Gas turbine engine blade tip clearance apparatus and method
    5.
    发明申请
    Gas turbine engine blade tip clearance apparatus and method 有权
    燃气轮机发动机叶片间隙装置及方法

    公开(公告)号:US20060140755A1

    公开(公告)日:2006-06-29

    申请号:US11025435

    申请日:2004-12-29

    Abstract: A gas turbine engine is provided that includes one or more rotor assemblies, one or more shroud segments, and an actuator. The rotor assemblies are rotatable around an axially extending rotational axis, and each rotor assembly has a plurality of blades. Each blade has a blade tip. The one or more shroud segments each has a blade seal surface disposed radially outside of the one or more rotor assemblies. The blade tips and blade seal surfaces (collectively referred to as the blade seal surface) have mating conical geometries and a clearance distance extending between the blade tips and blade seal surface. The blade tips and blade seal surface are disposed at an angle relative to the axial centerline of the engine, which angle is greater than zero. The actuator is selectively operable to axially move one or both of the shroud segments and rotor assemblies relative to the other of the shroud segments and rotor assemblies to alter the clearance distance.

    Abstract translation: 提供了一种燃气涡轮发动机,其包括一个或多个转子组件,一个或多个护罩段和致动器。 转子组件可围绕轴向延伸的旋转轴线旋转,并且每个转子组件具有多个叶片。 每个叶片都有一个叶片尖端。 一个或多个护罩段各自具有设置在一个或多个转子组件的径向外侧的叶片密封表面。 叶片尖端和叶片密封表面(统称为叶片密封表面)具有匹配的圆锥形几何形状和在叶片尖端和叶片密封表面之间延伸的间隙距离。 叶片尖端和叶片密封表面相对于发动机的轴向中心线成角度设置,该角度大于零。 致动器可选择性地可操作以相对于护罩段和转子组件中的另一个轴向移动护罩段和转子组件中的一个或两个,以改变间隙距离。

    Bulk bag filling system
    6.
    发明申请
    Bulk bag filling system 失效
    散装袋灌装系统

    公开(公告)号:US20050241728A1

    公开(公告)日:2005-11-03

    申请号:US11119872

    申请日:2005-05-02

    CPC classification number: B65B1/04 B65B43/54

    Abstract: A bulk bag filling system includes a frame having a base, a fill carriage coupled to the frame and a rotary carriage. The fill carriage is alignable with a fill port for receiving a bulk material. The rotary carriage includes a plurality of bag loop hangers for receiving bag loops of a bag to be filled. The rotary carriage is movably coupled to the fill carriage and a spout, for receiving a neck of the bag to be filled, extends through the rotary carriage. The spout is alignable with the fill port.

    Abstract translation: 散装袋填充系统包括具有基座的框架,联接到框架的填充托架和旋转托架。 填充托架可与用于接收散装材料的填充口对齐。 旋转托架包括多个用于接收待填充袋的袋环的袋环吊架。 旋转托架可移动地联接到填充托架,并且用于接收要填充的袋的颈部的出口延伸穿过旋转托架。 喷嘴可与填充口对齐。

    Mass spectrometry assays for identifying compounds that activate deacetylases
    9.
    发明授权
    Mass spectrometry assays for identifying compounds that activate deacetylases 有权
    用于鉴定激活脱乙酰酶的化合物的质谱测定

    公开(公告)号:US08304206B2

    公开(公告)日:2012-11-06

    申请号:US12085839

    申请日:2006-12-01

    CPC classification number: G01N33/6851 C12Q1/25 G01N33/6842 G01N2333/98

    Abstract: Provided are methods for determining the activity of proteins that modulate the acetylation state of a protein substrate. The methods may be used for determining both acetyltransferase activity and deacetylase activity. The methods utilize mass spectrometry for determining the acetylation state of a substrate peptide. The methods may also be used to identify compounds that modulate the activity of a protein having acetyltransferase or deacetylase activity. In some embodiments, a compound that modulates a deacetylase is an activator of the deacetylase.

    Abstract translation: 提供了用于测定调节蛋白质底物的乙酰化状态的蛋白质的活性的方法。 该方法可用于测定乙酰转移酶活性和脱乙酰酶活性。 该方法利用质谱法测定底物肽的乙酰化状态。 该方法还可用于鉴定调节具有乙酰转移酶或脱乙酰酶活性的蛋白质的活性的化合物。 在一些实施方案中,调节脱乙酰酶的化合物是脱乙酰酶的活化剂。

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