公开(公告)号：US08673197B2

公开(公告)日：2014-03-18

申请号：US13213027

申请日：2011-08-18

申请人： Makoto Etoh ,  Hiroaki Goto ,  Atsushi Kikuchi

发明人： Makoto Etoh ,  Hiroaki Goto ,  Atsushi Kikuchi

IPC分类号： B29C37/00

CPC分类号： B32B27/08 ,  B29C43/146 ,  B29C43/203 ,  B29C43/361 ,  B29C2043/3433 ,  B29L2001/00 ,  B32B27/325 ,  B32B2307/724 ,  B32B2307/7242 ,  B32B2435/02

摘要： A multi-layer structure comprising a functional resin layer obtained by covering a core layer of a base body resin or a second functional resin with a shell layer of a first functional resin, and a base body resin layer containing the functional resin layer therein. The layers of the functional resins are formed at positions where they are allowed to exhibit their functions to a sufficient degree, a plurality of functions can be imparted, and a molten resin mass having the above multi-layer structure can be formed by the compression-forming.

摘要翻译： 一种多层结构，包括通过用第一功能性树脂的壳层覆盖基体树脂或第二功能性树脂的芯层而获得的功能性树脂层和在其中含有功能性树脂层的基体树脂层。 功能性树脂层形成在能够充分展现其功能的位置上，可以赋予多种功能，通过压缩成型法形成具有上述多层结构的熔融树脂块， 成型。

公开(公告)号：US08569241B2

公开(公告)日：2013-10-29

申请号：US13532394

申请日：2012-06-25

申请人： Kazuhito Ohsawa ,  Naoto Uchida ,  Kohji Ohki ,  Hiroaki Goto

发明人： Kazuhito Ohsawa ,  Naoto Uchida ,  Kohji Ohki ,  Hiroaki Goto

IPC分类号： A01N37/18 ,  A61K38/00 ,  C07K16/00

CPC分类号： A61K38/04 ,  C07K7/08

摘要： Provided are a composition for improving the brain function, which can be orally taken at a low dose, and a method therefor. The composition for improving the brain function contains, as the active ingredient, X-Pro-Pro-Leu-Thr-Gln-Thr-Pro-Val-Val-Val-Pro-Pro-Phe-Leu-Gln-Pro-Glu-Y (wherein X is nil or represents Ile or Asn-Ile; and Y is nil or represents Val-Met), X-Val-Val-Val-Pro-Pro-Phe-Leu-Gln-Pro-Glu-Y (wherein X is abscent or represents Thr-Gln-Thr-Pro, Pro-Leu-Thr-Gln-Thr-Pro, Leu-Thr-Gln-Thr-Pro or Pro; and Y is abscent or represents Val-Met), or a salt of the same. The method for improving the brain function comprises administering said peptide or a salt of the same.

摘要翻译： 提供了可以以低剂量口服摄取的用于改善脑功能的组合物及其方法。 用于改善脑功能的组合物含有作为活性成分的X-Pro-Pro-Leu-Thr-Gln-Thr-Pro-Val-Val-Val-Pro-Pro-Phe-Leu-Gln-Pro-Glu- Y（其中X为零或表示Ile或Asn-Ile; Y为无或表示Val-Met），X-Val-Val-Val-Pro-Pro-Phe-Leu-Gln-Pro-Glu-Y X缺失或表示Thr-Gln-Thr-Pro，Pro-Leu-Thr-Gln-Thr-Pro，Leu-Thr-Gln-Thr-Pro或Pro; Y为缺失或代表Val-Met） 盐相同。 改善脑功能的方法包括施用所述肽或其相同的盐。

公开(公告)号：US08262677B2

公开(公告)日：2012-09-11

申请号：US12241131

申请日：2008-09-30

申请人： Hiroaki Goto

发明人： Hiroaki Goto

IPC分类号： A61B17/10

CPC分类号： A61B17/12013 ,  A61B1/00087 ,  A61B1/273 ,  A61B17/3478 ,  A61B2017/00292 ,  A61B2017/00296 ,  A61B2017/00367 ,  A61B2017/00535 ,  A61B2017/12018 ,  A61B2017/347

摘要： A ligation tool for endoscope includes an overtube having an insertion lumen 21a made of a flexible material, which permits an insertion portion 11 of the endoscope to be inserted therethrough so as to advance and retreat, an O-ring 22 for ligation attached to a distal end of the overtube, and a operation wire 24 which is locked to the O-ring for ligation, has a distal portion extending to the proximal side of the overtube, and is operated to be pulled or pushed at its proximal side, thereby separating the O-ring for ligation from the tip of the overtube. According to this ligation tool for endoscope, time and effort taken to set the ligation tool for endoscope in the endoscope becomes unnecessary, a sufficient field of vision of the endoscope can be secured, and the curving performance of the tip of the insertion portion of the endoscope does not deteriorate. Furthermore, this ligation tool is also advantageous when endoscopic sclerotherapy is performed together.

摘要翻译： 用于内窥镜的结扎工具包括具有由柔性材料制成的插入内腔21a的外套管，其允许内窥镜的插入部分11插入其中以便前后退;用于连接的远端O形环22， 外套管的端部和锁定到O形环用于结扎的操作线24具有延伸到外套管的近侧的远侧部分，并且被操作以在其近侧被拉动或推动，从而将 O形圈用于从外套管的尖端连接。 根据该内窥镜用连接工具，不需要在内窥镜中设置用于内窥镜的结扎工具所花费的时间和精力，能够确保内窥镜的足够的视野，并且，插入部的尖端的弯曲性能 内窥镜不会恶化。 此外，当一起进行内镜硬化治疗时，该连接工具也是有利的。

公开(公告)号：US20110304069A1

公开(公告)日：2011-12-15

申请号：US13213027

申请日：2011-08-18

申请人： Makoto ETOH ,  Hiroaki GOTO ,  Atsushi KIKUCHI

发明人： Makoto ETOH ,  Hiroaki GOTO ,  Atsushi KIKUCHI

IPC分类号： B29C37/00

CPC分类号： B32B27/08 ,  B29C43/146 ,  B29C43/203 ,  B29C43/361 ,  B29C2043/3433 ,  B29L2001/00 ,  B32B27/325 ,  B32B2307/724 ,  B32B2307/7242 ,  B32B2435/02

摘要： A multi-layer structure comprising a functional resin layer obtained by covering a core layer of a base body resin or a second functional resin with a shell layer of a first functional resin, and a base body resin layer containing the functional resin layer therein. The layers of the functional resins are formed at positions where they are allowed to exhibit their functions to a sufficient degree, a plurality of functions can be imparted, and a molten resin mass having the above multi-layer structure can be formed by the compression-forming.

摘要翻译： 一种多层结构，包括通过用第一功能性树脂的壳层覆盖基体树脂或第二功能性树脂的芯层而获得的功能性树脂层和在其中含有功能性树脂层的基体树脂层。 功能性树脂层形成在能够充分展现其功能的位置上，可以赋予多种功能，通过压缩成型法形成具有上述多层结构的熔融树脂块， 成型。

公开(公告)号：US20090177030A1

公开(公告)日：2009-07-09

申请号：US12323716

申请日：2008-11-26

申请人： Hiroaki Goto

发明人： Hiroaki Goto

IPC分类号： A61B1/00

CPC分类号： A61B17/32002 ,  A61B1/012 ,  A61B17/32056 ,  A61B18/1492 ,  A61B2017/00296 ,  A61B2017/320032 ,  A61B2018/00488 ,  A61B2018/00494 ,  A61B2018/1407 ,  A61B2018/144 ,  A61B2018/1495

摘要： An endoscopic incision system includes: an endoscope; a cylindrical member for covering at least a distal end of an insertion section of the endoscope; and at least an incision section for incising a living tissue, the incision section being provided to a distal end of the cylindrical member and being capable of being exposed from the distal end of the cylindrical member outwardly. In this configuration, the radially expanding incision section will not be twisted or bent, and the incision section prevented from inadvertent fall-off can maintain the desirable shape when it is operated and rotated.

摘要翻译： 内窥镜切割系统包括：内窥镜; 用于覆盖所述内窥镜的插入部的至少前端的筒状部件; 以及至少一个用于切割生物体组织的切口部分，所述切口部分设置在所述圆柱形部件的远端并且能够从所述圆柱形部件的远端向外露出。 在这种构造中，径向扩张的切口部分不会被扭曲或弯曲，并且防止切口部分无意中脱落时可以在操作和旋转时保持期望的形状。

公开(公告)号：US20090137867A1

公开(公告)日：2009-05-28

申请号：US12277508

申请日：2008-11-25

申请人： Hiroaki GOTO

发明人： Hiroaki GOTO

IPC分类号： A61B1/018

CPC分类号： A61B17/320725 ,  A61B1/00135 ,  A61B1/018 ,  A61B17/320758 ,  A61B18/1492 ,  A61B2017/00336 ,  A61B2017/0034 ,  A61B2017/00902

摘要： An endoscope treatment system includes: an endoscope; and a treatment tool that has a sheath that is inserted in a channel of an insertion portion of the endoscope, in which projection portions that project outward from the sheath in the radial direction are provided, and engagement portions that engage the projection portions are provided near the channel of the endoscope.

摘要翻译： 内窥镜处理系统包括：内窥镜; 以及处理工具，其具有插入在所述内窥镜的插入部的通道中的护套，所述护套设置有从所述护套向径向突出的突出部，并且与所述突出部接合的接合部靠近 内窥镜的通道。

公开(公告)号：US20090125037A1

公开(公告)日：2009-05-14

申请号：US12241131

申请日：2008-09-30

申请人： Hiroaki GOTO

发明人： Hiroaki GOTO

IPC分类号： A61B17/128

CPC分类号： A61B17/12013 ,  A61B1/00087 ,  A61B1/273 ,  A61B17/3478 ,  A61B2017/00292 ,  A61B2017/00296 ,  A61B2017/00367 ,  A61B2017/00535 ,  A61B2017/12018 ,  A61B2017/347

摘要： A ligation tool for endoscope includes an overtube having an insertion lumen 21a made of a flexible material, which permits an insertion portion 11 of the endoscope to be inserted therethrough so as to advance and retreat, an O-ring 22 for ligation attached to a distal end of the overtube, and a operation wire 24 which is locked to the O-ring for ligation, has a distal portion extending to the proximal side of the overtube, and is operated to be pulled or pushed at its proximal side, thereby separating the O-ring for ligation from the tip of the overtube. According to this ligation tool for endoscope, time and effort taken to set the ligation tool for endoscope in the endoscope becomes unnecessary, a sufficient field of vision of the endoscope can be secured, and the curving performance of the tip of the insertion portion of the endoscope does not deteriorate. Furthermore, this ligation tool is also advantageous when endoscopic sclerotherapy is performed together.

摘要翻译： 用于内窥镜的结扎工具包括具有由柔性材料制成的插入内腔21a的外套管，其允许内窥镜的插入部分11插入其中以便前后退;用于连接的远端O形环22， 外套管的端部和锁定到O形环用于结扎的操作线24具有延伸到外套管的近侧的远侧部分，并且被操作以在其近侧被拉动或推动，从而将 O形圈用于从外套管的尖端连接。 根据该内窥镜用连接工具，不需要在内窥镜中设置用于内窥镜的结扎工具所花费的时间和精力，能够确保内窥镜的足够的视野，并且，插入部的尖端的弯曲性能 内窥镜不会恶化。 此外，当一起进行内镜硬化治疗时，该连接工具也是有利的。

公开(公告)号：US20090099414A1

公开(公告)日：2009-04-16

申请号：US12093706

申请日：2005-11-14

申请人： Hiroaki Goto ,  Masaru Yuasa ,  Kenichi Nishina ,  Tatsuya Saito

发明人： Hiroaki Goto ,  Masaru Yuasa ,  Kenichi Nishina ,  Tatsuya Saito

IPC分类号： A61B1/018 ,  A61B1/01

CPC分类号： A61B1/018 ,  A61B1/267 ,  A61B10/04 ,  A61B10/06 ,  A61B2010/0216 ,  A61B2017/347 ,  A61B2090/034 ,  A61B2090/062 ,  A61B2090/3784

摘要： A method of performing diagnosis or treatment perendoscopically in which a guide catheter is inserted inside a body, and the guide catheter is made to protrude beyond a distal end portion of the endoscope; and in which a first diagnosis or treatment is performed by inserting a medical treatment device that performs the diagnosis or treatment of the body inside the guide catheter, and causing this medical treatment device to protrude by a first predetermined distance from the guide catheter; and in which the medical treatment device is extracted from the guide catheter; and in which a second diagnosis or treatment is performed by inserting a medical treatment device into the guide catheter, and causing the medical treatment device to protrude by a second distance which is adjusted in accordance with the first predetermined distance.

摘要翻译： 一种执行诊断或治疗的方法，其中引导导管插入体内，导引导管突出超过内窥镜的远端部分; 并且其中通过将执行身体在导管内的诊断或治疗的医疗处理装置插入并使该医疗装置从导向导管突出第一预定距离来执行第一诊断或治疗; 并且其中所述医疗装置从所述导向导管拔出; 并且其中通过将医疗处理装置插入导管中进行第二诊断或治疗，并使医疗处理装置突出第二距离，第二距离是根据第一预定距离调节的。

公开(公告)号：US20080300594A1

公开(公告)日：2008-12-04

申请号：US12117401

申请日：2008-05-08

申请人： Hiroaki GOTO

发明人： Hiroaki GOTO

IPC分类号： A61B17/3209

CPC分类号： A61B17/320725 ,  A61B17/00234 ,  A61B17/3209 ,  A61B2017/00818 ,  A61B2017/22038 ,  A61B2017/22069 ,  A61B2017/320733 ,  A61B2090/062

摘要： An incision tool includes a sheath; a plurality of wires that are inserted through an internal space of the sheath, and that, as a result of a portion thereof being inserted through both first wire insertion through holes that are provided in a distal end portion of the sheath and second wire insertion through holes that are provided on the sheath distal end side of the first wire insertion through holes, are exposed on the outside of the sheath between the first wire insertion through holes and the second wire insertion through holes, and that receive high-frequency current; and an operating unit that is connected to a base end side of the wires and that adjusts the length of the exposed portions of the wires which are exposed on the outside of the sheath by moving forwards or backwards relatively to the sheath in the longitudinal direction of the wires.

摘要翻译： 切口工具包括护套; 插入穿过护套的内部空间的多个电线，并且由于其一部分插入通过设置在护套的远端部分中的第一电线插入通孔和第二电线插入通过的多个电线 设置在第一线插入通孔的护套前端侧的孔暴露在第一线插入通孔和第二线插入通孔之间的鞘的外侧，并接收高频电流; 以及操作单元，其连接到所述电线的基端侧，并且通过相对于所述护套沿所述护套的纵向方向向前或向后移动来调节暴露在所述护套的外侧上的电线的暴露部分的长度 电线。

公开(公告)号：US20080152915A1

公开(公告)日：2008-06-26

申请号：US12016228

申请日：2008-01-18

申请人： Takayuki Ishihara ,  Hiroaki Goto ,  Yoshihiro Ohta ,  Yuji Yamaguchi ,  Go Saito

发明人： Takayuki Ishihara ,  Hiroaki Goto ,  Yoshihiro Ohta ,  Yuji Yamaguchi ,  Go Saito

IPC分类号： B32B27/00 ,  C08F110/02

CPC分类号： C08L23/00 ,  C08J3/226 ,  C08J2323/08 ,  C08J2423/00 ,  C08L23/0815 ,  C08L2205/02 ,  Y10S525/902 ,  Y10T428/2998 ,  C08L2666/02 ,  C08L2666/06

摘要： A high-quality oxygen-absorbing resin composition which is obtained without suffering resin scorching. Also provided are pellets for the oxygen-absorbing resin composition which comprise a thermoplastic resin (A) and an oxidation catalyst. After the pellets are mixed with a trigger resin and a thermoplastic resin (C), the trigger resin functions as a trigger to cause the oxidation of the thermoplastic resins (A) and (C) to proceed. As a result, the resultant composition absorbs oxygen.

摘要翻译： 高品质的氧吸收树脂组合物，其不会发生树脂烧焦而得到。 还提供了包含热塑性树脂（A）和氧化催化剂的氧吸收性树脂组合物的粒料。 在颗粒与触发树脂和热塑性树脂（C）混合之后，触发树脂用作引发热塑性树脂（A）和（C）的氧化进行的触发剂。 结果，所得组合物吸收氧气。