OPTICAL STIMULATION OF PHOTOSENSITIZED CELLS
    3.
    发明申请
    OPTICAL STIMULATION OF PHOTOSENSITIZED CELLS 审中-公开
    光敏细胞的光学刺激

    公开(公告)号:US20110127405A1

    公开(公告)日:2011-06-02

    申请号:US12992963

    申请日:2009-05-18

    Abstract: This invention describes a device for optical stimulation of cells and other biological structures. It has an ability to target multiple cells and/or multiple sub-cellular targets. The stimulation optical pattern on each cell can be independently controlled with individual frequencies. The light sensitivity of the cells can be imparted as a result of genetic expression of surface and/or subsurface proteins, chemical modification of existing proteins, or via the release of caged entities which in turn act to stimulate the cell through chemical means. The embodiment is capable of functioning on neurons but can also be used for other cells. It can perform optimal stimulation with sub-cellular resolutions, record the activity of the targeted cells and perform processing to ensure calibration.

    Abstract translation: 本发明描述了用于光学刺激细胞和其他生物结构的装置。 它具有靶向多个细胞和/或多个亚细胞靶标的能力。 每个单元上的刺激光学图案可以独立地用各个频率控制。 由于表面和/或地下蛋白质的遗传表达,现有蛋白质的化学修饰,或通过释放的笼状实体,细胞的光敏感性可以赋予细胞,这些实体又通过化学方式刺激细胞。 该实施例能够在神经元上起作用,但也可用于其他细胞。 它可以用亚细胞分辨率执行最佳刺激,记录目标细胞的活性,并进行处理以确保校准。

    Molten Metal Pressure Pour Furnace
    4.
    发明申请
    Molten Metal Pressure Pour Furnace 失效
    熔融金属压力炉

    公开(公告)号:US20080011787A1

    公开(公告)日:2008-01-17

    申请号:US11862735

    申请日:2007-09-27

    CPC classification number: B22D18/04

    Abstract: An apparatus and process are provided for discharging a dose of a molten metal from a pressure pour furnace. A heating chamber of the furnace is used to keep the molten metal at a selected temperature. A sealing port between the heating chamber and a pressure chamber allows selectively filling of the pressure chamber with molten metal from the heating chamber by inserting or removing a sealing means from the sealing port. The sealing means inserted in the sealing port also provides a means for preventing back flow of the molten metal to the heating chamber when the pressure chamber is pressurized. Differential pressure sensing of the pressure of the molten metal in the pressure chamber and the pressure of the pressurizing gas in the pressure chamber can optionally be used to achieve an accurate measured discharge from the pressure chamber as the level of molten metal decreases from repeated discharges of doses from the furnace. The sealing plate in which the sealing port is disposed and the sealing means selectively inserted or removed from the sealing port can be used as a metering valve between two molten metal containing components such as a launder and a pressure chamber of a pressure pour furnace.

    Abstract translation: 提供了用于从压力倒出炉排出一定量的熔融金属的装置和方法。 使用炉的加热室将熔融金属保持在选定的温度。 加热室和压力室之间的密封端口允许通过从密封口插入或移除密封装置从加热室选择性地填充熔融金属的压力室。 插入密封口中的密封装置还提供了当压力室被加压时防止熔融金属向加热室的回流的装置。 压力室中的熔融金属的压力的差压检测和压力室中的加压气体的压力可以可选地用于实现来自压力室的精确测量的排放,因为熔融金属的水平由于重复的排放 来自炉子的剂量 其中密封口设置的密封板和从密封口选择性地插入或取出的密封装置可以用作两个含熔融金属的组件如压滤池和压力浇注炉的压力室之间的计量阀。

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