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211 条记录 (耗时 0.034 秒)

    Redox polymers
    85.
    发明授权
    Redox polymers 有权
    氧化还原聚合物

    公开(公告)号：US08092662B2

    公开(公告)日：2012-01-10

    申请号：US12371504

    申请日：2009-02-13

    申请人： Fei Mao ,  Adam Heller

    发明人： Fei Mao ,  Adam Heller

    IPC分类号： G01N27/327

    CPC分类号： A61B5/1486 ,  A61B5/14532 ,  A61B5/1477 ,  C07F9/005 ,  C07F15/0026 ,  C07F15/0053 ,  C07F15/025 ,  C07F15/065 ,  C08F8/42 ,  C08F8/44 ,  C09B57/10 ,  C12Q1/004

    摘要： Novel transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators in enzyme based electrochemical sensors. In such instances, transition metal complexes accept electrons from, or transfer electrons to, enzymes at a high rate and also exchange electrons rapidly with the sensor. The transition metal complexes include at least one substituted or unsubstituted biimidazole ligand and may further include a second substituted or unsubstituted biimidazole ligand or a substituted or unsubstituted bipyridine or pyridylimidazole ligand. Transition metal complexes attached to polymeric backbones are also described.

    摘要翻译： 描述了铁，钴，钌，锇和钒的新型过渡金属络合物。 过渡金属络合物可用作酶基电化学传感器中的氧化还原介质。 在这种情况下，过渡金属配合物以高速率接受电子或将电子转移到酶，并且还与传感器快速交换电子。 过渡金属络合物包括至少一个取代或未取代的双咪唑配体，并且还可以包括第二取代或未取代的双咪唑配体或取代或未取代的联吡啶或吡啶基咪唑配体。 还描述了连接到聚合物主链上的过渡金属络合物。

    Aromatic monomer- and conjugated polymer-metal complexes
    86.
    发明授权
    Aromatic monomer- and conjugated polymer-metal complexes 有权
    芳族单体和共轭聚合物 - 金属络合物

    公开(公告)号：US08071769B2

    公开(公告)日：2011-12-06

    申请号：US12718238

    申请日：2010-03-05

    申请人： Wanglin Yu ,  James J. O'Brien

    发明人： Wanglin Yu ,  James J. O'Brien

    IPC分类号： C07F15/00

    CPC分类号： C07F15/008 ,  C07F15/0026 ,  C07F15/004 ,  C09K11/06 ,  C09K2211/1425 ,  C09K2211/185 ,  H01L51/0035 ,  H01L51/0085 ,  H05B33/14 ,  Y10S428/917

    摘要： A halogenated aromatic monomer-metal complex useful for preparing a polymer for electronic devices such as a light-emitting diode (LED) device is described. The aromatic monomer-metal complex is designed to include a linking group that disrupts conjugation, thereby advantageously reducing or preventing electron delocalization between the aromatic monomer fragment and the metal complex fragment. Disruption of conjugation is often desirable to preserve the phosphorescent emission properties of the metal complex in a polymer formed from the aromatic monomer-metal complex. The resultant conjugated electroluminescent polymer has precisely controlled metal complexation and electronic properties that are substantially or completely independent of those of the polymer backbone.

    摘要翻译： 描述了可用于制备诸如发光二极管（LED）装置的电子器件的聚合物的卤化芳族单体 - 金属络合物。 芳族单体 - 金属络合物被设计为包括破坏共轭的连接基团，从而有利地减少或防止芳族单体片段和金属络合物片段之间的电子离域化。 通常需要破坏共轭，以保持由芳族单体 - 金属络合物形成的聚合物中的金属络合物的磷光发射性能。 所得的共轭电致发光聚合物具有精确控制的金属络合和电子性能，其基本上或完全独立于聚合物主链。

    AROMATIC MONOMER- AND CONJUGATED POLYMER-METAL COMPLEXES
    87.
    发明申请
    AROMATIC MONOMER- AND CONJUGATED POLYMER-METAL COMPLEXES 审中-公开
    芳族单体和共轭聚合物金属复合物

    公开(公告)号：US20110172426A1

    公开(公告)日：2011-07-14

    申请号：US13053776

    申请日：2011-03-22

    申请人： Wanglin YU ,  James J. O'Brien

    发明人： Wanglin YU ,  James J. O'Brien

    IPC分类号： C07F15/00

    CPC分类号： C07F15/008 ,  C07F15/0026 ,  C07F15/004 ,  C09K11/06 ,  C09K2211/1425 ,  C09K2211/185 ,  H01L51/0035 ,  H01L51/0085 ,  H05B33/14 ,  Y10S428/917

    摘要： A halogenated aromatic monomer-metal complex useful for preparing a polymer for electronic devices such as a light-emitting diode (LED) device is described. The aromatic monomer-metal complex is designed to include a linking group that disrupts conjugation, thereby advantageously reducing or preventing electron delocalization between the aromatic monomer fragment and the metal complex fragment. Disruption of conjugation is often desirable to preserve the phosphorescent emission properties of the metal complex in a polymer formed from the aromatic monomer-metal complex. The resultant conjugated electroluminescent polymer has precisely controlled metal complexation and electronic properties that are substantially or completely independent of those of the polymer backbone.

    摘要翻译： 描述了可用于制备诸如发光二极管（LED）装置的电子器件的聚合物的卤化芳族单体 - 金属络合物。 芳族单体 - 金属络合物被设计为包括破坏共轭的连接基团，从而有利地减少或防止芳族单体片段和金属络合物片段之间的电子离域化。 通常需要破坏共轭，以保持由芳族单体 - 金属络合物形成的聚合物中的金属络合物的磷光发射性能。 所得的共轭电致发光聚合物具有精确控制的金属络合和电子性能，其基本上或完全独立于聚合物主链。

    DNA threading intercalators
    88.
    发明授权
    DNA threading intercalators 失效
    DNA穿线嵌入剂

    公开(公告)号：US07902362B2

    公开(公告)日：2011-03-08

    申请号：US12317359

    申请日：2008-12-22

    申请人： Zhiqiang Gao ,  Fang Xie

    发明人： Zhiqiang Gao ,  Fang Xie

    IPC分类号： C07F15/00 ,  C12Q1/68

    CPC分类号： C07F15/0026

    摘要： The invention is directed to a compound having the general formula (1): wherein each of La and Lb is an independently selected from a linking moiety comprising 0 to 10 main chain atoms, optionally substituted; each of Za and Zb is an independently selected complexing moiety comprising at least one nitrogen atom; either both or one of Za and/or Zb is coordinatively bonded to a respective transition metal complex Ma Va and Mb Vb through said nitrogen atom, wherein each of Ma and Mb is an independently selected transition metal, and each of Va and Vb is an independently selected valence group.

    摘要翻译： 本发明涉及具有通式（1）的化合物：其中La和Lb各自独立地选自包含0至10个主链原子的连接部分，任选取代的; Za和Zb中的每一个是包含至少一个氮原子的独立选择的络合部分; Za和/或Zb中的任一个或Zb通过所述氮原子与相应的过渡金属络合物Ma Va和Mb Vb配位键合，其中Ma和Mb各自为独立选择的过渡金属，Va和Vb中的每一个为 独立选择的价电子基团。

    Mediator-modified redox biomolecules for use in electrochemical determination of analyte
    89.
    发明授权
    Mediator-modified redox biomolecules for use in electrochemical determination of analyte 有权
    用于电化学测定分析物的中间体修饰的氧化还原生物分子

    公开(公告)号：US07807835B2

    公开(公告)日：2010-10-05

    申请号：US12413214

    申请日：2009-03-27

    申请人： Hong Xie ,  Zhiqiang Gao

    发明人： Hong Xie ,  Zhiqiang Gao

    IPC分类号： C07F15/00 ,  C12Q1/26

    CPC分类号： C07F15/0026

    摘要： Compositions and methods for electrochemical detection of an analyte comprising a transition metal compound wherein M is a metallic element that can form a coordinate bond to nitrogen; R and R′ are coordinated to M at their nitrogen atoms; L is a linking ligand; Z is chlorine or bromine; m can be from 1 to 6 and X is an anion, or combination of anions, that balances the charge m. Also provided are electrochemical tags and methods of detection.

    摘要翻译： 用于电化学检测包含过渡金属化合物的分析物的组合物和方法，其中M是能够形成与氮的配位键的金属元素; R和R'在氮原子上与M配位; L是连接配体; Z是氯或溴; m可以是1至6，X是阴离子或阴离子的组合，其平衡电荷m。 还提供了电化学标签和检测方法。

    Method and device for electrochemical immunoassay of multiple analytes
    90.
    再颁专利
    Method and device for electrochemical immunoassay of multiple analytes 有权
    多种分析物的电化学免疫测定方法和装置

    公开(公告)号：USRE40198E1

    公开(公告)日：2008-04-01

    申请号：US10671436

    申请日：2003-09-25

    申请人： Harvey B. Buck, Jr. ,  Zhi David Deng ,  Eric R. Diebold

    发明人： Harvey B. Buck, Jr. ,  Zhi David Deng ,  Eric R. Diebold

    IPC分类号： G01N27/327

    CPC分类号： C07F15/0026 ,  C07K5/101 ,  C07K7/02 ,  C07K7/06 ,  C07K9/001 ,  C07K14/805 ,  G01N27/3277 ,  G01N33/532 ,  G01N33/536 ,  G01N33/58 ,  G01N33/723 ,  G01N2333/805 ,  G01N2458/30 ,  Y10S436/805 ,  Y10S436/806 ,  Y10T436/105831

    摘要： A method and device for detection and quantification of biologically significant analytes in a liquid sample is described. The method includes contacting a volume of a liquid sample with predetermined amounts of at least a first and second redox reversible species having redox potentials differing by at least 50 millivolts. At least one of the redox reversible species comprises a liquid sample diffusible conjugate of a ligand analog of an analyte in the liquid sample and a redox reversible label. A predetermined amount of at least one specific binding partner for each analyte to be measured is combined with the sample and current flow is measured at first and second anodic and cathodic potentials and correlated with current flows for known concentrations of the respective diffusible redox reversible species. Diagnostic devices and kits, including such devices and the specified specific binding partner(s) and redox reversible species are also described.

    摘要翻译： 描述了用于在液体样品中检测和定量生物学显着性分析物的方法和装置。 该方法包括使体积的液体样品与预定量的至少50毫伏的氧化还原电位的至少第一和第二氧化还原可逆物质接触。 至少一种氧化还原可逆物质包括液体样品中分析物的配体类似物和氧化还原可逆标记的液体样品可扩散共轭物。 将待测量的每种待测量分析物的至少一个特定结合配偶体的预定量与样品组合，并且在第一和第二阳极和阴极电位处测量电流，并且与已知浓度的各个可扩散的氧化还原可逆物质的电流相关。 还描述了诊断装置和试剂盒，包括这些装置和指定的特异性结合配偶体和氧化还原可逆物质。