Abstract:
A method of processing skin surface observation measuring data able to address various sicknesses and reduce an error in sickness detection, and a measuring apparatus requiring no filter with a simple structure. The measuring apparatus comprises a means of applying a white light to a biological surface as a sample, a means of detecting the spectra of the white light reflected off a plurality of positions on the biological surface, a means of plotting the absorbances of the above spectra to a light spectrum multi-dimensional space, a means of subjecting data in the spectrum multi-dimension space obtained from the plurality of positions to multivariate analysis to determine the eigenvectors of at least first, second and third principal components, and a means of projecting data at respective positions in respective eigenvector directions to display their magnitudes on a two-dimension display screen on a gray scale or in colors corresponding to the magnitudes; and a measuring method by the apparatus.
Abstract:
An ultrasonic distance sensor generates ultrasonic waves and transmit same toward a target surface, the distance to which is to be measured, through a predetermined path. The sensor is also provided with a reference surface which reflects ultrasonic waves, which reference surface is disposed within the aforementioned predetermined path of the ultrasonic waves. A receiver associated with delayed pulse generators receives the ultrasonic waves reflected by the reference surface or by the target surface, selectively. Arithmetic operations based on the elapsed time between transmission of the ultrasonic waves and reception of the ultrasonic waves from the reference surface derive the transmission velocity of the ultrasonic wave based on the known distance to the reference surface. On the basis of the derived transmission velocity and the elapsed time measured with respect to the ultrasonic waves reflected by the target surface, the distance to the target surface is derived. The aforementioned ultrasonic sensor is used to monitor the external shape of an object. In order to monitor the external shape of the object, a system is composed of a plurality of the ultrasonic sensors. The sensors comprises a primary sensor or sensors directed toward the external surface of the object and an auxiliary sensor or sensors directed to a reference line.
Abstract:
The present invention provides screening methods for GPCRs based on the discovery that the affinity of a receptor agonist for a GPCR (such as the parathyroid hormone receptor) when not bound to a G-protein is correlated with the length of time over which the agonist is effective, independently of its pharmacokinetic properties. The invention also provides PTH- and PTHrP-derived polypeptides.
Abstract:
A method of processing skin surface observation measuring data which is able to address various sicknesses and reduce an error in sickness detection, and a measuring apparatus requiring no filter. The measuring apparatus an irradiator applying a white light to a biological surface as a sample, a detector detecting the spectra of the white light reflected off a plurality of positions on the biological surface, a plotter plotting the absorbances of the above spectra to a light spectrum multi-dimensional space, an analyzer subjecting data in the spectrum multi-dimension space obtained from the plurality of positions to multivariate analysis to determine the eigenvectors of at least first, second and third principal components, and a display projecting data at respective positions in respective eigenvector directions to display their magnitudes on a two-dimension display screen on a gray scale or in colors corresponding to the magnitudes; and a measuring method by the apparatus.
Abstract:
A transmission testing device that performs tests to verify transmission functionality has: an output shaft directly or indirectly coupled to a differential gear section of the transmission; a rotary driving unit for rotating the output shaft; and a cylindrical meshing unit comprising a meshing portion to mesh with a side gear of the differential gear section, and a chuck portion in which a fluid circuit is formed. The meshing unit is fixed to a differential case of the differential gear section by way of expanding the chuck portion in the radial direction of the chuck portion by applying pressure to the fluid in the fluid circuit.
Abstract:
In measuring a distribution of crystal grains in metal sheet, an exciting frequency of ultrasonic wave is determined such that a wavelength of the ultrasonic wave propagated in a direction of the sheet thickness of the grains each having an aimed orientation is set at a value of twice the thickness of the sheet multiplied by about integers or about half integers, burst-like ultrasonic pulses having this frequency and including two or more waves are directed into the direction of the sheet thickness by use of an ultrasonic probe moving relatively with a body to be measured, multiple reflected waves generated from the bottom and top faces of the metal sheet upon the reflection from the sheet surface are caused to interfere with each other, the multiple reflected waves, which have interfered with each other, are detected, orientation of the grains in the metal sheet are estimated from the magnitudes in amplitude of the interferent multiple reflected waves thus detected, and the distribution of the grains in orientation in various portions, into which the ultrasonic wave is directed, is detected two-dimensionally.
Abstract:
A transmission testing device that performs tests to verify transmission functionality has: an output shaft directly or indirectly coupled to a differential gear section of the transmission; a rotary driving unit for rotating the output shaft; and a cylindrical meshing unit comprising a meshing portion to mesh with a side gear of the differential gear section, and a chuck portion in which a fluid circuit is formed. The meshing unit is fixed to a differential case of the differential gear section by way of expanding the chuck portion in the radial direction of the chuck portion by applying pressure to the fluid in the fluid circuit.
Abstract:
The present invention provides screening methods for GPCRs based on the discovery that the affinity of a receptor agonist for a GPCR (such as the parathyroid hormone receptor) when not bound to a G-protein is correlated with the length of time over which the agonist is effective, independently of its pharmacokinetic properties. The invention also provides PTH- and PTHrP-derived polypeptides.