公开(公告)号：US20190142303A1

公开(公告)日：2019-05-16

申请号：US16008594

申请日：2018-06-14

申请人： Capnia, Inc.

发明人： Anthony D. WONDKA ,  Anish BHATNAGAR

IPC分类号： A61B5/097 ,  A61B5/08

摘要： Breath analysis systems and methods test for infectious diseases in exhaled breath gas or condensate. An automatic breath sampling system can obtain reliable samples over a variety of clinical situations. In some variations, the system is modular system and can protect the equipment and clinician from contamination. In some variations, the system can be a point-of-care rapid-result instrument. In some variations, can be configured for off-line analysis in which case the collected sample is presented to a stand-alone analyzer for measurement.

公开(公告)号：US20170157348A1

公开(公告)日：2017-06-08

申请号：US15368328

申请日：2016-12-02

申请人： Capnia, Inc.

发明人： Constantine Andrew GILLESPIE ,  Otho Newman BOONE ,  Pedro E. DE LA SERNA ,  Anthony D. WONDKA

IPC分类号： A61M16/00 ,  A61M16/12 ,  A61M16/06 ,  A61M16/08

CPC分类号： A61M16/0078 ,  A61M16/0003 ,  A61M16/0075 ,  A61M16/0081 ,  A61M16/0084 ,  A61M16/06 ,  A61M16/0816 ,  A61M16/125 ,  A61M16/208 ,  A61M2202/0208 ,  A61M2205/3379 ,  A61M2240/00 ,  A61M2202/0007

摘要： Resuscitation apparatuses and methods for assisted ventilation are described herein. The apparatuses may include functional elements that allow the manual delivery of a prescribed volume to an adult or an infant lung. Furthermore, the apparatuses may inform and assure an emergency worker that an appropriate volume is being delivered and therefore lessen the possibility of barotrauma from over-delivery, or ventilatory distress from under-delivery. In some embodiments, the apparatuses include biomechanical and ergonomic functional elements that allow an adult hand to hold it in place during operation, while at the same time, allowing the user to actuate the apparatus to deliver only the necessary amount of volume suitable for an infant lung. In other embodiments, a volume-controlled design is applied to pediatric and adult resuscitation.

公开(公告)号：US20160106343A1

公开(公告)日：2016-04-21

申请号：US14918484

申请日：2015-10-20

申请人： Capnia, Inc.

发明人： Anthony D. WONDKA ,  Anish BHATNAGAR

IPC分类号： A61B5/097 ,  A61B5/00 ,  A61B5/08

CPC分类号： A61B5/097 ,  A61B5/0816 ,  A61B5/082 ,  A61B5/749 ,  A61B2560/0443

摘要： Breath analysis systems and methods test for infectious diseases in exhaled breath gas or condensate. An automatic breath sampling system can obtain reliable samples over a variety of clinical situations. In some variations, the system is modular system and can protect the equipment and clinician from contamination. In some variations, the system can be a point-of-care rapid-result instrument. In some variations, can be configured for off-line analysis in which case the collected sample is presented to a stand-alone analyzer for measurement.

摘要翻译： 呼吸分析系统和方法测试呼出气体或冷凝物中的传染病。 自动呼吸采样系统可以在各种临床情况下获得可靠的样品。 在一些变型中，系统是模块化系统，可以保护设备和临床医生免受污染。 在一些变体中，该系统可以是一个关键的快速结果仪器。 在一些变型中，可以配置为离线分析，在这种情况下，将收集的样品提供给独立分析仪进行测量。

公开(公告)号：US20200046254A1

公开(公告)日：2020-02-13

申请号：US16386034

申请日：2019-04-16

申请人： Capnia, Inc.

发明人： Anthony D. WONDKA ,  Anish BHATNAGAR

IPC分类号： A61B5/08 ,  A61B5/097 ,  A61B5/00

摘要： Methods and systems are described to automatically obtain and analyze a lung airway gas sample from the breath of a person for compositional analysis. These techniques may provide an improved method for example for accurately and reliably measuring nitric oxide for asthma assessment in young children and non-cognizant patients.

公开(公告)号：US09936897B2

公开(公告)日：2018-04-10

申请号：US14812822

申请日：2015-07-29

申请人： Capnia, Inc.

发明人： Lee R. Carlson ,  Edward A. McClatchie ,  Joe Martinosky ,  Ralph Walden ,  Elvir Causevic

IPC分类号： A61B5/08 ,  A61B5/097 ,  A61B5/083 ,  A61B5/087

CPC分类号： A61B5/097 ,  A61B5/08 ,  A61B5/082 ,  A61B5/083 ,  A61B5/0833 ,  A61B5/0836 ,  A61B5/087

摘要： An improved apparatus and method for capturing and analyzing the end-tidal portion of an exhalation. The CO2 level of air drawn into the system (10) is monitored to distinguish inhalation and exhalation of breath. Upon detection of a decrease in the CO2 level in the air drawn into the system (10), indicating a transition between exhalation and inhalation a pair of flow selector valves (26, 28) are operated to capture the end-tidal volume of air drawn into the system (10) immediately prior to the detection of the decrease in the CO2 level. Incoming air is diverted around the captured volume of air, and the CO2 levels are continually monitored to ensure that the captured volume of air corresponds to the end-tidal portion of an exhalation. Once the captured volume of air is positively identified as the end-tidal portion of an exhalation, the captured volume is routed through a gas analyzer (44) for analysis of one or more predetermined gas levels.

公开(公告)号：US20160060355A1

公开(公告)日：2016-03-03

申请号：US14838241

申请日：2015-08-27

申请人： Capnia, Inc.

发明人： Anish BHATNAGAR ,  Anthony D. WONDKA

IPC分类号： C07K16/34 ,  A61B5/083 ,  A61B5/00 ,  G01N33/497

摘要： Methods for administering immune globulin and devices for use thereof. The methods may generally include measuring a patient's hemolysis levels and determining whether the patient is suitable for immune globulin treatment, determining whether immune globulin treatment should be continued, and/or determining if the dose needs to be changed.

摘要翻译： 免疫球蛋白的给药方法及其使用的装置。 所述方法通常可以包括测量患者的溶血水平并确定患者是否适合于免疫球蛋白治疗，确定是否应持续免疫球蛋白治疗和/或确定是否需要改变剂量。

公开(公告)号：US20150265184A1

公开(公告)日：2015-09-24

申请号：US14664728

申请日：2015-03-20

申请人： Capnia, Inc.

发明人： Anthony D. WONDKA ,  Anish BHATNAGAR

IPC分类号： A61B5/08 ,  A61B5/00 ,  A61B5/097

CPC分类号： A61B5/082 ,  A61B5/0816 ,  A61B5/0836 ,  A61B5/087 ,  A61B5/097 ,  A61B5/6803 ,  A61B5/6819 ,  A61B5/682 ,  A61B5/7221 ,  A61B5/74 ,  A61B2503/04 ,  A61B2503/06

摘要： Methods and systems are described to automatically obtain and analyze a lung airway gas sample from the breath of a person for compositional analysis. These techniques may provide an improved method for example for accurately and reliably measuring nitric oxide for asthma assessment in young children and non-cognizant patients.

摘要翻译： 描述了方法和系统，以便从人的呼吸中自动获得和分析肺气道气体样品用于组成分析。 这些技术可以提供一种改进的方法，例如准确可靠地测量一氧化氮用于儿童和非识别患者的哮喘评估。

公开(公告)号：US20150065901A1

公开(公告)日：2015-03-05

申请号：US14473878

申请日：2014-08-29

申请人： Capnia, Inc.

发明人： Anish BHATNAGAR ,  Anthony D. WONDKA

IPC分类号： A61B5/097 ,  A61B5/08

摘要： A breath analysis device is described which obtains a desired segment of one or more breaths, and analyzes that or those samples for compositional analysis. A pneumatic control system may obtain these segments homogeneously, may reduce the amount of gases included from other segments of the breath, and may reduce mixing with other segments once obtained. These pneumatic control systems can be used for on-board compositional analysis, or for modular or off-board compositional analysis.

摘要翻译： 描述了一种呼气分析装置，其获得一个或多个呼吸的期望区段，并分析那些或那些用于组成分析的样品。 气动控制系统可以均匀地获得这些部分，可以减少从呼吸的其他部分包括的气体的量，并且可以减少一旦获得的与其它部分的混合。 这些气动控制系统可用于车载成分分析，也可用于模块化或车外成分分析。

公开(公告)号：US20130331769A1

公开(公告)日：2013-12-12

申请号：US13685213

申请日：2012-11-26

申请人： Capnia, Inc.

发明人： Ned S. RASOR ,  Julia S. RASOR

IPC分类号： A61M31/00

CPC分类号： A61M31/00 ,  A61H33/14 ,  A61H2033/145 ,  A61M11/04 ,  A61M11/047 ,  A61M15/0041 ,  A61M15/0065 ,  A61M15/009 ,  A61M37/00 ,  A61M2202/0007 ,  A61M2202/0225 ,  A61M2202/064 ,  A61M2205/8225

摘要： Apparatus, methods, and kits for treating symptoms associated with common ailments, such as headaches, rhinitis, asthma, epilepsy, nervous disorders and the like, are provided. The apparatus comprises dispensers for carbon dioxide and other therapeutic gases. The methods comprise delivering small volumes of these gases to patients in a manner where the gas infuses into a body region in order to bathe the mucous membranes therein. It has been found that even very short exposure of patients to small volumes and high concentrations of such gases can provide significant relief from symptoms.

摘要翻译： 提供了用于治疗与常见疾病相关的症状的装置，方法和试剂盒，例如头痛，鼻炎，哮喘，癫痫，神经障碍等。 该装置包括用于二氧化碳和其它治疗气体的分配器。 这些方法包括以气体输入体内区域的方式向患者输送小量的这些气体，以便将其中的粘膜沐浴。 已经发现，即使非常短的患者暴露于小体积和高浓度的这种气体也可以显着缓解症状。

公开(公告)号：US20210015424A1

公开(公告)日：2021-01-21

申请号：US16799178

申请日：2020-02-24

申请人： Capnia, Inc.

发明人： Anish BHATNAGAR ,  Anthony D. WONDKA

IPC分类号： A61B5/00 ,  G01N33/497 ,  A61B5/08

摘要： Methods for administering immune globulin and devices for use thereof. The methods may generally include measuring a patient's hemolysis levels and determining whether the patient is suitable for immune globulin treatment, determining whether immune globulin treatment should be continued, and/or determining if the dose needs to be changed.