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1.
公开(公告)号:US09827216B2
公开(公告)日:2017-11-28
申请号:US13063589
申请日:2009-09-11
申请人: Eduardo Schiffrin , Kevin Burke Miller , Dominique Brassart , Olivier Jacques Lantz , Sebastian Diego Amigorena
发明人: Eduardo Schiffrin , Kevin Burke Miller , Dominique Brassart , Olivier Jacques Lantz , Sebastian Diego Amigorena
IPC分类号: A61K31/20 , A61K31/195 , A61K31/7088 , A61K35/747 , A61K38/40 , A61K38/01 , A61K35/745 , A61K38/17 , A61K33/00 , A23L33/00 , A23L33/13 , A23L33/135 , A23L33/175 , A23L33/19
CPC分类号: A61K31/195 , A23L33/13 , A23L33/135 , A23L33/175 , A23L33/19 , A23L33/40 , A23V2002/00 , A61K31/20 , A61K31/7088 , A61K33/00 , A61K35/745 , A61K35/747 , A61K38/018 , A61K38/1783 , A61K38/40 , A23V2200/306
摘要: The present invention relates to methods and immunonutritional compositions for preventing or mitigating paralysis of the bone marrow, caused by a tumor or neoplasm, between cycles of and after anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to methods and immunonutritional compositions that can transiently preventing or moderating, bone marrow paralysis or neutropenia of a subject tumor-induced apoptosis or necrosis or other cell damage such that the innate and adaptive immune functions and normal physiology of the bone marrow are preserved, at least in part, which, in turn, lead to (i) a better tolerance and increased efficacy to treatment; (ii) transient augmentation or enhancement of immunocompetence of the immune cell; and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened due to paralysis of the bone marrow, caused by a tumor or neoplasm.
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公开(公告)号:US08771675B2
公开(公告)日:2014-07-08
申请号:US12053037
申请日:2008-03-21
申请人: Ralf Zink , Roberto Reniero , Florence Rochat , Christoph Cavadini , Thierry Von Der Weid , Eduardo Schiffrin , Jalil Benyacoub , Virginie Rousseau , Pablo Perez , Ruth Knorr
发明人: Ralf Zink , Roberto Reniero , Florence Rochat , Christoph Cavadini , Thierry Von Der Weid , Eduardo Schiffrin , Jalil Benyacoub , Virginie Rousseau , Pablo Perez , Ruth Knorr
CPC分类号: C12R1/225 , A23K10/18 , A23K50/42 , A23K50/48 , A61K35/744 , A61K35/745 , A61K35/747 , C12R1/23 , C12R1/46 , Y10S426/805
摘要: The present invention provides novel strains of probiotics for use in the gastrointestinal tract of a pet. The probiotics of the present invention are capable of fermenting starch to produce lactic acid and/or hydrogen peroxide anti-pathogenic metabolites. The present invention also provides a novel method for identifying the effectiveness of a pet probiotic in vitro. The method simulates the introduction of a probiotic candidate in the gastrointestinal tract of a pet and measures the anti-pathogenic effectiveness of the probiotic.
摘要翻译: 本发明提供用于宠物胃肠道中的益生菌的新菌株。 本发明的益生菌能够发酵淀粉以产生乳酸和/或过氧化氢抗病原代谢物。 本发明还提供了一种用于鉴定宠物益生菌在体外的有效性的新方法。 该方法模拟在宠物的胃肠道中引入益生菌候选物并测量益生菌的抗病原效力。
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公开(公告)号:US20100135971A1
公开(公告)日:2010-06-03
申请号:US12598905
申请日:2008-05-14
申请人: Eduardo Schiffrin
发明人: Eduardo Schiffrin
CPC分类号: A61K35/747 , A23L33/135 , A61K35/745 , A61K2300/00
摘要: The present invention relates generally to the field of nutrition, more particularly to the use of probiotics in nutrition. In particular the present invention relates to the use of a probiotic or of a mixture of probiotics in the manufacture of a nutritional composition or a medicament to act the colon in a pre- or post surgical environment.
摘要翻译: 本发明一般涉及营养领域,更具体地涉及益生菌在营养中的应用。 特别地,本发明涉及益生菌或益生菌混合物在制造营养组合物或药物中在手术前或手术后环境中作用的用途。
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公开(公告)号:US20080171106A1
公开(公告)日:2008-07-17
申请号:US12053037
申请日:2008-03-21
申请人: Ralf Zink , Roberto Reniero , Florence Rochat , Christoph Cavadini , Thierry Von Der Weid , Eduardo Schiffrin , Jalil Benyacoub , Virginie Rousseau , Pablo Perez , Ruth Knorr
发明人: Ralf Zink , Roberto Reniero , Florence Rochat , Christoph Cavadini , Thierry Von Der Weid , Eduardo Schiffrin , Jalil Benyacoub , Virginie Rousseau , Pablo Perez , Ruth Knorr
IPC分类号: A23K1/00
CPC分类号: C12R1/225 , A23K10/18 , A23K50/42 , A23K50/48 , A61K35/744 , A61K35/745 , A61K35/747 , C12R1/23 , C12R1/46 , Y10S426/805
摘要: The present invention provides novel strains of probiotics for use in the gastrointestinal tract of a pet. The probiotics of the present invention are capable of fermenting starch to produce lactic acid and/or hydrogen peroxide anti-pathogenic metabolites. The present invention also provides a novel method for identifying the effectiveness of a pet probiotic in vitro. The method simulates the introduction of a probiotic candidate in the gastrointestinal tract of a pet and measures the anti-pathogenic effectiveness of the probiotic.
摘要翻译: 本发明提供用于宠物胃肠道中的益生菌的新菌株。 本发明的益生菌能够发酵淀粉以产生乳酸和/或过氧化氢抗病原代谢物。 本发明还提供了一种用于鉴定宠物益生菌在体外的有效性的新方法。 该方法模拟在宠物的胃肠道中引入益生菌候选物并测量益生菌的抗病原效力。
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公开(公告)号:US07189390B2
公开(公告)日:2007-03-13
申请号:US10296070
申请日:2001-05-22
申请人: Ralf Zink , Roberto Reniero , Florence Rochat , Christoph Cavadini , Thierry Der Weid , Eduardo Schiffrin , Jalil Benyacoub , Virginie Rousseau , Pablo Perez
发明人: Ralf Zink , Roberto Reniero , Florence Rochat , Christoph Cavadini , Thierry Der Weid , Eduardo Schiffrin , Jalil Benyacoub , Virginie Rousseau , Pablo Perez
CPC分类号: C12R1/225 , A23K10/18 , A23K50/42 , A23K50/48 , A61K35/744 , A61K35/745 , A61K35/747 , C12R1/23 , C12R1/46 , Y10S426/805
摘要: The present invention relates to novel lactic acid bacterial micro-organisms that have been isolated and selected for their probiotic potential and their use for the preparation of petfood compositions intended to improve the health of pets, and to compositions containing the same.
摘要翻译: 本发明涉及由益生菌潜力分离和选择的新型乳酸菌微生物及其用于制备旨在改善宠物健康的宠物食品组合物的用途,以及含有该宠物的组合物。
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6.
公开(公告)号:US20050186191A1
公开(公告)日:2005-08-25
申请号:US11111255
申请日:2005-04-20
申请人: Eduardo Schiffrin , Pablo Perez
发明人: Eduardo Schiffrin , Pablo Perez
CPC分类号: C12R1/01 , A23C9/1234 , A23C9/1236 , A23L29/065 , A61K35/745 , A61K35/747 , Y02A50/491
摘要: The present invention relates to the use of a supernatant of lactic acid bacteria or of Bifidobacteria capable of preventing colonization of intestinal cells by Giardia intestinalis, for the preparation of an ingestible carrier for the treatment and/or prophylaxis of disorders associated with the colonization of the gut by Giardia intestinalis. The present invention also pertains to specific strains of Bifidobacterium having the above traits and to the ingestible carrier, such as a food or pharmaceutical composition, containing such supernatant or the microorganisms.
摘要翻译: 本发明涉及乳酸菌或双歧杆菌的上清液的用途,所述双歧杆菌能够预防肠梗阻引起的肠细胞的定殖,用于制备可摄取的载体,用于治疗和/或预防与 肠道由贾第鞭毛虫肠道 本发明还涉及具有上述性状的双歧杆菌和含有这种上清液或微生物的可摄入载体,例如食品或药物组合物的具体菌株。
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公开(公告)号:US08529887B2
公开(公告)日:2013-09-10
申请号:US12598905
申请日:2008-05-14
申请人: Eduardo Schiffrin
发明人: Eduardo Schiffrin
CPC分类号: A61K35/747 , A23L33/135 , A61K35/745 , A61K2300/00
摘要: The present invention relates generally to the field of nutrition, more particularly to the use of probiotics in nutrition. In particular the present invention relates to the use of a probiotic or of a mixture of probiotics in the manufacture of a nutritional composition or a medicament to act the colon in a pre- or post surgical environment.
摘要翻译: 本发明一般涉及营养领域,更具体地涉及益生菌在营养中的应用。 特别地,本发明涉及益生菌或益生菌混合物在制造营养组合物或药物中在手术前或手术后环境中作用的用途。
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公开(公告)号:US07964384B2
公开(公告)日:2011-06-21
申请号:US12488293
申请日:2009-06-19
CPC分类号: A61K35/747 , A61K35/745 , Y10S435/853 , Y10S435/854
摘要: The invention relates to the use of at least one strain of lactic acid bacteria and/or bifidobacteria having hydrophobic surface properties, for the preparation of a composition intended for the prevention or the treatment of endotoxin mediated and/or associated disorders and human or pet food compositions prepared thereof.
摘要翻译: 本发明涉及至少一种具有疏水表面性质的乳酸菌和/或双歧杆菌菌株在制备用于预防或治疗内毒素介导和/或相关疾病和人或宠物食物的组合物中的用途 其制备的组合物。
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公开(公告)号:US20100136662A1
公开(公告)日:2010-06-03
申请号:US12488293
申请日:2009-06-19
IPC分类号: C12N1/20
CPC分类号: A61K35/747 , A61K35/745 , Y10S435/853 , Y10S435/854
摘要: The invention relates to the use of at least one strain of lactic acid bacteria and/or bifidobacteria having hydrophobic surface properties, for the preparation of a composition intended for the prevention or the treatment of endotoxin mediated and/or associated disorders and human or pet food compositions prepared thereof
摘要翻译: 本发明涉及至少一种具有疏水表面性质的乳酸菌和/或双歧杆菌菌株在制备用于预防或治疗内毒素介导和/或相关疾病和人或宠物食物的组合物中的用途 其制备的组合物
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公开(公告)号:US20090011077A1
公开(公告)日:2009-01-08
申请号:US12097847
申请日:2007-01-04
申请人: Eduardo Schiffrin , Teresa Grad , Francois Murbach
发明人: Eduardo Schiffrin , Teresa Grad , Francois Murbach
CPC分类号: A23L33/40 , A23L33/175 , A61K9/0095 , A61K31/198
摘要: Methods and compositions for providing nutrition to critically ill patients are presented. In an embodiment, the method comprises administering to a patient undergoing a condition characterized bya systemic inflammatory response phase followed by a compensatory anti-inflammatory response phase a first nutritional composition while the patient is experiencing the first phase and administering to the patient a second different nutritional composition while the patient is experiencing the second phase.
摘要翻译: 介绍了向危重病人提供营养的方法和组成。 在一个实施方案中,所述方法包括在患者经历第一阶段并且向患者施用第二种不同营养物质的情况下,对患有经历系统性炎症反应阶段的特征的患者施用第一营养组合物,然后补偿性抗炎反应阶段的第一营养组合物 而患者正在经历第二阶段。
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