公开(公告)号：US08071314B2

公开(公告)日：2011-12-06

申请号：US10321704

申请日：2002-12-16

申请人： Carla J. Shatz ,  Joshua Syken

发明人： Carla J. Shatz ,  Joshua Syken

IPC分类号： G01N33/567 ,  G01N33/48

CPC分类号： C07K14/705 ,  A61K48/00 ,  G01N33/56977 ,  G01N33/6896

摘要： Class I major histocompatibility complex, is required in the activity-dependent refinement and plasticity of connections in the developing and adult central nervous system, demonstrating that molecules can perform critical roles in both systems. Similarities in the cellular signaling mechanisms of the immune and nervous systems provide for development of therapeutic and diagnostic agents in abnormal neuronal cellular function.

摘要翻译： I类主要组织相容性复合物在发育中和成人中枢神经系统的连接活动依赖性细化和可塑性中是必需的，表明分子可以在两个系统中起关键作用。 免疫和神经系统的细胞信号机制中的相似性提供了异常神经元细胞功能中的治疗和诊断剂的开发。

公开(公告)号：US08067477B2

公开(公告)日：2011-11-29

申请号：US12864141

申请日：2009-01-21

申请人： Yasunobu Hirota ,  Nobuyoshi Shirai

发明人： Yasunobu Hirota ,  Nobuyoshi Shirai

IPC分类号： C08L67/00

CPC分类号： C08L67/00 ,  C08G63/20 ,  C08G63/60 ,  G03G9/081 ,  G03G9/08755 ,  G03G9/08795 ,  G03G9/08797 ,  G03G9/0904 ,  C08L2666/18

摘要： An object of the present invention is to provide the resin composition for electro-photographic toner, which the electro-photographic toner to be obtained by it is superior to low temperature fixing properties and a hot offset resistance, and the electro-photographic toner thereof. To be achieved this purpose, multi-branched state polyester structure having a structure representing the following structural formula (1) as a repeating unit, is made into a main skeleton (In the formula, R expresses an aliphatic hydrocarbon group, and n shows the number of repeating units of a branched structure and is an average of 1-5.) *a is a node of the carbon atom of a carbonyl group, *b is a node of an oxygen atom, and *b is bonded to *a in the other repeating unit of the structural formula (1)). In addition, polyester resin (A) having a ratio of 25 to 95% of the weight for alkyl group of the number of carbon atoms 20-80 or alkenyl group of the number of carbon atoms 20-80 to the molecular terminal and aliphatic series crystalline polyester resin (B) is contained. The electro-photographic toner containing the resin composition for electro-photographic toner and this composition is provided.

摘要翻译： 本发明的目的是提供一种电子照相调色剂用树脂组合物及其电子照相调色剂，其中所得到的电照相调色剂优于低温定影性和耐热偏移性。 为了实现这一目的，将具有表示以下结构式（1）的结构作为重复单元的多支链状聚酯结构制成主骨架（式中，R表示脂族烃基，n表示 数量的支链结构的重复单元，平均为1-5。）* a是羰基的碳原子的结点，* b是氧原子的结点，* b键合到* a 在结构式（1）的另一重复单元中）。 另外，分子末端的碳原子数为20〜80的烷基的重量比为25〜95％，碳原子数为20〜80的烯基与脂肪族系的聚酯树脂（A） 含有结晶性聚酯树脂（B）。 提供了含有电子照相调色剂用树脂组合物和该组合物的电子照相调色剂。

公开(公告)号：US08066367B2

公开(公告)日：2011-11-29

申请号：US12226496

申请日：2007-04-16

申请人： Yoshinori Nakajima ,  Kaoru Higuchi ,  Toshihiro Tamura

发明人： Yoshinori Nakajima ,  Kaoru Higuchi ,  Toshihiro Tamura

IPC分类号： B41J2/01

CPC分类号： H01L21/6715 ,  B41J3/28

摘要： A droplet applying apparatus includes a base having a mounting surface on which a substrate is to be mounted, an arm part which is fitted to the base so as to be movable relative to the base in an arrow A direction, and a plurality of droplet ejecting sections which are fitted to the arm part so as to be movable in an arrow B direction and which eject droplets to the substrate mounted on the mounting surface. The droplet ejecting sections are fitted on a fitting surface of a first beam member of the arm part as well as on a fitting surface of a second beam member of the arm part.

摘要翻译： 液滴施加装置包括具有安装表面的底座，其上安装有基板;臂部，其安装在基座上，以能够相对于基座沿箭头A方向移动;以及多个液滴喷射 这些部分装配到臂部分上，以便能够沿箭头B方向移动并将液滴喷射到安装在安装表面上的基板上。 液滴喷射部分安装在臂部分的第一梁部件的装配表面上以及臂部件的第二梁部件的装配表面上。

公开(公告)号：US08058280B2

公开(公告)日：2011-11-15

申请号：US11848939

申请日：2007-08-31

申请人： Nobuo Cho ,  Takashi Imada ,  Takenori Hitaka ,  Kazuhiro Miwa ,  Masami Kusaka ,  Nobuhiro Suzuki

发明人： Nobuo Cho ,  Takashi Imada ,  Takenori Hitaka ,  Kazuhiro Miwa ,  Masami Kusaka ,  Nobuhiro Suzuki

IPC分类号： C07D495/04 ,  A61K31/519 ,  A61P5/06

CPC分类号： C07D495/04 ,  A61K31/519

摘要： The present invention provides a compound represented by the formula: wherein R1 is a C1-4 alkyl; R2 is (1) a 5- to 7-membered nitrogen-containing heterocyclic group which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a hydroxy group, (3′) a C1-4 alkyl and (4′) a C1-4 alkoxy, (2) a phenyl which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a C1-4 alkoxy-C1-4 alkyl, (3′) a mono-C1-4 alkyl-carbamoyl-C1-4 alkyl, (4′) a C1-4 alkoxy and (5′) a mono-C1-4 alkylcarbamoyl-C1-4 alkoxy, or the like; R3 is a C1-4 alkyl; R4 is a C1-4 alkoxy, or the like; n is an integer of 1 to 4; or a salt thereof, as a thienopyrimidine compound having gonadotropin-releasing hormone antagonistic activity.

摘要翻译： 本发明提供由下式表示的化合物：其中R1是C1-4烷基; R2是（1）可以具有选自（1'）卤素，（2'）羟基，（3'），C 1〜C 6的取代基的5〜7元含氮杂环基， 4烷基和（4'）C 1-4烷氧基，（2）可具有选自（1'）卤素，（2'）C 1-4烷氧基-C 1-4烷基的取代基的苯基 ，（3'）单-C 1-4烷基 - 氨基甲酰基-C 1-4烷基，（4'）C 1-4烷氧基和（5'）单-C 1-4烷基氨基甲酰基-C 1-4烷氧基等 ; R3是C1-4烷基; R4是C1-4烷氧基等; n为1〜4的整数， 或其盐作为具有促性腺激素释放激素拮抗活性的噻吩并嘧啶化合物。

公开(公告)号：US08058061B2

公开(公告)日：2011-11-15

申请号：US12433412

申请日：2009-04-30

申请人： Michel Sadelain ,  Stefano Rivella ,  Chad May ,  Joseph Bertino

发明人： Michel Sadelain ,  Stefano Rivella ,  Chad May ,  Joseph Bertino

IPC分类号： C12N5/00 ,  C12N15/00 ,  C12N15/67 ,  C12N15/11

CPC分类号： C12N15/86 ,  A61K48/00 ,  A61K48/0066 ,  A61K2035/124 ,  C07K14/805 ,  C12N2510/00 ,  C12N2740/15043

摘要： Recombinant lentiviral vectors having a region encoding a functional β-globin gene; and large portions of the β-globin locus control regions which include DNase I hypersensitive sites HS2, HS3 and HS4 provides expression of β-globin when introduced into a mammal, for example a human, in vivo. Optionally, the vector further includes a region encoding a dihydrofolate reductase. The vector may be used in treatment of hemoglobinopathies, including β-thalessemia and sickle-cell disease. For example, hematopoietic progenitor or stem cells may be transformed ex vivo and then restored to the patient. Selection processes may be used to increase the percentage of transformed cells in the returned population. For example, a selection marker which makes transformed cells more drug resistant than untransformed cells allows selection by treatment of the cells with the corresponding drug.

摘要翻译： 具有编码功能性和珠蛋白基因的区域的重组慢病毒载体; 并且包括DNase I超敏感位点HS2，HS3和HS4的大部分的 - 珠蛋白基因座控制区在体内被引入到哺乳动物例如人中时提供了β-珠蛋白的表达。 任选地，载体还包括编码二氢叶酸还原酶的区域。 该载体可用于治疗血红蛋白病，包括疟原虫和镰状细胞病。 例如，造血祖细胞或干细胞可以离体转化，然后恢复到患者体内。 选择过程可用于增加返回群体中转化细胞的百分比。 例如，使转化细胞比未转化细胞更耐药的选择标记允许通过用相应的药物处理细胞进行选择。

公开(公告)号：US08055092B2

公开(公告)日：2011-11-08

申请号：US12154640

申请日：2008-05-23

申请人： Bong-Su Kang

发明人： Bong-Su Kang

IPC分类号： G06K9/40

CPC分类号： G06T5/008 ,  G06T5/20 ,  G06T2207/20028

摘要： An image processing apparatus is provided, including a brightness change level classifying unit, a dynamic weight calculating unit, and a brightness correcting unit. The brightness change level classifying unit compares a brightness change average value representing brightness changes from a pixel of interest to neighboring pixels around the pixel of interest with an upper threshold value and a lower threshold value and classifies the brightness change level of the pixel of interest into three types of levels according to the result of the comparison. An upper threshold value and a lower threshold value are predetermined based on the brightness of the pixel of interest. The dynamic weight calculating unit calculates different dynamic weights according to the brightness change level of the pixel of interest. The brightness correcting unit corrects the brightness of the pixel of interest, based on the dynamic weights. Accordingly, noise generated on a plane part of an image is minimized and a contour of the image is appropriately emphasized, consequently improving the definition of images.

摘要翻译： 提供一种图像处理装置，包括亮度变化级分类单元，动态权重计算单元和亮度校正单元。 亮度变化级别分类单元将来自感兴趣像素的亮度变化的亮度变化平均值与感兴趣像素周围的相邻像素的上阈值和下阈值进行比较，并将感兴趣像素的亮度变化水平分类为 根据比较结果的三种类型。 基于感兴趣像素的亮度来预定上限阈值和下阈值。 动态权重计算单元根据感兴趣像素的亮度变化等级来计算不同的动态权重。 亮度校正单元基于动态权重校正感兴趣像素的亮度。 因此，在图像的平面部分产生的噪声被最小化，并且图像的轮廓被适当地加强，从而改善了图像的定义。

公开(公告)号：US08051932B2

公开(公告)日：2011-11-08

申请号：US12231694

申请日：2008-09-05

申请人： Joon Young Park

发明人： Joon Young Park

IPC分类号： B60K6/20

CPC分类号： B60W20/13 ,  B60K6/20 ,  B60W10/06 ,  B60W10/08 ,  B60W10/26 ,  B60W20/00 ,  B60W30/1882 ,  B60W30/1886 ,  B60W2510/244 ,  B60W2520/10 ,  B60W2540/10 ,  Y02T10/56 ,  Y02T10/6269 ,  Y02T10/6286 ,  Y02T10/84

摘要： The present invention provides a method of compensating for auxiliary loads of a hybrid vehicle, which divides the auxiliary loads into a mechanical auxiliary load and an electrical auxiliary load and performs an appropriate auxiliary load compensation according to the kind of auxiliary loads, thus improving system efficiency as well as power performance of the vehicle.

摘要翻译： 本发明提供一种补偿混合动力车辆的辅助负载的方法，其将辅助负载分为机械辅助负载和辅助负载，并根据辅助负载的种类进行适当的辅助负载补偿，从而提高系统效率 以及车辆的动力性能。

公开(公告)号：USD647820S1

公开(公告)日：2011-11-01

申请号：US29373752

申请日：2011-05-18

申请人： Yong-Pil Jang

设计人： Yong-Pil Jang

公开(公告)号：US08048483B2

公开(公告)日：2011-11-01

申请号：US11783048

申请日：2007-04-05

申请人： Soon-Gil Yoon ,  Nak-Jin Seong ,  Sang-Yong Jeon

发明人： Soon-Gil Yoon ,  Nak-Jin Seong ,  Sang-Yong Jeon

IPC分类号： B05D3/00

CPC分类号： B05D3/00 ,  C23C16/40 ,  C23C16/45565 ,  H05K3/146

摘要： A method to deposit a thin film on a flexible polymer substrate at room temperature comprising heating source vapor, which is vaporized by an evaporator, in a shower head in a reaction chamber so that the source vapor is thermally decomposed to be converted into the nano-size single phase; and depositing the source vapor in the nano-size single phase on the flexible polymer substrate which is not separately heated.

摘要翻译： 一种在室温下在柔性聚合物基材上沉积薄膜的方法，包括在蒸发器中蒸发的加热源蒸气在反应室中的喷淋头中，使得源蒸气被热分解以转化为纳米 - 尺寸单相; 以及将纳米尺寸单相中的源蒸气沉积在未分开加热的柔性聚合物基底上。

公开(公告)号：US08040279B2

公开(公告)日：2011-10-18

申请号：US12183027

申请日：2008-07-30

申请人： Yung-Hoon Jo

发明人： Yung-Hoon Jo

IPC分类号： G01S5/02

CPC分类号： G01S5/12 ,  G01S5/021 ,  G01S5/0215

摘要： Techniques, systems and computer readable medium are disclosed for measuring a position of an object device. A position measuring apparatus includes a receiving unit designed to receive a signal transmitted from an object device for position measurement. The position measuring apparatus also includes a position computing unit designed to compute a position of the object device by applying Angle Of Arrival (AOA) and Time Of Arrival (TOA) techniques using the received signal. The position measuring apparatus also includes a medium channel estimating unit designed to estimate a channel of a medium, through which the received signal penetrates on a transmission path, using the received signal. The position measuring apparatus also includes a position correcting unit configured to compute a delay time caused by the received signal penetrating the medium using the estimated medium channel and correcting the position of the object device computed by the position computing unit using the delay time.

摘要翻译： 公开了用于测量对象设备的位置的技术，系统和计算机可读介质。 位置测量装置包括：接收单元，被设计成接收从对象装置发送的用于位置测量的信号。 位置测量装置还包括位置计算单元，其被设计成通过使用接收信号应用到达角（AOA）和到达时间（TOA）技术来计算对象设备的位置。 位置测量装置还包括介质信道估计单元，其被设计为使用接收信号估计接收信号穿过传输路径的介质的信道。 位置测量装置还包括：位置校正单元，被配置为使用所估计的介质通道来计算由穿透介质的接收信号引起的延迟时间，并且使用延迟时间来校正由位置计算单元计算的对象设备的位置。