公开(公告)号：US08343478B2

公开(公告)日：2013-01-01

申请号：US11652937

申请日：2007-01-11

申请人： Daniela Paulsen ,  Helga Ruebsamen-Schaeff ,  Amar Kureishi ,  Gerhard Hunsmann ,  Christiane Stahl-Hennig ,  Andreas Meyerhans ,  Alexandra Schuetz ,  Olaf Weber

发明人： Daniela Paulsen ,  Helga Ruebsamen-Schaeff ,  Amar Kureishi ,  Gerhard Hunsmann ,  Christiane Stahl-Hennig ,  Andreas Meyerhans ,  Alexandra Schuetz ,  Olaf Weber

IPC分类号： A61K39/155 ,  A61K31/711 ,  A61K38/00

CPC分类号： A61K45/06 ,  A61K31/70 ,  A61K35/76 ,  C12N2710/24232 ,  C12N2740/15011 ,  C12N2740/16011 ,  A61K2300/00

摘要： The present invention relates to the use of Parapoxviruses in combination with other agents for the treatment of viral diseases, and in particular HIV infections and AIDS. The invention also relates to methods for producing medicaments based on combinations of Parapoxviruses and other antiviral agents, and to such medicaments. In particular, the invention relates to the use of Parapoxviruses in combination with agents of the kind used for antiretroviral therapy and highly active antiretroviral therapy (HAART).

摘要翻译： 本发明涉及与其它药剂组合用于治疗病毒性疾病，特别是HIV感染和AIDS的副作用病毒的用途。 本发明还涉及基于对痘病毒和其它抗病毒剂的组合制备药物的方法以及这些药物。 特别地，本发明涉及副作用病毒与用于抗逆转录病毒治疗和高活性抗逆转录病毒治疗（HAART）的药物的组合的使用。

公开(公告)号：US20100255032A1

公开(公告)日：2010-10-07

申请号：US11652937

申请日：2007-01-11

申请人： Daniela Paulsen ,  Helga Ruebsamen-Schaeff ,  Amar Kureishi ,  Gerhard Hunsmann ,  Christiane Stahl-Hennig ,  Andreas Meyerhans ,  Alexandra Schuetz ,  Olaf Weber

发明人： Daniela Paulsen ,  Helga Ruebsamen-Schaeff ,  Amar Kureishi ,  Gerhard Hunsmann ,  Christiane Stahl-Hennig ,  Andreas Meyerhans ,  Alexandra Schuetz ,  Olaf Weber

IPC分类号： A61K39/275 ,  A61P31/18

CPC分类号： A61K45/06 ,  A61K31/70 ,  A61K35/76 ,  C12N2710/24232 ,  C12N2740/15011 ,  C12N2740/16011 ,  A61K2300/00

摘要： The present invention relates to the use of Parapoxviruses in combination with other agents for the treatment of viral diseases, and in particular HIV infections and AIDS. The invention also relates to methods for producing medicaments based on combinations of Parapoxviruses and other antiviral agents, and to such medicaments. In particular, the invention relates to the use of Parapoxviruses in combination with agents of the kind used for antiretroviral therapy and highly active antiretroviral therapy (HAART).

摘要翻译： 本发明涉及与其它药剂组合用于治疗病毒性疾病，特别是HIV感染和AIDS的副作用病毒的用途。 本发明还涉及基于对痘病毒和其它抗病毒剂的组合制备药物的方法以及这些药物。 特别地，本发明涉及副作用病毒与用于抗逆转录病毒治疗和高活性抗逆转录病毒治疗（HAART）的药物的组合的使用。

公开(公告)号：US4997927A

公开(公告)日：1991-03-05

申请号：US770295

申请日：1985-08-27

申请人： Helmut Blocker ,  Ronald Frank ,  Gudrun Heisterberg-Moutsis ,  Gisela Kurth ,  Andreas Meyerhans

发明人： Helmut Blocker ,  Ronald Frank ,  Gudrun Heisterberg-Moutsis ,  Gisela Kurth ,  Andreas Meyerhans

IPC分类号： C07H1/06 ,  C07H21/00 ,  C07H21/04

CPC分类号： C07H21/00 ,  Y02P20/55

摘要： A process for the purfication of synthetic oligonucleotides is described which drastically simplifies the hitherto very time consuming purification process. The deprotection solution is adsorbed without being concentrated on a carrier having reversed phase properties and optionally ion exchanger properties, the oligonuleotides without lipophilic protecting group are removed, their protecting group is cleaved off from the adsorbed oligonucleotides, the adsorbed oligonucleotides are washed and eluted from the carrier and then purified in a manner known per se.

摘要翻译： 描述了合成寡核苷酸的纯化方法，其大大简化了迄今非常耗时的纯化过程。 将脱保护溶液吸附而不被浓缩在具有反相特性和任选离子交换性质的载体上，除去没有亲脂性保护基团的寡核苷酸，将其保护基从吸附的寡核苷酸上切下，将吸附的寡核苷酸从 载体，然后以本身已知的方式纯化。

公开(公告)号：US06673255B2

公开(公告)日：2004-01-06

申请号：US09925646

申请日：2001-08-10

申请人： Alexander Marxer ,  Andreas Meyerhans ,  Fredy Zuend

发明人： Alexander Marxer ,  Andreas Meyerhans ,  Fredy Zuend

IPC分类号： B01J1500

CPC分类号： C23C16/54 ,  C23C14/566 ,  C23C16/44 ,  C23C16/4401 ,  H01J37/32743 ,  H01L21/67201 ,  H01L21/67745 ,  H01L21/67748 ,  H01L21/67754 ,  Y10S414/135 ,  Y10S414/139

摘要： An apparatus for plasma treating workpieces in vacuum comprises a stack of plasma chambers (20). Handling of workpieces to and from the plasma chambers of the stack is performed in parallelism by one handling device and through lateral handling openings of the plasma chambers. The handling device is rotatable around an axis parallel to the handling openings of the plasma chambers and comprises transport means simultaneously movable radially with respect to the axis of rotation towards and from the handling openings.

摘要翻译： 用于在真空中等离子体处理工件的装置包括一叠等离子体室（20）。 通过一个处理装置并通过等离子体室的横向处理开口并行地执行工件到堆叠的等离子体室的处理。 处理装置可绕平行于等离子体室的处理开口的轴线旋转，并且包括可相对于旋转轴线径向相对于处理开口径向移动的输送装置。

公开(公告)号：US06296735B1

公开(公告)日：2001-10-02

申请号：US09177894

申请日：1998-10-23

申请人： Alexander Marxer ,  Andreas Meyerhans ,  Fredy Zuend

发明人： Alexander Marxer ,  Andreas Meyerhans ,  Fredy Zuend

IPC分类号： H05H100

CPC分类号： C23C16/54 ,  C23C14/566 ,  C23C16/44 ,  C23C16/4401 ,  H01J37/32743 ,  H01L21/67201 ,  H01L21/67745 ,  H01L21/67748 ,  H01L21/67754 ,  Y10S414/135 ,  Y10S414/139

摘要： An apparatus for plasma treating workpieces in vacuum comprises a stack of plasma chambers (20). Handling of workpieces to and from the plasma chambers of the stack is performed in parellelism by one handling device and through lateral handling openings of the plasma chambers. The handling device is rotatable around an axis parallel to the handling openings of the plasma chambers and comprises transport means simultaneously movable radially with respect to the axis of rotation towards and from the handling openings.

摘要翻译： 用于在真空中等离子体处理工件的装置包括一叠等离子体室（20）。 工件往复堆叠的等离子体室的处理通过一个处理装置并通过等离子体室的横向处理开口以平行方式进行。 处理装置可绕平行于等离子体室的处理开口的轴线旋转，并且包括可相对于旋转轴线径向相对于处理开口径向移动的输送装置。