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公开(公告)号：US12051584B2
公开(公告)日：2024-07-30
申请号：US16836708
申请日：2020-03-31
CPC分类号： H01J49/067 , H01J49/0495 , H01J49/10 , H01J49/4225
摘要： Certain embodiments of ion interfaces are described that can provide higher sensitivities improved ion transmission and multiple operating modes. In some configurations, the ion interface may comprise a first element and a second element each of which can receive a non-zero voltage. In one configuration, the first element can be a hyperskimmer cone and the second element can be a cylindrical lens. Systems and methods using the interface are also described.
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2.发明公开公开(公告)号：US20240055248A1
公开(公告)日：2024-02-15
申请号：US18384075
申请日：2023-10-26
发明人： Hamid Badiei , Brian Chan
CPC分类号： H01J49/068 , H01J49/105 , H01J49/04 , H01J49/067
摘要： Certain configurations of a sampler cone and its use with a metal gasket to seal the sampler cone to a mass spectrometer interface are described. The sampler cone, interface or both may comprise one or more surface features. Coupling of the sampler cone to the interface can compress or crush the metal gasket to provide a seal between the sampler cone and the interface. For example, a crushing force provided by surface features of the sampler cone and interface can crush the gasket and provide a substantially fluid tight seal between the sampler cone and the interface.
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3.发明公开公开(公告)号：US20240347332A1
公开(公告)日：2024-10-17
申请号：US18630960
申请日：2024-04-09
CPC分类号： H01J49/022 , H01J49/061 , H01J49/067 , H01J49/40
摘要： Certain configurations of mass spectrometer components are described herein that comprise one or more mass spectrometer programmable elements. In some instances, the mass spectrometer programmable element can be configured as an electrode that can function independently of any underlying substrate or component. Ion guides, lenses, ion switches, mass analyzers and other components of a mass spectrometer are described which comprise one or more mass spectrometer programmable elements.
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公开(公告)号：US11917744B2
公开(公告)日：2024-02-27
申请号：US17383060
申请日：2021-07-22
CPC分类号： H05H1/28 , H01J49/0468 , H01J49/105 , H05H1/4652 , G01J3/443
摘要： A system for cooling an inductively coupled plasma (ICP) instrument includes: the ICP instrument; a pump in fluid communication with the instrument via a first conduit; and a micro-channel heat exchanger in fluid communication with the instrument via a second conduit, and in fluid communication with the pump via a third conduit. The pump is configured to generate a pump outlet pressure of coolant that exceeds a back pressure of the instrument such that a pressure of the coolant traveling through the second conduit and into the heat exchanger is less than or equal to 5 pounds per square inch (psi) above atmospheric pressure, as measured at an inlet to the heat exchanger.
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公开(公告)号：US11908675B2
公开(公告)日：2024-02-20
申请号：US17672167
申请日：2022-02-15
CPC分类号： H01J49/062 , H01J49/063 , H01J49/42
摘要： An ion guide includes a plurality of curved electrodes arranged along a curved central axis. The plurality of electrodes define a curved ion guide region, with the curved ion guide region beginning at an ion entrance and ending at an ion exit. The ion guide includes an ion deflecting device configured to apply a radial DC electric field across the ion guide region and along the curved central axis. The ion guide region has a radius of curvature that varies along the curved central axis, and the radius of curvature is at a maximum at the ion entrance and decreases along the curved central axis toward the ion exit.
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公开(公告)号：US20240027409A1
公开(公告)日：2024-01-25
申请号：US17871393
申请日：2022-07-22
发明人： Charles Jolliffe
IPC分类号： G01N30/72 , G01N30/84 , G01N27/623
CPC分类号： G01N30/7246 , G01N30/84 , G01N27/623 , G01N2030/847
摘要： A nebulizer includes a gas transport conduit having a gas inlet for receiving a nebulizer gas and an outlet, the gas transport conduit defining a longitudinal axis along flow direction of the nebulizer gas; and an analyte supply conduit extending into the gas transport conduit along the longitudinal axis, the analyte supply conduit having at least one side aperture configured to emit analyte from the analyte supply conduit into the gas transport conduit in a direction off-axis from the longitudinal axis of the gas transport conduit.
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公开(公告)号：US20240074024A1
公开(公告)日：2024-02-29
申请号：US17822843
申请日：2022-08-29
发明人： Brian Chan , Joshua O. Oseh
CPC分类号： H05H1/01 , H01J49/105 , H05H1/30
摘要： An inductively coupled plasma (ICP) torch includes: an injector defining an injector flow passage to receive a flow of a sample fluid; a plurality of tubes disposed about the injector and configured to receive and direct a flow of one or more torch gases; an induction device disposed about the plurality of tubes, the induction device configured to receive a radio-frequency electric current to inductively energize at least one of the one or more torch gases to produce a plasma proximate a distal end of the ICP torch; and a plasma steering system including a plurality of nozzles adjacent a distal end of the injector flow passage and configured to receive and direct a flow of steering fluid to impinge and redirect the flow of sample fluid and to thereby redirect an ionized sample resulting from the interaction of the sample fluid with the plasma.
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公开(公告)号：US20230260771A1
公开(公告)日：2023-08-17
申请号：US17672167
申请日：2022-02-15
IPC分类号： H01J49/06
CPC分类号： H01J49/062 , H01J49/42
摘要： An ion guide includes a plurality of curved electrodes arranged along a curved central axis. The plurality of electrodes define a curved ion guide region, with the curved ion guide region beginning at an ion entrance and ending at an ion exit. The ion guide includes an ion deflecting device configured to apply a radial DC electric field across the ion guide region and along the curved central axis. The ion guide region has a radius of curvature that varies along the curved central axis, and the radius of curvature is at a maximum at the ion entrance and decreases along the curved central axis toward the ion exit.
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公开(公告)号：US11705319B2
公开(公告)日：2023-07-18
申请号：US17340041
申请日：2021-06-06
CPC分类号： H01J49/123 , H01J37/32009 , H01J49/107
摘要： Certain configurations of plasma discharge chambers and plasma ionization sources comprising a plasma discharge chamber are described. In some examples, the discharge chamber comprises a conductive area and is configured to sustain a plasma discharge within the discharge chamber. In other examples, the discharge chamber comprises at least one inlet configured to receive a plasma gas and at least one outlet configured to provide ionized analyte from the discharge chamber. Systems and methods using the discharge chambers are also described.
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