q1/686 , C40B40/02 , C40B40/08 , C40B50/06 , G01N33/68 , G01N33/6845
摘要： Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
摘要翻译： 提供了用于工业和医药兴趣蛋白质进化的方法，包括进行重组和选择的方法。 还公开了通过这些方法制备的组合物。
-
89.发明授权公开(公告)号：US08849575B2
公开(公告)日：2014-09-30
申请号：US11429628
申请日：2006-05-05
申请人： Claes Gustafsson , Sridhar Govindarajan , Robin A. Emig , Richard John Fox , Ajoy K. Roy , Jeremy S. Minshull , S. Christopher Davis , Anthony R. Cox , Phillip A. Patten , Linda A. Castle , Daniel L. Siehl , Rebecca Lynne Gorton , Teddy Chen
发明人： Claes Gustafsson , Sridhar Govindarajan , Robin A. Emig , Richard John Fox , Ajoy K. Roy , Jeremy S. Minshull , S. Christopher Davis , Anthony R. Cox , Phillip A. Patten , Linda A. Castle , Daniel L. Siehl , Rebecca Lynne Gorton , Teddy Chen
摘要： The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.
摘要翻译： 本发明一般涉及快速有效地搜索生物相关数据空间的方法。 更具体地，本发明包括从复杂的生物分子文库或这些文库集合鉴定具有所需性质或最适合于获得这些性质的生物分子的方法。 本发明还提供了对序列活性关系建模的方法。 由于许多方法是计算机实现的，本发明另外提供用于执行这些方法的数字系统和软件。
-
公开(公告)号：US20130102765A9
公开(公告)日：2013-04-25
申请号：US13489008
申请日：2012-06-05
申请人： Linda A. Castle , Dan Siehl , Lorraine Giver , Jeremy Minshull , Christina Ivy , Yong Hong Chen , Phillip A. Patten , Rebecca Gorton , Nicholas B. Duck , Billy Fred McCutchen , Roger Kemble
发明人： Linda A. Castle , Dan Siehl , Lorraine Giver , Jeremy Minshull , Christina Ivy , Yong Hong Chen , Phillip A. Patten , Rebecca Gorton , Nicholas B. Duck , Billy Fred McCutchen , Roger Kemble
IPC分类号： C12N15/54
CPC分类号： C12N9/1029 , C12N15/8275
摘要： Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
-
-
-
-
-
-
-
-
-
搜索结果
110 条记录 (耗时 0.077 秒)
