Process for making an optically active mixture of an N-acyl-amino acid
or ester containing at least two chiral centers
    6.
    发明授权
    Process for making an optically active mixture of an N-acyl-amino acid or ester containing at least two chiral centers 失效
    制备含有至少两个手性中心的N-酰基 - 氨基酸或酯的光学活性混合物的方法

    公开(公告)号:US4929755A

    公开(公告)日:1990-05-29

    申请号:US943480

    申请日:1986-12-19

    CPC classification number: C07C231/10 C07C227/30 C07C231/16

    Abstract: In the process of hydrocarboxylating an .alpha.-enamide with CO and H.sub.2 O or an organic hydroxyl compound to produce an N-acyl-.alpha.-amino acid or ester, respectively, the improvement comprising using as the .alpha.-enamide reactant, an .alpha.-enamide which has a chiral center that is essentially all L or D, thereby producing a reaction mixture containing diastereomeric N-acyl-.alpha.-amino acids or esters having two chiral centers, said mixture having essentially no enantiomeric pairs.

    Abstract translation: 在用CO和H 2 O或有机羟基化合物分别加氢羧化α-烯酰胺以产生N-酰基-α-氨基酸或酯的过程中,改进包括使用α-烯酰胺反应物,α-烯酰胺, 具有基本上全部为L或D的手性中心,从而产生含有非对映体N-酰基-α-氨基酸或具有两个手性中心的酯的反应混合物,所述混合物基本上没有对映异构体对。

    1,6-hexanediamides from 3-pentenamides
    7.
    发明授权
    1,6-hexanediamides from 3-pentenamides 失效
    来自3-戊烯酰胺的1,6-己二胺

    公开(公告)号:US4847411A

    公开(公告)日:1989-07-11

    申请号:US730219

    申请日:1985-05-03

    CPC classification number: C07C237/00

    Abstract: A process for making a diamide of the formula ##STR1## by reacting a monoamide compound of the formula ##STR2## with CO and an amine or ammonia of the formula R.sub.7 R.sub.8 NH in the liquid phase under essentially anhydrous conditions at a temperature in the range from 120.degree. to 210.degree. C., where each of R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 is selected independently from H and a C.sub.1 to C.sub.12 hydrocarbyl containing no ethylenic or acetylenic unsaturation.

    Abstract translation: 通过在基本上无水的条件下,在120℃的温度下,使液体相中的式(I)所示的单酰胺化合物与CO和式R7R8NH的胺或氨反应,制备式IMA的二酰胺的方法: 其中R 1,R 2,R 3,R 4,R 5,R 6,R 7和R 8各自独立地选自H和不含烯属或炔属不饱和的C 1至C 12烃基。

    Method of producing adiponitrile
    9.
    发明授权
    Method of producing adiponitrile 失效
    生产己二腈的方法

    公开(公告)号:US4681968A

    公开(公告)日:1987-07-21

    申请号:US705937

    申请日:1985-02-26

    CPC classification number: C07C255/00

    Abstract: A first row transition metal catalyzed procedure for the production of adiponitrile from acrylonitrile comprising mixing a first row transition metal salt, acrylonitrile, metallic reducing agent and solvent, heating the solution, and adding a quench solution to the mixture comprising a proton donor material having a 0

    Abstract translation: 用于从丙烯腈制备己二腈的第一排过渡金属催化方法,包括混合第一排过渡金属盐,丙烯腈,金属还原剂和溶剂,加热溶液,以及向混合物中加入骤冷溶液,该混合物包含具有 0

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