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    DEVICE TO DELIVER MAGNESIUM IN PEG FORMULATION
    1.
    发明申请
    DEVICE TO DELIVER MAGNESIUM IN PEG FORMULATION 有权
    在PEG配方中提供镁的装置

    公开(公告)号：US20100249699A1

    公开(公告)日：2010-09-30

    申请号：US12411537

    申请日：2009-03-26

    申请人： Josee ROY ,  Toya D. Kimble ,  Jeffery C. Marx

    发明人： Josee ROY ,  Toya D. Kimble ,  Jeffery C. Marx

    IPC分类号： A61M37/00 ,  B65D25/08

    CPC分类号： A61J1/2093 ,  A61J1/10 ,  A61J1/2027 ,  A61J1/2089 ,  A61J2205/20 ,  A61K9/0019 ,  A61K33/06

    摘要： A container supplies a medicinal formulation that includes a hydrophilic polymer and an active agent capable of bonding to the polymer. The container includes a first compartment for storing the polymer and a second compartment fluidly isolated from the first compartment for storing the active agent. A frangible barrier is shared between the compartments. A fluidic outlet is disposed on the container to dispense the medicinal formulation. Dispensing of the medicinal formulation includes rupturing the frangible barrier, mixing the polymer and active agent together to form the medicinal formulation, and administering the medicinal formulation provided from the fluidic outlet to a patient. The polymer can be PEG, while the active agent can be magnesium.

    摘要翻译： 容器提供包含亲水性聚合物和能够与聚合物结合的活性剂的药物制剂。 容器包括用于储存聚合物的第一隔室和与第一隔室流体隔离以存储活性剂的第二隔室。 隔间之间共享一个脆弱的障碍。 流体出口设置在容器上以分配药物制剂。 药物制剂的分配包括破裂易碎屏障，将聚合物和活性剂混合在一起形成药物制剂，以及将从流体出口提供的药物制剂施用于患者。 聚合物可以是PEG，而活性剂可以是镁。

    Device to deliver magnesium in PEG formulation
    3.
    发明授权
    Device to deliver magnesium in PEG formulation 有权
    在PEG配方中输送镁的装置

    公开(公告)号：US09078808B2

    公开(公告)日：2015-07-14

    申请号：US12411537

    申请日：2009-03-26

    申请人： Josee Roy ,  Toya D. Kimble ,  Jeffery C. Marx

    发明人： Josee Roy ,  Toya D. Kimble ,  Jeffery C. Marx

    IPC分类号： A61J1/20 ,  A61K9/00 ,  A61K33/06 ,  A61J1/10

    CPC分类号： A61J1/2093 ,  A61J1/10 ,  A61J1/2027 ,  A61J1/2089 ,  A61J2205/20 ,  A61K9/0019 ,  A61K33/06

    摘要： A container supplies a medicinal formulation that includes a hydrophilic polymer and an active agent capable of bonding to the polymer. The container includes a first compartment for storing the polymer and a second compartment fluidly isolated from the first compartment for storing the active agent. A frangible barrier is shared between the compartments. A fluidic outlet is disposed on the container to dispense the medicinal formulation. Dispensing of the medicinal formulation includes rupturing the frangible barrier, mixing the polymer and active agent together to form the medicinal formulation, and administering the medicinal formulation provided from the fluidic outlet to a patient. The polymer can be PEG, while the active agent can be magnesium.

    摘要翻译： 容器提供包含亲水性聚合物和能够与聚合物结合的活性剂的药物制剂。 容器包括用于储存聚合物的第一隔室和与第一隔室流体隔离以存储活性剂的第二隔室。 隔间之间共享一个脆弱的障碍。 流体出口设置在容器上以分配药物制剂。 药物制剂的分配包括破裂易碎屏障，将聚合物和活性剂混合在一起以形成药物制剂，以及将从流体出口提供的药物制剂施用于患者。 聚合物可以是PEG，而活性剂可以是镁。

    System for the production of autologus platelet gel useful for the delivery of medicinal and genetic agents
    4.
    发明申请
    System for the production of autologus platelet gel useful for the delivery of medicinal and genetic agents 审中-公开
    用于生产用于输送药物和遗传剂的自体血小板凝胶的系统

    公开(公告)号：US20090026123A1

    公开(公告)日：2009-01-29

    申请号：US12228965

    申请日：2008-08-18

    申请人： Victor D. Dolecek ,  Robert F. Baugh ,  John G. Rivera ,  William F. McKay ,  Jeffery C. Marx

    发明人： Victor D. Dolecek ,  Robert F. Baugh ,  John G. Rivera ,  William F. McKay ,  Jeffery C. Marx

    IPC分类号： B01D33/35

    CPC分类号： A61L24/106

    摘要： A system for the production of a blood component composition is provided. The system includes a centrifuge having a blood reservoir for receiving and separating a blood sample into multiple components; a dispenser disposed outside of the centrifuge having a first collection chamber containing an activation agent and a second collection chamber containing one or more medicinal agents; means for removing a first portion at least one separated blood component from the centrifuge to the first container and a second portion to the second collection chamber, wherein the first collection chamber activates the first portion and stores the resulting clot and thrombin; a filter for separating the thrombin from the clot; and a nozzle for entraining and mixing the thrombin with the second portion containing the one or more medicinal components.

    摘要翻译： 提供了一种用于制备血液成分组合物的系统。 该系统包括具有血液储存器的离心机，用于将血液样品接收和分离成多个部件; 设置在离心机外部的分配器具有含有活化剂的第一收集室和含有一种或多种药剂的第二收集室; 用于将第一部分至少一个分离的血液成分从离心机移除到第一容器的装置，以及将第二部分移除到第二收集室的装置，其中第一收集室激活第一部分并储存所得凝块和凝血酶; 用于从凝块分离凝血酶的过滤器; 以及用于夹带和混合凝血酶与含有一种或多种药物成分的第二部分的喷嘴。

    Method for the production of a blood component composition
    5.
    发明授权
    Method for the production of a blood component composition 有权
    血液成分组合物的制造方法

    公开(公告)号：US07413652B2

    公开(公告)日：2008-08-19

    申请号：US11115076

    申请日：2005-04-26

    申请人： Victor D. Dolecek ,  Robert F. Baugh ,  John G. Rivera ,  William F. McKay ,  Jeffery C. Marx

    发明人： Victor D. Dolecek ,  Robert F. Baugh ,  John G. Rivera ,  William F. McKay ,  Jeffery C. Marx

    IPC分类号： B01D21/26 ,  C12N5/08

    CPC分类号： A61L26/0057 ,  A61L24/0005 ,  A61L24/106 ,  A61M1/3693 ,  A61M2202/0415 ,  A61M2202/0427 ,  A61M2205/331 ,  Y10T436/25375

    摘要： A system for the production of a blood component composition is provided. The system includes a centrifuge having a blood reservoir for receiving and separating a blood sample into multiple components; a dispenser disposed outside of the centrifuge having a first collection chamber containing an activation agent and a second collection chamber containing one or more medicinal agents; means for removing a first portion at least one separated blood component from the centrifuge to the first container and a second portion to the second collection chamber, wherein the first collection chamber activates the first portion and stores the resulting clot and thrombin; a filter for separating the thrombin from the clot; and a nozzle for entraining and mixing the thrombin with the second portion containing the one or more medicinal components.

    摘要翻译： 提供了一种用于制备血液成分组合物的系统。 该系统包括具有血液储存器的离心机，用于将血液样品接收和分离成多个部件; 设置在离心机外部的分配器具有含有活化剂的第一收集室和含有一种或多种药剂的第二收集室; 用于将第一部分至少一个分离的血液成分从离心机移除到第一容器的装置，以及将第二部分移除到第二收集室的装置，其中第一收集室激活第一部分并储存所得凝块和凝血酶; 用于从凝块分离凝血酶的过滤器; 以及用于夹带和混合凝血酶与含有一种或多种药物成分的第二部分的喷嘴。

    System for the production of an autologous thrombin
    7.
    发明授权
    System for the production of an autologous thrombin 有权
    用于生产自体凝血酶的系统

    公开(公告)号：US06719901B2

    公开(公告)日：2004-04-13

    申请号：US09832517

    申请日：2001-04-09

    申请人： Victor D. Dolecek ,  Robert F. Baugh ,  John G. Rivera ,  William F. McKay ,  Jeffery C. Marx

    发明人： Victor D. Dolecek ,  Robert F. Baugh ,  John G. Rivera ,  William F. McKay ,  Jeffery C. Marx

    IPC分类号： B01D2116

    CPC分类号： A61L26/0057 ,  A61L24/0005 ,  A61L24/106 ,  A61M1/3693 ,  A61M2202/0415 ,  A61M2202/0427 ,  A61M2205/331 ,  Y10T436/25375

    摘要： A system for the production of autologous thrombin, comprising a centrifuge including a blood reservoir for receiving and separating an autologous anticoagulated blood sample having multiple inactive blood components and means for removing at least one of said inactive blood components upon separation, and a dispenser having at least two collection chambers for receiving said at least one of said inactive blood components, wherein a first collection chamber activates a first portion of said inactive blood component and stores the resulting coagulated blood component comprising a clot and said autologous thrombin.

    摘要翻译： 一种用于生产自体凝血酶的系统，包括离心机，其包括用于接收和分离具有多个非活性血液成分的自体抗凝血液样品的血液储存器和用于在分离时去除所述非活性血液成分中的至少一种的装置，以及分配器， 用于接收所述至少一种所述非活性血液成分的至少两个收集室，其中第一收集室激活所述非活性血液成分的第一部分并储存所产生的凝血血液成分，所述血液成分包含凝块和所述自体凝血酶。