摘要:
The present subject matter provides a method for delivering a gene editing composition across a plasma membrane of a cell. Related apparatus, system, techniques, compositions, and articles are also described.
摘要:
The invention relates to fluid distribution in an exposure device. The exposure device, in some examples, is a device for exposing living cell cultures or cellular tissues to a fluid such as cigarette smoke, air and/or other gases or gas mixtures, for use in studies of the effects on the cell cultures or tissues of their exposure to the fluid. A fluid distribution member is described for distributing the fluid in the exposure device, the member including a plurality of apertures in a surface arranged such that, when the distribution member is fitted to the fluid exposure device, the distribution member receives fluid applied to the surface of the member and distributes the fluid, via the apertures, to samples to be exposed to the fluid in the exposure device.
摘要:
A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.
摘要:
A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.
摘要:
A sampling system for providing a sample plug 70 from a fluid sample, comprising: a flow channel through which a flow of a fluid sample is passed; plasma generators 12 and 14; and a control unit configured to drive the plasma generator 12 at a power level at which the fluid sample is modified by the plasma P1 and interrupt busy the plasma P1 for a period of time such as to allow a plug of the fluid sample to pass downstream thereof. The volume of the plug 70 is determined by the time period during which the plasma P1 is interrupted. With the plasma P1 being maintained, the components of the plug 70 separate on transit through a separation channel 10. These components pass through the second plasma P2, and the emissions generated are detected by an optical detector 16.
摘要:
A device for demonstrating the operation of gas contaminant testing apparatus and for training persons to use such apparatus. The device can be portable and allows demonstration of and training on testing apparatus in a location removed from the environment in which the gaseous medium and its gaseous and vaporous contaminants are normally found. The device uses very small contaminant samples for demonstration in order to minimize personnel exposure and inadvertent or deliberate releases to the environment. The device allows the substitutions of, for training and demonstration purposes, a harmless gaseous medium for the actual gaseous medium of interest. In a preferred embodiment, designed for demonstrating the operation of a refrigerant contaminant testing apparatus, air is susbstituted for refrigerant as the gaseous medium in which contaminants are entrained when using the device. In that embodiment, air is caused to flow through a container holding a contaminant sample of interest. Vapors of the contaminant mix with the air and the mixture is caused to flow through a refrigerant contaminant testing tube connected to the device, resulting in testing tube indications that emulate the indications to be expected when testing a refrigerant sample containing the contaminant. More than one sample container can be fitted into the device and there can be one or more tester connections. The sample containers are interchangeable so that demonstrating a variety of contaminants is possible. The device may be used as an adjunct to gas testing apparatus for testing a gas sample collected at a remote location.
摘要:
Accordingly, the present invention is an apparatus for mixing gas and air to obtain a plurality of predetermined gas-air concentrations including means for supplying gas from a constant pressure gas source. A conduit has a first end connected to the supplying means and a second end connected to a means for diffusing air with the gas to obtain a predetermined gas-air concentration.
摘要:
A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.
摘要:
A cartridge for dispensing a fluid is presented. The cartridge comprises a reservoir chamber for receiving the fluid and for receiving a ventilation gas. The reservoir chamber comprises an inlet for receiving the ventilation gas and an outlet for dispensing the fluid. At least a portion of the reservoir chamber is filled with the ventilation gas when in an operating position. The inlet is located in the portion being filled with the ventilation gas. The fluid comprises a reagent. The cartridge further comprises a baffle for restricting gas diffusion through the inlet. The reservoir chamber receives the ventilation gas via the baffle. The inlet is maintains a constant gas pressure within the portion of the reservoir chamber that is being filled with the ventilation gas.
摘要:
A microchannel chip having a microchannel formed in a substrate and a gas-liquid phase separation microchannel whose upper part is covered with a porous film, the gas-liquid phase separation microchannel being connected to the downstream end of the microchannel and having a depth of 10 μm to 100 μm. Also, a gas-liquid phase separation method which is a method for separating a liquid-phase flow from a two-phase flow flowing through a microchannel by removing a gas phase, the two-phase flow composed of the gas phase and the liquid phase, which liquid phase flows in the periphery of the above-described microchannel and which gas phase flows interiorly of the liquid-phase flow.