公开(公告)号：US20060282804A1

公开(公告)日：2006-12-14

申请号：US11458345

申请日：2006-07-18

申请人： Chew Hoe Ang ,  Gang Chen ,  Shyue Seng Tan

发明人： Chew Hoe Ang ,  Gang Chen ,  Shyue Seng Tan

IPC分类号： G06F17/50

CPC分类号： H01L22/34 ,  G01R31/2628 ,  G01R31/2642 ,  H01L2924/0002 ,  H01L2924/00

摘要： The invention describes a novel test structure and process to create the structure for performing automatic dynamic stress testing of PMOS devices for Negative Bias Temperature Instability (NB TI). The invention consists of an integrated inverter, two integrated electronic switches for switching from stress mode to device DC characterization measurement mode, and a PMOS FET device under test (DUT). The inverter assures the proper 180 degree phase relationship between the test device source and gate voltage while the imbedded electronic switches provide isolation of the test device during DC characterization testing. Another embodiment of the invention enables the testing of multiple devices under test (DUTs).

摘要翻译： 本发明描述了一种新颖的测试结构和工艺，以创建用于负偏压温度不稳定（NB TI）的PMOS器件的自动动态应力测试的结构。 本发明由集成逆变器，用于从应力模式切换到器件直流表征测量模式的两个集成电子开关以及被测试的PMOS FET器件（DUT）组成。 在DC特性测试期间，嵌入式电子开关提供测试设备的隔离，逆变器确保测试设备源和栅极电压之间正确的180度相位关系。 本发明的另一实施例使得能够测试被测试的多个器件（DUT）。

公开(公告)号：US20060263331A1

公开(公告)日：2006-11-23

申请号：US10741161

申请日：2003-12-19

申请人： Gang Chen ,  Xinjiang Du ,  Dezheng Wu ,  Weijing Zhang ,  Shirley Chen

发明人： Gang Chen ,  Xinjiang Du ,  Dezheng Wu ,  Weijing Zhang ,  Shirley Chen

IPC分类号： A61K38/19 ,  A61K38/17 ,  A61K31/704 ,  A61K31/522 ,  A61K33/24

CPC分类号： A61K45/06 ,  A61K38/1816 ,  A61K38/191 ,  A61K38/193 ,  A61K38/2013 ,  A61K38/2026 ,  A61K38/208 ,  A61K38/21 ,  A61K2300/00

摘要： Improved methods for treating neoplastic diseases such as cancer are provided by using muteins of human tumor necrosis factor-alpha (TNF-α). Compared to wild-type human TNF-α these therapeutic TNF muteins have higher specific anti-tumor activity, but with much reduced systemic toxicity and milder side effects such chills and fever. In addition, potentially synergistic, novel combinations of the inventive TNF-α muteins with other anti-neoplastic agents are provided for effectively treating patients having particular types of cancer or malignancy or at particular stages of cancer development, and for mitigating resistance of the patients to treatment of non-TNF antineoplastic agents.

摘要翻译： 通过使用人肿瘤坏死因子-α（TNF-α）的突变蛋白来提供治疗肿瘤疾病如癌症的改进方法。 与野生型人TNF-α相比，这些治疗性TNF突变蛋白具有更高的特异性抗肿瘤活性，但是具有大大降低的全身毒性和较轻的副作用，如发冷和发烧。 另外，提供本发明的TNF-α突变蛋白与其它抗肿瘤剂的潜在协同，新颖的组合，用于有效治疗具有特定类型的癌症或恶性肿瘤或癌症发展的特定阶段的患者，并且为了减轻患者的耐药性 治疗非TNF抗肿瘤药物。

公开(公告)号：US20060208223A1

公开(公告)日：2006-09-21

申请号：US11402693

申请日：2006-04-11

申请人： Gang Chen ,  Dan Fuchs ,  Ylva Olsson ,  Ronen Rapaport ,  Vlkram Sundar

发明人： Gang Chen ,  Dan Fuchs ,  Ylva Olsson ,  Ronen Rapaport ,  Vlkram Sundar

IPC分类号： G02B6/00 ,  G02B6/10

CPC分类号： B82Y15/00 ,  B82Y20/00 ,  B82Y30/00 ,  G02B1/04 ,  G02B1/045 ,  G02B6/138 ,  G02B2006/12097 ,  C08L27/12

摘要： The present invention relates to a polymeric composition of matter. The composition includes at least one polymer matrix and plurality of quantum dots distributed therein. The polymer may be a perfluorocyclobutane polymer having high optical transmission at telecommunications wavelengths. The quantum dots may include cap compounds to increase the solubility of the quantum dots in the composition. Typical cap compounds include aromatic organic molecules. Optical devices including waveguides may be fabricated from the polymeric compositions of the invention.

公开(公告)号：US20060070050A1

公开(公告)日：2006-03-30

申请号：US10954586

申请日：2004-09-30

申请人： Gang Chen

发明人： Gang Chen

IPC分类号： G06F9/45

CPC分类号： G06F8/433 ,  G06F8/443

摘要： A method and apparatus for reducing instruction dependencies in extended SSA form instructions includes examining a first instruction of a worklist, wherein the worklist contains instructions in the extended SSA form that have a source, a previous link and a write mask and further produce an output. The method and apparatus further includes examining at least one second instruction of the worklist, wherein at least one second instruction is a source of the first instruction. Lastly, the method and apparatus includes translating the plurality of instructions in the worklist into a second plurality of instructions in the extended SSA form where the second plurality of instructions contains less instruction dependencies such as previous links.

摘要翻译： 用于减少扩展SSA形式指令中的指令依赖性的方法和装置包括检查工作列表的第一指令，其中工作列表包含具有源，先前链接和写掩码的扩展SSA形式的指令，并进一步产生输出。 该方法和装置还包括检查工作列表的至少一个第二指令，其中至少一个第二指令是第一指令的源。 最后，所述方法和装置包括将工作列表中的多个指令转换成扩展SSA形式的第二多个指令，其中第二多个指令包含较少的指令依赖性，例如先前的链接。

公开(公告)号：US20050186623A1

公开(公告)日：2005-08-25

申请号：US11099158

申请日：2005-04-05

申请人： James Fandl ,  Neil Stahl ,  Gang Chen ,  George Yancopoulos

发明人： James Fandl ,  Neil Stahl ,  Gang Chen ,  George Yancopoulos

IPC分类号： A01K67/027 ,  C07K14/315 ,  C07K14/52 ,  C07K16/28 ,  C12N5/10 ,  C12N15/09 ,  C40B30/04 ,  G01N33/569 ,  G01N33/68 ,  C12Q1/68 ,  G01N33/53 ,  G01N33/567

CPC分类号： C40B30/04 ,  A01K2217/05 ,  A01K2267/01 ,  C07K14/315 ,  C07K14/52 ,  C07K16/2863 ,  C07K2317/77 ,  C07K2319/00 ,  C12N15/1051 ,  G01N33/56966 ,  G01N33/6845 ,  G01N2500/10

摘要： A method for identifying and isolating cells which produce secreted proteins. This method is based upon a specific characteristic or the expression level of the secreted protein by transiently capturing the secreted protein on the surface of an individual cell, allowing selection of rare cell clones from a heterogeneous population. Also provided is the use of this method to generate cells which produce a desired level of secreted protein or secreted protein of a particular characteristic(s), and organisms which possess such cells. In particular, the method allows rapid isolation of high expression recombinant antibody-producing cell lines, or may be applied directly to rapid isolation of specific hybridomas, or to the isolation of antibody-producing transgenic animals. This method is applicable for any cell which secretes protein.

公开(公告)号：US20050111510A1

公开(公告)日：2005-05-26

申请号：US10719072

申请日：2003-11-21

申请人： Mali Gong ,  Chen Li ,  Qiang Liu ,  Ping Yan ,  Gang Chen ,  HaiTao Zhang ,  Ruizhen Cui

发明人： Mali Gong ,  Chen Li ,  Qiang Liu ,  Ping Yan ,  Gang Chen ,  HaiTao Zhang ,  Ruizhen Cui

IPC分类号： H01S3/042 ,  H01S3/06 ,  H01S3/09 ,  H01S3/0941 ,  H01S3/16

CPC分类号： H01S3/0606 ,  H01S3/042 ,  H01S3/0615 ,  H01S3/08095 ,  H01S3/094057 ,  H01S3/0941 ,  H01S3/1611 ,  H01S3/1643 ,  H01S3/2316

摘要： A corner-pumping method for slab laser and a solid-state laser gain module are disclosed. In one embodiment, said method comprises directing a pump light into a laser slab through slab corners of said laser slab; propagating the pump light within the laser slab by total internal reflection (TIR); and substantially absorbing the pump light during propagating. In another embodiment, said gain module comprises a laser slab formed by a solid state laser material, said laser slab including slab corners with corner faces; and a pump source providing a pump light; wherein said pump light is directed into said laser slab through said slab corners of said laser slab, propagated within said laser slab by total internal reflection (TIR), and substantially absorbed during propagation; and wherein said laser slab outputs an amplified laser beam.

摘要翻译： 公开了一种用于平板激光器和固态激光增益模块的角式抽取方法。 在一个实施例中，所述方法包括将泵浦光通过所述激光板的板角引导到激光板中; 通过全内反射（TIR）传播激光板内的泵浦光; 并且在传播期间基本上吸收泵浦光。 在另一个实施例中，所述增益模块包括由固体激光材料形成的激光平板，所述激光板包括具有角面的平板角; 以及提供泵浦光的泵浦源; 其中所述泵浦光通过所述激光板的所述板角转入所述激光板，通过全内反射（TIR）在所述激光板内传播，并且在传播期间基本上被吸收; 并且其中所述激光板输出放大的激光束。

公开(公告)号：US06553932B2

公开(公告)日：2003-04-29

申请号：US09853397

申请日：2001-05-11

申请人： Kuo-Shih Liu ,  Ramana Veerasingam ,  Zhi Xu ,  Ping Xu ,  Mario Dave Silvetti ,  Gang Chen

发明人： Kuo-Shih Liu ,  Ramana Veerasingam ,  Zhi Xu ,  Ping Xu ,  Mario Dave Silvetti ,  Gang Chen

IPC分类号： C23C1600

CPC分类号： C23C16/45565 ,  C23C16/45591 ,  C23C16/509 ,  H01J37/3244 ,  H01J37/32623 ,  H01J37/32642 ,  H01J37/32935

摘要： An appparatus for confining plasma within a process zone of a substrate processing chamber. In one aspect, an apparatus comprises an annular member having an upper mounting surface, an inner confinement wall, and an outer confinement wall. The apparatus is disposed on or otherwise connected to a gas distribution assembly of the processing chamber to prevent plasma edge effects on the surface of a substrate. The apparatus provides a plasma choke aperture that reduces the volume of the process zone around the periphery of the substrate thereby eliminating uneven deposition of material around the edge of the substrate.

摘要翻译： 一种用于将等离子体限制在衬底处理室的处理区内的设备。 一方面，一种装置包括具有上安装表面，内限制壁和外约束壁的环形构件。 该设备设置在处理室的气体分配组件上或以其他方式连接到处理室的气体分配组件，以防止等离子体对基板表面的影响。 该装置提供等离子体扼流圈，其减小了基板周边周围处理区的体积，从而消除了材料在基板边缘周围的不均匀沉积。

公开(公告)号：US06351956B1

公开(公告)日：2002-03-05

申请号：US09466587

申请日：1999-12-17

申请人： Gang Chen ,  James R Tamm ,  Dewane C Cogswell

发明人： Gang Chen ,  James R Tamm ,  Dewane C Cogswell

IPC分类号： F25B4902

CPC分类号： B60H1/3225 ,  F25B49/022

摘要： A compressor control system and method are provided for a vehicle air conditioner. The control device controls engagement of a compressor clutch member at engine start-up to discharge liquid refrigerant from the compressor. The control system provides for disengagement of the clutch member if the detected operating conditions are indicative of compressor lock-up without the use of a dedicated compressor lock-up sensor.

摘要翻译： 提供一种用于车辆空调的压缩机控制系统和方法。 控制装置控制发动机启动时的压缩机离合器构件的接合，以从压缩机排出液体制冷剂。 如果检测到的操作条件指示压缩机锁定而不使用专用压缩机锁定传感器，则控制系统提供离合器构件的分离。

公开(公告)号：US06347175B1

公开(公告)日：2002-02-12

申请号：US09354361

申请日：1999-07-14

申请人： Gang Chen ,  Lyle David Kinney ,  Emmanuel C Onyiriuka ,  Mike Xu Ouyang ,  Laura Weller-Brophy

发明人： Gang Chen ,  Lyle David Kinney ,  Emmanuel C Onyiriuka ,  Mike Xu Ouyang ,  Laura Weller-Brophy

IPC分类号： G02B602

CPC分类号： G02B6/02204 ,  C03C17/09 ,  C03C25/22 ,  C03C25/226 ,  C03C25/46 ,  C03C2217/27 ,  C23C14/18 ,  C23C14/22 ,  G02B6/4248

摘要： A copper-gallium alloy is deposited on a nonconductive substrate, such as glass, ceramic, or polymeric material, to provide a conductor to which solder will readily adhere, such that electrical contacts to photonic and electrical components can be made. The copper-gallium thin film can also be used to provide a surface for solder sealing a component within a hermetically sealed enclosure. In a preferred embodiment, the copper-gallium alloy was from about 1 to about 40 percent gallium to about 99 to about 60 percent copper and was deposited to a thickness of from about 400 nanometers to about 3 microns. The copper-gallium film is deposited utilizing sputtering or electron beam deposition equipment.

摘要翻译： 铜 - 镓合金沉积在诸如玻璃，陶瓷或聚合物材料的非导电基底上，以提供导体，焊料将容易地粘附到该导体上，使得可以制造与光子和电气部件的电接触。 铜镓薄膜也可用于提供用于焊接密封密封外壳内的部件的表面。 在优选的实施方案中，铜 - 镓合金是约1-约40％的镓 - 约99-约60％的铜，并沉积到约400纳米至约3微米的厚度。 使用溅射或电子束沉积设备沉积铜 - 镓膜。

公开(公告)号：US06286366B1

公开(公告)日：2001-09-11

申请号：US09189719

申请日：1998-11-11

申请人： Gang Chen ,  Zhijian James Wu ,  Anson Lee ,  Kerry D. Franks ,  Timothy L. McDonald ,  James R. Tamm

发明人： Gang Chen ,  Zhijian James Wu ,  Anson Lee ,  Kerry D. Franks ,  Timothy L. McDonald ,  James R. Tamm

IPC分类号： G01L326

CPC分类号： F02D41/32 ,  F02D41/0065 ,  F02D2200/0406 ,  F02D2200/0414

摘要： A technique for determining the charge air temperature within an intake manifold of an internal combustion engine of a vehicle without using a dedicated temperature sensor. The technique includes identifying a non-linear dynamic model based on the physical concepts of thermal transfer and system identification technique. The charge air temperature model uses several available physical measurements from the vehicle, including inlet air temperature, engine coolant temperature, vehicle speed, manifold pressure, engine speed, exhaust gas recirculation condition, and the engine fan on/off state. The model parameters are determined based on specific vehicle characteristics, and collected data from the vehicle. The charge air temperature is predicted by the model at regular predetermined intervals from the physical measurements, the vehicle parameters and the charge air temperature from the previous time. An estimation of an initial charge air temperature when the vehicle is turned on can be obtained based on the available temperature sensor readings when vehicle is turned on and stored data of the charge temperature, and all the measured temperature readings just before the engine was turned off.

摘要翻译： 一种用于在不使用专用温度传感器的情况下确定车辆内燃机的进气歧管内的增压空气温度的技术。 该技术包括基于热传递和系统识别技术的物理概念识别非线性动态模型。 增压空气温度模型使用来自车辆的几种可用的物理测量，包括入口空气温度，发动机冷却剂温度，车辆速度，歧管压力，发动机速度，废气再循环状况和发动机风扇开/关状态。 模型参数根据特定车辆特性确定，并从车辆收集数据。 从物理测量，车辆参数和前一次的增压空气温度以规定的预定间隔，模型预测增压空气温度。 可以基于车辆开启时可用的温度传感器读数和存储充电温度的数据以及在发动机关闭之前的所有测量温度读数来获得车辆接通时的初始增压空气温度的估计 。