公开(公告)号：US20140172033A1

公开(公告)日：2014-06-19

申请号：US14186317

申请日：2014-02-21

申请人： PACESETTER, INC.

发明人： Xing Pei ,  Paul A. Levine

IPC分类号： A61N1/362

CPC分类号： A61N1/3621 ,  A61B5/0422 ,  A61B5/044 ,  A61B5/0452 ,  A61N1/36507 ,  A61N1/36521 ,  A61N1/37211

摘要： An implantable medical device is provided for detecting transportless ventricular rhythm of a heart lacking atrial transport and comprises a housing, sensors configured to be located proximate to a heart, a sensing module to sense cardiac signals representative of a rhythm originating from the heart and a rhythm detection module. The rhythm detection module determines a change in AV association and identifies a potential ventricular complex with loss of atrial transport (VCLAT) based on the change in AV association.

摘要翻译： 提供了一种可植入医疗装置，用于检测缺乏心房输送的心脏的无运动心室节律，并且包括壳体，被配置为邻近心脏定位的传感器，感测模块，用于感测代表源自心脏的节律的心脏信号和节律 检测模块。 节律检测模块确定AV关联的变化，并且基于AV关联的变化来识别具有心房传播丧失（VCLAT）的潜在心室复合物。

公开(公告)号：US20140148867A1

公开(公告)日：2014-05-29

申请号：US13686359

申请日：2012-11-27

申请人： MEDTRONIC, INC.

发明人： Todd M. Zielinski ,  Douglas A. Hettrick ,  Yong K. Cho ,  Eduardo N. Warman ,  Paul A. Sobotka

IPC分类号： A61N1/365 ,  A61M27/00

CPC分类号： A61N1/36507 ,  A61B5/0537 ,  A61B5/085 ,  A61M27/00 ,  A61N1/3627 ,  A61N1/36521

摘要： A medical device and associated method for delivery of a cardiac therapy that includes determining a first impedance signal along a thoracic electrode vector extending within a portion of a thoracic cavity, determining a second impedance signal along an extra-thoracic electrode vector extending outside the thoracic cavity, comparing first amplitude measurements corresponding to the first impedance signals and second amplitude measurements corresponding to the second impedance signals, comparing first slope measurements corresponding to the first impedance signals and second slope measurements corresponding to the second impedance signals, and determining delivery of the cardiac therapy in response to the comparing.

摘要翻译： 一种用于递送心脏疗法的医疗装置和相关联的方法，其包括沿着在胸腔的一部分内延伸的胸部电极矢量确定第一阻抗信号，沿着延伸到胸腔外部的胸外电极矢量确定第二阻抗信号 比较对应于第一阻抗信号的第一振幅测量值和对应于第二阻抗信号的第二振幅测量值，比较对应于第一阻抗信号的第一斜率测量值和对应于第二阻抗信号的第二斜率测量值，以及确定心脏治疗 响应比较。

公开(公告)号：US20140135637A1

公开(公告)日：2014-05-15

申请号：US14162218

申请日：2014-01-23

申请人： Cardiac Pacemakers, Inc.

发明人： Gust Bardy

IPC分类号： A61B5/0402 ,  A61B5/00

CPC分类号： A61B5/0402 ,  A61B5/0006 ,  A61B5/02 ,  A61B5/0205 ,  A61B5/0215 ,  A61B5/02438 ,  A61B5/029 ,  A61B5/0452 ,  A61B5/046 ,  A61B5/0472 ,  A61B5/486 ,  A61N1/36507 ,  G06F19/324 ,  G06F19/3418 ,  G06F19/3481 ,  G16H10/60 ,  G16H15/00 ,  G16H50/20

摘要： A system and method for automated diagnosis of myocardial ischemia through remote monitoring is described. Physiological measures comprising data either recorded on a regular basis by a medical device or derived therefrom is stored. Qualitative measures associated with the physiological measures are matched. Indications of myocardial ischemia are remotely identified. The qualitative measures for both of a reduction in exercise capacity and respiratory distress occurring contemporaneously are examined. The qualitative measures for angina that accompanies the reduction in exercise capacity and the respiratory distress are evaluated. A time course for each of the indications is determined. A patient status is formed comprising an onset of myocardial ischemia conditioned on the time course comprising a short duration.

摘要翻译： 描述了通过远程监控自动诊断心肌缺血的系统和方法。 存储包括由医疗装置定期记录或由其导出的数据的生理测量。 与生理措施相关的定性措施相匹配。 远端识别心肌缺血症状。 检查同时发生运动能力和呼吸窘迫的降低的定性措施。 评估伴随降低运动能力和呼吸窘迫的心绞痛的定性措施。 确定每个指示的时间过程。 形成患者状态，其包括在包括短持续时间的时间过程中调节的心肌缺血发作。

公开(公告)号：US08694082B2

公开(公告)日：2014-04-08

申请号：US12727130

申请日：2010-03-18

申请人： Xing Pei ,  Paul A. Levine

发明人： Xing Pei ,  Paul A. Levine

IPC分类号： A61B5/0452

CPC分类号： A61N1/3621 ,  A61B5/0422 ,  A61B5/044 ,  A61B5/0452 ,  A61N1/36507 ,  A61N1/36521 ,  A61N1/37211

摘要： An implantable medical device is provided for detecting transportless ventricular rhythm of a heart lacking atrial transport and comprises a housing, sensors configured to be located proximate to a heart, a sensing module to sense cardiac signals representative of a rhythm originating from the heart and a rhythm detection module. The rhythm detection module determines a change in AV association and identifies a potential ventricular complex with loss of atrial transport (VCLAT) based on the change in AV association.

摘要翻译： 提供了一种可植入医疗装置，用于检测缺乏心房输送的心脏的无运动心室节律，并且包括壳体，被配置为邻近心脏定位的传感器，感测模块，用于感测代表源自心脏的节律的心脏信号和节律 检测模块。 节律检测模块基于AV关联的变化来确定AV关联的变化并识别具有心房传播丧失（VCLAT）的潜在心室复合体。

公开(公告)号：US20130304149A1

公开(公告)日：2013-11-14

申请号：US13884144

申请日：2011-11-08

申请人： David Kass ,  Gordon Tomaselli ,  Jonathan Kirk

发明人： David Kass ,  Gordon Tomaselli ,  Jonathan Kirk

IPC分类号： A61N1/365 ,  G01N27/447 ,  C12Q1/68

CPC分类号： A61N1/3627 ,  A61N1/365 ,  A61N1/36507 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3688 ,  C12Q1/6876 ,  G01N27/447

摘要： The invention provides methods related to improving heart function.

摘要翻译： 本发明提供了改善心脏功能的方法。

公开(公告)号：US08478407B2

公开(公告)日：2013-07-02

申请号：US13192706

申请日：2011-07-28

申请人： Wade M. Demmer ,  Karen J. Kleckner ,  Paul A. Belk

发明人： Wade M. Demmer ,  Karen J. Kleckner ,  Paul A. Belk

IPC分类号： A61N1/362

CPC分类号： A61N1/36514 ,  A61N1/36507 ,  A61N1/36592

摘要： Cardiac pacing methods for an implantable single chamber pacing system, establish an offset rate for pacing at a predetermined decrement from either a baseline rate (i.e. dictated by a rate response sensor), or an intrinsic rate. Pacing maintains the offset rate until x of y successive events are paced events, at which time the offset rate is switched to the baseline rate for pacing over a predetermined period of time. Following the period, if an intrinsic event is not immediately detected, within the interval of the offset rate, the rate is switched back to baseline for pacing over an increased period of time. Some methods establish a preference rate, between the offset and baseline rates, wherein an additional criterion, for switching from the offset rate to the baseline rate, is established with respect to the preference rate.

公开(公告)号：US20130150912A1

公开(公告)日：2013-06-13

申请号：US13707204

申请日：2012-12-06

申请人： David L. Perschbacher ,  Arjun D. Sharma ,  Craig Stolen ,  Kira Q. Stolen ,  Milan Seth ,  Paul W. Jones

发明人： David L. Perschbacher ,  Arjun D. Sharma ,  Craig Stolen ,  Kira Q. Stolen ,  Milan Seth ,  Paul W. Jones

IPC分类号： A61N1/365

CPC分类号： A61N1/36592 ,  A61B5/02405 ,  A61B5/1116 ,  A61B5/7275 ,  A61N1/36507 ,  A61N1/36535 ,  A61N1/36585

摘要： A heart rate variability or heart rate variation can be identified using sensed and/or paced heart beats. One or more patient metrics, such as a variability index or a variation index, can correspond to the identified heart rate variability or heart rate variation. The patient metrics can be used to identify a need for a particular therapy, such as a rate-responsive pacing therapy. The patient metrics can be used to identify patients at an elevated risk of death. Methods and systems to identify therapy indications or at-risk patients are provided. In an example, a patient risk profile can be adjusted, such as in response to an identified patient heart rate variability or heart rate variation. In an example, a rate-responsive pacing mode can be used to adjust the patient risk profile.

公开(公告)号：US20130085539A1

公开(公告)日：2013-04-04

申请号：US13686352

申请日：2012-11-27

申请人： Cardiac Pacemakers, Inc.

发明人： Barun Maskara ,  Jiang Ding

IPC分类号： A61N1/368 ,  A61N1/365

CPC分类号： A61N1/3682 ,  A61N1/3627 ,  A61N1/36507 ,  A61N1/368 ,  A61N1/3684

摘要： Systems and methods for pacing the heart using resynchronization pacing delays that achieve improvement of cardiac function are described. An early activation pacing interval is calculated based on an optimal AV delay and an atrial to early ventricular activation interval between an atrial event and early activation of a ventricular depolarization. The early activation pacing interval for the ventricle is calculated by subtracting the measured AVEA from the calculated optimal AV delay. The early activation pacing interval is initiated responsive to sensing early activation of the ventricle and pacing is delivered relative to expiration of the early activation pacing interval.

摘要翻译： 描述了实现心脏功能改善的再同步起搏延迟来起搏心脏的系统和方法。 基于最佳AV延迟和心房事件与心室去极化的早期激活之间的早期心室激活间隔来计算早期激活起搏间隔。 通过从计算的最佳AV延迟中减去测量的AVEA来计算心室的早期激活起搏间隔。 响应于感测心室的早期激活而启动早期激活起搏间隔，并且相对于早期激活起搏间隔的期满而递送起搏。

公开(公告)号：US08369949B2

公开(公告)日：2013-02-05

申请号：US12724021

申请日：2010-03-15

申请人： Jeffrey E. Stahmann ,  Rene H. Wentkowski ,  Andrew P. Kramer ,  James Kalgren

发明人： Jeffrey E. Stahmann ,  Rene H. Wentkowski ,  Andrew P. Kramer ,  James Kalgren

IPC分类号： A61N1/368

CPC分类号： A61N1/36507 ,  A61N1/3627 ,  A61N1/3684

摘要： A system and method for recording sensing and pacing events in a cardiac rhythm management device. The method may be particularly useful in assessment of pacing parameters for ventricular resynchronization therapy.

摘要翻译： 用于在心律管理装置中记录感测和起搏事件的系统和方法。 该方法在评价心室再同步治疗的起搏参数方面特别有用。

公开(公告)号：US20130030489A1

公开(公告)日：2013-01-31

申请号：US13193747

申请日：2011-07-29

申请人： Nathan P. Munsterman ,  Robert A. Betzold

发明人： Nathan P. Munsterman ,  Robert A. Betzold

IPC分类号： A61N1/365

CPC分类号： A61N1/3682 ,  A61B5/0422 ,  A61B5/0452 ,  A61B5/686 ,  A61B5/6869 ,  A61N1/3627 ,  A61N1/36507

摘要： Methods and/or devices for sampling a patient's intrinsic AV conduction time during cardiac therapy that may, e.g., change the AV delays to values based on the AV delays themselves, previously-sampled intrinsic AV conduction times, and/or one or more other parameters directly related to AV delays to provide a time period during which to measure the patient's intrinsic AV conduction time.

摘要翻译： 用于在心脏治疗期间取样患者固有AV传导时间的方法和/或装置，其可以例如基于AV延迟本身将AV延迟改变为值，先前采样的固有AV传导时间和/或一个或多个其它参数 与AV延迟直接相关，以提供测量患者固有AV传导时间的时间段。