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公开(公告)号：US20230393028A1
公开(公告)日：2023-12-07
申请号：US18032095
申请日：2021-11-12
申请人： Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e. V. , Universitaet des Saarlandes
发明人： Heiko ZIMMERMANN
CPC分类号： G01N1/04 , B01L3/54 , H04L63/0853 , B01L2300/023
摘要： A sample collection kit for collecting plant samples, in particular algae samples for biomedical applications, comprises at least one sample container adapted to receive plant samples, a sensor arrangement having multiple sensors that can be used to capture sample data, a data recording device adapted to record the sample data, a tool arrangement having collection tools, which are adapted for harvesting the plant samples, and having processing tools, which are adapted for processing the plant samples, a container device adapted to receive the tool arrangement and the de-vice arrangement in a state that is isolated from the surroundings, and identification markings that include identification data and are attached to the at least one sample container, the collection tools and the processing tools, wherein there is provision for an authentication device that contains an electronically readable data carrier containing authentication data that represent a state of the sample collection kit, and the authentication device is attached to at least one from the container device, the at least one sample container, the collection tools and the processing tools. An authentication arrangement and a method for testing a state of a sample collection kit are also described.
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公开(公告)号：US20230164963A1
公开(公告)日：2023-05-25
申请号：US18058277
申请日：2022-11-23
申请人： Dr. Ing. h.c. F. Porsche Aktiengesellschaft , Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e. V
发明人： Maximilian BARKOW , Patrick FUCHS , Timijan VELIC , Bernd ECKARDT , Maximilian HOFMANN , Hubert RAUH , Andre MUELLER , Benjamin BAYER , Jordan SORGE
CPC分类号： H05K7/20927 , H05K1/0209
摘要： A liquid-cooled power electronics unit includes a planar circuit board body having conductor tracks, a wet side with a wet space for carrying a dielectric cooling liquid, and a fluidically, separated dry side, wherein at least two high-voltage power semiconductors are arranged on the circuit board body on the wet side within the wet space, the high-voltage power semiconductors being cooled by the cooling liquid, and an electronic low-voltage circuit is arranged on the dry side of the circuit board body.
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公开(公告)号：US11366026B2
公开(公告)日：2022-06-21
申请号：US16097255
申请日：2017-03-31
发明人： Guenter R. Fuhr , Heiko Zimmermann
摘要： The invention relates to a method for monitoring the temperature of a cryopreserved biological sample. The invention also relates to a device for monitoring the temperature of a cryopreserved biological sample. The device (10) for monitoring the temperature of a cryopreserved biological sample comprises a sample container (1) having a receiving space (2) for receiving a biological sample (6). The device also comprises at least one chamber (11) having an interior that is not fluidically connected to the receiving space (2) and is only partially filled with an indicator substance (7) with a melting temperature in a region of −20° C. to −140° C. The chamber (11) has a barrier (13) that causes the indicator substance (7) to move into a second sub-region (12b) of the chamber (11) when the indicator substance (7) in a first sub-region (12a) of the chamber is in the fluid aggregate state.
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4.发明授权公开(公告)号：US10967378B2
公开(公告)日：2021-04-06
申请号：US16310438
申请日：2017-06-01
发明人： Heiko Zimmermann
摘要： The invention relates to a sample collection kit (100) for collecting plant samples, in particular algae samples for biomedical applications, which sample collection kit comprises at least one sample container for holding plant samples, a plurality of sensors, by means of which sample data can be captured, a data-recording apparatus for recording the sample data, an arrangement of tools, which has collection tools designed for harvesting the plant samples and processing tools designed for processing the plant samples, an arrangement of devices, which has auxiliary devices that can be used in the collection, transport, and processing of the plant samples, a container apparatus (70), which is designed to hold the arrangement of tools and the arrangement of devices in isolation from the environment, and identification markings (80), which contain identification data and are applied to the at least one sample container (70) to the collection tools, and to the processing tools. The invention further relates to a sample collection method.
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5.发明申请公开(公告)号：US20200236079A1
公开(公告)日：2020-07-23
申请号：US16251132
申请日：2019-01-18
发明人： Haya SHULMAN , Kevin FREEMAN , Markus SCHNEIDER
摘要： Examples relate to a method, an apparatus and a computer program for processing a plurality of electronic messages, and to an electronic message server. The method comprises obtaining (110) the plurality of electronic messages. The method further comprises selecting (120) at least a subset of electronic messages of the plurality of electronic messages based on information related to a plurality of suspicious electronic message sender identifiers. The method further comprises determining (130), whether a number of electronic messages of the subset of electronic messages obtained within a pre-defined time interval exceeds a threshold. The method further comprises discarding (140) the electronic messages of the subset of electronic messages if the number of electronic messages of the subset of electronic messages obtained within the pre-defined time interval exceeds the threshold.
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公开(公告)号：US20190133111A1
公开(公告)日：2019-05-09
申请号：US16095936
申请日：2017-03-31
发明人： Guenter R. FUHR , Heiko ZIMMERMANN
摘要： The invention relates to a device for monitoring the temperature of a cryopreserved biological sample, comprising a sample container (1) having a receiving space (2) for receiving a biological sample (6) and a cover (3) for closing the receiving space. The device also comprises a chamber arranged inside the sample container, in particular in the receiving space and/or in the cover, the interior (12; 22; 32; 42) of which is not fluidically connected to the receiving space (2) and is only partially filled with at least one indicator substance (7) having a melting temperature in the region between −20° C. and −140 ° C. The invention also relates to a method for monitoring the temperature of cryopreserved samples, comprising the following steps: providing a device (10; 20; 30; 40) for 12b temperature monitoring; freezing the indicator sub stance/s, wherein the at least one chamber can be placed in a first position during the freezing of the indicator substance/s and in a second position after the freezing and when a temperature of the indicator substance/s is below the melting temperature, in which position a melting of the indicator substance/s leads to an at least partial shift and/or change in shape of the chamber filling, with the influence of the force of gravity.
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公开(公告)号：US20190091634A1
公开(公告)日：2019-03-28
申请号：US16136409
申请日：2018-09-20
摘要： Disclosed is a method for producing a palladium-based permeation membrane which is suitable for the separation of hydrogen from gas-gas or liquid-gas mixtures. The permeation membrane is produced by applying a palladium complex, dissolved in a solvent, to a nanoporous support system having pores in a size range of from 0.5 nm to 50 nm, removing the solvent by drying, removing of organic constituents of the palladium complex by a heat treatment, and carrying out a final heat treatment under reducing conditions at a temperature ranging from about 300° C. to about 900° C.
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公开(公告)号：US09951366B2
公开(公告)日：2018-04-24
申请号：US15024125
申请日：2014-09-17
CPC分类号： C12P21/00 , C07K5/0808 , C07K5/1016 , C07K5/1021 , C12M23/34 , C12M29/04 , C12P21/02
摘要： The invention relates to an improved cell-free protein synthesis method using a eukaryotic cell lysate in the presence of a caspase inhibitor, to a device for carrying out said method, and to the use of a caspase inhibitor for increasing the protein yield or for increasing the stability of the synthesized proteins in such a cell-free protein synthesis method using a eukaryotic cell lysate. In a preferred embodiment of the invention, the cell-free protein synthesis method is carried out as a continuous method in a device which comprises at least two compartments separated by a dialysis membrane. The translation reaction takes place in at least one first compartment, the reaction compartment, and during the translation reaction i) reactants are diffused from at least one other compartment, the supply and discharge compartment, into the reaction compartment, and ii) reaction byproducts are diffused from the reaction compartment into the supply and discharge compartment by means of the dialysis membrane. According to the invention, the caspase inhibitor is provided at least in the reaction compartment but can also be preferably provided in the supply and discharge compartment in order to supply unused inhibitors to the reaction compartment.
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9.发明授权Hard-material-coated bodies composed of metal, cemented hard material, cermet or ceramic and processes for producing such bodies 有权由金属，硬质合金材料，金属陶瓷或陶瓷构成的硬质材料涂层体以及用于制造这种体的方法公开(公告)号：US09309593B2
公开(公告)日：2016-04-12
申请号：US14360724
申请日：2012-11-28
发明人： Ingolf Endler , Sebastian Scholz
IPC分类号： C23C16/36 , C23C16/34 , C04B41/87 , C04B41/00 , C04B41/50 , C23C28/04 , C04B41/45 , C04B41/85 , C23C16/448 , C04B111/00
CPC分类号： C23C16/34 , C04B41/009 , C04B41/4531 , C04B41/5062 , C04B41/5068 , C04B41/85 , C04B41/87 , C04B2111/00405 , C23C16/36 , C23C16/448 , C23C28/04 , C04B35/00 , C04B41/4549 , C04B41/5001 , C04B41/5059 , C04B41/5061 , C04B41/5066 , C04B41/52
摘要： Hard-material-coated bodies composed of metal, cemented hard material, cermet or ceramic, coated with a TiSiCN composite layer or with a multilayer layer system which contains at least one TiSiCN composite layer. The TiSiCN composite layer is a nanocomposite layer which has been produced by a thermal CVD process without additional plasma excitation and contains a nanocrystalline phase composed of TiCxN1-x having a crystallite size in the range from 5 nm to 150 nm and a second phase composed of amorphous SiCxNy. The layer is characterized by a high hardness, a high oxidation and heat resistance and a high adhesive strength.
摘要翻译： 由金属，硬质合金材料，金属陶瓷或陶瓷组成的涂覆有TiSiCN复合层或包含至少一个TiSiCN复合层的多层系统的硬质材料涂层体。 TiSiCN复合层是一种纳米复合层，其通过热CVD工艺生产而不需要另外的等离子体激发，并且包含由5nm至150nm范围内的微晶尺寸的TiCxN1-x组成的纳晶晶相，第二相由 无定形SiCxNy。 该层的特征在于高硬度，高氧化和耐热性和高粘合强度。
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10.发明申请METHOD, DEVICE AND PORTABLE METER FOR DETECTING DEGRADATION PRODUCTS OF BIOLOGICAL MOLECULES IN LAYERS OF A LAYER SYSTEM 审中-公开用于检测层系统层中生物分子降解产物的方法，装置和便携式仪器公开(公告)号：US20150192521A1
公开(公告)日：2015-07-09
申请号：US14409116
申请日：2013-06-18
CPC分类号： G01N21/6486 , G01N21/94 , G01N33/521 , G01N33/57438 , G01N2201/06113
摘要： The invention is directed to a method for the detection of degradation products of biological molecules in layers of a layer system (1) in which the degradation products are acted upon by an excitation radiation (3) and a radiation (6) of the degradation products which is induced by the excitation radiation (3) is detected and a concentration of degradation products is determined based on a comparison of the measurement values of the radiation (6) with reference data, characterized in that there is provided a layer system (1) which includes a through layer (1.1) which is transparent to the excitation radiation (3) and radiation (6) and at least one further receiver layer containing degradation products, and in that the excitation radiation (3) is directed into the receiver layer through the through layer (1.1). The invention is further directed to an apparatus and a portable measuring device (11) for detecting the degradation products.
摘要翻译： 本发明涉及一种用于检测层系统（1）的层中的生物分子的降解产物的方法，其中降解产物通过激发辐射（3）和降解产物的辐射（6）作用 根据辐射（6）的测量值与参考数据的比较，检测由激发辐射（3）感应的降解产物的浓度，其特征在于，提供层系统（1） 其包括对激发辐射（3）和辐射（6）是透明的通透层（1.1）以及包含降解产物的至少一个另外的接收层，并且激发辐射（3）通过 贯穿层（1.1）。 本发明还涉及一种用于检测劣化产物的装置和便携式测量装置（11）。
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