Antibodies and methods for making and using them
    1.
    发明授权
    Antibodies and methods for making and using them 有权
    用于制造和使用它们的抗体和方法

    公开(公告)号:US08465741B2

    公开(公告)日:2013-06-18

    申请号:US11855943

    申请日:2007-09-14

    摘要: The invention provides antibodies, including chimeric human antibodies, recombinant antibodies, synthetic antibodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypeptides comprising, or consisting of, consensus human framework regions, or “Independently Consensused Frameworks (ICFs)”, nucleic acids encoding them, and libraries and kits comprising these ICFs and/or antibodies of the invention, individually and in combinatorial libraries and combinations.

    摘要翻译: 本发明提供抗体,包括嵌合人抗体,重组抗体,合成抗体和编码它们的核酸,以及制备和使用这些免疫球蛋白的方法。 本发明提供这些多肽和/或抗体的重组和合成多肽和核酸实施方案。 本发明还提供了包含共有人框架区或“独立共有框架(ICF)”的编码它们的核酸或包含本发明的这些ICF和/或抗体的文库和试剂盒的多肽,并且组合的多肽 图书馆和组合。

    ANTIBODIES AND METHODS FOR MAKING AND USING THEM
    3.
    发明申请
    ANTIBODIES AND METHODS FOR MAKING AND USING THEM 有权
    用于制造和使用它们的抗体和方法

    公开(公告)号:US20100104553A1

    公开(公告)日:2010-04-29

    申请号:US11855943

    申请日:2007-09-14

    摘要: The invention provides antibodies, including chimeric human antibodies, recombinant antibodies, synthetic antibodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypeptides comprising, or consisting of, consensus human framework regions, or “Independently Consensused Frameworks (ICFs)”, nucleic acids encoding them, and libraries and kits comprising these ICFs and/or antibodies of the invention, individually and in combinatorial libraries and combinations.

    摘要翻译: 本发明提供抗体,包括嵌合人抗体,重组抗体,合成抗体和编码它们的核酸,以及制备和使用这些免疫球蛋白的方法。 本发明提供这些多肽和/或抗体的重组和合成多肽和核酸实施方案。 本发明还提供了包含共有人框架区或“独立共有框架(ICF)”的编码它们的核酸或包含本发明的这些ICF和/或抗体的文库和试剂盒的多肽,并且组合的多肽 图书馆和组合。

    Antibodies and methods for making and using them
    5.
    发明授权
    Antibodies and methods for making and using them 有权
    用于制造和使用它们的抗体和方法

    公开(公告)号:US08945550B2

    公开(公告)日:2015-02-03

    申请号:US12487422

    申请日:2009-06-18

    IPC分类号: A61K39/395

    摘要: The invention provides antibodies, including chimeric human antibodies, recombinant antibodies, synthetic anti-bodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypeptides comprising, or consisting of, consensus human framework regions, or “Independently Consensused Frameworks (ICFs)”, nucleic acids encoding them, and libraries and kits comprising these ICFs and/or antibodies of the invention, individually and in combinatorial libraries and combinations.

    摘要翻译: 本发明提供抗体,包括嵌合人抗体,重组抗体,合成抗体和编码它们的核酸,以及制备和使用这些免疫球蛋白的方法。 本发明提供这些多肽和/或抗体的重组和合成多肽和核酸实施方案。 本发明还提供了包含共有人框架区或“独立共有框架(ICF)”的编码它们的核酸或包含本发明的这些ICF和/或抗体的文库和试剂盒的多肽,并且组合的多肽 图书馆和组合。