Use of intramolecularly, covalently cross-linked proteins as binding partners in immunoassays
    3.
    发明授权
    Use of intramolecularly, covalently cross-linked proteins as binding partners in immunoassays 有权
    在免疫测定中使用分子内,共价交联的蛋白质作为结合配偶体

    公开(公告)号:US07351799B2

    公开(公告)日:2008-04-01

    申请号:US10447129

    申请日:2003-05-28

    IPC分类号: C07K14/00

    摘要: The invention concerns the use of intramolecularly, covalently cross-linked proteins and covalently cross-linked reverse transcriptase from HIV as immunological binding partners in immunoassays. It also concerns immunological test procedures for detecting an analyte in a sample in which intramolecularly, covalently cross-linked proteins are used as binding partners, and it further concerns intramolecularly, covalently cross-linked reverse transcriptase from HIV and a method for producing this reverse transcriptase.

    摘要翻译: 本发明涉及在免疫测定中使用分子内,共价交联的蛋白质和来自HIV的共价交联的逆转录酶作为免疫结合配偶体。 它还涉及用于检测分子内,共价交联的蛋白质用作结合伴侣的样品中的分析物的免疫测试程序,并且还涉及从HIV分子内,共价交联的逆转录酶以及产生该逆转录酶的方法 。

    METHOD FOR DETECTION OF SPECIFIC IMMUNOGLOBULIN CLASS G ANTIBODIES
    6.
    发明申请
    METHOD FOR DETECTION OF SPECIFIC IMMUNOGLOBULIN CLASS G ANTIBODIES 有权
    检测特异性免疫球蛋白G类抗体的方法

    公开(公告)号:US20110143454A1

    公开(公告)日:2011-06-16

    申请号:US12817469

    申请日:2010-06-17

    IPC分类号: G01N33/543 G01N33/566

    摘要: The invention relates to a method for determining an analyte in a sample by means of an assay that can be carried out in a one-step format without performing washing steps. The method includes a first analyte-specific receptor that contains at least one bonding point for the analyte, e.g., several antibodies on a particle, as well as a second analyte-specific receptor that can selectively bond to an arrangement comprising at least two analyte molecules which are bound to the first receptor. An antibody sandwich immune assay is described in which the detection is based on electrochemiluminescence.

    摘要翻译: 本发明涉及通过可以以一步格式执行的测定法来测定样品中分析物的方法,而不进行洗涤步骤。 该方法包括第一分析物特异性受体,其包含分析物的至少一个结合点,例如颗粒上的几种抗体,以及可选择性地结合至包含至少两种分析物分子的装置的第二分析物特异性受体 它们与第一受体结合。 描述了抗体夹心免疫测定法,其中检测基于电化学发光。

    Use of Intramolecularly, Covalently Cross-Linked Proteins As Binding Partners In Immunoassays
    7.
    发明申请
    Use of Intramolecularly, Covalently Cross-Linked Proteins As Binding Partners In Immunoassays 审中-公开
    使用分子内,共价交联蛋白作为结合伙伴在免疫测定

    公开(公告)号:US20090220987A1

    公开(公告)日:2009-09-03

    申请号:US12464376

    申请日:2009-05-12

    IPC分类号: G01N33/53

    摘要: The invention concerns the use of intramolecularly, covalently cross-linked proteins and covalently cross-linked reverse transcriptase from HIV as immunological binding partners in immunoassays. It also concerns immunological test procedures for detecting an analyte in a sample in which intramolecularly, covalently cross-linked proteins are used as binding partners, and it further concerns intramolecularly, covalently cross-linked reverse transcriptase from HIV and a method for producing this reverse transcriptase.

    摘要翻译: 本发明涉及在免疫测定中使用分子内,共价交联的蛋白质和来自HIV的共价交联的逆转录酶作为免疫结合配偶体。 它还涉及用于检测分子内,共价交联的蛋白质用作结合伴侣的样品中的分析物的免疫测试程序,并且还涉及从HIV分子内,共价交联的逆转录酶以及产生该逆转录酶的方法 。

    Use of intramolecularly, covalently cross-linked proteins as binding partners in immunoassays
    10.
    发明授权
    Use of intramolecularly, covalently cross-linked proteins as binding partners in immunoassays 有权
    在免疫测定中使用分子内,共价交联的蛋白质作为结合配偶体

    公开(公告)号:US07547533B2

    公开(公告)日:2009-06-16

    申请号:US11968806

    申请日:2008-01-03

    IPC分类号: C12N9/00

    摘要: The invention concerns the use of intramolecularly, covalently cross-linked proteins and covalently cross-linked reverse transcriptase from HIV as immunological binding partners in immunoassays. It also concerns immunological test procedures for detecting an analyte in a sample in which intramolecularly, covalently cross-linked proteins are used as binding partners, and it further concerns intramolecularly, covalently cross-linked reverse transcriptase from HIV and a method for producing this reverse transcriptase.

    摘要翻译: 本发明涉及在免疫测定中使用分子内,共价交联的蛋白质和来自HIV的共价交联的逆转录酶作为免疫结合配偶体。 它还涉及用于检测分子内,共价交联的蛋白质用作结合伴侣的样品中的分析物的免疫测试程序,并且还涉及从HIV分子内,共价交联的逆转录酶以及产生该逆转录酶的方法 。