Abstract:
Resettable circuit interrupting devices, such as GFCI devices, that include reverse wiring protection, and optionally an independent trip portions and/or a reset lockout portion are provided. The reverse wiring protection operates at both the line and load sides of the device so that in the event line side wiring to the device is improperly connected to the load side, fault protection for the device remains. The trip portion operates independently of a circuit interrupting portion used to break the electrical continuity in one or more conductive paths in the device. The reset lockout portion prevents the reestablishing of electrical continuity in open conductive paths if the circuit interrupting portion is non-operational or if an open neutral condition exists.
Abstract:
A system (100) for creating web content that is activatable for delivery to a communications service (101) is closed. In one embodiment, the system includes an interface (102) for receiving content configuration information from a content provider (104) and an engine (106) for processing the content configuration information (102) to generate program code for distribution to one or more nodes (108) of a computer network (110). Each node (108) executes the program code to display, on execution of the program code, an activatable control to a content viewer (111). The program code is configured to respond to a content viewer (111) activating the control to receive a communications service identifier from the content viewer (111) and to initiate delivery of content to the identified communications service in accordance with the configuration information. A method of creating web content that is activatable for delivery to a communications service is also disclosed.
Abstract:
The invention relates to a bispecific molecule comprising a first recognition binding moeity that binds a Cab-like receptor cross-linked using a poly-(ethylene glycol) (“PEG”) linker with one or more second recognition binding moieties that bind a molecule. The invention also relates to methods of producing such bispecific molecules and to therapeutic uses of such bispecific molecules.
Abstract:
The invention provides a bispecific molecule comprising an antibody that binds a C3b-like to one or more antigen-binding antibody fragments, each of which binds an antigenic molecule. The invention also provides methods of producing such bispecific molecules and to therapeutic uses of such bispecific molecules. The invention further provides bispecific molecules in which the antigen-binding antibody fragment binds the protective antigen protein of Bacillus anthracis (Anthrax) exotoxin for treatment of Anthrax infection.
Abstract:
The present invention relates to antibiotic compounds and intermediates useful in their preparation. Many of the antibiotic compounds contain a substituted isoxazolidine ring. The invention also relates to pharmaceutical compositions containing a compound of the invention. The invention further provides processes for the preparation of compounds of the invention, and methods for their use as therapeutic agents.
Abstract:
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.
Abstract:
A tire pressure monitoring system (12) for a vehicle (10) has a plurality of tires (14a, b, c and d) in respective rolling locations and a spare tire (14e) generating a spare tire identification. A controller (22) starts the timer (44) and sets a tire status to a rolling status, a pending rolling status, a spare status or a pending spare status in response to the timer and the vehicle speed. The controller (22) stores the status and the spare tire identification in the memory.
Abstract:
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.
Abstract:
A measuring cell for measuring electrical conductivity of liquids having a bore which in operation is contacted by a liquid, the conductivity of which is to be measured and a plurality of electrodes spaced along the bore and forming part of the bore surface, the electrodes being of coaxial annular form and including a first and a fourth electrode which constitute current electrodes for connection to a controllable AC current supply, a second and third electrode between the current electrodes and constituting voltage electrodes for connection to a high input impedance amplifier provided with means for employing the amplifier output to control the AC current supply to maintain sensibly constant the voltage at the voltage electrodes and a fifth electrode of annular form coaxial with the first to fourth electrodes and for connection to the first electrode by way of a buffer amplifier presenting a high impedance to the first electrode and a low impedance to the fifth electrode and located on the side of the first electrode remote from the fourth and voltage electrodes.