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公开(公告)号：US09062209B2
公开(公告)日：2015-06-23
申请号：US12904711
申请日：2010-10-14
Applicant: Chang Xu , Hai Hui Lin , Parfait Jean Marie Likibi
Inventor： Chang Xu , Hai Hui Lin , Parfait Jean Marie Likibi
IPC: C09D11/10 , C08F8/00 , C09C3/10 , C09C1/62 , C09C1/64 , C09C3/12 , C09D7/12 , C09D5/02 , C08K3/08 , C08K3/22 , C08K9/08
CPC classification number: C09C3/10 , C08K3/08 , C08K3/22 , C08K9/08 , C09C1/62 , C09C1/644 , C09C1/648 , C09C3/12 , C09D5/028 , C09D7/62
Abstract: A coated platelet that includes a robust polymer coating that has substantially uniform structures, a method for producing the coated platelet and a system that includes the coated platelet are described. The disclosed method involves immobilizing initiator molecules onto the surfaces of the platelet by using surface coupling groups and polymerization from initiating sites of the initiator anchored on the surface of the platelet. The disclosed method allows uniform growth of the polymer chains so as to produce robust coated platelets with a smooth coated surface. The disclosed system includes only the disclosed coated platelet and a solvent and eliminates the need to add polymer resins separate from the resins that are covalently attached to the platelet.
Abstract translation: 描述了包括具有基本均匀结构的坚固的聚合物涂层的涂覆血小板，制备涂覆的血小板的方法和包括涂覆的血小板的系统。 所公开的方法包括通过使用表面偶联基团将引发剂分子固定到血小板的表面上，并将聚合从引发剂的起始位点锚定在血小板的表面上。 所公开的方法允许聚合物链的均匀生长，以便制备具有光滑涂布表面的坚固的涂覆的血小板。 所公开的系统仅包括所公开的涂覆的血小板和溶剂，并且不需要添加与共价连接到血小板上的树脂分开的聚合物树脂。
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公开(公告)号：US08211224B2
公开(公告)日：2012-07-03
申请号：US11931473
申请日：2007-10-31
Applicant: Aaron M. Hollman , Stephane Nicolas , Philippe Schottland , Marguerite Debacker , Aurelie Antonowicz , Hai Hui Lin
Inventor： Aaron M. Hollman , Stephane Nicolas , Philippe Schottland , Marguerite Debacker , Aurelie Antonowicz , Hai Hui Lin
CPC classification number: C09C1/0015 , C01P2006/62 , C01P2006/63 , C01P2006/64 , C01P2006/65 , C01P2006/66 , C09C1/0021 , C09C2200/1004 , C09C2200/102 , C09C2200/1087 , C09C2200/301 , C09C2200/302 , C09C2200/304 , C09C2200/306 , C09C2200/407 , C09D5/36
Abstract: A pearlescent pigment comprising a substrate and a first layer, wherein the first layer comprises iron oxide, wherein the iron has from about 1% to about 30% Fe(II) and from about 70% to about 99% Fe(III). A process for making these pearlescent pigment, comprise reducing a metal oxide substrate with a hydrogen source in the presence of a noble metal catalyst in a liquid medium. The pigments may be used in a variety of applications including cosmetics, plastics, automotive, or architectural coatings.
Abstract translation: 一种珠光颜料，其包含基材和第一层，其中所述第一层包含氧化铁，其中所述铁具有约1％至约30％的Fe（II）和约70％至约99％的Fe（III）。 制备这些珠光颜料的方法包括在液体介质中在贵金属催化剂存在下用氢源还原金属氧化物基底。 颜料可用于各种应用，包括化妆品，塑料，汽车或建筑涂料。
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公开(公告)号：US20110130510A1
公开(公告)日：2011-06-02
申请号：US12904711
申请日：2010-10-14
Applicant: Chang XU , Hai Hui LIN , Parfait Jean Marie LIKIBI
Inventor： Chang XU , Hai Hui LIN , Parfait Jean Marie LIKIBI
CPC classification number: C09C3/10 , C08K3/08 , C08K3/22 , C08K9/08 , C09C1/62 , C09C1/644 , C09C1/648 , C09C3/12 , C09D5/028 , C09D7/62
Abstract: A coated platelet that includes a robust polymer coating that has substantially uniform structures, a method for producing the coated platelet and a system that includes the coated platelet are described. The disclosed method involves immobilizing initiator molecules onto the surfaces of the platelet by using surface coupling groups and polymerization from initiating sites of the initiator anchored on the surface of the platelet. The disclosed method allows uniform growth of the polymer chains so as to produce robust coated platelets with a smooth coated surface. The disclosed system includes only the disclosed coated platelet and a solvent and eliminates the need to add polymer resins separate from the resins that are covalently attached to the platelet.
Abstract translation: 描述了包括具有基本均匀结构的坚固的聚合物涂层的涂覆血小板，制备涂覆的血小板的方法和包括涂覆的血小板的系统。 所公开的方法包括通过使用表面偶联基团将引发剂分子固定到血小板的表面上，并将聚合从引发剂的起始位点锚定在血小板的表面上。 所公开的方法允许聚合物链的均匀生长，以便制备具有光滑涂布表面的坚固的涂覆的血小板。 所公开的系统仅包括所公开的涂覆的血小板和溶剂，并且不需要添加与共价连接到血小板上的树脂分开的聚合物树脂。
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公开(公告)号：US20070110784A1
公开(公告)日：2007-05-17
申请号：US10555455
申请日：2004-05-03
Applicant: Yu-Ling Cheng , Michael May , John Semple , Hai-Hui Lin
Inventor： Yu-Ling Cheng , Michael May , John Semple , Hai-Hui Lin
CPC classification number: A61F2/0059
Abstract: The invention relates to the use of a thermal reversible gel, such as a copolymer composition, as a biological filler or implant. The gel has a semi-solid form at body temperature, but upon cooling to a temperature below a threshold level, the gel is liquefied and can be re-shaped, re-sized, manipulated or removed from the body. The gel may be used as a subcutaneous implant, a biological filler, joint or tissue spacer, for wrinkle filling or other cosmetic implants, as a soft-tissue replacement for reconstructive surgery, or as a barrier within the lumen of a biological structure, such as a blood vessel. The implant may be used to provide reversible birth control by providing, for example, a reversible barrier to the cervix or a reversible blockage of the lumen of the vas deferens.
Abstract translation: 本发明涉及热可逆凝胶如共聚物组合物作为生物填料或植入物的用途。 凝胶在体温下具有半固体形式，但是当冷却到低于阈值水平时，凝胶被液化，并且可以重新成形，重新调整尺寸，操作或从身体去除。 凝胶可以用作皮肤植入物，生物填充剂，关节或组织间隔物，用于皱纹填充或其它化妆品植入物，作为用于重建手术的软组织替代物，或作为生物结构内腔内的屏障，例如 作为血管。 植入物可用于通过提供例如子宫颈的可逆屏障或输精管腔的可逆阻塞来提供可逆的节育。
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公开(公告)号：US08486189B2
公开(公告)日：2013-07-16
申请号：US13524052
申请日：2012-06-15
Applicant: Aaron M. Hollman , Stephane Nicolas , Philippe Schottland , Marguerite Debacker , Aurelie Antonowicz , Hai Hui Lin
Inventor： Aaron M. Hollman , Stephane Nicolas , Philippe Schottland , Marguerite Debacker , Aurelie Antonowicz , Hai Hui Lin
CPC classification number: C09C1/0015 , A61K8/0258 , A61K8/19 , A61K2800/412 , A61K2800/436 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/10 , A61Q1/12 , A61Q3/02 , A61Q5/02 , A61Q19/00 , A61Q19/10 , C01P2006/62 , C01P2006/63 , C01P2006/64 , C01P2006/65 , C01P2006/66 , C09C1/0021 , C09C2200/1004 , C09C2200/102 , C09C2200/1087 , C09C2200/301 , C09C2200/302 , C09C2200/304 , C09C2200/306 , C09C2200/407 , C09D5/36
Abstract: A cosmetic containing a pearlescent pigment comprising a substrate and a first layer, wherein the first layer comprises iron oxide, wherein the iron has from about 1% to about 30% Fe(II) and from about 70% to about 99% Fe(III).
Abstract translation: 一种含有珠光颜料的化妆品，其包含基材和第一层，其中所述第一层包含氧化铁，其中所述铁具有约1％至约30％的Fe（II）和约70％至约99％的Fe（III ）。
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Patent Agency Ranking
公开(公告)号：US08349067B2
公开(公告)日：2013-01-08
申请号：US11931534
申请日：2007-10-31
Applicant: Aaron M. Hollman , Stephane Nicolas , Philippe Schottland , Marguerite Debacker , Aurelie Antonowicz , Hai Hui Lin
Inventor： Aaron M. Hollman , Stephane Nicolas , Philippe Schottland , Marguerite Debacker , Aurelie Antonowicz , Hai Hui Lin
CPC classification number: C09C1/0015 , C01P2006/62 , C01P2006/63 , C01P2006/64 , C01P2006/65 , C01P2006/66 , C09C1/0021 , C09C2200/1004 , C09C2200/102 , C09C2200/1087 , C09C2200/301 , C09C2200/302 , C09C2200/304 , C09C2200/306 , C09C2200/407 , C09D5/36
Abstract: A pearlescent pigment, wherein the pigment is an inorganic material and the color of a homogeneous coating of the pigment, measured over a white background, is selected from the group consisting of: a CIELAB L* value of about 30 or less and a chroma value of about 3 or less; a CIELAB hue angle, hab, from about 50 to about 80 degrees, wherein L* is not more than about 85, and the chroma value is greater than 22; a CIELAB hue angle, hab, from about 80 to about 275 degrees, wherein L* is not more than about 80, and the chroma value is greater than about 10; and a CIELAB hue angle, hab, from not less than about 275 to not more than about 50 degrees, wherein L* is not more than about 85, and the chroma value is greater than about 9. The pigments may be used in a variety of applications including cosmetics, plastics, automotive, or architectural coatings.
Abstract translation: 一种珠光颜料，其中所述颜料是无机材料，并且在白色背景上测量的颜料均匀涂层的颜色选自：大约30或更小的CIELAB L *值和色度值 约3或更小; CIELAB色调角hab约为50至约80度，其中L *不大于约85，色度值大于22; CIELAB色调角hab约为80至约275度，其中L *不大于约80，色度值大于约10; 以及不小于约275至不超过约50度的CIELAB色调角hab，其中L *不大于约85，并且色度值大于约9.颜料可以以多种形式使用 的应用，包括化妆品，塑料，汽车或建筑涂料。
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公开(公告)号：US20080118452A1
公开(公告)日：2008-05-22
申请号：US11931658
申请日：2007-10-31
Applicant: Aaron M. Hollman , Stephane Nicolas , Philippe Schottland , Marguerite Debacker , Aurelie Antonowicz , Hai Hui Lin
Inventor： Aaron M. Hollman , Stephane Nicolas , Philippe Schottland , Marguerite Debacker , Aurelie Antonowicz , Hai Hui Lin
CPC classification number: C09C1/0015 , A61K8/0258 , A61K8/19 , A61K2800/412 , A61K2800/436 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/10 , A61Q1/12 , A61Q3/02 , A61Q5/02 , A61Q19/00 , A61Q19/10 , C01P2006/62 , C01P2006/63 , C01P2006/64 , C01P2006/65 , C01P2006/66 , C09C1/0021 , C09C2200/1004 , C09C2200/102 , C09C2200/1087 , C09C2200/301 , C09C2200/302 , C09C2200/304 , C09C2200/306 , C09C2200/407 , C09D5/36
Abstract: A cosmetic containing a pearlescent pigment comprising a substrate and a first layer, wherein the first layer comprises iron oxide, wherein the iron has from about 1% to about 30% Fe(II) and from about 70% to about 99% Fe(III).
Abstract translation: 一种含有珠光颜料的化妆品，其包含基材和第一层，其中所述第一层包含氧化铁，其中所述铁具有约1％至约30％的Fe（II）和约70％至约99％的Fe（III ）。
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公开(公告)号：US20080110371A1
公开(公告)日：2008-05-15
申请号：US11765614
申请日：2007-06-20
Applicant: Aaron M. Hollman , Stephane Nicolas , Philippe Scottland , Marguerite Debacker , Aurelie Antonowicz , Hai Hui Lin
Inventor： Aaron M. Hollman , Stephane Nicolas , Philippe Scottland , Marguerite Debacker , Aurelie Antonowicz , Hai Hui Lin
CPC classification number: C09C1/0015 , C01P2006/62 , C01P2006/63 , C01P2006/64 , C01P2006/65 , C01P2006/66 , C09C1/0021 , C09C2200/1004 , C09C2200/102 , C09C2200/1087 , C09C2200/301 , C09C2200/302 , C09C2200/304 , C09C2200/306 , C09C2200/407 , C09D5/36 , Y10T428/2911 , Y10T428/2982 , Y10T428/2991 , Y10T428/2993 , Y10T428/2995
Abstract: A pearlescent pigment comprising a substrate and a first layer, wherein the first layer comprises iron oxide, wherein the iron has from about 1% to about 30% Fe(II) and from about 70% to about 99% Fe(III). A process for making these pearlescent pigment, comprise reducing a metal oxide substrate with a hydrogen source in the presence of a noble metal catalyst in a liquid medium. The pigments may be used in a variety of applications including cosmetics, plastics, automotive or architectural coatings.
Abstract translation: 一种珠光颜料，其包含基材和第一层，其中所述第一层包含氧化铁，其中所述铁具有约1％至约30％的Fe（II）和约70％至约99％的Fe（III）。 制备这些珠光颜料的方法包括在液体介质中在贵金属催化剂存在下用氢源还原金属氧化物基底。 颜料可用于各种应用，包括化妆品，塑料，汽车或建筑涂料。
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公开(公告)号：US07193007B2
公开(公告)日：2007-03-20
申请号：US10221084
申请日：2001-03-15
Applicant: Yu-Ling Cheng , Hai-Hui Lin
Inventor： Yu-Ling Cheng , Hai-Hui Lin
IPC: C08F290/04 , C08L53/00
CPC classification number: C08L53/00 , A61L27/16 , A61L27/52 , C08F293/00 , C08F297/00 , Y10S524/916
Abstract: The invention relates to a gelable copolymer composition comprising a copolymer in a solvent. The copolymer has the structure A(B)n, wherein the core (A) is soluble in the solvent, the arms (B) are convertible between soluble and insoluble in the solent depending on an environmental condition, and n>1. The composition forms a gel under environmental conditions in which B is insoluble, through formation of B aggregates. Block copolymers comprising polyethylene glycol (PEG) and poly(N-iso-propylacrylamide) (PNIPAAm) having a liquid form at ambient temperature under aqueous conditions and a gel form at body temperature are disclosed. Copolymer compositions according to the invention can be used to form in situ implants useful in slow-release formulations of biologically active molecules
Abstract translation: 本发明涉及在溶剂中包含共聚物的可胶凝共聚物组合物。 共聚物具有结构A（B）n，其中核（A）可溶于溶剂，臂（B）可根据环境条件在可溶性和不溶性之间转化，并且n> 1。 组合物通过形成B聚集体在环境条件下形成凝胶，其中B不溶。 公开了包含聚乙二醇（PEG）和聚环氧乙烷（PNIPAAm）在环境温度和水温条件下具有液态的嵌段共聚物和体温下的凝胶形式。 根据本发明的共聚物组合物可用于形成用于生物活性分子的缓释制剂的原位植入物
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公开(公告)号：US20050020719A1
公开(公告)日：2005-01-27
申请号：US10221084
申请日：2001-03-15
Applicant: Yu-Ling Cheng , Hai-Hui Lin
Inventor： Yu-Ling Cheng , Hai-Hui Lin
IPC: A61L27/16 , A61L27/52 , C08F293/00 , C08F297/00 , C08L53/00 , C08K3/00 , A61F2/00 , C08F20/54 , C08L1/00
CPC classification number: C08L53/00 , A61L27/16 , A61L27/52 , C08F293/00 , C08F297/00 , Y10S524/916
Abstract: The invention relates to a gelable copolymer composition comprising a copolymer in a solvent. The copolymer has the structure A(B)n, wherein the core (A) is soluble in the solvent, the arms (B) are convertible between soluble and insoluble in the solent depending on an environmental condition, and n>1. The composition forms a gel under environmental conditions in which B is insoluble, through formation of B aggregates. Block copolymers comprising polyethylene glycol (PEG) and poly(N-iso-propylacrylamide) (PNIPAAm) having a liquid form at ambient temperature under aqueous conditions and a gel form at body temperature are disclosed. Copolymer compositions according to the invention can be used to form in situ implants useful in slow-release formulations of biologically active molecules.
Abstract translation: 本发明涉及在溶剂中包含共聚物的可胶凝共聚物组合物。 共聚物具有结构A（B）n，其中核（A）可溶于溶剂，臂（B）可根据环境条件在可溶性和不溶性之间转化，并且n> 1。 组合物通过形成B聚集体在环境条件下形成凝胶，其中B不溶。 公开了包含聚乙二醇（PEG）和聚环氧乙烷（PNIPAAm）在环境温度和水温条件下具有液态的嵌段共聚物和体温下的凝胶形式。 根据本发明的共聚物组合物可用于形成用于生物活性分子的缓释制剂的原位植入物。
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