公开(公告)号：US20240287565A1

公开(公告)日：2024-08-29

申请号：US18546949

申请日：2022-02-22

申请人： Chr. Hansen A/S

发明人： Vojislav VOJINOVIC ,  Kim Ib SOERENSEN ,  Laurent GUINOT

IPC分类号： C12P19/12 ,  A23C9/123 ,  C12N1/20 ,  C12N9/12 ,  C12R1/46

CPC分类号： C12P19/12 ,  A23C9/1238 ,  C12N1/20 ,  C12N9/1205 ,  C12R2001/46 ,  C12Y207/01002 ,  C12Y207/01006

摘要： The invention relates to a method of obtaining a composition comprising allolactose by a applying one or more glucose-deficient lactic acid bacteria strains. The invention also relates to the use of said strains for the preparation of a food product comprising allolactose and to the use of said strains for increasing the content of allolactose in a food product. The invention also relates to a food product comprising allolactose and one or more glucose-deficient lactic acid bacteria strains.

公开(公告)号：US20240237663A1

公开(公告)日：2024-07-18

申请号：US18559720

申请日：2022-05-05

申请人： Chr. Hansen A/S

发明人： Victoria Prebner ,  Vojislav Vojinovic ,  Maria Elina Sundberg

IPC分类号： A23C9/12 ,  A23C9/123 ,  C12N1/20 ,  C12N9/24 ,  C12R1/225 ,  C12R1/46

CPC分类号： A23C9/1206 ,  A23C9/1238 ,  C12N1/205 ,  C12N9/2402 ,  C12Y302/01108 ,  A23V2400/123 ,  A23V2400/249 ,  C12R2001/225 ,  C12R2001/46

摘要： The present invention is in the field of dairy technology. It relates to a method for producing a fermented milk product comprising the steps: (a) Providing a starter culture comprising one or more lactic acid bacteria strains selected from a group consisting of: DSM 22935, DSM 22585, DSM 22586, DSM28910 and DSM33677; (b) Adding the starter culture to a milk base to ferment said milk base until a target pH is reached; and (c) Adding a lactase to the milk base; wherein the fermented milk product has improved texture and/or reduced post-acidification as compared to a fermented milk product produced without addition of the lactase of step c) or the starter culture of step a).

公开(公告)号：US20240229093A1

公开(公告)日：2024-07-11

申请号：US18562047

申请日：2021-05-20

申请人： Chr. Hansen A/S

发明人： Katja Parschat ,  Stefan Jennewein

IPC分类号： C12P19/26 ,  C12N1/16 ,  C12N1/20 ,  C12N9/10 ,  C12R1/07 ,  C12R1/185 ,  C12R1/78 ,  C12R1/84 ,  C12R1/85

CPC分类号： C12P19/26 ,  C12N1/16 ,  C12N1/20 ,  C12N9/1051 ,  C12N2500/34 ,  C12R2001/07 ,  C12R2001/185 ,  C12R2001/78 ,  C12R2001/84 ,  C12R2001/85 ,  C12Y204/0109

摘要： Disclosed is a process for the production of a desired oligosaccharide, the process comprises providing a genetically engineered microbial cell which possesses a saccharide importer for the uptake of an intermediate oligosaccharide, and an enzyme being able to convert the intermediated oligosaccharide by transferring a monosaccharide moiety from a donor substrate to the intermediate oligosaccharide; cultivating the genetically engineered microbial cell in the presence of an intermediate oligosaccharide to generate the desired oligosaccharide; and retrieving the desired oligosaccharide.

公开(公告)号：US20240132832A1

公开(公告)日：2024-04-25

申请号：US18254658

申请日：2021-11-29

申请人： Chr. Hansen A/S

发明人： Zuzana Mladenovska ,  Surender Kumar Dhayal ,  Kim Nielsen

IPC分类号： C12N1/04 ,  C12N1/20

CPC分类号： C12N1/04 ,  C12N1/20

摘要： The present invention relates to the field of frozen or dry compositions for prokaryotes, in particular fermentative bacteria such as lactic acid bacteria, a method for preparing frozen or dry prokaryotic compositions and compositions which may be prepared by said method. The cells in a cell concentrate are activated by allowing them to ferment a carbohydrate, before freezing and/or drying to provide a product. The hydrophobicity of the cell surface increases during activation, and this has been found to increase the storage stability of the product.

公开(公告)号：US20230149484A1

公开(公告)日：2023-05-18

申请号：US18147948

申请日：2022-12-29

申请人： Chr. Hansen A/S

发明人： Pravas Ranjan Misra

IPC分类号： A61K35/747 ,  A61K9/00 ,  A61K31/702

CPC分类号： A61K35/747 ,  A61K9/0029 ,  A61K9/0053 ,  A61K31/702

摘要： The present invention provides a pharmaceutical composition including a probiotic and a prebiotic for treatment of stunting in children. More particularly, the pharmaceutical composition includes at least one Lactobacillus specie(s) as a probiotic and at least one oligosaccharide as a prebiotic. The present invention further provides a method of treatment of stunting including administering an effective amount of a pharmaceutical composition including a probiotic and a prebiotic to children in need thereof.

公开(公告)号：US11540527B2

公开(公告)日：2023-01-03

申请号：US16061638

申请日：2016-12-16

申请人： Chr. Hansen A/S

发明人： Gaelle Lettier Buchhorn ,  Kim Ib Soerensen ,  Mette Pia Junge

IPC分类号： A23C9/123

摘要： The present invention relates to a Streptococcus thermophilus strain, wherein the strain is galactose-fermenting, wherein the strain carries a mutation in the DNA sequence of the glcK gene encoding a glucokinase protein, wherein the mutation inactivates the glucokinase protein or has a negative effect on expression of the gene, and wherein the strain carries a mutation in the promoter region of the GalK gene encoding a galactokinase protein.

公开(公告)号：US20220256872A1

公开(公告)日：2022-08-18

申请号：US17613905

申请日：2020-05-26

申请人： Chr. Hansen A/S

发明人： Mirjana CURIC-BAWDEN ,  Matt NICHOLSON

IPC分类号： A23C9/123

摘要： The present invention relates to compositions and methods for producing fermented milk products with increased amount of probiotic bacteria. In particular, the invention relates to a process for producing a fermented milk which comprises adding to a milk base (i) a starter culture comprising at least one lactose-deficient Streptococcus thermophilus strain, which is capable of metabolizing a non-lactose carbohydrate, and at least one lactose-deficient Lactobacillus strain, which is capable of metabolizing a non-lactose carbohydrate, (ii) one or more non-lactose carbohydrate capable of being metabolized by the lactic acid bacteria, in an amount measured so as to become depleted when the pH of the fermented milk product is between 4.9 and 5.5 and (iii) a probiotic strain selected from a Lactobacillus strain and a Bifidobacterium strain. In addition, the present invention relates to compositions and to fermented milk food or feed products produced by the process of the invention.

公开(公告)号：US20220154162A1

公开(公告)日：2022-05-19

申请号：US17571413

申请日：2022-01-07

申请人： Chr. Hansen A/S

发明人： Johannes Maarten VAN DEN BRINK ,  Jesper Langholm JENSEN ,  Jonas JACOBSEN ,  Martin LUND ,  Iben JEPPESEN ,  Christian JAECKEL

IPC分类号： C12N9/64 ,  A23C19/04

摘要： Variants of chymosin with improved milk-clotting properties are disclosed.

公开(公告)号：US11246320B2

公开(公告)日：2022-02-15

申请号：US16479144

申请日：2018-01-08

申请人： Chr. Hansen A/S

发明人： Surender Kumar Dhayal ,  Martin Lund ,  Johannes Maarten Van Den Brink

IPC分类号： A23C21/02 ,  A23L33/18 ,  A23L33/19

摘要： A method for making a new food, feed or pharmaceutical product comprising addition of a composition comprising cross-linked, via intermolecular covalent isopeptide bonds, casein glycomacropeptide (CGMP) oligomers (CGMP oligomers) to the product.

公开(公告)号：US20220007666A1

公开(公告)日：2022-01-13

申请号：US17291845

申请日：2019-11-08

申请人： Chr. Hansen A/S

发明人： Sebastien ROUSTEL ,  Michael Mitsuo SAITO

IPC分类号： A23C19/032 ,  A23C19/068

摘要： The present invention is in the field of dairy technology. It relates to methods of inhibiting the growth of unwanted microorganisms, such as Gram-negative bacteria, yeasts or molds in dairy products by using phospholipase to treat the milk base. The invention also provides dairy products produced therefrom.