Process for preparing urethane compound for medical instruments
    1.
    发明授权
    Process for preparing urethane compound for medical instruments 有权
    制备医疗器械用聚氨酯化合物的方法

    公开(公告)号:US06770727B2

    公开(公告)日:2004-08-03

    申请号:US10284104

    申请日:2002-10-31

    IPC分类号: C08G1822

    摘要: A process for preparing an urethane compound for medical instruments, characterized by reacting a hydroxyl compound (A) with an isocyanate compound (B) in the absence of a catalyst or in the presence of a reaction catalyst other than an organic tin compound to give an urethane compound (I). According to the process, the urethane compound showing high safety can be easily prepared, in particular, while molecular weight of the compound is controlled.

    摘要翻译: 一种用于医疗器械的氨基甲酸酯化合物的制备方法,其特征在于在不存在催化剂的情况下或在除有机锡化合物以外的反应催化剂存在下使羟基化合物(A)与异氰酸酯化合物(B)反应,得到 氨基甲酸酯化合物(I)。 根据该方法,可以容易地制备显示高安全性的氨基甲酸酯化合物,特别是在控制化合物的分子量时。

    Ocular lens materials and process for producing the same
    2.
    发明授权
    Ocular lens materials and process for producing the same 有权
    眼镜材料及其制造方法

    公开(公告)号:US06727336B1

    公开(公告)日:2004-04-27

    申请号:US09926459

    申请日:2001-11-07

    IPC分类号: C08F23008

    摘要: An ocular lens material comprising a siloxane-containing polymer obtained by polymerizing a monomer mixture containing (A) a siloxane macromonomer having at least two active unsaturated groups and a number average molecular weight of 2,000 to 100,000; and (B) a vinyl ester of lower fatty acid as essential components. An ocular lens material comprising a polymer obtained by saponification of the siloxane-containing polymer. Processes for producing the ocular lens materials. The ocular lens materials are excellent not only in lipid-stain resistance, wettability and oxygen permeability, but also in flexibility, particularly, shape recovery at the same time.

    摘要翻译: 一种眼透镜材料,其包含通过聚合含有(A)具有至少两个活性不饱和基团和数均分子量为2,000至100,000的硅氧烷大分子单体的单体混合物而获得的含硅氧烷聚合物; 和(B)低级脂肪酸的乙烯基酯作为必需成分。 一种眼透镜材料,其包含通过使含硅氧烷的聚合物皂化获得的聚合物。 用于制造眼镜片材料的方法。 眼透镜材料不仅具有耐脂质耐污性,润湿性和透氧性,而且在柔韧性,特别是同时形状恢复方面都是优异的。

    Process for preparing ocular lens with urethane compound and process for preparing urethane compound for medical instruments
    5.
    发明授权
    Process for preparing ocular lens with urethane compound and process for preparing urethane compound for medical instruments 失效
    用氨基甲酸酯化合物制备眼镜片的方法和用于制备医疗器械的聚氨酯化合物的方法

    公开(公告)号:US06770728B2

    公开(公告)日:2004-08-03

    申请号:US10284112

    申请日:2002-10-31

    IPC分类号: C08G1822

    摘要: A process for preparing an ocular lens with a urethane compound comprising the steps of a) preparing a urethane compound by reacting at least one hydroxyl compound and at least one isocyanate compound in the presence of an organic iron compound, b) removing the organic iron compound from the urethane compound obtained in the step a) c) mixing the urethane compound obtained in the step b) with at least one compound selected from the group consisting of another copolymerizable compound, a crosslinking agent, a UV absorbent, a dye, a polymerization initiator, a photosensitizer, and an organic solvent to obtain a mixture, and d) curing the mixture obtained in the step c) to prepare a lens.

    摘要翻译: 一种制备具有氨基甲酸酯化合物的眼用透镜的方法,包括以下步骤:a)在有机铁化合物存在下使至少一种羟基化合物和至少一种异氰酸酯化合物反应制备氨基甲酸酯化合物,b)从有机铁化合物中除去有机铁化合物 在步骤a)中获得的氨基甲酸酯化合物c)将步骤b)中获得的氨基甲酸酯化合物与至少一种选自另一种可共聚化合物,交联剂,UV吸收剂,染料,聚合引发剂 ,光敏剂和有机溶剂以获得混合物,并且d)固化步骤c)中获得的混合物以制备透镜。

    Ocular lens material and process for producing the same
    6.
    发明授权
    Ocular lens material and process for producing the same 失效
    眼镜片材料及其制造方法

    公开(公告)号:US06255362B1

    公开(公告)日:2001-07-03

    申请号:US09248264

    申请日:1999-02-11

    申请人: Eri Ito

    发明人: Eri Ito

    IPC分类号: B29D1100

    CPC分类号: G02B1/043 C08L51/085

    摘要: An ocular lens material comprising a polymer prepared by polymerizing a polymerizable component for an ocular lens, containing (A) 20 to 50% by weight of a silicon-containing alkyl acrylate, (B) 20 to 50% by weight of a polysiloxane macromonomer in which a polymerizable group bonds to a siloxane main chain through at least one urethane bond, (C) 10 to 50% by weight of at least one of hydroxyalkyl acrylates and at least one of hydroxyalkyl methacrylates, and (D) 0.01 to 10% by weight of a crosslinkable compound having at least two polymerizable groups, and a process for producing the same. The ocular lens material shows excellent stain resistance and excellent flexibility at the same time in addition to excellent transparency, and can be easily produced by the process.

    摘要翻译: 一种眼透镜材料,其包含通过聚合用于眼透镜的可聚合组分制备的聚合物,其包含(A)20至50重量%的含硅烷基丙烯酸酯,(B)20至50重量%的聚硅氧烷大分子单体 其中可聚合基团通过至少一个氨基甲酸酯键与硅氧烷主链键合,(C)10至50重量%的至少一种丙烯酸羟烷基酯和至少一种甲基丙烯酸羟烷基酯,和(D)0.01至10% 具有至少两个可聚合基团的交联化合物的重量及其制备方法。 眼透镜材料除了具有优异的透明性之外,同时显示优异的耐污染性和优异的柔韧性,并且可以容易地通过该方法产生。

    Process for producing ocular lens and ocular lens produced by the process
    9.
    发明授权
    Process for producing ocular lens and ocular lens produced by the process 失效
    用于制造由该方法生产的眼透镜和眼透镜的方法

    公开(公告)号:US5855825A

    公开(公告)日:1999-01-05

    申请号:US836017

    申请日:1997-04-29

    申请人: Eri Ito

    发明人: Eri Ito

    IPC分类号: C08F2/00 G02B1/04 B29D11/00

    CPC分类号: G02B1/043

    摘要: A process for producing an ocular lens characterized by mixing a polymerizable component for an ocular lens with an organic solvent (I) capable of dissolving the polymerizable component, injecting the obtained mixture into a mold having the desired shape for an ocular lens and then, preparing a polymer by the polymerization reaction, immersing the polymer taken off from the mold in an aqueous organic solvent (II) having compatibility with the organic solvent (I), and then, hydrating the polymer, and an ocular lens produced by the process, which is, in particular, remarkably excellent in transparency.

    摘要翻译: PCT No.PCT / JP96 / 02520 Sec。 371日期1997年04月29日 102(e)1997年4月29日PCT PCT 1996年9月4日PCT公布。 公开号WO97 / 09169 日期1997年3月13日制造眼透镜的方法,其特征在于将眼用透镜用聚合性组分与能够溶解可聚合组分的有机溶剂(I)混合,将所得混合物注入具有所需形状的模具中用于眼睛 透镜,然后通过聚合反应制备聚合物,将从模具中取出的聚合物浸渍在与有机溶剂(I)相容的水性有机溶剂(II)中,然后水合聚合物和产生的眼透镜 特别是透明度优异的过程。