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    Method for quantification of biological material in a sample
    2.
    发明授权
    Method for quantification of biological material in a sample 有权
    用于定量样品中生物材料的方法

    公开(公告)号：US07122338B2

    公开(公告)日：2006-10-17

    申请号：US10349196

    申请日：2003-01-21

    Applicant: Andrew J. Crouteau ,  Mark W. Pierson ,  David E. Townsend ,  Ali Naqui

    Inventor： Andrew J. Crouteau ,  Mark W. Pierson ,  David E. Townsend ,  Ali Naqui

    IPC: C12Q1/24

    CPC classification number: B01L3/5088 ,  B01L3/5085 ,  B01L3/50853 ,  B01L2300/0803 ,  C12M23/12 ,  C12M23/20 ,  C12M23/22 ,  C12M23/38 ,  C12M25/14 ,  C12M35/08 ,  C12M37/00 ,  C12M41/36 ,  C12Q1/24

    Abstract: Methods for the detection and/or quantification of a biological material in a sample. The method includes the steps of liquefying the sample (if necessary) and pouring the liquefied sample into the incubation vessel. The incubation vessel has a generally flat horizontal surface and the surface is divided into at least one incubation site. Each incubation site is adapted to hold an aliquot of liquid and is sized and shaped, and formed of a suitable material, to hold the aliquot within the well by surface tension. Any excess liquid from the liquefied sample is poured from the surface of the incubation vessel. The method then involves incubating that incubation vessel until the presence or absence of the biological material is determined. The presence of air bubbles can be dramatically reduced by the presence of a surface acting agent in the liquid sample deposited on the device surface. Such an agent can be added to the sterile diluent used to prepare the test reagent, can be separately added to the test reagent after it is prepared, or can be added to the test sample directly while it is being prepared for testing.

    Abstract translation: 用于检测和/或定量样品中生物材料的方法。 该方法包括如下步骤：将样品液化（如有必要）并将液化的样品倒入培养容器中。 培养容器具有大致平坦的水平表面，并且将表面分成至少一个孵育位点。 每个孵化位点适于保持液体的等分试样，并且其尺寸和形状由合适的材料形成，以通过表面张力将等分试样保持在孔内。 从培养容器的表面倒出来自液化样品的任何多余的液体。 然后，该方法包括孵育该培养容器，直到确定生物材料的存在或不存在。 通过在沉积在器件表面上的液体样品中存在表面作用剂，可以显着降低气泡的存在。 可以将这样的试剂加入用于制备测试试剂的无菌稀释剂中，可以在制备试剂后分别添加到试验试剂中，或者可以在制备试剂时直接加入试验样品中。

    Method and composition for detecting bacterial contamination in food products
    5.
    发明申请
    Method and composition for detecting bacterial contamination in food products 审中-公开

    公开(公告)号：US20020031796A1

    公开(公告)日：2002-03-14

    申请号：US09923695

    申请日：2001-08-06

    Applicant: Biocontrol Systems, Inc.

    Inventor： David E. Townsend ,  Chun-Ming Chen

    IPC: C12Q001/04

    CPC classification number: C12Q1/045 ,  C12Q1/04

    Abstract: This invention relates to a method for detecting the existence or measuring the concentration of total viable bacteria in a test sample from a food product. A medium is provided which contains three or more different enzyme substrates each having a nutrient moiety and a detectable moiety linked together. When a substrate is hydrolysed by a bacterial enzyme to create a separate detectable moiety, it causes or produces a detectable signal. These substrates produce detectable signals when any one of a phosphatase enzyme, a glycosidase enzyme or a peptidase enzyme is present in the medium.

    Magnetic enrichment method, a reactor unit for micro particles and a magnet unit
    6.
    发明授权
    Magnetic enrichment method, a reactor unit for micro particles and a magnet unit 有权
    磁力富集法，微粒子反应器单元和磁体单元

    公开(公告)号：US08247204B2

    公开(公告)日：2012-08-21

    申请号：US10576298

    申请日：2004-10-20

    Applicant: Matti Korpela ,  Kenneth Rundt

    Inventor： Matti Korpela ,  Kenneth Rundt

    IPC: C12N13/00

    CPC classification number: G01N1/28 ,  B03C1/286 ,  B03C2201/18 ,  B03C2201/26 ,  G01N33/54326 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/25375 ,  Y10T436/2575

    Abstract: Magnetic enrichment method, wherein the desired biological component is collected from a solution, which component is thereafter enriched in a liquid in such a manner that by means of the micro particles attached to the magnet or attached by means of at least one magnet at least one biological component is collected in a closed reactor vessel. Thereafter at least one biological component is enriched in such a manner that the desired component is released to the solution. The reactor unit is a closed vessel, wherein the prevailing conditions are controllable. The shape and the location of the magnet unit in the reactor unit are adjusted in a preferable manner to collect the desired biological component.

    Abstract translation: 磁性富集方法，其中从溶液中收集所需的生物成分，该组分此后富集液体，使得通过附着在磁体上的微粒子或借助于至少一个磁体至少一个 将生物成分收集在封闭的反应器容器中。 此后，至少一种生物成分以使所需成分释放到溶液中的方式富集。 反应器单元是密闭容器，其中主要条件是可控的。 以优选方式调节反应器单元中的磁体单元的形状和位置，以收集所需的生物组分。

    Sample collection and testing system
    8.
    发明申请
    Sample collection and testing system 有权
    样本收集和检测系统

    公开(公告)号：US20040220748A1

    公开(公告)日：2004-11-04

    申请号：US10861299

    申请日：2004-06-04

    Applicant: Biocontrol Systems, Inc.

    Inventor： Philip T. Feldsine ,  Tim A. Kelly ,  Jim Christensen ,  Joseph B. Di Carlo ,  Mark Andersen ,  Anita Kressner

    IPC: C12Q001/66 ,  G06F019/00 ,  G01N033/48 ,  G01N033/50

    CPC classification number: G01N21/76

    Abstract: Methods and apparatus for evaluating the quality of a sample of a product, an ingredient, an environment or a process by measuring multiple parameters thereof, including light emitted from a reacting sample containing ATP, ADP, alkaline phosphatase or other parameters such as pH, temperature, conductivity, oxidation reduction potential, dissolved gases, specific ions, and microbiological count. The apparatus comprises an integrated sample testing device used to collect a sample, mix reagents, react the sample, and collect it in a measurement chamber. The apparatus also comprises an instrument having a photon detection assembly for use with the sample testing device. The instrument can also comprise one or more sensing probes and a communication port to facilitate data collection, transfer and analysis. The method further comprises a mechanism for storing data, evaluating data, graphing data, and determining conformance to established criteria.

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